PRP Art & science
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22-Aug-2014Category
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PRP art &science
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- Platelet Rich Plasma Art & science Islam Kassem,BDS,MSc,FDS RCS Consultant oral & maxillofacial Surgeon [email protected]
- Angle Face Left New technology of injection your own blood to get a Youthful Look . . [email protected]
- Why Are Celebrities Injecting Their Faces With Blood? [email protected]
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- Platelet? Anuclear piece of cytoplasm Include hemostasis, -granule,lysosomal granule, dense granules [email protected]
- At least 7 different growth factors that stimulate bone & soft tissue healing PDGF aa,bb,ab TGF b1,b2 VEGF EGF [email protected]
- Days of operation [email protected]
- 7 days later PLT exhausted after 7 days Macrophage by low oxygen tension, acidity, lactate concentration Secrete same growth factors Activated until it is down regulated by the restoration of normal oxygen tension [email protected]
- Day 3rd [email protected]
- 17days Graft is completely permeated by new capillaries Initial osteoid formation Osteoclast resorb osteoid and BMP released New bone formation and maturation [email protected]
- Days 14 [email protected]
- The mechanism of growth factor effects on cells Inactive state [email protected]
- Activation activation [email protected]
- Clinical effects of PRP on bone regeneration Platelet RBC Normal blood PRP [email protected]
- Trabecular areaNative mandible Autogenous BG [email protected]
- Clinical effects of PRP on soft tissue healing Split thickness skin graft donor site healing [email protected]
- 6 days Thrombin side : 5% epithelization 95% granulation tissue PRP side ; 95% epithelization 5% granulation tissue [email protected]
- 6 months Thrombin side : scarring hypo and hyper- pigmentation area PRP side ;less scarring Much less pigmentation change [email protected]
- Patient discomfort Patient discomfort decrease [email protected]
- Epithelization [email protected]
- 6days [email protected]
- 1 months [email protected]
- Contraindications Pre-existing coagulation defect : thrombocytopenia, hypofibrinogenia Hypersensitivity to bovine thrombin [email protected]
- Clinical steps [email protected]
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- Clinical application [email protected]
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- Ridge preservation [email protected]
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