Tzvika Hartman Elad Verbin Bar Ilan University Tel Aviv University
Biomarkers for neurodegeneration - ADX Home page · EUROIMMUN AG · D-23560 Luebeck (Germany) ·...
Transcript of Biomarkers for neurodegeneration - ADX Home page · EUROIMMUN AG · D-23560 Luebeck (Germany) ·...
Tau pathologyP-tau (181)
Apolipoprotein EPhenotype: ApoE 4, pan-ApoE
Genotype: ApoE ε2, ε3, ε4
Amyloid pathologyA (1-42)A (1-40)A (1-38)
Neuronal degenerationTotal-tau
P-neurofilament H
Pre-/post-synapticNeurogranin (trunc P75)
BACE1
EUROIMMUN AG · D-23560 Luebeck (Germany) · Seekamp 31 · Tel +49 451 58550 · Fax 5855591 · E-mail [email protected]
Biomarkers for neurodegeneration
EUROIMMUN
Automatable
Quality control samples for all tests
Aligned protocols
Fully validated
Biomarkers for synaptic integrity
Biomarkers for brain pathology
Risk factors for neurodegenerative diseases
EUROIMMUN AG · D-23560 Luebeck (Germany) · Seekamp 31 · Tel +49 451 58550 · Fax 5855591 · E-mail [email protected]
Available product Description CSF Plasma Order no.
Beta-Amyloid (1-38) ELISATest kit for the quantitative determination of beta- amyloid (1-38) as an additional diagnostic tool in suspected clinical amyloid pathology of the brain.
EQ 6501-9601-LEQ 6501-9601
Beta-Amyloid (1-40) ELISA
Test kit for the quantitative determination of beta- amyloid (1-40). Can be used to calculate beta-amyloid (1-42)/beta-amyloid (1-40) as an additional diagnostic tool in suspected amyloid pathology of the brain.
EQ 6511-9601-LEQ 6511-9601
Beta-Amyloid (1-42) ELISATest kit for the quantitative determination of beta- amyloid (1-42) as an additional diagnostic tool in suspected clinical amyloid pathology of the brain.
EQ 6521-9601-LEQ 6521-9601
Total-Tau ELISATest kit for the quantitative determination of total tau for the diagnosis of neuronal apoptosis.
EQ 6531-9601-L
Phosphorylated-Tau ELISAP-tau (T181) determination is an additional diagnostic tool in suspected tauopathy in the brain of patients with neurodegenerative disorders.
Available Q3/2016
Beta-Amyloid Control SetCSF sample set with target values. Can be used for on-site training as well as regular internal quality con-trol of amyloid and tau measurements.
Available Q3/2016
ApoE4 ELISA
Test kit for ApoE4 protein determination. Measureable ApoE4 protein concentrations indicate at least one ApoE allele that is a risk factor for the develop ment of Alzheimer’s disease.
Available Q3/2016
Pan-ApoE ELISATest kit for the quantitative determination of pan-ApoE.
Available Q3/2016
BACE1 ELISATest kit for the determination of BACE1 protein con-centration.
Available Q3/2016
Neurogranin (trunc P75) ELISA
Test kit for the quantitative determination of neuro-granin.
Available Q3/2016
pNfH ELISA
Test for the quantitative determination of phosphory-lated neurofilament heavy chain. Can be used as an additional tool for the early diagnosis of motoneuro- nal diseases like amyotrophic lateral sclerosis.
Available Q3/2016
Available product Description Full blood sample Order no.
EUROArray APOE Direct
Test system for molecular genetic diagnostics of Alzheimer‘s disease and type III hyperlipoprotein emia, as well as other diseases associated with the allels ε2, ε3 and/or ε4 of the APOE gene.
MN 5710-0803-VMN 5710-0505-VMN 5710-1005-VMN 5710-2005-V
Antigen detection:
Molecular diagnostics:
HQ_1100_I_UK_A01, 06/2016