Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded...

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Cours du 14‐10‐2013 Longévité cérébrale

Transcript of Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded...

Page 1: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

Cours du 14‐10‐2013

Longévité cérébrale

Page 2: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 3: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 4: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

TDP1: tyrosil‐DNA phosphodiesteraseAPTX: aprataxinPNKP: polynucleotide kinase 3’‐phosphatase

Page 5: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 6: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

H1H1

histone sur DNA linkerparticipe au “packing” du nucléosome

Page 7: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

γH2AX 

Page 8: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 9: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

?  plutôt le contraire ?

Page 10: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 11: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 12: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 13: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
Page 14: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

Replicative Senescence, Chronological aging

Oncogne‐induced senescence

Hutchinson‐Gilford Progeria Syndrom

Caloric Restriction

Page 15: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled
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Page 17: Cours du 14-10-2013 - Collège de France · 2013-12-17 · Fig. 4. Repair of single stranded lesions. Figure shows a simplified model for single strand break repair (SSBR) and transcription-coupled

Enhanced Repair and Strengthening of Reinforced … · Enhanced Repair and Strengthening of Reinforced Concrete Beams Utilizing External Fiber Reinforced Polymer Sheets and Novel

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A census of α-helical membrane proteins in double-stranded ... · RESEARCH ARTICLE Open Access A census of α-helical membrane proteins in double-stranded DNA viruses infecting bacteria

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Codon populations in single-stranded whole human genome ...creationwiki.org/pool/images/7/71/DraftJean-claudePerez...Codon populations in single-stranded whole human genome DNA are

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Therapeutic Class Overview β -Agonists Single-Entity Agents Agonists Single-Entity Agents.pdfTherapeutic Class Overview β2-Agonists Single-Entity Agents Therapeutic Class Overview/Summary:

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