AP217Tb-C AlphaPLEX 545 Human IFN-γ Tb (500 points)

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Kit components 04/03/2015 Product code Description AP217Tb-C AlphaPLEX 545 Human IFN-γ Tb (500 points) Components: AL217S AlphaLISA® human IFN-g (0.3 μg) AP217Tb-AHV AlphaPLEX 545 Anti-human IFN-γ Tb Acceptor Beads AL000C AlphaLISA® Assay Buffer (10 mL) 10X AL217BC AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 μL) 6760002 Streptavidin Donor Beads

Transcript of AP217Tb-C AlphaPLEX 545 Human IFN-γ Tb (500 points)

Kit components04/03/2015

Product code Description

AP217Tb-C AlphaPLEX 545 Human IFN-γ Tb (500 points)

Components:

AL217S AlphaLISA® human IFN-g (0.3 µg)

AP217Tb-AHV AlphaPLEX 545 Anti-human IFN-γ Tb Acceptor Beads

AL000C AlphaLISA® Assay Buffer (10 mL) 10X

AL217BC AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

6760002 Streptavidin Donor Beads

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Safety data sheetaccording to NOHSC 2003

Printing date 03.04.2015 Revision: 03.04.2015

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Not classified as hazardous according to criteria of Australian Safety and Compensation Council

1 Identification of the substance/mixture and of the company/undertaking

· Product identifier

· Trade name: AlphaLISA® human IFN-g (0.3 µg)

· Product number: AL217S· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:

PerkinElmer Inc549 Albany StBoston, MA 02118 USASupplier/Local:-------------------------------------------PerkinElmer AustraliaLvl 2, Bldg 5, Brandon Office Park530-540 Springvale RoadGlen WaverleyMelbourneVIC 3150Australia• Emergency telephone number:CHEMTREC (within US) 800-424-9300CHEMTREC (from outside US) 1(703)-527-3887• Local Emergency Number CHEMTREC - (Within Australia) +(61)-290372994

· Further information obtainable from:US Technical Support800-762-4000

2 Composition/information on ingredients

· Chemical characterisation: Mixtures· Description: Mixture of substances listed below with nonhazardous additions.

· Dangerous components:

77-86-1 TRIS 2.5-10%

2475-00-7 Proclin Acute Tox. 3, H301; Acute Tox. 3, H311; Skin Corr. 1B, H314; Eye Dam. 1, H318; Acute Tox. 4, H332; Skin Sens. 1, H317

<1.0%

· Additional Components

9004-54-0 Dextran 25-50%

7647-14-5 sodium chloride 2.5-10%

9048-46-8 Albumins, blood serum 1-2.5%

7732-18-5 Water 25-50%

· Additional information: Full text of R-, H- and EUH-phrases: see section 16

3 Hazards identification

· Classification of the substance or mixtureThe product is not classified according to the Globally Harmonised System (GHS).

(Contd. on page 2) AU

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· Additional information: For full text of H-statment and R-phrases: see SECTION 16

· Label elements· GHS label elements Void· Hazard pictograms Void· Signal word Void· Hazard statements Void

4 First aid measures

· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact: Immediately rinse with water.· After eye contact: Rinse opened eye for several minutes under running water.· After swallowing: If symptoms persist consult doctor.

5 Firefighting measures

· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required.· Environmental precautions: Do not allow to enter sewers/ surface or ground water.· Methods and material for containment and cleaning up: Pick up mechanically.· Reference to other sections

See Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

7 Handling and storage

· Precautions for safe handling Store in cool, dry place in tightly closed receptacles.· Information about fire - and explosion protection: No special measures required.· Storage:· Requirements to be met by storerooms and containers: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.· Ingredients with limit values that require monitoring at the workplace:

The product does not contain any relevant quantities of materials with critical values that have to be monitored atthe workplace.

· Personal protective equipment:· General protective and hygienic measures: Wash hands before breaks and at the end of work.

(Contd. on page 3) AU

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Safety data sheetaccording to NOHSC 2003

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Trade name: AlphaLISA® human IFN-g (0.3 µg)

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· Respiratory protection: Suitable respiratory protective device recommended.· Protection of hands:

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.

