YPD
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YPD + Mg 200µM + Mn 200µM MG 200 ng ml -1 Supplementary figure S1 Supplementary figure S1 serial dilution assays to show drug susceptibility of C. albicans to MG (200 ng ml -1 ) and supplementation with either 200μM Mg or 200μM Mn
description
Supplementary figure S1. YPD. MG 200 ng ml -1. + Mg 200µM. + Mn 200µM. Supplementary figure S1 serial dilution assays to show drug susceptibility of C. albicans to MG (200 ng ml -1 ) and supplementation with either 200μM Mg or 200μM Mn. Supplementary figure S2. - PowerPoint PPT Presentation
Transcript of YPD
YPD
+ Mg 200µM
+ Mn 200µM
MG 200 ng ml-1
Supplementary figure S1
Supplementary figure S1 serial dilution assays to show drug susceptibility of C. albicans to MG (200 ng ml-1) and supplementation with either 200μM Mg or 200μM Mn
Supplementary figure S2
Supplementary figure S2 MG susceptibility screening of 240 TF Mutants were determined at 300 ng ml-1 by serial dilution assay, only repeatedly sensitive strains were picked up for further analysis.
Supplementary figure S3
PG L
am
ount
(n
mol
per
mg
dry
lipid
wt.
)
PG
L co
mpo
sitio
n (%
of n
orm
aliz
ed P
GL
mas
s sp
ectr
al s
igna
l)
Figure S3 Sterols and phosphoglycerides (PGLs) composition under MG treatment as compared with untreated cells. The amount of sterols are represented as % of normalized total sterol mass spectral signal and PGL amount is represented as % of normalized PGL mass spectral signal. Values are means ± SD of 5 independent experiments (n=3). PC: Phosphatidyl choline; PE: Phosphatidyl ethanolamine; PI: Phosphatidyl inositol; PS: Phosphatidyl serine; PG: Phosphatidyl glycerol; PA: Phosphatidic acid;Lyso PC: Phosphatidyl choline; Lyso PE: Phosphatidyl ethanolamine; Lyso PG: Phosphatidyl glycerol
stp2Δ
upc2Δ
Supplementary figure S4
Supplementary figure S4 UPC2 and STP2 have common target, RT-PCR showing log2 ratios of MET6 in stp2Δ and upc2Δ as compared to their respective wild-type strains.
