JOURNAL OF NATURAL PRODUCTS®

(LLOYDIA) P u b l i s h e d b y THE AMERICAN SOCIETY OF PHARMACOGNOSY

a n d THE LLOYD LIBRARY A N D MUSEUM

9 1 7 PLUM STREET, CINCINNATI, O H I O 4 5 2 0 2 Editor

J A M E S Ε. R O B B E R S School of Pharmacy and

Pharmacal Sciences Purdue University W e s t Lafayette, Indiana 4 7 9 0 7 F A X (317) 4 9 4 - 7 8 8 0

Associate Editor J E R R Y L. M C L A U G H L I N School of Pharmacy and

Pharmacal Sciences Purdue University W e s t Lafayette, Indiana 4 7 9 0 7

Columbus, Ohio C H I N G - J E R C H A N G West Lafayette, Indiana G E O F F R E Y A. C O R D E L L Chicago, Illinois R A Y M O N D W . D O S K O T C H Columbus, Ohio N O R M A N R. F A R N S W O R T H Chicago, Illinois W I L L I A M F E N I C A L La Jolla, California H E I N Z G. FLOSS Seattle, Washington E D W A R D L E E T E Minneapolis, Minnesota

Editorial Advisory Board

Stockton, California KOJI NAKANISHI New York, New York S. W I L L I A M PELLETIER Athens, Georgia G E O R G E R. P E T T I T Tempe, Arizona J . D A V I D P H I L L I P S O N London, England P I E R R E P O T I E R Gif-sur-Yvette, France

Managing Editor S U S A N C. S T I T E S c/o The Lloyd Library 9 1 7 P lum Street Cincinnati , O h i o 4 5 2 0 2

Associate Editor and Book Review Editor

D A V I D G.I. K I N G S T O N Department of Chemistry Virginia Polytechnic Institute

and State University Blacksburg, Virginia 2 4 0 6 1

J O H N P. R O S A Z Z A Iowa City, Iowa U S H I O S A N K A W A Tokyo, Japan P A U L L. SCHIFF, J R . Pittsburgh, Pennsylvania M A U R I C E S H A M M A University Park, Pennsylvania Y U Z U R U S H I M I Z U Kingston, Rhode Island F R A N K R. STERMITZ Fort Collins, Colorado V A R R O E. TYLER West Lafayette, Indiana R O B E R T V E R P O O R T E Leiden, The Netherlands H I L D E B E R T W A G N E R Munich, West Germany

JOURNAL OF NATURAL PRODUCTS® (Lloydia) (ISSN 0163-3864) is published bimonthly in February, April, June, August, October, and December by The American Society of Pharmacog­nosy at 41 Carleton Drive, Pittsburgh, PA 15243. Second-class postage paid at Pittsburgh, PA, and additional mailing offices. POSTMASTER: Send address changes to JOURNAL OF N A T U ­RAL PRODUCTS®, P.O. Box 13145, Pittsburgh, PA 15243.

All manuscripts and correspondence dealing -with editorial matters should be addressed to the editor. The title word for this journal for use in bibliographic reference is JOURNAL OF NATURAL PROD­UCTS®, abbreviated as J. Nat. Prod.

COMMERCIAL SUBSCRIPTIONS—Subscription orders from libraries, institutions, commercial firms, and similar organizations will be treated as commercial subscriptions. All matters related to com­mercial subscriptions, such as billing, change of address, ordering procedures, etc., should be addressed to: Journal of Natural Products®, c/oDavidJ. Slatkin, Ph.D. , Treasurer, American Society of Pharmacog­nosy, School of Pharmacy, 1104 Salk Hall, University of Pittsburgh, Pittsburgh, PA 15261, U.S.A. Phone (412) 648-8579, FAX (412) 648-1086.

Domestic Commercial Subscriptions: $ 120.00, including all addresses in the United States and pos­sessions, the Dominion of Canada, and the Republic of Mexico.

Foreign Commercial Subscriptions: $ 160.00, sent only by airmail to all other parts of the world, with air postage included in the higher rate.

Orders for subscriptions are due and payable during the last quarter of the calendar year preceding the subscription year.

Single copies: $25.00 plus postage.

P R I N T E D B Y T H E S P A H R A N D G L E N N C O M P A N Y , C O L U M B U S , O H I O 43215 Date of Issue—January 8, 1991

L Y N N R. B R A D Y Seattle, Washington JOHN M. CASSADY

T O M J . M A B R Y Austin, Texas MARVIN H. MALONE