Ορίζοντας τη Συναισθηµατική...

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(HARV REV PSYCHIATRY 2012, 20:298-308)

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DDOOII:: 1100..33110099//1100667733222299..22001122..774477779988

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!"!#"$%&'("'1. Shelder J, Westen D. Rening personality disorder diag¬nosis:

integrating science and practice. Am J Psychiatry 2004;161:1350–65. 2.Anestis MD, Peterson CB, Bardone-Cone AM, et al. Affective

lability and impulsivity in a clinical sample of women withbulimia nervosa: the role of affect in severely dysregulatedbe¬haviour. Int J Eat Disord 2009;42:259–66.

3. Koenigsberg HW. Affective instability: toward an integrationof neuroscience and psychological perspectives. J PersonalDisord 2010;24:60–82.

4. Benazzi F. A relationship between bipolar II and borderlineper¬sonality disorder? Prog Neuropsychophamacol BiolPsychiatry 2008;32:1022–9.

5. Benazzi F, Akiskal HS. A downscaled practical measure ofmood lability as a screening tool for bipolar II. J Affect Dis¬ord2005:84:225–32.

6. Perugi G, Fornaro M, Akiskal HS. Are atypical depression,bor¬derline personality disorder and bipolar II disorderoverlapping manifestations of a common cyclothymic diathesis?World Psy¬chiatry 2011:1:45–51.

7. Links PS, Eynan R, Heisel MJ, Nisenbaum R. Elements ofaffective instability associated with suicidal behaviour inpa¬tients with borderline personality disorder. Can J Psychiatry2008;53:112–6.

8. Linehan MM, Heard H. Dialectal behaviour therapy forborder¬line personality disorder. In: Clarkin JF, Marziali E,

Tomos6_t4 7/4/14 4:10 PM Page 13

[14] !""#$%&' ()*%+,%&' -#. /+0#")1-%&2. !3%0-2µ#.

Munroe-Blum H, eds. Borderline personality disorder: clinicaland em¬pirical perspectives. New York: Guilford, 1992.

9. Tragesser SL, Solhan M, Schwartz-Mette R, Trull TJ. Therole of affective instability and impulsivity in predicting futureBPD features. J Personal Disord 2007;21:603–14.

10. Tragesser SL, Robinson RJ. The role of affective instabilityand UPPS impulsivity in borderline personality disorderfeatures. J Personal Disord 2009;23:370–83.

11. Domes G, Schulze L, Herpertz SC. Emotion recognition inbor¬derline personality disorder: a review of the literature.J Per¬sonal Disord 2009;23:6–19.

12. Yen S, Shea MT, Sanislow CA, et al. Borderline personalitydis¬order criteria associated with prospectively observedsuicidal behaviour. Am J Psychiatry 2004;161:1296–8.

13. Linn L. Clinical manifestations of psychiatric disorders. In:Ka¬plan HI, Freedman AM, Sadock BJ, eds. Comprehensivetext¬book of psychiatry. Baltimore, London: Williams &Wilkins, 1980:1018.

14. Damasio AR. Descartes’ error: emotion, reason, and thehuman brain. New York: Penguin Putnam, 1994.

15. LeDoux JE. Emotion: clues from the brain. Annu Rev Psychol1995;46:209–35.

16. Fonagy P, Gergely G, Jurist E, Target M. Affect regulation,mentalization, and the development of the self. New York:Other, 2004.

17. Ebner-Priemer UW, Kuo J, Scholtz W, et al. Distress andaf¬fective dysregulation in patients with borderline personalitydisorder: a psychophysiological ambulatory monitoringstudy. J Nerv Ment Dis 2008;196:314–20.

18. Jahng S, Wood PK, Trull TJ. Analysis of affective instabilityin ecological momentary assessment: indices using successivedif¬ference and group comparison via multilevel modeling.Psychol Methods 2008;13:354–75.

19. Westen D, Mudderisoglu S, Fowler C, Shedler J, Koren D.Af¬fect regulation and affective experience: individualdifferences, group differences and measurement using aQ-sort procedure. J Consult Clin Psychol 1997;65:258–439.

