Patogenesis Osteoporosis Paska Menopause
1
menopauss Estrogen Bone marrow stronal cell dan osteobl Sel endot el osteokl as ↓ absorbsi kalsium ↓ absorbsi kalsium HIL-1. TNF-α, ↑ differensiasi dan muturasi osteoklas ↓TGF-β ↓ NO hipokalsi mia ↓ PTH ↑ resorbsi tulang osteoporo sis
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Transcript of Patogenesis Osteoporosis Paska Menopause
menopausse
Estrogen ↓
Bone marrow stronal cell dan sel mononuklear
osteoblas Sel endotel
osteoklas ↓ absorbsi kalsium
↓ absorbsi kalsium di ginjal
HIL-1. TNF-α, IL-6, M-CSF
↑ differensiasi dan muturasi osteoklas
↓TGF-β ↓ NOhipokalsimia
↓ PTH
↑ resorbsi tulang
osteoporosis
