phosphorylation by ZAP-70 phosphorylation by Lck … · lat y127 lat y132 lat y127/132 lat y171 lat...
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Transcript of phosphorylation by ZAP-70 phosphorylation by Lck … · lat y127 lat y132 lat y127/132 lat y171 lat...
LAT
Y12
7
LAT
Y13
2
LAT
Y12
7/13
2
LAT
Y17
1
LAT
Y19
1
LAT
Y22
6
LAT
Y22
6F
SLP
-76
Y11
3
SLP
-76
Y12
8
SLP
-76
Y14
5
p38α
Y32
30
3
6
9
12
15
enric
hmen
t rel
ativ
e to
LA
T Y
226F
TCRζ
Y72
/83
TCRζ
Y72
TCRζ
Y83
TCRζ
Y11
1/12
3
TCRζ
Y11
1
TCRζ
Y12
3
TCRζ
Y14
2/15
3
TCRζ
Y14
2
TCRζ
Y15
3
TCRζ
Y14
2/15
3F
0
3
6
9
12
15
enric
hmen
t rel
ativ
e to
LA
T Y
226F
LAT
Y36
LAT
Y45
LAT
Y64
LAT
Y70
LAT
Y11
00
3
6
9
12
15
enric
hmen
t rel
ativ
e to
LA
T Y
226F
reported ZAP-70 substrates reported Lck substrates other LAT tyrosines
phosphorylation by ZAP-70 phosphorylation by Lck
refe
renc
e
A
B
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