· Eye protection: Not required.

9 Physical and chemical properties

· General Information· Appearance:

Form: SolidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C

· Flash point: Not applicable.

· Flammability (solid, gaseous): Not determined.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density: Not determined.· Relative density Not determined.· Vapour density Not applicable.· Evaporation rate Not applicable.

· Solubility in / Miscibility withwater: Insoluble.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not applicable.Kinematic: Not applicable.

(Contd. on page 4) AU

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· Solvent content:Organic solvents: 0.0 %Water: 32.5 %

Solids content: 8.8 %· Other information No further relevant information available.

10 Stability and reactivity

· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information

· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritating effect.· Sensitisation: No sensitising effects known.

12 Ecological information

· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Bioaccumulative potential No further relevant information available.

13 Disposal considerations

· Waste treatment methods· Recommendation Must be specially treated adhering to official regulations.

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.

14 Transport information

· UN-Number· ADG, ADN, IMDG, IATA Void

· UN proper shipping name· ADG, ADN, IMDG, IATA Void

· Transport hazard class(es)

· ADG, ADN, IMDG, IATA· Class Void

(Contd. on page 5) AU

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· Packing group· ADG, IMDG, IATA Void

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Not applicable.

· Transport in bulk according to Annex II ofMARPOL73/78 and the IBC Code Not applicable.

· UN "Model Regulation": -

15 Regulatory information

· Australian Inventory of Chemical Substances

9004-54-0 Dextran

7647-14-5 sodium chloride

77-86-1 TRIS

9048-46-8 Albumins, blood serum

7647-01-0 hydrochloric acid

7732-18-5 Water

· Standard for the Uniform Scheduling of Medicines and Poisons

77-86-1 TRIS S4

7647-01-0 hydrochloric acid S5, S6

· GHS label elements Void· Hazard pictograms Void· Signal word Void· Hazard statements Void

16 Other informationThe information provided in this Material Safety Data Sheet is based on our present knowledge,and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be heldliable for any damage resulting from handling or from contact with the product.

· Relevant phrasesH301 Toxic if swallowed.H311 Toxic in contact with skin.H314 Causes severe skin burns and eye damage.H317 May cause an allergic skin reaction.H318 Causes serious eye damage.H332 Harmful if inhaled.

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationEINECS: European Inventory of Existing Commercial Chemical Substances

(Contd. on page 6) AU

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ELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)Acute Tox. 3: Acute toxicity, Hazard Category 3Acute Tox. 4: Acute toxicity, Hazard Category 4Skin Corr. 1B: Skin corrosion/irritation, Hazard Category 1BEye Dam. 1: Serious eye damage/eye irritation, Hazard Category 1Skin Sens. 1: Sensitisation - Skin, Hazard Category 1

AU

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Safety data sheetaccording to NOHSC 2003

Printing date 03.04.2015 Revision: 03.04.2015

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Hazardous according to criteria of Australian Safety and Compensation Council

1 Identification of the substance/mixture and of the company/undertaking

· Product identifier

· Trade name: AlphaPLEX 545 Anti-human IFN-γ Tb Acceptor Beads

· Product number: AP217Tb-AHV, AP217Tb-AC, AP217Tb-AF· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:

PerkinElmer Inc549 Albany StBoston, MA 02118 USASupplier/Local:-------------------------------------------PerkinElmer AustraliaLvl 2, Bldg 5, Brandon Office Park530-540 Springvale RoadGlen WaverleyMelbourneVIC 3150Australia• Emergency telephone number:CHEMTREC (within US) 800-424-9300CHEMTREC (from outside US) 1(703)-527-3887• Local Emergency Number CHEMTREC - (Within Australia) +(61)-290372994

· Further information obtainable from:US Technical Support800-762-4000

2 Composition/information on ingredients

· Chemical characterisation: Mixtures· Description: Mixture of substances listed below with nonhazardous additions.

