Listeria Ppt

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Listeria sp: Gram+ , , -,+, , .

37C - . ,

L.monocytogenes Gram M , , 0-5 C 30-35 C : (5-10%) - pH (4-5) (, , , ) (, , , (1-70 ) , , ) .

Corynebacteriaceae 16S RNA Clostridium-LactobacillusBacillus L. monocytogenes, L. ivanovii, L. innocua, L. welshimeri, L. seeligeri L. grayi

Listeria monocytogenes 5-10% . Listeriae , , .

Listeria

Listeria -20oC 4 C. 12 .

L. ivanovii ( HIV+). . .

/ 25% .

L. monocytogenes. 1981, 100 . 34 9 . 23 infants born infected, and two live healthy births. 77 30% . .

L. monocytogenes

( ) . . . . . . . . .

Survival of the bacterium within the phagolysosome may be aided by its ability to produce catalase and superoxide dismutase which neutralize the effects of the phagocytic oxidative burst.

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L. monocytogenes (9kb) hly: (Hly, - , () actA: ActA - . plcA: C- . plcB: - mpl: Zn++ prfA: PrfA -

: CD4+ (TH1) CD8+ (TC). .

, , , .