2008

AntibioticsU 1200 γ-Substituted Bis(pivaloyloxymethyl)ester Analogues of Fosmidomycin and

FR900098. — The in vitro antimalarial activity of title compounds (VIII) is investigat-ed. However, the γ-substituted analogues display only weak to moderate efects against the chloroquine-sensitive strain 3D7 of Plasmodium falciparum. — (KURZ*, T.; BEHRENDT, C.; PEIN, M.; KAULA, U.; BERGMANN, B.; WALTER, R. D.; Arch. Pharm. (Weinheim, Ger.) 340 (2007) 12, 661-666; Inst. Pharm., Univ. Hamburg, D-20146 Hamburg, Germany; Eng.) — H. Haber

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