Platelet Rich Plasma Art & science Islam Kassem,BDS,MSc,FDS RCS Consultant oral & maxillofacial Surgeon ikassem@dr.com
Angle Face Left New technology of injection your own blood to get a Youthful Look . . ikassem@dr.com
Why Are Celebrities Injecting Their Faces With Blood? ikassem@dr.com
ikassem@dr.com
Platelet? Anuclear piece of cytoplasm Include hemostasis, -granule,lysosomal granule, dense granules ikassem@dr.com
At least 7 different growth factors that stimulate bone & soft tissue healing PDGF aa,bb,ab TGF b1,b2 VEGF EGF ikassem@dr.com
Days of operation ikassem@dr.com
7 days later PLT exhausted after 7 days Macrophage by low oxygen tension, acidity, lactate concentration Secrete same growth factors Activated until it is down regulated by the restoration of normal oxygen tension ikassem@dr.com
Day 3rd ikassem@dr.com
17days Graft is completely permeated by new capillaries Initial osteoid formation Osteoclast resorb osteoid and BMP released New bone formation and maturation ikassem@dr.com
Days 14 ikassem@dr.com
The mechanism of growth factor effects on cells Inactive state ikassem@dr.com
Activation activation ikassem@dr.com
Clinical effects of PRP on bone regeneration Platelet RBC Normal blood PRP ikassem@dr.com