20. American Psychiatric Association. Diagnostic and statisticalmanual of mental disorders. 4th ed., text rev. Washington,DC: American Psychiatric Press, 2000.

21. Rosenthal MZ, Gratz KL, Kosson DS, Cheavens JS, LejuezCW, Lynch TR. Borderline personality disorder and emotionalre¬sponding: a review of the research literature. Clin PsycholRev 2008;28:75–91.

22. Siever L, Davis K. A psychobiological perspective on theper¬sonality disorders. Am J Psychiatry 1991;148:1647–58.

23. Davidson R. Anterior electrophysiological asymmetries,emo¬tion, and depression: conceptual and methodologicalconun¬drums. Psychophysiology 1998;35:607–14.

24. Miller JD, Pilkonis PA. Neuroticism and affective instability:the same or different? Am J Psychiatry 2006;163:839–45.

25. Larsen R, Diener E, Emmons RA. Affect intensity andreactions to daily life events. J Pers Soc Psychol 1987;5:803–14.

26. Gross JJ. Emotion regulation: affective, cognitive, and socialconsequences. Psychophysiology 2002;39:281–91.

27.Ebner-Priemer UW, Welch SS, Grossman P, Reisch T, LinehanMM, Bohus M. Psychophysiological ambulatory assessmentof affective dysregulation in borderline personality disorder.Psy¬chiatry Res 2007;150:265–75.

28. Stein KF. Affective instability in adults with a borderlineper¬sonality disorder. Arch Psychiatr Nurs 1996;18:405–15.

29. Koenigsberg HW, Harvey PD, Mitropoulou V, et al. Character¬izingaffective instability in borderline personality disorder. Am

J Psychiatry 2002;159:784–8. 30. Nica EI, Links P. Affective instability in borderline personality

disorder: experience sampling ?ndings. Curr PsychiatryRep 2009;11:74–81.

31. Henry C, Mitropoulou V, New AS, Koenigsberg HW, SilvermanJ, Siever LJ. Affective instability and impulsivity in borderlinepersonality and bipolar II disorders: similarities anddifferences. J Psychiatr Res 2001;35:307–12.

32. Herpertz S, Gretzer A, Muhlbauer V, Steinmeyer EM, SassH. Experimental detection of inadequate affect regula¬tionin patients with self-mutilating behaviour. Nervenarzt1998;69:410–8.

33. Stiglmayr CE, Shapiro DA, Stieglitz RD, et al. Experienceof aversive tension and dissociation in female patients withbor¬derline personality disorder, a controlled study. JPsychiat Res 2001;35:111–8.

34. Levine D, Marziali E, Hood J. Emotion processing in borderlinepersonality disorders. J Nerv Ment Dis 1997;185:240–6.

35. Links PS, Eynan R, Heisel MJ, et al. Affective instability andsuicidal ideation and behavior in patients with borderlineper¬sonality disorder. J Personal Disord 2007;21:72–86.

36. Comtois KA, Cowley DS, Dunner DL, Roy-Byrne PP.Relation¬ship between borderline personality disorder andaxis I diag¬nosis in severity of depression and anxiety. JClin Psychiatry 1999;60:752–8.

37. De la Fuente JM, Bobes J, Vizuete C, Mendlewicz J. Biolog¬icalnature of depressive symptoms in borderline personalitydisorder: endocrine comparison to recurrent brief and majordepression. J Psychiatr Res 2002;36:137–45.

38. Bellodi L, Battaglia M, Gasperini M, Scherillo P, BrancatoV. The nature of depression in borderline depressed patients.Compr Psychiatry 1992;33:128–33.

39. Gratz Kl, Rosenthal MZ, Tull MT, Lejuez CW, GundersonJG. An experimental investigation of emotion dysregulationin bor¬derline personality disorder. J Abnorm Psychol2006;115:850–3.

40. Kuo JR, Linehan MM. Disentangling emotion processes inbor¬derline personality disorder: physiological and self-reported as¬sessment of biologival vulnerability, baselineintensity, and re¬activity to emotionally evocative stimuli.J Abnorm Psychol 2009;118:531–44.

41.Henry C, Swendsen J, Van den Bulke D, Sorbara F, Demotes-Mainard J, Leboyer M. Emotional hyper-reactivity as afun¬damental mood characteristic of manic and mixedstates. Eur Psychiatry 2003;18:124–8.

42.Henry C, Van den Bulke D, Bellivier F, et al. Affective labil¬ityand affect intensity as core dimensions of bipolar disordersduring euthymic period. Psychiatry Res 2008;159:1–6.

43.M’Bailara K, Demotes-Mainard J, Swendsen J, Mathieu F,Leboyer M, Henry C. Emotional hyper-reactivity in normo¬thymicbipolar patients. Bipolar Disord 2009;11:63–9.

44.Russell J, Moskovitz D, Zuroff D, Sookman D, Paris J. Sta¬bilityand variability of affective experience and interpersonalbehaviour in borderline personality disorder. J AbnormPsychol 2007;116:578–88.

45.Conklin CZ, Bradley R, Westen D. Affect regulation inborder¬line personality disorder. J Nerv Ment Dis 2006;194:69–77.

46.Trull TJ, Solhan MB, Tragesser SL, et al. Affective instabil¬ity:measuring a core feature of borderline personality disor¬derusing ecological momentary assessment. J Abnorm Psychol2008;117:647–61.

47.Cowdry RW, Gardner DL, O’Leary KM, Leibenluft E, RubinowDR. Mood variability: a study of four groups. Am J Psychiatry

Tomos6_t4 7/4/14 4:10 PM Page 14

!"µ#$ 6 - !%&'#$ 4 [15]

1991;148:1505–11. 48.Koenigsberg HW, Fan J, Ochsner KN, et al. Neural correlates

of the use of psychological distancing to regulate responsesto negative social cues: a study of patients with borderlineperson¬ality disorder. Biol Psychiatry 2009;66:854–63.

49.Benazzi F. Borderline personality-bipolar spectrum relation¬ship.Prog Neuropsychopharmacol Biol Psychiatry 2006;30: 68–74.

50.van Dijke A, Ford JD, van der Hart O, van Son M, van derHeijden P, Buhring M. Affect dysregulation in borderlinepersonality disorder and somatoform disorder: differentiat¬ingunder and over-regulation. J Personal Disord 2010;24:296–311.

51.Bradley R, Westen D. The psychodynamics of borderlineper¬sonality disorder: a view from developmental psychopathology.Dev Psychopathol 2005;17:927–57.

52.Siever J, Weinstein LN. The neurobiology of personalitydisor¬ders: implications for psychoanalysis. J Am PsychoanalAssoc 2009;57:361–98.

53.Johnson PA, Hurley RA, Benkelfat C, Herpertz SC, TaberKH. Understanding emotion regulation in borderline personal¬itydisorder: contributions of neuroimaging. J NeuropsychiatryClin Neurosci 2003;15:397–402.

54.Figueroa E, Silk KR. Biological implications of childhoodsex¬ual abuse in borderline personality disorder. J PersonalDisord 1997;9:92–104.

55.Coccaro E F, Siever LJ, Klar AM, et al. Serotonergic studiesin patients with affective and personality disorders. ArchGen Psychiatry 1989;46:587–99.

56.Silbersweig D, Clarkin JF, Goldstein M, et al. Failure offrontolimbic inhibitory function in the context of negativeemotion in borderline personality disorder. Am J Psychiatry2007;164:1832–41.

57.Siever LJ. Endophenotypes in the personality disorders.Dia¬logues Clin Neurosci 2005;7:139–51.

58.Savitz JB, Ramesar RS. Personality: is it a viable endopheno¬typefor genetic studies of bipolar affective disorder? BipolarDisord 2006;8:322–37.

59.Glaser JP, van Os J, Mengelers R, Myin-Gereys I. A momen¬taryassessment study of the reputed emotional phenotypeassociated with borderline personality disorder. PsycholMed 2008;38:1231–9.

60.Clayton PJ, Ernst C, Angst J. Premorbid personality traitsof men who develop unipolar and bipolar disorders. EurArch Psy¬chiatry Clin Neurosci 1994;243:340–6.