· Dangerous components:

26172-55-4 5-chloro-2-methyl-2H-isothiazol-3-one Acute Tox. 3, H301; Acute Tox. 3, H311; Acute Tox. 3, H331; Skin Corr. 1B,

H314; Skin Sens. 1, H317

<0.1%

· Additional Components

7732-18-5 Water 75-100%

· Additional information: Full text of R-, H- and EUH-phrases: see section 16

3 Hazards identification

· Classification of the substance or mixture

Skin Irrit. 2 H315 Causes skin irritation.

Eye Irrit. 2 H319 Causes serious eye irritation.

Skin Sens. 1 H317 May cause an allergic skin reaction.· Additional information: For full text of H-statment and R-phrases: see SECTION 16

(Contd. on page 2) AU

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· Label elements· GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS).· Hazard pictograms

GHS07

· Signal word Warning

· Hazard-determining components of labelling:5-chloro-2-methyl-2H-isothiazol-3-one

· Hazard statementsCauses skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.

· Precautionary statementsAvoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.Take off contaminated clothing and wash before reuse.Wash contaminated clothing before reuse.Dispose of contents/container in accordance with local/regional/national/international regulations.

4 First aid measures

· After inhalation:Supply fresh air and to be sure call for a doctor.In case of unconsciousness place patient stably in side position for transportation.

· After eye contact:Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.

· After swallowing: If symptoms persist consult doctor.

5 Firefighting measures

· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required.· Environmental precautions: Do not allow to enter sewers/ surface or ground water.· Methods and material for containment and cleaning up:

Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).Ensure adequate ventilation.

· Reference to other sectionsSee Section 7 for information on safe handling.

(Contd. on page 3) AU

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See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

7 Handling and storage

· Precautions for safe handlingEnsure good ventilation/exhaustion at the workplace.Prevent formation of aerosols.

· Information about fire - and explosion protection: No special measures required.· Storage:· Requirements to be met by storerooms and containers: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: Keep container tightly sealed.· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.· Ingredients with limit values that require monitoring at the workplace:

The product does not contain any relevant quantities of materials with critical values that have to be monitored atthe workplace.

· Personal protective equipment:· General protective and hygienic measures:

Keep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.Avoid contact with the eyes and skin.

· Respiratory protection:In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure useself-contained respiratory protective device.Suitable respiratory protective device recommended.

· Protection of hands:

Protective gloves

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.

(Contd. on page 4) AU

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Trade name: AlphaPLEX 545 Anti-human IFN-γ Tb Acceptor Beads

(Contd. of page 3)

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· Eye protection:

Tightly sealed goggles

9 Physical and chemical properties

· General Information· Appearance:

Form: FluidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C

· Flash point: Not applicable.

· Flammability (solid, gaseous): Not applicable.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density: Not determined.· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withwater: Not miscible or difficult to mix.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not determined.Kinematic: Not determined.

· Solvent content:Organic solvents: 0.0 %Water: 99.0 %

· Other information No further relevant information available.

AU

(Contd. on page 5)

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10 Stability and reactivity

· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information

· Acute toxicity:· Primary irritant effect:· on the skin: Irritant to skin and mucous membranes.· on the eye: Irritating effect.· Sensitisation: Sensitisation possible through skin contact.· Additional toxicological information:

The product shows the following dangers according to the calculation method of the General EU ClassificationGuidelines for Preparations as issued in the latest version:Irritant

12 Ecological information

· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Bioaccumulative potential No further relevant information available.

13 Disposal considerations

· Waste treatment methods· Recommendation Must be specially treated adhering to official regulations.

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.

14 Transport information

· UN-Number· ADG, IMDG, IATA UN1760

· UN proper shipping name· ADG 1760 CORROSIVE LIQUID, N.O.S. (5-chloro-2-methyl-2H-

isothiazol-3-one)· IMDG, IATA CORROSIVE LIQUID, N.O.S. (5-chloro-2-methyl-2H-isothiazol-3-

one)

(Contd. on page 6) AU

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· Transport hazard class(es)

· ADG, IMDG, IATA

· Class 8 Corrosive substances.· Label 8

· Packing group· ADG, IMDG, IATA III

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Warning: Corrosive substances.· Danger code (Kemler): 80· EMS Number: F-A,S-B

· Transport in bulk according to Annex II ofMARPOL73/78 and the IBC Code Not applicable.

