- + - +
6
- + - + NIH3T3 Low High TAZ (short) β-actin TAZ (long) - + - + MEF Low High : Wnt3a - + hMSC YAP TAZ β-actin Byun et al. Supplementary Figure A B
description
Byun et al. Supplementary Figure 1. B. A. NIH3T3. MEF. hMSC. High. High. Low. Low. - +. - + - +. - + - +. : Wnt3a. YAP TAZ. TAZ (short). TAZ (long). β -actin. β -actin. Byun et al. Supplementary Figure 2. A. Cyt. Nuc. - +. - +. : Wnt3a. - PowerPoint PPT Presentation
Transcript of - + - +
- + - +
NIH3T3
Low High
TAZ (short)
β-actin
TAZ (long)
- + - +
MEF
Low High
: Wnt3a - +hMSC
YAP
TAZ
β-actin
Byun et al. Supplementary Figure 1
A B
Byun et al. Supplementary Figure 2
TAZ
Lamin B1
: Wnt3a - +Cyt.
- +Nuc.
α-tubulin
A
B
- + - + : Wnt3a
TAZ
pTAZ S89
TAZ
pTAZ S306.309
A BTAZ TAZ
+ MLTAZS89A+ ML
TAZ TAZ+ ML
TAZS306,309A+ ML
Byun et al. Supplementary Figure 3
- + : Wnt3aA B
TAZ
β-actin
- + : Wnt3a
C
- + : Wnt3a
- +
- +
- +
- + : Wnt3a
Byun et al. Supplementary Figure 4
1.0
1.52
Bp
Ti
- + + + + : Runx2
- - : Wnt3a
TAZ
β-actin
Bp Ti
A B
Byun et al. Supplementary Figure 5
Byun et al. Supplementary Figure 6
TAZTAZP
TAZTAZ
TAZTAZ
Wnt3a
Wnt3a
Nucleus
Cytosol
GSK3
Runx2
PP1A
Mst1/2
Lats1/2
P
14-3-3 TAZTAZP
P
