from our filesBETAXOLOL: world first introduction of thiscardioselective P-blocker by Robert etCarriere in France

PharmacologyThe spectrofluorimetric estimation and buccal absorption of SL 75212, a

novel l3-adrenoceptor antagonist. Davis, Belinda J. and Turner, P.British Journal of Clinical Pharmacology 8: 405P (1979)

Pharmacokinetics of the new l3-adrenoceptor blocker SL 75212 in manafter repeated oral administration. Bianchetti, G. et a1. British Journalof Clinical Pharmacology 8: 408P (1979)

Comparison of the (3-adrenoceptor blocking properties andpharmacokinetics of SL 75212 and propranolol in man. Bianchetti, G.et al. British Journal of Clinical Pharmacology 8: 407P (1979)

Preliminary studies on SL 75212, a new potent cardioselective {3­

adrenoceptor antagonist. Boudot, J.P. et a1. British Journal ofPharmacology 66: 445P (1979)

Betaxolol hydrochloride. Cardioselective (3-adrenergic receptor blocker.Hillier, K. Drugs of the Future 4: 867 (1979)

Pharmacokinetics of SL 75212 propranolol in old age, uraemia and inhealthy young adults. Bianchetti, G. et a1. British Journal of ClinicalPharmacology 9: 299P (1980)

{3-Adrenoceptor blocking effects and pharmacokinetics of betaxolol (SL75212) in man. Giudicelli, J.E et al. British Journal of ClinicalPharmacology 10: 41 (1980)

Pharmacokinetics of the new {3-adrenoceptor blocking agent betaxolol (SL75212) in man after repeated oral administration. Bianchetti, G. et a1.Arzneimittel Forschung 30: 1912 (1980)

Blood concentrations and pharmacodynamic effects of betaxolol (SL75212) a new ,B-adrenoceptor antagonist after oral and intravenousadministration. Warrington, SJ. et a1. British Journal of ClinicalPharmacology 10: 449 (1980)

The duration of effect of SL75212 on an exercise tachycardia.Cardiovascular effects of single oral doses of the new l3-adrenoceptorblocking agent betaxolol (SL 75212) in healthy volunteers. Cadigan,PJ. et al. British Journal of Clinical Pharmacology 9: 569 (1980)Balnave, K. et a1. British Journal of Clinical Pharmacology 9: 297P(1980)

Betaxolol (SL 75212), a potent cardioselective l3-adrenoceptor antagonistwith interesting pharmacokinetic properties. Bianchetti, G. et a1.Federation Proceedings 39: 856 (1980)

I3-Adrenoceptor blocking effects and pharmacokinetics of betaxolol (SL75212) in man. Giudicelli, J.F. et a1. British Journal of ClinicalPharmacology to: 41 (1980)

Species variations in the kinetics of SL 75212, a new l3-adrenoceptorantagonist. Durand, A. et a1. British Journal of Pharmacology 69: 3tOP(1980)

Blood concentrations and pharmacodynamic effects of betaxolol (SL75212) a new (3-adrenoceptor antagonist after oral and intravenousadministration. Warrington, S.J. et al. British Journal of ClinicalPharmacology 10: 449 (1980)

Pharmacokinetics of, SL 75212 propranolol in old age, uraemia and inhealthy young adults. Bianchetti, G. et al. British Journal of ClinicalPharmacology 9: 299P (1980)

Observations on the efficacy and pharmacokinetics of betaxolol (SL75212), a cardioselective l3-adrenoceptor blocking drug. Balnave, K. eta1. British Journal of Clinical Pharmacology II: 171 (1981)

0156-2703/83/0723-0019/0$01.00/0 © ADIS Press

The haemoglobin-oxygen dissociation curve: In vivo and in vitro effects offive l3-adrenoceptor antagonists and lignocaine. Trembath, P.W. et al.British Journal of Clinical Pharmacology II: 19 (1981)

Influence of environmental temperature and humidity on bronchialresponses during assessment of selectivity of l3-adrenoceptorantagonists in man. Taylor, E.A. et al. British Journal of ClinicalPharmacology 12: 20 I (1981)

A comparison between propranolol, practolol and betaxolol (SL 75212) onthe circulatory and metabolic responses to insulin-inducedhypoglycaemia. Saunders, J. et al. European Journal of ClinicalPharmacology 21: 177 (1981)

Pharmacokinetics of betaxolol in hypertensive children. Assael, a.M. et al.Clinical Pharmacology and Therapeutics 29: 232 (1981)

Effect of Betaxolol on heart rate at rest and during exercise. Kesteloot Het al. Acta Cardiologica 37: 117 (1982) , .

Acute hemodynamic effect of betaxolol in uncomplicated essentialhypertension in young patients. Carre, A.G. et al. Archives desMaladies du Coeur et des Vaisseaux 75: 171-end of issue (1982)

Effect of betaxolol, a selective beta-blocker, on plasma lipids andlipoproteins. Jaillard, J. et al.Nouvelie Presse Medicale 11: 3206 (1982)

Betaxolol disposition in chronic renal insufficiency, hemodialysis andambulatory peritoneal dialysis. Bianchetti, G. et al.: European Journalof Clinical Investigation 12: 3 (1982)

Betaxolol hydrochloride. Anon. Drugs of the Future 7: 893 (I 982)Studies on the inhibition of vascular responses to endogenous

norepinephrine in spontaneously hypertensive rats pretreated withbetaxolol, A B - adrenoceptor antagonist. Cavero, I. FederationProceedings 42: 1018 (1983)

Betaxolol inhibits pressor responses to electrical stimulation of spinal cord,in spontaneously hypertensive rats. Cavero, I. British Journal ofPharmacology 78: 28P (1983)

Antihypertensive activity of betaxolol in conscious spontaneouslyhypertensive rats. Cavero, I. and Lefevre-Borg, F. British Journal ofPharmacology 78: l41P (1983)

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