· Transport/Additional information:

· ADG· Limited quantities (LQ) 5L· Excepted quantities (EQ) Code: E1

Maximum net quantity per inner packaging: 30 mlMaximum net quantity per outer packaging: 1000 ml

· Transport category 3 · Tunnel restriction code E

· IMDG· Limited quantities (LQ) 5L· Excepted quantities (EQ) Code: E1

Maximum net quantity per inner packaging: 30 mlMaximum net quantity per outer packaging: 1000 ml

· UN "Model Regulation": UN1760, CORROSIVE LIQUID, N.O.S. (5-chloro-2-methyl-2H-isothiazol-3-one), 8, III

15 Regulatory information

· Australian Inventory of Chemical Substances

26172-55-4 5-chloro-2-methyl-2H-isothiazol-3-one

7558-79-4 disodium hydrogenorthophosphate

7778-77-0 potassium dihydrogenorthophosphate

7447-40-7 potassium chloride

7647-14-5 sodium chloride

7732-18-5 Water

· Standard for the Uniform Scheduling of Medicines and Poisons

7447-40-7 potassium chloride S4

· GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS).(Contd. on page 7)

AU

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· Hazard pictograms

GHS07

· Signal word Warning

· Hazard-determining components of labelling:5-chloro-2-methyl-2H-isothiazol-3-one

· Hazard statementsCauses skin irritation.Causes serious eye irritation.May cause an allergic skin reaction.

· Precautionary statementsAvoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.Take off contaminated clothing and wash before reuse.Wash contaminated clothing before reuse.Dispose of contents/container in accordance with local/regional/national/international regulations.

16 Other informationThe information provided in this Material Safety Data Sheet is based on our present knowledge,and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be heldliable for any damage resulting from handling or from contact with the product.

· Relevant phrasesH301 Toxic if swallowed.H311 Toxic in contact with skin.H314 Causes severe skin burns and eye damage.H317 May cause an allergic skin reaction.H331 Toxic if inhaled.

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)Acute Tox. 3: Acute toxicity, Hazard Category 3Skin Corr. 1B: Skin corrosion/irritation, Hazard Category 1BSkin Irrit. 2: Skin corrosion/irritation, Hazard Category 2Eye Irrit. 2: Serious eye damage/eye irritation, Hazard Category 2Skin Sens. 1: Sensitisation - Skin, Hazard Category 1

AU

Page 1/7

Safety data sheetaccording to NOHSC 2003

Printing date 03.04.2015 Revision: 03.04.2015

40.0

Hazardous according to criteria of Australian Safety and Compensation Council

1 Identification of the substance/mixture and of the company/undertaking

· Product identifier

· Trade name: AlphaLISA® Assay Buffer (10 mL) 10X

· Product number: AL000C· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:

PerkinElmer Inc549 Albany StBoston, MA 02118 USASupplier/Local:-------------------------------------------PerkinElmer AustraliaLvl 2, Bldg 5, Brandon Office Park530-540 Springvale RoadGlen WaverleyMelbourneVIC 3150Australia• Emergency telephone number:CHEMTREC (within US) 800-424-9300CHEMTREC (from outside US) 1(703)-527-3887• Local Emergency Number CHEMTREC - (Within Australia) +(61)-290372994

· Further information obtainable from:US Technical Support800-762-4000

2 Composition/information on ingredients

· Chemical characterisation: Mixtures· Description: Mixture of substances listed below with nonhazardous additions.

· Dangerous components:

9002-93-1 Polyethylene glycol octylphenol ether Eye Irrit. 2, H319 2.5-10%

· Additional Components

7365-45-9 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonic acid 2.5-10%

75277-39-3 sodium 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonate 1-2.5%

9000-71-9 casein 1-2.5%

9004-54-0 Dextran 1-2.5%

7732-18-5 Water 75-100%

· SVHC

9002-93-1 Polyethylene glycol octylphenol ether

· Additional information: Full text of R-, H- and EUH-phrases: see section 16 AU

(Contd. on page 2)

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3 Hazards identification

· Classification of the substance or mixture

Eye Dam. 1 H318 Causes serious eye damage.

Acute Tox. 4 H302 Harmful if swallowed.· Additional information: For full text of H-statment and R-phrases: see SECTION 16

· Label elements· GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS).· Hazard pictograms

GHS05 GHS07

· Signal word Danger· Hazard statements

Harmful if swallowed.Causes serious eye damage.

· Precautionary statementsWear protective gloves/protective clothing/eye protection/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.Immediately call a POISON CENTER/doctor.IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.Dispose of contents/container in accordance with local/regional/national/international regulations.

4 First aid measures

· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact: Immediately rinse with water.· After eye contact: Rinse opened eye for several minutes under running water.· After swallowing: If symptoms persist consult doctor.

5 Firefighting measures

· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required.· Environmental precautions:

Inform respective authorities in case of seepage into water course or sewage system.Do not allow to enter sewers/ surface or ground water.

· Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).

(Contd. on page 3) AU

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Trade name: AlphaLISA® Assay Buffer (10 mL) 10X

(Contd. of page 2)

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· Reference to other sectionsSee Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

7 Handling and storage

· Precautions for safe handling Store in cool, dry place in tightly closed receptacles.· Information about fire - and explosion protection: No special measures required.· Storage:· Requirements to be met by storerooms and containers: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.· Ingredients with limit values that require monitoring at the workplace:

The product does not contain any relevant quantities of materials with critical values that have to be monitored atthe workplace.

· Personal protective equipment:· General protective and hygienic measures: Wash hands before breaks and at the end of work.· Respiratory protection: Suitable respiratory protective device recommended.· Protection of hands:

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.

· Eye protection: Goggles recommended during refilling

9 Physical and chemical properties

· General Information· Appearance:

Form: FluidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C

· Flash point: Not applicable.

(Contd. on page 4) AU

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(Contd. of page 3)

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· Flammability (solid, gaseous): Not applicable.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density: Not determined.· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withwater: Not miscible or difficult to mix.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not determined.Kinematic: Not determined.

· Solvent content:Organic solvents: 0.0 %Water: 85.4 %

Solids content: 1.0 %· Other information No further relevant information available.

10 Stability and reactivity

· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information

· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritating effect.· Sensitisation: No sensitising effects known.

12 Ecological information

· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Bioaccumulative potential No further relevant information available.

(Contd. on page 5) AU

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· Ecotoxical effects:· Remark: Harmful to fish

13 Disposal considerations

· Waste treatment methods· Recommendation Must be specially treated adhering to official regulations.

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.

14 Transport information

· UN-Number· ADG, ADN, IATA Void· IMDG UN3082

· UN proper shipping name· ADG, ADN, IATA Void· IMDG ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,

N.O.S. (Polyethylene glycol octylphenol ether), MARINEPOLLUTANT

· Transport hazard class(es)

· ADG, ADN, IATA· Class Void

· IMDG

· Class 9 Miscellaneous dangerous substances and articles.· Label 9

· Packing group· ADG, IATA Void· IMDG III

· Environmental hazards: Product contains environmentally hazardous substances:Polyethylene glycol octylphenol ether

· Marine pollutant: YesSymbol (fish and tree)

· Special precautions for user Not applicable.· EMS Number: F-A,S-F

· Transport in bulk according to Annex II ofMARPOL73/78 and the IBC Code Not applicable.

(Contd. on page 6) AU

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· Transport/Additional information:

· IMDG· Limited quantities (LQ) 5L· Excepted quantities (EQ) Code: E1

Maximum net quantity per inner packaging: 30 mlMaximum net quantity per outer packaging: 1000 ml

· UN "Model Regulation": -

15 Regulatory information

· Australian Inventory of Chemical Substances

All ingredients are listed.

· Standard for the Uniform Scheduling of Medicines and Poisons

77-86-1 TRIS S4

· GHS label elements The product is classified and labelled according to the Globally Harmonised System (GHS).· Hazard pictograms

GHS05 GHS07

· Signal word Danger· Hazard statements

Harmful if swallowed.Causes serious eye damage.

· Precautionary statementsWear protective gloves/protective clothing/eye protection/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.Continue rinsing.Immediately call a POISON CENTER/doctor.IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.Dispose of contents/container in accordance with local/regional/national/international regulations.