61.Angst J, Gamma A, Endrase J. Risk factors for bipolar anddepression spectra. Acta Psychiatr Scand 2003;108 suppl:15–9.

62.Hess C, Reif A, Strobel A, et al. A functional dopamine-beta¬hydroxylase gene promoter polymorphism is associatedwith impulsive personality styles, but not with affectivedisorders. J Neural Transm 2009;116:121–30.

63.Pinkham L, Horvath TB, Coccaro EF, et al. Affective andimpulsive personality disorder traits in the relatives ofpa¬tients with borderline personality disorder. Am J Psychiatry1991;148:1378–85.

64.Skodol AE, Gunderson JG, Pfohl B, Widiger TA, Livesley WJ,Siever LJ. The borderline diagnosis I: psychopathol¬ogy,comorbidity, and personality structure. Biol Psychiatry2002;51:936–50.

65.Livesley WJ, Jackson DN, Schroeder ML. Factorial structureof traits delienating personality disorders in clinical andgeneral populations. J Abnorm Psychol 1992;101:432–40.

66.Distel MA, Willemsen G, Ligthart L, et al. Genetic covariance

structure of the four main features of borderline personalitydisorder. J Personal Disord 2010;24:427–44.

67.Kavoussi RJ, Coccaro EF. The amphetamine challenge testcor¬relates with affective instability in healthy volunteers.Psychi¬atry Res 1993;48:219–28.

68.Coccaro EF, Siever LJ, Klar HM, et al. Serotonergic studiesin patients with affective and personality disorders. Correlateswith suicidal and impulsive aggressive behavior. Arch GenPsy¬chiatry 1989;46:587–99.

69.Depue R. A neurobiological framework for the structure ofper¬sonality and emotion: implication for personality disorders.In: Clarkin JF, Lenzenweger MF, eds. Major theories ofpersonality disorder. New York, London: Guilford, 1996:347–90.

70.MacKinnon DF, Pies R. Affective instability as rapid cycling:theoretical and clinical implications for borderline personal¬ityand bipolar spectrum disorders. Bipolar Disord 2006;8:1–14.

71.Hazlett EA, New AS, Newmark R, et al. Reduced anteriorand posterior cingulate gray matter in borderline personalitydisor¬der. Biol Psychiatry 2005;58:614–23.

72.Filardi da Rocha F, Malloy-Diniz L, Alvaes de Sousa KC, etal. Borderline personality features possibly related tocingulated and orbitofrontal cortices dysfunction due toschizencephaly. Clin Neurol Neurosurg 2008;110:396–9.

73.Herpertz S, Dietrich TM, Wenning B, et al. Evidence ofabnor¬mal amygdala functioning in borderline personalitydisorder: a functional MRI study. Biol Psychiatry 2001;50:292–8.

74.Pavuluri MN, Herbener ES, Sweeney JA. Affect regulation:a systems neuroscience perspective. Neuropsychiatr DisTreat 2005;1:9–15.

75.Donegan NH, Sanislow CA, Blumberg HP, et al. Amygdalahy¬perreactivity in borderline personality disorder: implicationsfor emotional dysregulation. Biol Psychiatry 2003;54:1284–93.

76.Goldin PR, McRae K, Ramel W, Gross JJ. The neural basesof emotion regulation: reappraisal and suppression ofnegative emotion. Biol Psychiatry 2008;63:577–86.

77.Andrulonis PA, Vogel NG. Comparison of borderline personal¬itysubcategories to schizophrenic and affective disorders. BrJ Psychiatry 1984;144:358–63.

78.Ruocco AC. The neuropsychology of borderline personalitydis¬order: a meta-analysis and review. Psychiatry Res2005;137: 191–202.

79.New AS, Hazlett EA, Buchsbaum MS, et al. Amygdala¬prefrontaldisconnection in borderline personality disorder.Neuropsychopharmacology 2007;32:1629–40.

80.Post RM. Transduction of psychosocial stress into theneu¬robiology of recurrent affective disorder. Am J Psychiatry1992;149:999–1010.

81.Meaney MJ. Epigenetics and the biological de?nition of geneX environment interactions. Child Dev 2010;81:49–71.

82.Koukopoulos A, Sani G, Koukopoulos AE, Albert MJ, GirardiP, Tatarelli R. Endogenous and exogenous cyclicity andtempera¬ment in bipolar disorder: review, new data andhypotheses. J Affect Disord 2006;96:165–75.

83.Linehan MM, Heard H, Armstrong HE. Naturalistic follow-up of a behavioral treatment for chronically parasuicidalborder¬line patients. Arch Gen Psychiatry 1993;50:971–4.

84.Choi-Kain LW, Zanarini MC, Frankenburg FR, FitzmauriceGM, Reich DB. A longitudinal study of the 10-year courseof interpersonal features in borderline personality disorder.J Per¬sonal Disord 2010;24:365–76.

85.Levitt AJ, Joffe RT, Ennis J, McDonald C, Kutcher SP. Theprevalence of cyclothymia in borderline personality disorder.

Tomos6_t4 7/4/14 4:10 PM Page 15

[16] !""#$%&' ()*%+,%&' -#. /+0#")1-%&2. !3%0-2µ#.

J Clin Psychiatry 1990;51:335–9. 86.86. Goldberg JF, Garno JL. Age at onset of bipolar disorder

and risk for comorbid borderline personality disorder. BipolarDisord 2009;11:205–8.

87.Paris J, Gunderson J, Weinberg I. The interface betweenbor¬derline personality disorder and bipolar spectrumdisorders. Compr Psychiatry 2007;48:145–54.

88. Paris J. Implications of long-term outcome research forthe management of patients with borderline personalitydisorder. Harv Rev Psychiatry 2002;10:315–23.

89. Morey LC. The personality personality assessment inventory:professional manual. Odessa, FL: Psychological AssessmentResources, 1991.

90. Harvey PD, Greenberg BR, Serper MR. The affective labilityscales: development, reliability, and validity. J Clin Psychol1989;5:786–93.

91. Zittel C, Westen D. Subtyping borderline personality disorder.Invited presentation at the New Directions in Borderline Per¬sonalityDisorder II Conference, Minneapolis, MN, May 2002.

92. Posner M, Rothbart M, Vizueta N, et al. Attentional mecha¬nismsof borderline personality disorder. Proc Natl Acad Sci U SA 2002;99:16366–70.

93. Ebner-Priemer UW, Eid M, Kleindientst N, Stabenow S,Trull TJ. Analytic strategies for understanding affective(in)stability and other dynamic processes in psychopathology.

J Abnorm Psychol 2009;118:195–202. 94. Stiglmayr CE, Grathwol T, Linehan MM, Ihorst G, Fahrenberg

J, Bohus M. Aversive tension in patients with borderlineper¬sonality disorder: a computer based controlled ?eldstudy. Acta Psychiatr Scand 2005;117:139–47.

95. Ingenhoven T, Lafay P, Rinne T, Passchier J, DeuvinvoordenH. Effectiveness of pharmacotherapy for severe personalitydis¬order: meta-analyzes of randomized clinical trials. JClin Psy¬chiatry 2010;71:14–25.

96. Ingenhoven TJ, Deuvinvoorden HJ. Differential effective¬nessof antipsychotics in borderline personality disorder: meta-analyses of placebo-controlled, randomized clinical tri¬alson symptomatic outcome domains. J Clin Psychopharmacol2011;31:489–96.

97. Saunders EF, Silk KR. Personality trait dimensions of thephar¬macological treatment of borderline personalitydisorder. J Clin Psychopharmacol 2009;29:461–7.

98. Reich DB, Zanarini MC, Bieri KA. A preliminary study oflam¬otrigine in the treatment of affective instability inborderline personality disorder. Int Clin Psychopharmacol2009;24:270–5.

99. Mercer D, Douglass AB, Links PS. Metaanalyses of moodstabilizers, antidepressants and antipsychotics in thetreat¬ment of borderline personality disorder. J PersonalDisord 2009;23:156–74.

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