0 100 200 Condensed TUNEL + cells (%) WT RanBP9 Tg B The scale bar represents 50 m A CA1 TUNEL Wild...
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0 100 200 Condensed TUNEL + cells (%) WT RanBP9 Tg B The scale bar represents 50m A CA1 TUNEL Wild Type RanBP9 Tg P<0.0005 * Supplemental Fig. S1
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Transcript of 0 100 200 Condensed TUNEL + cells (%) WT RanBP9 Tg B The scale bar represents 50 m A CA1 TUNEL Wild...
0
100
200
Co
nd
en
se
d
TU
NE
L +
ce
lls
(%
)
WT RanBP9 Tg
B
The scale bar represents 50m
ACA1
TU
NE
L
Wild Type
RanBP9 Tg
P<0.0005
*
Supplemental Fig. S1
Supplemental Fig. S2
A B
C D
Supplemental Fig. S3
Supplemental Fig. S4
Thy1.2
pEYFP-N1
GFP-
RanBP9VC
RanBP9
O.D
at 4
90/6
90 n
m
VC RanBP9
pEYFP-N1 GFP RanBP9
B
CUL: 2.42UR: 28.40LL: 47.36LR: 21.82
UL: 0.68UR: 24.56LL: 29.62LR: 45.14
RanBP9
21.87%
45.14%
A VCP
I
Annexin V
Annexin V
Supplemental Fig. S5
50
10075
37
25
20
1015
150250
Stacking gel
6E10
O F
4
tetramer trimer dimermonomer
fibril
D
HT22 Cells
Cont. RanBP9siRNA siRNA
* RanBP9
* β-actin
Supplemental Fig. S6
A B
* Cofilin
* β-actin
Cont. CofilinsiRNA siRNA
C
Cont
rol
Cont
rol
DAP
T 5μ
M
DAP
T 5μ
M
APP-FL
APP-CTFs
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