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Inpharma 1596 - 14 Jul 2007 SP 233 [Caprospinol] * shows the potential to reverse plaque-related brain injury, according to results from a study conducted in a rat model of Alzheimer’s disease. SP 233 was associated with a substantial decrease in β-amyloid plaque in rats’ brains, accompanied by restoration of memory to baseline levels (p = 0.002). * Samaritan Pharmaceuticals Samaritan Pharmaceuticals Inc. Samaritan’s Alzheimer’s Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimer’s Disease. Media Release : 10 Jul 2007. Available from: URL: http:// www.samaritanpharma.com 809077738 1 Inpharma 14 Jul 2007 No. 1596 1173-8324/10/1596-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Inpharma 1596 - 14 Jul 2007

■ SP 233 [Caprospinol]* shows the potential toreverse plaque-related brain injury, according toresults from a study conducted in a rat model ofAlzheimer’s disease. SP 233 was associated with asubstantial decrease in β-amyloid plaque in rats’brains, accompanied by restoration of memory tobaseline levels (p = 0.002).* Samaritan Pharmaceuticals

Samaritan Pharmaceuticals Inc. Samaritan’s Alzheimer’s Drug CaprospinolSuggests Brain May be Able to Heal From Alzheimer’s Disease. MediaRelease : 10 Jul 2007. Available from: URL: http://www.samaritanpharma.com 809077738

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Inpharma 14 Jul 2007 No. 15961173-8324/10/1596-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved