pNIC NICFF

NICLKB1 KD

- + + + SerumHrs: Metformin ( 5mM)

- + + + - + + +- - 1 6 - - 1 6 - - 1 6

LKB1

pAMPK (T172)

AMPK

pACC

α-Tubulin

50

50

75

50

75

250

50

Dupuy et al., Additional file 1: Figure S1