m010550.pdf

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Transcript of m010550.pdf

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    BaronM.,"Manicdepressiongenesandthenewmillennium:poisedfordiscovery",Molecular

    Psychiatry,7(2002),342358.

    CraddockN.,ODonovanMC,OwenM.J.,"Thegeneticsofschizophreniaandbipolardisorder:

    dissectingpsychosis",Journal of Medical Genetics,42(2005),193204.

    DikeosD.G.,VassosE,PapadimitriouG.N.,"GeneticcounselinginSchizophrenia",n:Kasper

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    lenges,SecondEdition,InformaHealthcare,UK,2009,p.p.322332.

    KarayiorgouM.,GogosJ.A.,"Schizophreniagenetics:uncoveringpositionalcandidategenes",

    European Journal of Human Genetics,14(2006),512519.

    OwenM.J.,CraddockN.,JablenskyA.,"Thegeneticdecontructionofpsychosis",Schizophrenia

    Bulletin,33(2007),905911.

    .., .., "

    ",,82(2002),4456.

    PapadimitriouG.N.,LinkowskiP.,DelabreC.,MedlewiczJ.,"Suicideonthepaternalandma

    ternalsidesofdepressedpatientswithalifetimehistoryofattemptedsuicide",Acta Psychi-

    atrica Scandinavica,83(1991),417419.

    PapadimitriouG.N.,DikeosD.G.,StefanisC.N.,"PsychiatricgeneticresearchinGreece",Psy-

    chiatric Genetics,9(1999),115121.

    PapadimitriouG.N.,DikeosD.G.,"Howdoesrecentknowledgeontheheredityofschizophrenia

    affectgeneticcounseling?"Current Psychiatry Reports,5(2003),23940

    SchosserA.,McGuffinP.,"Geneticandepigeneticfactorsinschizophrenia",In:KasperS,Pa

    padimitriouGN(eds)Schizophrenia, Biopsychosocial Approaches and Current Challenges,

    SecondEdition,InformaHealthcare,UK,2009,p.p.7886.

    Stefanis C.N., DikeosD.G., PapadimitriouG.N., "Clinical strategies in genetic research", In:

    MendlewiczJ,PapadimitriouGN(eds),Genetics of Mental Disorders Part I. Theoretical As-

    pects,BaillieresClinicalPsychiatry, InternationalPracticeandResearch,BailliereTindall,

    London,1995,I:118.

    StefanisN.C.,HenquetC.,AvramopoulosD.etal.,"COMTVal158Metmoderationofstressin

    ducedpsychosis",Psychol Med 37(2007),16511656.

    StefanisC.N.,StefanisS.C.,"Schizophrenia:Historicalrootsandbriefreviewofrecentresearch

    developments".In:Schizophrenia, Biopsychosocial Approaches and Current Challenges,Sec

    ondEdition,Informahealthcare,UK,2009,p.p.115.

  • 32

    SullivanP.F.,KendlerK.S.,NealeM.C.,"Schizophreniaasacomplextrait:evidencefromameta

    analysisoftwinstudies",Arch Gen Psychiatry60(2003),11871192.

    TheEuropeanNetworkofSchizophrenia.NetworksfortheStudyofGeneEnvironmentInterac

    tions (EUGEI): schizophrenia aetiology:Do geneenvironment interactions hold theKey?

    Schiz Res 2008,102,2126.

  • 33

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    Management of Risk. London, England, Jessica Kingsley, 2000.

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    Charney D.S., "Psychobiological Mechanisms of Resilience and Vulnerability: Implications for

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    Dusek J.A., Otu H.H., Wohlhueter A.L., Bhasin M., Zerbini L.F., Joseph M.G., Benson H.,

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    Moussavi S., Chatterji S., Verdes E., Tandon A., Patel V., Ustun B., "Depression, chronic diseases,

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    Otto M.W., Church T.S., Craft L.L., Greer T.L., Smits J.A.J., Trivedi M.H.., "Exercise for mood

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    Snchez-Villegas A., Delgado-Rodrguez M., Alonso A., Schlatter J., Lahortiga F., Serra Majem

    L., Martnez-Gonzlez M.A., "Association of the Mediterranean Dietary Pattern With the

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    Theleritis C.G., Paparrigopoulos T.J., Papadimitriou G.N., "The importance of efficient depres-

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  • 83

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    ArnoldE.&BoggsK.,Interpersonal Relationships.Professional Commmmunication Skills for

    Nurses,2ndedition,Philadelphia,W.B.SaundersCo.,1995.