16 Other informationThe information provided in this Material Safety Data Sheet is based on our present knowledge,and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be heldliable for any damage resulting from handling or from contact with the product.

· Relevant phrasesH319 Causes serious eye irritation.

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous Goods

(Contd. on page 7) AU

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(Contd. of page 6)

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IATA: International Air Transport AssociationEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)Acute Tox. 4: Acute toxicity, Hazard Category 4Eye Dam. 1: Serious eye damage/eye irritation, Hazard Category 1Eye Irrit. 2: Serious eye damage/eye irritation, Hazard Category 2

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Not classified as hazardous according to criteria of Australian Safety and Compensation Council

1 Identification of the substance/mixture and of the company/undertaking

· Product identifier

· Trade name: AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

· Product number: AL217BC· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:

PerkinElmer Inc549 Albany StBoston, MA 02118 USASupplier/Local:-------------------------------------------PerkinElmer AustraliaLvl 2, Bldg 5, Brandon Office Park530-540 Springvale RoadGlen WaverleyMelbourneVIC 3150Australia• Emergency telephone number:CHEMTREC (within US) 800-424-9300CHEMTREC (from outside US) 1(703)-527-3887• Local Emergency Number CHEMTREC - (Within Australia) +(61)-290372994

· Further information obtainable from:US Technical Support800-762-4000

2 Composition/information on ingredients

· Chemical characterisation: Mixtures· Description: Mixture of substances listed below with nonhazardous additions.

· Dangerous components:

75-05-8 acetonitrile Flam. Liq. 2, H225; Acute Tox. 4, H302; Acute Tox. 4, H312; Acute Tox. 4, H332; Eye

Irrit. 2, H319

1-2.5%

· Additional Components

57-50-1 sucrose, pure 2.5-10%

7732-18-5 Water 75-100%

3 Hazards identification

· Classification of the substance or mixtureThe product is not classified according to the Globally Harmonised System (GHS).

· Label elements· GHS label elements Void· Hazard pictograms Void

(Contd. on page 2) AU

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(Contd. of page 1)

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· Signal word Void

· Hazard-determining components of labelling:acetonitrile

· Hazard statements Void

4 First aid measures

· General information: No special measures required.· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact: If skin irritation continues, consult a doctor.· After eye contact: Rinse opened eye for several minutes under running water.· After swallowing: If symptoms persist consult doctor.

5 Firefighting measures

· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required.· Environmental precautions: No special measures required.· Methods and material for containment and cleaning up:

Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).· Reference to other sections

See Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

7 Handling and storage

· Precautions for safe handling No special measures required.· Information about fire - and explosion protection: No special measures required.· Storage:· Requirements to be met by storerooms and containers: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.

· Ingredients with limit values that require monitoring at the workplace:

57-50-1 sucrose, pure (2.5-10%)

NES Long-term value: 10 mg/m³(Contd. on page 3)

AU

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Trade name: AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

(Contd. of page 2)

40.0

75-05-8 acetonitrile (1-2.5%)

NES Short-term value: 101 mg/m³, 60 ppmLong-term value: 67 mg/m³, 40 ppmSk

· Personal protective equipment:· General protective and hygienic measures:

The usual precautionary measures are to be adhered to when handling chemicals.· Respiratory protection: Not required.· Protection of hands:

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.

· Eye protection: Goggles recommended during refilling

9 Physical and chemical properties

· General Information· Appearance:

Form: FluidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C

· Flash point: Not applicable.

· Flammability (solid, gaseous): Not applicable.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density: Not determined.· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.

(Contd. on page 4) AU

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Trade name: AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

(Contd. of page 3)

40.0

· Solubility in / Miscibility withwater: Not miscible or difficult to mix.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not determined.Kinematic: Not determined.

· Solvent content:Organic solvents: 0.2 %Water: 90.9 %

· Other information No further relevant information available.

10 Stability and reactivity

· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information

· Acute toxicity:

· LD/LC50 values relevant for classification:

26628-22-8 sodium azide

Oral LD50 27 mg/kg (rat)

Dermal LD50 20 mg/kg (rabbit)

· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritating effect.· Sensitisation: No sensitising effects known.· Additional toxicological information:

The product is not subject to classification according to the calculation method of the General EU ClassificationGuidelines for Preparations as issued in the latest version.When used and handled according to specifications, the product does not have any harmful effects to ourexperience and the information provided to us.

12 Ecological information

· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Bioaccumulative potential No further relevant information available.

13 Disposal considerations

· Waste treatment methods· Recommendation Must be specially treated adhering to official regulations.

(Contd. on page 5) AU

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Safety data sheetaccording to NOHSC 2003

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Trade name: AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

(Contd. of page 4)

40.0

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.

14 Transport information

· UN-Number· ADG, ADN, IMDG, IATA Void

· UN proper shipping name· ADG, ADN, IMDG, IATA Void

· Transport hazard class(es)

· ADG, ADN, IMDG, IATA· Class Void

· Packing group· ADG, IMDG, IATA Void

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Not applicable.

· Transport in bulk according to Annex II ofMARPOL73/78 and the IBC Code Not applicable.

· UN "Model Regulation": -

15 Regulatory information

· Australian Inventory of Chemical Substances

57-50-1 sucrose, pure

75-05-8 acetonitrile

50-81-7 ascorbic acid

9048-46-8 Albumins, blood serum

64-19-7 acetic acid

9005-64-5 TWEEN 20

26628-22-8 sodium azide

7732-18-5 Water

· Standard for the Uniform Scheduling of Medicines and Poisons

64-19-7 acetic acid S2, S5, S6

· GHS label elements Void· Hazard pictograms Void· Signal word Void

· Hazard-determining components of labelling:acetonitrile

· Hazard statements Void AU

(Contd. on page 6)

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Trade name: AlphaLISA® Biotinylated Antibody Anti-IFN-g (50 µL)

(Contd. of page 5)

40.0

16 Other informationThe information provided in this Material Safety Data Sheet is based on our present knowledge,and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be heldliable for any damage resulting from handling or from contact with the product.

· Relevant phrasesH225 Highly flammable liquid and vapour.H302 Harmful if swallowed.H312 Harmful in contact with skin.H319 Causes serious eye irritation.H332 Harmful if inhaled.

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)LC50: Lethal concentration, 50 percentLD50: Lethal dose, 50 percentFlam. Liq. 2: Flammable liquids, Hazard Category 2Acute Tox. 4: Acute toxicity, Hazard Category 4Eye Irrit. 2: Serious eye damage/eye irritation, Hazard Category 2

AU

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Not classified as hazardous according to criteria of Australian Safety and Compensation Council

1 Identification of the substance/mixture and of the company/undertaking

· Product identifier

· Trade name: Streptavidin Donor Beads

· Product number: 6760002· Application of the substance / the mixture Laboratory chemicals

· Details of the supplier of the safety data sheet· Manufacturer/Supplier:

PerkinElmer Inc549 Albany StBoston, MA 02118 USASupplier/Local:-------------------------------------------PerkinElmer AustraliaLvl 2, Bldg 5, Brandon Office Park530-540 Springvale RoadGlen WaverleyMelbourneVIC 3150Australia• Emergency telephone number:CHEMTREC (within US) 800-424-9300CHEMTREC (from outside US) 1(703)-527-3887• Local Emergency Number CHEMTREC - (Within Australia) +(61)-290372994

· Further information obtainable from:US Technical Support800-762-4000

2 Composition/information on ingredients

· Chemical characterisation: Mixtures· Description: Mixture of substances listed below with nonhazardous additions.

· Dangerous components: Void

· Additional Components

7732-18-5 Water 75-100%

3 Hazards identification

· Classification of the substance or mixtureThe product is not classified according to the Globally Harmonised System (GHS).

· Label elements· GHS label elements Void· Hazard pictograms Void· Signal word Void· Hazard statements Void

AU

(Contd. on page 2)

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Trade name: Streptavidin Donor Beads

(Contd. of page 1)

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4 First aid measures

· General information: No special measures required.· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact: If skin irritation continues, consult a doctor.· After eye contact: Rinse opened eye for several minutes under running water.· After swallowing: If symptoms persist consult doctor.

5 Firefighting measures

· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· Special hazards arising from the substance or mixture No further relevant information available.· Protective equipment: Wear self-contained respiratory protective device.

6 Accidental release measures

· Personal precautions, protective equipment and emergency procedures Not required.· Environmental precautions: No special measures required.· Methods and material for containment and cleaning up:

Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).· Reference to other sections

See Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

7 Handling and storage

· Precautions for safe handling No special measures required.· Information about fire - and explosion protection: No special measures required.· Storage:· Requirements to be met by storerooms and containers: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· Specific end use(s) No further relevant information available.

8 Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.· Ingredients with limit values that require monitoring at the workplace:

The product does not contain any relevant quantities of materials with critical values that have to be monitored atthe workplace.

· Personal protective equipment:· General protective and hygienic measures:

The usual precautionary measures are to be adhered to when handling chemicals.· Respiratory protection: Not required.· Protection of hands:

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

(Contd. on page 3) AU

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Trade name: Streptavidin Donor Beads

(Contd. of page 2)

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· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of quality andvaries from manufacturer to manufacturer. As the product is a preparation of several substances, the resistanceof the glove material can not be calculated in advance and has therefore to be checked prior to the application.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.

· Eye protection: Goggles recommended during refilling

9 Physical and chemical properties

· General Information· Appearance:

Form: FluidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C

· Flash point: Not applicable.

· Flammability (solid, gaseous): Not applicable.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density: Not determined.· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withwater: Not miscible or difficult to mix.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not determined.Kinematic: Not determined.

· Solvent content:Organic solvents: 0.0 %Water: 98.2 %

Solids content: 0.6 %

(Contd. on page 4) AU

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(Contd. of page 3)

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· Other information No further relevant information available.

10 Stability and reactivity

· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· Incompatible materials: No further relevant information available.· Hazardous decomposition products: No dangerous decomposition products known.

11 Toxicological information

· Acute toxicity:· Primary irritant effect:· on the skin: No irritant effect.· on the eye: No irritating effect.· Sensitisation: No sensitising effects known.· Additional toxicological information:

The product is not subject to classification according to the calculation method of the General EU ClassificationGuidelines for Preparations as issued in the latest version.When used and handled according to specifications, the product does not have any harmful effects to ourexperience and the information provided to us.

12 Ecological information

· Aquatic toxicity: No further relevant information available.· Persistence and degradability No further relevant information available.· Bioaccumulative potential No further relevant information available.

13 Disposal considerations

· Waste treatment methods· Recommendation Must be specially treated adhering to official regulations.

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.

14 Transport information

· UN-Number· ADG, ADN, IMDG, IATA Void

· UN proper shipping name· ADG, ADN, IMDG, IATA Void

· Transport hazard class(es)

· ADG, ADN, IMDG, IATA· Class Void

(Contd. on page 5) AU

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(Contd. of page 4)

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· Packing group· ADG, IMDG, IATA Void

· Environmental hazards:· Marine pollutant: No

· Special precautions for user Not applicable.

· Transport in bulk according to Annex II ofMARPOL73/78 and the IBC Code Not applicable.

· UN "Model Regulation": -

15 Regulatory information

· Australian Inventory of Chemical Substances

7365-45-9 4-(2-hydroxyethyl)piperazin-1-ylethanesulphonic acid

7647-14-5 sodium chloride

9003-53-6 POLYSTYRENE

7732-18-5 Water

· Standard for the Uniform Scheduling of Medicines and Poisons

None of the ingredients is listed.

· GHS label elements Void· Hazard pictograms Void· Signal word Void· Hazard statements Void

16 Other informationThe information provided in this Material Safety Data Sheet is based on our present knowledge,and believed to be correct at the date of publication. However, no representation is madeconcerning its accuracy and completeness. It is intended as guidance only, and is not to beconsidered a warranty or quality specification. All materials may present unknown hazards, andshould be used with caution. Although certain hazards are described, we cannot guarantee thatthese are the only hazards which exist. PerkinElmer, Inc. shall not be heldliable for any damage resulting from handling or from contact with the product.

· Abbreviations and acronyms:ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)

AU