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JPET #143826 1 CHEMOTHERAPY-INDUCED CXC-CHEMOKINE/CXCR2 SIGNALING IN METASTATIC PROSTATE CANCER CELLS CONFERS RESISTANCE TO OXALIPLATIN THROUGH POTENTIATION OF NF-κB TRANSCRIPTION…
JPET #120709 1 Pharmacological Effects of Ephedrine Alkaloids on Human α1- and α2-Adrenergic Receptor Subtypes Guoyi Ma Supriya A Bavadekar Yolande M Davis Shilpa G Lalchandani…
By Kelompok A1 SISTEM SARAF PUSAT SISTEM SARAF MANUSIA SISTEM SARAF PERIFER SISTEM SARAF OTONOM ADRENERGIKA Simpatomometik atau adrenergika adalah zat-zat yang dapat menimbulkan…
JPET #167148 - 1 - Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison…
JPET #208108 1 The orally active opioid μδ dual agonist MGM-16 a derivative of indole alkaloid mitragynine exhibits potent anti-allodynic effect on neuropathic pain in…
JPET #180208 Previous exposure to Δ9-THC enhances locomotor responding to but not self-administration of amphetamine James J. Cortright, Daniel S. Lorrain, Jeff A. Beeler,…
JPET #116145 1 BIFUNCTIONAL ALKYLATING AGENT-INDUCED p53 AND NONCLASSICAL NUCLEAR FACTOR-KAPPA B NF-κB RESPONSES AND CELL DEATH ARE ALTERED BY CAFFEIC ACID PHENETHYL ESTER…
Asmah Nasser, M.D. Alpha blockers Beta blockers Alpha plus beta blockers Phenoxybenzamine (Non-competitive) Phentolamine (competitive) Ergot alkaloids: Ergotamine Ergotoxine…
Adrenergic Antagonists Adrenergic Antagonists These drugs act by either reversibly or irreversibly attaching to the receptor, thus preventing its activation by endogenous…
RECEPTORES ADRENERGICOS Adrenalina y Noradrenalina Tambien llamados Metabotropicos Receptores ligados a proteina G Tipos Existen varios tipos de receptores adrenérgicos…
PowerPoint PresentationNoradrenaline C Na+ Ca2+ Tyrosine direct (adrenaline, mesatone, isadrine) vaso- dilation glyco- genolysis platelets indirect action : ephedrine, dopamine
Structural Studies of the β2-Adrenergic Receptor Gs Complex Gerwin Westfield12 Soren Rasmussen3 Min Su1 Brian Kobilka3 and Georgios Skiniotis 12 1 Life Sciences Institute…
CNS Drugs 2006; 20 (5): 389-409REVIEW ARTICLE 1172-7047/06/0005-0389/$39.95/0 © 2006 Adis Data Information BV. All rights reserved. Mechanism of Action of Atypical Antipsychotic…
Adrenergic Agonists (Sympathomimetics) Characteristics of Adrenergic Agonists Most of adrenergic agonists are β-phenylethylamine derivatives. Substitution on either the…
JPET #149989 1 Coupling of β2-adrenoceptors to XLαs and Gαs: A new insight into ligand-induced G protein activation AI Kaya Ö Uğur ŞS Öner1 M Bastepe HO Onaran Ankara…
JPET #201616 1 Title Page A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared to…
JPET #152975 1 TITLE: GSI-953 (begacestat): A novel, selective thiophene sulfonamide inhibitor of APP γ-secretase for the treatment of Alzheimer’s disease Robert L. Martone,…
1. GIRIJA MAGANTI M.PHARM (PHARMACOLOGY) 2. Forty years ago, the binding of α-bungarotoxin was used to discover the muscle type nicotinic receptors in electric rays…
JPET #96909 Discriminative stimulus effects of γ-hydroxybutyrate (GHB): role of training dose. Wouter Koek, Weibin Chen, Susan L. Mercer, Andrew Coop, and Charles P. France…
1. Dr. K. R. Prabhakar, Resident. 2. CLASSIFICATION α-Adrenoceptor Antagonists Non-selective block α1 & α2SelectiveMiscellaneous •Ergot alkaloidsReversible Irreversible…