Respons imun pada bayi dan anak terhadap virus

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Keywords: innate immunity, adaptive immunity, viral infection

Transcript of Respons imun pada bayi dan anak terhadap virus

Respons imun pada Bayi dan Anak terhadap Virus

Prof DR Dr Ariyanto Harsono SpA(K)

Virus

MHC-IITh0

IL-12/ IL-1

Th-2

IL-1

TNF-β, IFN-γ

IL-2, IFN-γ

B-Cell

IL-4

IL-5

SEL PLASMASEL MEMORI

IL-6

IL-10

CTL MHC-I

I L-2 IFN-γ

SEL-NK

SEL-NK AKTIFFC-R

L

SEL ABNORMAL

SITOTOKSIN

SEL-LISIS

Sel Abnormal

Memory Cells

ADCC

Prof DR Dr Ariyanto Harsono SpA(K)

FASL Th.1

TCR

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http://images.google.com/imgres?imgurl=http://www.diabetes-research.org/Images/t-cell.jpg&imgrefurl=http://www.diabetes-research.org/immuno_research.htm&h=256&w=317&sz=41&tbnid=aFk2u2OGnrcJ:&tbnh=91&tbnw=112&start=21&prev=/images?q=T+cell&start=20&hl=id&lr=&sa=N

http://images.google.com/imgres?imgurl=http://www.diabetes-research.org/Images/t-cell.jpg&imgrefurl=http://www.diabetes-research.org/immuno_research.htm&h=256&w=317&sz=41&tbnid=aFk2u2OGnrcJ:&tbnh=91&tbnw=112&start=21&prev=/images?q=T+cell&start=20&hl=id&lr=&sa=N

http://images.google.com/imgres?imgurl=http://www.diabetes-research.org/Images/t-cell.jpg&imgrefurl=http://www.diabetes-research.org/immuno_research.htm&h=256&w=317&sz=41&tbnid=aFk2u2OGnrcJ:&tbnh=91&tbnw=112&start=21&prev=/images?q=T+cell&start=20&hl=id&lr=&sa=N

http://images.google.com/imgres?imgurl=http://www.miltenyibiotec.com/macs/products/human/b/imgs/b-cell-kit-2.gif&imgrefurl=http://www.miltenyibiotec.com/macs/products/human/b/911-51.htm&h=181&w=189&sz=23&tbnid=OjYG3iMyotIJ:&tbnh=91&tbnw=96&start=6&prev=/images?q=B+cell&hl=id&lr=&sa=G

http://images.google.com/imgres?imgurl=http://www.mcl.tulane.edu/classware/pathology/Krause/Blood/PlasmaCell1.jpg&imgrefurl=http://www.mcl.tulane.edu/classware/pathology/Krause/Blood/PlasmaCell.html&h=377&w=359&sz=110&tbnid=tnhnCvtLYyoJ:&tbnh=118&tbnw=113&start=4&prev=/images?q=plasma+cell&hl=id&lr=&sa=G

http://images.google.com/imgres?imgurl=http://www.staff.ncl.ac.uk/colin.brooks/NKcell.jpg&imgrefurl=http://www.staff.ncl.ac.uk/colin.brooks/research.html&h=240&w=240&sz=19&tbnid=GtmohuqgLlMJ:&tbnh=104&tbnw=104&start=44&prev=/images?q=NK+cell&start=40&hl=id&lr=&sa=N

Prof DR Dr Ariyanto Harsono SpA(K)

3Prof DR.dr. Ariyanto Harsono SpAK

Prof DR Dr Ariyanto Harsono SpA(K)

4Prof DR.dr. Ariyanto Harsono SpAK

Prof DR Dr Ariyanto Harsono SpA(K)

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6(J Allergy Clin Immunol 1999;118:124-6)

Th1

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virus

virus

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INNATE Immunity,,,,,

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Fc receptorbinding

Effectors mechanisms against extracellular pathogens

OPSONISATION

OPSONISATION Phagocytosis

Virus in extracellular space

Ab

+

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Effectors mechanisms against extracellular pathogens

COMPLEMENT Activation

Ab & COMPLEMENT

+

PhagocytosisComplement &Fc receptor binding

Lysis

Opsonisation

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Virus in extracellular space

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Gejala Klinik

Mononucleosis (Glandular Fever)

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Cytomegalovirus Infection

Congenital Cytomegalovirus Infection

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Wart

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Moluscum Contagiosum

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Herpes Simplex

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Condyloma acuminata

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Conjunctivitis

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Mumps

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Common cold

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Acrodermatitis enteropathica

Herpes Zoster

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Fifth disease (Erythema infectiosum)

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Measles

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Rubella

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Roseola Infantum

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Scarlet Fever

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varicella

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Variola

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Avian Flu

Siklus Avian flu Virus h5n1

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Swain Flu

Siklus Swain flu Virus A/H1 N1

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Singapore Flu

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Hongkong flu

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SARS

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HIV/AIDS

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Terimakasih52

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