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Zhang and Wang J Hematol Oncol 2020 13:165 https:doiorg101186s13045-020-00990-3 REVIEW Targeting the Wntβ-catenin signaling pathway in cancer Ya Zhang123456 and Xin Wang123456*…
http://www.jcancer.org 4196 Research Paper MicroRNA-1246 by Targeting AXIN2 and GSK-3β Overcomes Drug Resistance and Induces Apoptosis in Chemo-resistant Leukemia Cells
Introduction Peroxisomes are ubiquitous eucaryotic organelles that contribute to important metabolic processes, including hydrogen peroxide metabolism, the β-oxidation of…
SUPPLEMENTARY DATA SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin Christèle Maison, Delphine Bailly, Danièle Roche, Rocío Montes de Oca,…
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infection Lin Yea1 Jiaming Wangab Ashley I Beyerc…
UNIVERSIDADE DE LISBOA FACULDADE DE FARMÁCIA Targeting MicroRNAs for Modulation of the Anti-Tumor Human γδ T Cell Differentiation Master Thesis Dissertation Gisela Silva…
Nuclear targeting of β-catenin and p120ctn during thrombin-induced endothelial barrier dysfunction Cora ML Beckers1 Juan J García-Vallejo2 Victor WM van Hinsbergh1 and…
Int J Clin Exp Med 2018118:8094-8101 wwwijcemcom ISSN:1940-5901IJCEM0068714 Original Article Targeting STAT3 signaling alleviates severity of fungal keratitis by suppressing…
1374 Abstract. – OBJECTIVE: To investigate the role of long noncoding RNA lncRNA UCA1 in the multiple myeloma MM development. PATIENTS AND METHODS: In samples of MM, the…
Verastem, Inc. 215 First Street Suite 440 Cambridge Massachusetts 02142 Verastem, Inc., Cambridge MA ABSTRACT INTRODUCTION RESULTS VS-507 inhibits Wntβ-catenin signaling…
Title: MOLECULAR PATHWAYS: Targeting the TGF-β Pathway for Cancer Therapy Authors: Anna L. Smith1, Tyler P. Robin1,2, and Heide L. Ford3,4 Affiliations: 1Program in Molecular…
Interleukin 1α Sustains the Expression of Inflammatory Factors in Human Pancreatic Cancer Microenvironment by Targeting Cancer-Associated FibroblastsInterleukin 1α
UNC/UCSF Frank M. Longo, Stanford University Stanford Academic/mechanistic studies ADDF Alzheimer’s Association NIA U01 NINDS R21 Taube Family Koret Fdn Jean Perkins Fdn…
Targeting Transcription Factor NF-κB by Dual Functional Oligodeoxynucleotide Complex for Inhibition of Neuroinflammation A dissertation submitted to the Graduate School…
Nuclear targeting by Nuclear Localization Signals NLS Richardson and Laskey 1988 The nuclear import pathway of proteins containing a classical Nuclear Localization Signal…
In vivo efficacy and safety of RGX-019, a MerTK targeting monoclonal antibody Presented at: 2020 AACR Annual meeting Shugaku Takeda1, Celia Andreu-Agullo1 MerTK Ligand Gas6…
Advancing Phosphor Science: Targeting high-efficiency phosphors via informatics Jakoah Brgoch PhD Department of Chemistry University of Houston Email: jbrgoch@uhedu λ White…
Joanne Donovan MD PhD Catabasis Pharmaceuticals Cambridge MA Targeting NF-κB with Edasalonexent for Muscle and Bone Health in Duchenne Muscular Dystrophy 2 Disclosures This…
Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit Evzen Boura and James H. Hurley1 Laboratory of Molecular…
Journal of Cancer 2018, Vol. 9 http://www.jcancer.org 71 JJoouurrnnaall ooff CCaanncceerr 2018; 9(1): 71-80. doi: 10.7150/jca.22113 Research Paper Targeting LncRNA-MALAT1…