    CricknellE.,"AHumanisticperspective",In:WillsonM.(ed.),Occupational Therapy in Short

    Term Psychiatry,London,ChurchillLivingstone,1996.

    BurnardP.,Learning Human Skills,3rdEdition,Oxford,ButterworthHeinemannLtd,1995.

    Hopson B., "Counselling and Helping", In: Holdsworth R. (Ed.), Psychology for Careers

    Counselling,London.Macmillan,1982.

    ., ,,,2004.

    ., ,5.,,1999.

    McLeodJ.,An Introduction to Counselling,Buckingham,OpenUniversityPress,1993.

    RowanS.,Ordinary Ecstasy. Humanistic Psychology in Action,2ndEdition.London.Routledge,

    1988.

    TschudinV.,Counselling Skills for Nurses,4thEdition,London,BalliereTindall,1995.

  • 85

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  • 89

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  • 91

    , ,

    ,

    .

    AngermeyerM.C.,DietrichS.,"Publicbeliefsaboutandattitudestowardspeoplewithmental

    illness:areviewofpopulationstudies",Acta Psychiatr Scand 113(2006),163197.

    Corrigan P.W.&Kleinen P., "The impact ofmental illness stigma" In: P.W. Corrigan (Ed.),

    Practical strategies for research and social change, Washington DC, American Psy

    chologicalAssociation,2005.

    CorriganP.W.,RiverL.P.,LundinR.K.etal,"Threestrategiesforchangingattributionsabout

    severementalillness",Schizophr Bull27(2001),187195.

    GoffmanE.,Stigma: Notes on the management of spoiled identity, London: Penguin books.

    1963.

    EconomouM.,GramandaniC.,RichardsonC.,&StefanisC.,"Publicattitudestowardspeople

    withschizophreniainGreece",World Psychiatry,4(2005),4044.

    LevinsonM.C.,DrussB.G.,DombrowskiE.A.,RosenheckR.A.,"Barriers toprimarymedical

    care among patients at a community mental health center", Psychiatr. Serv. 54 (2003),

    11581160.

    Sartorius N. & Schulze H. Reducing the stigma of mental illness, New York, Cambridge

    UniversityPress(2005)2.

    SchulzeB.&AngermeyerM.C., "Subjective experiences of stigma.A focus group study of

    schizophrenicpatients, their relatives andmental healthprofessionals",Social Science &

    Medicine, 56(2003),299312.

    .,.,.,.,.,"

    :"

    ., 13(3)(2006).

    2843.

    ., ., ., "

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  • 93

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  • 100

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    .., . ,

    , 1994.

    .., (. .) , , , 1990,

    124-28.

    Beck J.S., Cognitive Therapy: Basics and Beyond, New York, Guilford Press, 1995.

    Boeker H., Kleiser M., Lehman D., Jaenke L., Bogerts B., Northoff G., "Executive dysfunction,

    self, and ego pathology in schizophrenia: an exploratory study of neuropsychology and

    personality", Compr Psychiatry, Jan-Feb; 47 (1) (2006), 7-19.

    Bozikas V.P., Kosmidis M.H., Kiosseoglou G., Karavatos A., "Neuropsychological profile of

    cognitively impaired patients with schizophrenia", Comprehensive Psychiatry, Vol. 47, Issue

    2 (2006), p. 136-143.

    Farkas M.D., O Brien W.F., and Nemes P.B., "A graduate level curriculum in psychiatric

    rehabilitation: Filling a need, Psychosocial Rehabilitation Journal,12(2) (1988), 53-66.

    Freeman A., Simon K.M., Beutler L.E., Arkowitz A., Comprehensive Handbook of Cognitive

    Therapy, New York, Plenum Press, 1989.

    Giebler U., Georgescu D., Niethammer M., Thiel C., Cognitive dysfunctions predicting the

    outcome of rehabilitation in schizophrenia, European Psychiatry, Volume 12, Supplement

    2, 1997, Page 156s.

