Peginterferon-α
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Transcript of Peginterferon-α
Reactions 1387 - 4 Feb 2012
SPeginterferon-αOptic neuropathy: case report
A 28-year-old man started peginterferon-α 135 µg/weekfor chronic hepatitis C infection [route not stated]. Twomonth later, he developed a sudden onset left visual fielddeficit. Examination revealed a visual acuity of 20/30 in theright eye and 20/80 in the left eye, optic disk oedema,cotton wool spots, splinter haemorrhages, and visual fielddefects suggestive of inferior nerve fibre defects.Peginterferon-α was withdrawn, and he receivedmethylprednisolone. Following over 2 months oftreatment, his visual disturbances resolved andneurophysiological parameters normalised.Gokturk S, et al. A rare complication of interferon treatment: Optic neuropathy.Annals of Gastroenterology 24: 335, No. 4, 2011 - Turkey 803066515
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Reactions 4 Feb 2012 No. 13870114-9954/10/1387-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved