Supplementary Figure 1

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Supplementary Figure 1 WT KO Electroretinogram Body weight Vision Olfaction Hearing Motivation Prepulse inhibition Pain sensation A B C F G H I J Startle Preference [%] WT KO 0 25 50 75 Time [ms] Amplitude [μV] Latency to find food [s] WT KO 0 100 200 300 Latency [s] WT KO 0 5 10 15 20 dB Startle amplitude [au] 60 80 100 120 0 1 2 3 4 WT KO 1 2 3 4 40 60 80 100 Days Sucrose consumption [%] Am plitude [au] WT K O 0.0 0.5 1.0 1.5 2.0 2.5 Inhibition [%] 70 75 80 0 20 40 60 80 100 WT KO dB Time [s] Body weight [g] WT KO 0.0 2.5 5.0 7.5 10.0 12.5 15.0 17.5 D E Rotarod WT KO WT KO Amplitude (μV) Open field Periphery Intermediate Center 0 100 200 300 400 p=0.027 p=0.34 WT KO

description

WT. WT. WT. KO. KO. KO. Supplementary Figure 1. A. Body weight. B. Vision. C. Electroretinogram. D. Open field. Rotarod. E. p=0.34. 400. WT. WT. 17.5. 75. KO. KO. 15.0. 300. WT. 12.5. 50. KO. Body weight [g]. Preference [%]. Amplitude ( μ V ). Time [s]. 10.0. - PowerPoint PPT Presentation

Transcript of Supplementary Figure 1

Page 1: Supplementary Figure 1

Supplementary Figure 1

WTKO

ElectroretinogramBody weight Vision

Olfaction Hearing Motivation Prepulse inhibitionPain sensation

A B C

F G H I JStartle

Pre

fere

nce

[%

]

WT KO0

25

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Time [ms]

Am

plit

ude

[μ

V]

La

ten

cy t

o fin

d f

ood

[s]

WT KO0

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cy [

s]

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Sta

rtle

am

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1 2 3 440

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rose

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nsu

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e [a

u]

WT KO0.0

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Inh

ibiti

on

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70 75 800

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100WTKO

dB

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e [

s]

Bod

y w

eig

ht

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WT KO0.0

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D ERotarod

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ude

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Periphery Intermediate Center0

100

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p=0.34 WTKO

Page 2: Supplementary Figure 1

Supplementary Figure 2

Basic EPMAT

ime

[s]

Closed Center Open

0

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p=0.0002

WT

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EPM in darknessB

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s]

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D Open field

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o p

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s]

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C Open field

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s]

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E Open field

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ty [

mm

/s]

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F Vision

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WT KO0

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G

WT

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