The VAMI project recent publications (1/2012-8/2014) Pepe A, Zhao L, Koikkalainen J, Hietala J, Ruotsalainen U, Tohka J. Automatic statistical shape analysis of cerebral asymmetry in 3D T1-weighted magnetic resonance images at vertex-level: application to neuroleptic-naïve schizophrenia. Magn Reson Imaging. 2013 Jun;31(5):676-87. Delvecchio G, Fossati P, Boyer P, Brambilla P, Falkai P, Gruber O, Hietala J, Lawrie SM, Martinot JL, McIntosh AM, Meisenzahl E, Frangou S. Common and distinct neural correlates of emotional processing in Bipolar Disorder and Major Depressive Disorder: a voxel-based meta-analysis of functional magnetic resonance imaging studies. Eur Neuropsychopharmacol. 2012 Feb;22(2):100-13.. Dragt S, Nieman DH, Schultze-Lutter F, van der Meer F, Becker H, de Haan L, Dingemans PM, Birchwood M, Patterson P, Salokangas RK, Heinimaa M, Heinz A, Juckel G, Graf von Reventlow H, French P, Stevens H, Ruhrmann S, Klosterkötter J, Linszen DH; EPOS group. Cannabis use and age at onset of symptoms in subjects at clinical high risk for psychosis. Acta Psychiatr Scand. 2012 Jan;125(1):45-53. Miles SW, Sheridan J, Russell B, Kydd R, Wheeler A, Walters C, Gamble G, Hardley P, Jensen M, Kuoppasalmi K, Tuomola P, Föhr J, Kuikanmäki O, Vorma H, Salokangas R, Mikkonen A, Kallio M, Kauhanen J, Kiviniemi V, Tiihonen J. Extended-release methylphenidate for treatment of amphetamine/methamphetamine dependence: a randomized, double-blind, placebo-controlled trial. Addiction. 2013 Jul;108(7):1279-86. Hagelberg N, Aalto S, Tuominen L, Pesonen U, Någren K, Hietala J, Scheinin H, Pertovaara A, Martikainen IK. Striatal μ-opioid receptor availability predicts cold pressor pain threshold in healthy human subjects. Neurosci Lett. 2012 Jul 11;521(1):11-4. Salokangas RK, Salminen JK, Korpelainen J, Helenius H, Korkeila J. Increased use of antidepressants in women decreases suicides in men: an ecological study. Prim Care Companion CNS Disord. 2012;14(3). Jääskeläinen SK, Lindholm P, Valmunen T, Pesonen U, Taiminen T, Virtanen A, Lamusuo S, Forssell H, Hagelberg N, Hietala J, Pertovaara A. Variation in the dopamine D2 receptor gene plays a key role in human pain and its modulation by transcranial magnetic stimulation. Pain. 2014 Aug 29. pii: S0304-3959(14)00388-1. doi: 10.1016/j.pain.2014.08.029. [Epub ahead of print] Joutsa J, Johansson J, Niemelä S, Ollikainen A, Hirvonen MM, Piepponen P, Arponen E, Alho H, Voon V, Rinne JO, Hietala J, Kaasinen V.Mesolimbic dopamine

release is linked to symptom severity in pathological gambling. Neuroimage. 2012 May 1;60(4):1992-9 Karlsson H, Hirvonen J, Salminen J, Hietala J. Increased serotonin receptor 1A binding in major depressive disorder after psychotherapy, but not after SSRI pharmacotherapy, is related to improved social functioning capacity. Psychother Psychosom. 2013;82(4):260-1. Karlsson L, Tuominen L, Huotarinen A, Leppämäki S, Sihvola E, Helin S, Sipilä M, Tani P, Hirvonen J, Hietala J, Karlsson H. Serotonin transporter in attention-deficit hyperactivity disorder--preliminary results from a positron emission tomography study.Psychiatry Res. 2013 May 30;212(2):164-5. Korkeila J, Salokangas RK, Heinimaaa M, Svirskis T, Laine T, Ruhrmann S, von Reventlow H, Juckel G, Linszen D, Birchwood M, Klosterkötter J; EPOS Group. Physical illnesses, developmental risk factors and psychiatric diagnoses among subjects at risk of psychosis. Eur Psychiatry. 2013 Mar;28(3):135-40. Michelson D, Hargreaves R, Alexander R, Ceesay P, Hietala J, Lines C, Reines S. Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder. Int J Neuropsychopharmacol. 2013 Feb;16(1):1-11. Luutonen S, Tikka M, Karlsson H, Salokangas RK. Childhood trauma and distress experiences associate with psychotic symptoms in patients attending primary and psychiatric outpatient care. Results of the RADEP study. Eur Psychiatry. 2013 Mar;28(3):154-60. Nieman DH, Velthorst E, Becker HE, de Haan L, Dingemans PM, Linszen DH, Birchwood M, Patterson P, Salokangas RK, Heinimaa M, Heinz A, Juckel G, von Reventlow HG, Morrison A, Schultze-Lutter F, Klosterkötter J, Ruhrmann S; EPOS group. The Strauss and Carpenter Prognostic Scale in subjects clinically at high risk of psychosis. Acta Psychiatr Scand. 2013 Jan;127(1):53-61. Salokangas RK, Dingemans P, Heinimaa M, Svirskis T, Luutonen S, Hietala J, Ruhrmann S, Juckel G, Graf von Reventlow H, Linszen D, Birchwood M, Patterson P, Schultze-Lutter F, Klosterkötter J; EPOS group. Prediction of psychosis in clinical high-risk patients by the Schizotypal Personality Questionnaire. Results of the EPOS project. Eur Psychiatry. 2013 Oct;28(8):469-75. Salokangas RK, Heinimaa M, From T, Löyttyniemi E, Ilonen T, Luutonen S, Hietala J, Svirskis T, von Reventlow HG, Juckel G, Linszen D, Dingemans P, Birchwood M, Patterson P, Schultze-Lutter F, Ruhrmann S, Klosterkötter J; EPOS group. Short-term functional outcome and premorbid adjustment in clinical high-risk patients. Results of the EPOS project. Eur Psychiatry. 2014 Aug;29(6):371-80. Salokangas RK, Heinimaa M, Sillanmäki L, Sourander A. Self-reported experiences as predictors for onset of psychotropic medication. A prospective study of healthy draftees. Nord J Psychiatry. 2013 Oct;67(5):298-304.

Salokangas RK, Nieman DH, Heinimaa M, Svirskis T, Luutonen S, From T, von Reventlow HG, Juckel G, Linszen D, Dingemans P, Birchwood M, Patterson P, Schultze-Lutter F, Klosterkötter J, Ruhrmann S; EPOS group. Psychosocial outcome in patients at clinical high risk of psychosis: a prospective follow-up. Soc Psychiatry Psychiatr Epidemiol. 2013 Feb;48(2):303-11. Salokangas RK, Patterson P, Heinimaa M, Svirskis T, From T, Vaskelainen L, Klosterkötter J, Ruhrmann S, von Reventlow HG, Juckel G, Linszen D, Dingemans P, Birchwood M; EPOS Group. Perceived negative attitude of others predicts transition to psychosis in patients at risk of psychosis. Eur Psychiatry. 2012 May;27(4):264-6. Salokangas RK, Ruhrmann S, von Reventlow HG, Heinimaa M, Svirskis T, From T, Luutonen S, Juckel G, Linszen D, Dingemans P, Birchwood M, Patterson P, Schultze-Lutter F, Klosterkötter J; EPOS group. Axis I diagnoses and transition to psychosis in clinical high-risk patients EPOS project: prospective follow-up of 245 clinical high-risk outpatients in four countries. Schizophr Res. 2012 Jul;138(2-3):192-7. Salokangas RK, Tuominen L, Koponen H, Laukkala T, Oksanen J, Pirkola S, Saxen U.Duodecim. 2013;129(8):846-7. [Update on current care guidelines: schizophrenia]. Tikka M, Luutonen S, Ilonen T, Tuominen L, Kotimäki M, Hankala J, Salokangas RK. Childhood trauma and premorbid adjustment among individuals at clinical high risk for psychosis and normal control subjects. Early Interv Psychiatry. 2013 Feb;7(1):51-7 Tuominen L, Nummenmaa L, Keltikangas-Järvinen L, Raitakari O, Hietala J. Mapping neurotransmitter networks with PET: an example on serotonin and opioid systems. Hum Brain Mapp. 2014 May;35(5):1875-84. Tuominen L, Salo J, Hirvonen J, Någren K, Laine P, Melartin T, Isometsä E, Viikari J, Cloninger CR, Raitakari O, Hietala J, Keltikangas-Järvinen L. Temperament, character and serotonin activity in the human brain: a positron emission tomography study based on a general population cohort. Psychol Med. 2013 Apr;43(4):881-94. Tuominen L, Salo J, Hirvonen J, Någren K, Laine P, Melartin T, Isometsä E, Viikari J, Raitakari O, Keltikangas-Järvinen L, Hietala J. Temperament trait Harm Avoidance associates with μ-opioid receptor availability in frontal cortex: a PET study using [(11)C]carfentanil. Neuroimage. 2012 Jul 2;61(3):670-6. von Reventlow HG, Krüger-Özgürdal S, Ruhrmann S, Schultze-Lutter F, Heinz A, Patterson P, Heinimaa M, Dingemans P, French P, Birchwood M, Salokangas RK, Linszen D, Morrison A, Klosterkötter J, Juckel G. Pathways to care in subjects at high risk for psychotic disorders - a European perspective. Schizophr Res. 2014 Feb;152(2-3):400-7.

Yung AR, Woods SW, Ruhrmann S, Addington J, Schultze-Lutter F, Cornblatt BA, Amminger GP, Bechdolf A, Birchwood M, Borgwardt S, Cannon TD, de Haan L, French P, Fusar-Poli P, Keshavan M, Klosterkötter J, Kwon JS, McGorry PD, McGuire P, Mizuno M, Morrison AP, Riecher-Rössler A, Salokangas RK, Seidman LJ, Suzuki M, Valmaggia L, van der Gaag M, Wood SJ, McGlashan TH. Whither the attenuated psychosis syndrome? Schizophr Bull. 2012 Nov;38(6):1130-4.