    Griffiths R.D., "Rehabilitation of chronic psychotic patients: An assessment of their psychological

    handicap, an evaluation of the effectiveness of rehabilitation, and observations of the factors,

    which predict outcome", Psychol. Medicine 4 (1974) 316-325.

  • 101

    Hawton K.A., Kirk J., "Problem solving", In: Hawton K.A., Kirk J., Clark D.M. (eds), Cognitive

    behaviour therapy for psychiatric problems. A practical guide, Oxford, Oxford University

    Press 1989, 406-426.

    Lezak M.D., Neuropsychological Assessment, New York, Oxford, Oxford University Press. 1995.

    Karidi M.V., Tzedaki M. & Stefanis N., Self-Stigmatisation Study. First International Conference

    on Reducing Stigma and Discrimination Because of Schizophrenia. Leipzig. Book of

    Abstracts, 45, 2001.

    Karidi M.V., Papakonstantinou K., Stefanis N., Zografou M., Karamouzi G., Skaltsi P., et al,

    "Occupational Abilities and Performance Scale: Reliability-Validity Assessment Factor

    Analysis", Soc Psychiatry Psychiatr Epidemiol 40 (2005) 417-24.

    Karidi M.V., Theleritis C., Stefanis N.C.," Stigma and schizophrenia", Lancet 373 (2009). (9672),

    1335-1336.

    Karidi M.V., Stefanis C.N., Thleritis C., Tzedaki M., Rabavilas A.D., Stefanis N.C., "Perceived

    social stigma, self-concept, and self-stigmatization of patient with schizophrenia", Compr

    Psychiatry 51 (2010), 19-30.

    Karidi .V. (Aeginition Hospital - Greece), Flowerdew J. (Alisa Hospital Scotland). Feliu

    (Hospital Psiqyiatrico Spain), Ferguson A. (Northern Ireland Association for Mental

    Health N. Ireland), Rebeiro N. (Hospital Miguel Bombarda Portugal), Moisiadou E.

    (Centre de Readaptation Greece), Kuna . (Pro Mente Informis Austria), Anderson K.

    (Baggensuddens Therapeutic Community Sweden), Schock I. (Dachverband Psychsozialer

    Germany), Siguroardottir S. (National University Hospital Iceland), McDaid P. (Western

    Health Board Ireland), Helios Model: Promoting Independence, Greece, Published by E.U.

    Helios Programme, 1995.

    Karidi, M.V., Tzedaki M., Kondilis K., Armeniakou A., Karamouzi G., Zografos M., Coccosi

    M., Antonopoulou V., Scaltsi P., Stefanis C.N., Rehabilitation Outcome in Relation to

    Psychosocial - Psychiatric Factors in Psychotic Patients University of Athens, Department

    of Psychiatry, Eginition Hospital, Athens VII World Congress of Psychiatry, Abstracts,

    Session 65 (434), 12-19 October 1989, Athens.

    McClure M.M., Bowie C.R., Patterson T.L., Heaton R.K., Weaver C., Anderson H., Harvey P.D.,

    "Correlations of functional capacity and neuropsychological performance in older patients

    with schizophrenia: evidence for specificity of relationships?", Schizophr Res, 2007 Jan; 89

    (1-3), 330-338.

    Walls R.T., Zane T., Werner T.J., "The Vocational Behavior Checklist" (experimental edition),

    Dunbar, WV: Research and Training Center Press, 1978.

  • 103

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  • 146

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    drug addiction treatment. A researchbased guide, NIH Publication No. 994180 Printed

    October 1999.

    OKANA, : 19992002.

    , , 2002.

    http://www.dart.gov.gr

    http://europa.eu/legislation_summaries

    http://www.ektepn.gr

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  • 147

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  • 148

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    8 (2001), 7-19.

    Hughes P.H., Baldwin D.C., Sheehan D.V., Conrad S., Storr C.L., "Resident physician substance

    use, by specialty", Am J Psychiatry 149 (1992) 1348.

    Jellinek E.M., The disease concept of alcoholism, New Haven, CT, College and University Press,

    1960.

    Liappas I.A., Jenner F.A., Vicente B., "Withdrawal symptom", Journal of the Royal College of

    Physicians of London, 21(3) (1987), 214-218.

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  • 155

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  • 158

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  • 162

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  • 163

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  • 164

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  • 165

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  • 166

    Currie C., Gabhainn .S., Godeau E., Roberts C., Smith R,, Currie D., Picket W., Richter M.,

    Morgan A., Barnekow V., Inequalities in Young Peoples Health. World Health Organization,

    2008.

    Hibell B., Guttormsson U., Ahlstrom S., Balakiereva O., Bjarnason T., Kokkevi A., Kraus L.,

    The 2007 ESPAD report: Substance use among students in 35 European countries. CAN,

    Council of Europe, Pompidou Group, Stockholm, 2009.

    Kokkevi A., Gabhainn .S, Spyropoulou M. and the Risk Behaviour Focus Group of the

    HSBC, "Early initiation of cannabis use: a crossnational European perspective", Journal of

    Adolescent Health, v. 39 (5) (2006), p.712719.

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  • 167

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  • 168

    -WHOQOL (WHO, 1995). -

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  • 169

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  • 171

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  • 172

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    .

  • 173

    Allison P., Locker D., Feine J., "Quality of life: A dynamic construct", Social Science and Medicine

    45 (1997) 221-230.

    Cremieu A., !

    , , , 2009.

    Diener E., Oishi S., Lucas R.E., "Personality, culture, and subjective well being: Emotional and

    cognitive evaluation of life", Annual Review of Psychology 54 (2003) 403-425.

    Elias N., . ,

    , ,1997.

    Frede M., , . , , 2008.

    Ginieri-Coccossis M., Triadafillou E., Tomaras V., Liappas I.A., Christodoulou G.N., Papadimitriou

    G.N., "Quality of life differences between psychiatrically and physically ill individuals: The

    use of WHOQOL-100" Greek version. Available:http://www.annals-general-psychiatry.com/

    content/8/1/23. March 2009.

    Kennedy L., Northcott H., Kinzel C., "Subjective evaluation of well-being: problems and

    prospects", Social Indicators Research 51 (978), 457-474.

    Kickbusch I., "The Contribution of the World Health Organization to a New Public Health and

    Health Promotion", American Journal of Public Health 93(3) (2003), 383-388.

    Lehman A.F., Ward N.C., Linn L.S., "Chronic mental patients: the quality of life issue", American

    Journal of Psychiatry139 (1982), 1271-1276.

    Maynard Keynes J., , ., , 2009.

    Najman J.M., Levine S., "Evaluating the impact of medical care and technologies on the quality of

    life: A review and critique", Social Science and Medicine 15F (1981), 107-115.

    Nutbeam D., "Health Promotion Glossary", Health Promotion International 13(4) (1998) 349-364.

    Orley J., Kuyken W. (Eds), Quality of life Assessment: International perspectives, Springer-Verlag,

    Berlin, Germany, 1994.

    Power M., Bullinger M., Harper A., "The World Health Organization Quality of Life Group: The

    World Health Organization WHOQOL-100: tests of the universality of quality of life in 15

    different cultural groups worldwide", Health Psychology 5 (1999) ,495-505.

    Testa M., Simonson D., "Assessment of Quality-of-Life Outcomes", The New England Journal of

    Medicine 334(13) (1996), 835-840.

    Williams B., , . , , 2009.

    The WHOQOL Group: Study protocol for the World Health Organization project to develop a

  • 174

    quality of life assessment instrument (WHOQOL), Quality of Life Research 2 (1993), 153-159.

    The WHOQOL Group. The World Health Organization Quality of Life assessment (WHOQOL):

    position paper from the World Health Organization. Social Science and Medicine 41(10)

    (1995), 1403-1409.

    The WHOQOL Group. The World Health Organization Quality of Life assessment (WHOQOL):

    development and general psychometric properties. Social Science and Medicine 46(12) (1998),

    1569-1585.

    World Health Organization, Constitution, WHO, Geneva, 1948.

    World Health Organization, Health for All Targets, WHO, Copenhagen, Denmark, 1984.

    World Health Organization, Summary report of the working group on concepts and principles of

    health promotion, Copehagen, 9-13 July 1984, The Journal of the Institute of Health Education

    23 1(1985), 5-9.

  • 175

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  • 185

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