MAMMAry gland

By :Erma Safitri, M.Si., Drh.

Faculty of Veterinary MedcineAirlangga University

Surabaya

ANATOMY OF MAMMARY GLANDModificated : Skin Gland + Nepple + Water Milk

Homologue : Sweat Gland

Based of Location :

1. Inguinale : Cow, Ewe, Goat, Buffalo, Mare

2. Pectoralis : Elephant & Primate

3. Abdominalis : Sow, Dog, Cat

Mammary Gland : Σ, Form, Measurrement & Located : Different

Base Structure : Same

Consist of :

1. Sekretion Tissue/Parenchima: Epithel Sekretion Cell

(ALVEOLI)

2. Binding Tissue (STROMA)

In 1 Kuartir consist of 1 Teat Sisterna & 1 Streak Canal (Teat Meatus)

In 1 Kuartir consist 2 Teat Sisterna & 2 streak canal

In 1 Kuartir consist of Many Teat Sisterna & Many Streak Canal

Milk Product ↗ Average Milk Product Milk Product ↓

With TRUNKFor suckling With Mouth

For suckling

Process PencarianPutting Susu

With Botle milk

Adhesion of Mammary Gland by :1. Skin2. Lig. Suspensorium medialis : Yellow, Elastis

Tissue, Lamellae Formed/ Lempengan3. Lig suspensorium lateralis: Fibrous Tissue, Terminate on Tendon from os Ischium & Pubis

ALVEOLI : like Grappes FruitLike Lung TissueDiameter : 0,1 – 0,3 mmConsist : Stratum of Epitel Secretori Cell

Function : (Side of Produce/ Milk Syntesis)1.Take of Nutrient from Blood2. Change of nutrient from Blood3. Flow of Nutrient to the Lumen

Each of Kuartir separated in :Blood Suplai , Nervous Suplai & Ligamentum (Lateralis & Medialis)

Each of Mammary separated in :1.Suplai Darah2. Suplai Syaraf3. Aparatus Suspensorius: Lig. Susp. Lat & Med

SIRKULATION1. PUDICUM EXTERNA Artery MAMMARICA EXTERNA Artery CAPILER System in the ALVEOLUS2. VENA : Anastomose - 2 track = CAVA Vein PUDICUM EXTERNA Vein SUBCUTANEUS ABDOMINALIS Vein (Milk Vein)

INERVATION/ STIMULATION :1. HORMONE MECHANISME2. NEURAL MECHANISME : A. AUTONOMIC : INTERNAL (Induk) B. SOMATIS : EKSTERNAL (Suckling, Habitualis)

PROCCES OF MILK

SYNTESIS

PROLIFERATION & FUNCTION OF MAMMARY GLAND:

1. MAMMOGENESIS Proliferation of Mammary Gland to indicated with Proliferation of Cell

2. LACTOGENESIS Sintesys to Produce/ Milk Sekretion

3. GALACTOPOIESIS Maintenance of Milk Suplai (Laktation)

4. MILK EJECTION Milk go out in large number from ALVEOLI Ejection from Mammary Gland b/ Suckling

1. MAMMOGENESIS : Proliferation control of Mammary Gland E2 : Proliferation of Ductus system (in Every Estrous & Pregnant) P4 : Proliferation of Mammary Alveolar

HORMONE MECHANISME HIPOTALAMUS

GH PRL HIPOFISA ANTERIOR

DUCTUS OVARIUM ALVEOLI E2

P4

PLACENTA PLACENTALACTOGEN

PLASENTAL LACTOGEN = SOMATOMAMMOTROPHINE Structure & Biology Aktivity Like GH & PRL Produced by Placenta

2. LACTOGENESIS : At GRAVID Phase: E2 + P4 ↗↗ PRL↙ Stopped At PARTUS/ OVARIECTOMY/ INVOLUTIO CL Become

MECHANISME :PARTUS P4↙↙↙ & E2↙

HIPOFISA ANTERIOR

PROLAKTIN

MILK SECRETION

3. GALACTOPOIESIS : Hipofisa Gland : Important for Laktation maintenance PRL : shock for milk secretion

HORMONES THE ROLE OF GLAND PROLIFERATION FSH

LHLTH/ PRLACTHTSHE2P4PLASENTA LACTOGEN

SUCKLING

IMPULS SYARAF

N. PARAVENTR. HIPOTHALAMUS

OXITOCYN

HIPOFISA POST.

BLOOD VESSEL

CONTRACTION OF MYOEPITHEL CELLS

MILK EJECTION

Trac. Hipothalamico- Hipofiseal

LAKTASI TDD 2 FASE: SEKRESI & PELEPASAN AS

MEKANISME SEKRESI:

HIPOFISA ANTERIOR

FSH & LH

OVARIUM

PERTUMB. DUCT P4↗↗

E2↗ PERTUMB. ALVEOLI

PARTUS

E2↙, P4↙ & Suckling

H.A. LTH

INISIASI LAKTASI

1. There isn’t Suckling2. Disturb of Milk Ejection : Worry, Afraid,

Bashful, Sad & High Emotion3. Tx/ EPINEPPRIN: Stimulate inhibiting of

nervous to Neurohypofisis so that didn’t out of oxytocin

4. Cutting of Pituitary stalk5. Demaging of Hipothalamus region

STOPPED LAKTATION RATHER QUICKLYIf Mammary Gland full filled b/ :

there isn’t Suckling/ Disturb milk ejection

ALVEOLI produced continuesly & full filed

Raising of mammary gland tension

b/ There isn’t Suckling/ Distrubed

Tension will grow up reached Max point

MILK SEKRETION DELAYED

1. Time must constant squezing 2. Sound of bucket3. There is a Calf

4. Washing of Mammary5. Look at food (Habitualis)6. Genital Manipulation7. Matting8. R/ Oxytocin eksogen9. Electrical Stimulate for Tractus

Supraoptico-Hipofisialis

= Basket, Arround of AlveoliIt’s. Efector contractile tissueIt’s Cells with stuck out, branch off &

not Arranged Can Contraction with R/ : Local Oksitocyn/ Vasopresin,

Histamin, Asetilcholine & Philocarpine