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Harvey L. Katzeff Merck Research Laboratories Rahway, New Jersey, USA An update on DPP-4 inhibitors in the management of Type 2 diabetes: potential roles in monotherapy and…
Bruce Buckingham, M.D., Roy W. Beck, M.D., P.H.D., Katrina J. Ruedy, M.S.P.H., Peiyao Cheng, M.P.H., Craig Kollman, P.H.D., Stuart A. Weinzimer, M.D., Linda A. DiMeglio,…
Type 2 diabetes via β-cell dysfunction in East Asian people Jeong Hyun Park MD PhD Department of Internal Medicine Busan Paik Hospital College of Medicine Inje University…
Human Mesenchymal Stem Cell Derived Exosomes Alleviate Type 2 Diabetes Mellitus by Reversing Peripheral Insulin Resistance and Relieving β‑Cell Destruction Yaoxiang Sun,†,‡,§…
Slide 1 Oral Agents in Management of Type 2 Diabetes Nemanja Stojanović Consultant Endocrinologist Queen’s Hospital, Romford Slide 2 We will talk about T2DM in general……
Adipocyte T cell TLR4 Hypertrophy Hypoxia ER stress Cell death IL-1R1 Ceramide Macrophage Fetuin-A TLR4 Fetuin-A Cytokines chemokines β-cell TLR4 Glucose TLR2 Free fatty…
PTPN2 regulates cytokine-induced β-cell death PTPN2 a candidate gene for type 1 diabetes modulates interferon-gamma- induced pancreatic beta-cell apoptosis Running title:…
Immunotherapy: Innovation Platform for Cancer Treatment Dr Suparerk Borwornpinyo Excellent Center for Drug Discovery Mahidol University Department of Biotechnology Faculty…
REVIEW Open Access The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus Sanabil Ali Hassan Ahmed1 Suraiya Anjum Ansari2 Eric P K Mensah-Brown1 and…
≥ 65% -cell defect Genetic Predisposition Environmental Factors Obesity Hyperinsulinemia with Normal Glucose Tolerance Impaired Glucose Tolerance Figure A1. Glucose…
Diabetes Mellitus Type II Beta Cell Failure in DM T2 signaling pathways implicated in β-cell failure Wnt Signaling Pathway Controls organismal growth and differentiation…
Pathogenesis of Type 1 DM Dr Abdulmoein Al-Agha Consultant Pediatric Endocrinologist King AbdulAziz University Hospital Jeddah Pathophysiology “Polygenic disorder” Pathogenesis…
Open Access Das and Panda J Diabetes Metab 2014 5:9 DOI: 1041722155-61561000432 Volume 5 • Issue 9 • 1000432J Diabetes Metab ISSN: 2155-6156 JDM an open access journal…
A Novel Combination Immunotherapy for Cancer by IL-13Rα2–Targeted DNA Vaccine and Immunotoxin in Murine Tumor ModelsModels Vaccine and Immunotoxin in Murine Tumor
RESEARCH ARTICLE Open Access Secondary resistance to immunotherapy associated with β-catenin pathway activation or PTEN loss in metastatic melanoma Jonathan A Trujillo1…
diabetes.diabetesjournals.org DIABETES, VOL. 62, NOVEMBER 2013 3645 NOVEMBER 2013 In This Issue of Diabetes Edited by Helaine E. Resnick, PhD, MPH Liu et al. Rhein protects…
Slide 1 Slide 2 Inside the Islet Exploring Issues in Type 2 Diabetes Role of Pancreatic Islets in Maintaining Normal Glucose Homeostasis Slide 3 Learning Objectives After…
Type 2 Diabetes – 2010 Robert J. Rushakoff, MD Professor of Medicine University of California, San Francisco [email protected] Hyperglycemia β hepatic glucose…
Research Article Open Access Nakamura et al., J Diabetes Metab 2011, 2:9 DOI: 10.4172/2155-6156.1000158 Volume 2 • Issue 9 • 1000158 J Diabetes Metab ISSN:2155-6156 JDM,…
1. Diabetes mellitusMIP Alejandro PorrasRamirez1 / Diciembre / 2011 2. DEFINICIÓN• Síndrome caracterizado por una alteraciónen el metabolismo de los hidratos decarbono,…