maybe isatoic anhydride will be your "magic"

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maybe isatoic anhydride will be your "magic" molecule, 9 too ο II .C=0 IA is a most versatile ^^^^^^>N molecule... ^^ I its "ring" is easily opened Η by reactions with a variety of active hydrogen compounds to form Anthranilic Acid derivatives. These deriva- tives are convenient, low-cost intermediates for a variety of heterocyclic compounds. IA is the key to many ortho-substituted aro- matics and the "magic" molecule for the formation of a vast number of heterocyclic systems. Another intriguing aspect of IA (or the derived Anthranilic Acid) is the generation of benzyne via anhydrous diazotization in an aprotic solvent. Technical literature and samples are available. Also, ask about N-Methylisatoic Anhydride and 5-Nitroisatoic Anhydride. For technical literature write: ^hpfwin L. R. Burkardt, SHERWIN \A iMarnQ WILLIAMS CHEMICALS, P. O. ^!™>olr Box 6520, Cleveland, Ohio CnemiCdlS 44101. CIRCLE 26 ON READER SERVICE CARD

Transcript of maybe isatoic anhydride will be your "magic"

maybe isatoic anhydride will be your "magic" molecule, 9 too ο II

.C=0 IA is a most versatile ^ ^ ^ ^ ^ ^ > N molecule. . . ^ ^ I its "r ing" is easily opened Η by reactions with a variety of active hydrogen compounds to form Anthranilic Acid derivatives. These deriva­tives are convenient, low-cost intermediates for a variety of heterocyclic compounds.

IA is the key to many ortho-substituted aro-matics and the "magic" molecule for the formation of a vast number of heterocyclic systems.

Another intriguing aspect of IA (or the derived Anthranilic Acid) is the generation of benzyne via anhydrous diazotization in an aprotic solvent.

Technical literature and samples are available. Also, ask about N-Methylisatoic Anhydride and 5-Nitroisatoic Anhydride.

For technical literature write: ^hpfwin L. R. Burkardt , SHERWIN \A iMarnQ WILLIAMS CHEMICALS, P. O. ^ ! ™ > o l r Box 6520, Cleveland, Ohio CnemiCdlS 44101.

CIRCLE 26 ON READER SERVICE CARD