Odigos Spoudon GR Final 13-14

7/18/2019 Odigos Spoudon GR Final 13-14

http://slidepdf.com/reader/full/odigos-spoudon-gr-final-13-14 1/208

"#$% & "#$'

( "#$%



!"#$%&'#( )*+,-. /"-0*12 : 32 . 4(5 . 6 . 78+,-89-0



ii

(+?2!&$#'%" !')2.2,-"

!"#$%&'()*$ +,-).*/(0#*$ 1&2%"3

4#0#, 5$&*,%03 6*$7$8',3 %,* 9)-)(*%03 ,

6o :7# ;7)<,-=&$>.$7"3-52%&"3

+,-).*/("#*$>.$7" , !&,82-, ,

4.? . 68100

"0)%(&$,'%" !')2.2,-"

www.mbg.duth.gr

*0"&$@$&')-

4"7: 25510/30610, 30612,30614

FAX: 25510/30613



iii

*)&')?$#),+

@)7'=,

"A5:;4BCD; +E79>A7FE;< GH;IJ 2012- 2013 vi

#)&$- ': 1),'%)- *0"&$@$&')- 1

($ !"#$%&'()'$ *+,)*'-("#'$ .&+%"- 2

!*2&A&B/" 3

!*$'%"/" 3

?,("8$&')3 +&$/B.*%$>

,6,A#'=)3

3

($ (#"#+ #$&'+%"- /'$0$1'+- %+' 1),)('%"- 4

@%$.C3 D=&E/"3 4

!*$'%"/"

!*=,%(*%C +&$/B.*%C

7

8

4$#)'3 ($E 4#0#,($3 – F&8,/(0&*, 10

?,-$-*/#C3 +&$.(E:*,%$> .&$8&2##,($3 @.$E=G- 13

!*,=*%,/')3 F*/,8B803 – F88&,H03 13

!*%,*$7$8"(*%2 F88&,H03 +&B($)(G- H$*("(G- 13

#)&$- '': *&$1&+##+ -*$2!3,

9)-*%I3 ,&:I3 ($E .&$8&2##,($3 14

+,&,%$7$>A"/" F<I(,/" 5,A"#2(B- 16

FE&B.,J%C @>/("#, 5)(,H$&23 %,* @E//G&)E/"3 +*/(B(*%G- 5$-2=B-

(ECTS)

16

+*/($.$*"(*%C ;-,7E(*%03 6,A#$7$8',3 17

+&$K.$AI/)*3 8*, ("- ;.$-$#0 +(E:'$E 18

L.$7$8*/#C3 6,A#$> +(E:'$E 19

!*.7B#,(*%0 F&8,/', 20

F-=)*%(*%C +&C8&,##, @.$E=G- ;%,="#,J%$> M($E3 2012-2013 22

*)&')?$#),$ #+."#+(3, 28

+)&*):C#)-$ L.$:&)B(*%G- 5,A"#2(B- 28



iv

+)&*):C#)-$ 5,A"#2(B- F.*7$803 123

#)&$- ''': @$'("('%+ .)#+(+ 188

!*=,%(*%2 @E88&2##,(, 189

N7)%(&$-*%2 5,A0#,(, 189

@'(*/" 189

@(I8,/" 189

!*%,*$7$8"(*%2 @'(*/"3-@(I8,/"3 190

L8)*$-$#*%0 +)&'A,7O" 190

!*)E%$7>-/)*3 /(*3 #)(,%*-0/)*3 190

6&,P)',- L.$(&$H')3 191

F%.,*=)E(*%2 +&$8&2##,(, 192

SOCRATES 192

ERASMUS

+&,%(*%0 2/%"/" ERASMUS

+&,%(*%0 2/%"/"

193

195

195

A00)- 2*"&)-')- 196

6*P7*$A0%" 196

9&,H)'$ !*,/>-=)/"3 196

9&,##,()*,%0 L.$/(0&*<" 197

?&"-'#)- *0"&$@$&')- 198

N .C7" ("3 ;7)<,-=&$>.$7"3 198

@E8%$*-B-')3 198

!*,#$-0 198

;<*$AI,(, 198

Q&0/*#, ("7IHB-, 199



v

"#)&$0$1'$ +%+!"#+K%$2 )($2- 2013-2014

)11&+@)- 9*, ($ :)*#)&*-C )<2#"-$ $* -)$)*/,8C#)-$* H$*("(I3 )88&2H$-(,* )-(C3 ("3 .&$A)/#',3 .$E

$&'R)(,* #) ,.CH,/" ($E L.$E&8$> FA-*%03 +,*=)',3 %,* 1&"/%)E#2(B- .

?)'#)&',$ )L+#",$

1. M-,&<" #,A"#2(B- 6/10/2013

2. S0<" #,A"#2(B- 15/1/2014 (*)

3. F<)(2/)*3 :)*#)&*-$> )<,#0-$E 20/1/2014- 7/2/2104 (*)

)+&',$ )L+#",$

4. M-,&<" #,A"#2(B- 10/2/2014(*)

5. S0<"#,A"#2(B- 3/6/2014(*)

6. F<)(2/)*3 ),&*-$> )<,#0-$E 10/6/2011-27/6/2014(*)

(*) $* "#)&$#"-')3 8*, %2A) )<2#"-$ I:$E- %,A$&'/()' ,.C (" @>8%7"($ ($E !"#$%&*()'$E +,-).*/("#'$E ,)-=I:)(,* -, E.2&<$E- (&$.$.$*0/)*3 $* $.$')3 ,-,%$*-G-$-(,* I8%,*&, ,.C (" 9&,##,()', ($E 4#0#,($3.

)*'-"#)-

+&1')--

!'+%$*)-

#+."#+(3,

!"# $%"&'()#*+% ,+-+$./"%0 1+231'*4# , "-(+/*3-%+560 +/57/"%0 5+% "&"*'/"%0 .

?)'#)&',$ )L+#",$

4"- 28" T%(BP&'$E FA-*%0 F.I()*$3

4"- 17" U$)#P&'$E F.I()*$3 +$7E():-)'$E

;.C ("- 23" !)%)#P&'$E IB3 %,* ("- 6" V,-$E,&'$E !*,%$.I3 Q&*/($E8I--B-

4"- 30" V,-$E,&'$E F$&(0 4&*G- V)&,&:G-

)+&',$ )L+#",$

4"- 18" 5,&('$E ?,A,&2 !)E(I&,

4"- 25" 5,&('$E FA-*%0 F.I()*$3

;.C ("- 14" ;.&*7'$E B3 %,* ("- 25" A.&*7'$E !*,%$.I3 +2/:,

4"- 1" 5,J$E +&B($#,8*2

4"- 14" 5,J$E ;.)7)EAI&B/" ;7)<,-=&$>.$7"3

4"- 9" V$E-'$E 4$E ;8'$E +-)>#,($3

4"- "#I&, .$E $&'R)(,* 8*, (" =*)<,8B80 (B- H$*("(*%G- )%7$8G-



ME!"# $

%&'$(&# )*+!","!$&#



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

2

.$ /,!$)#&."&$ *0("*&%.,!&$ 1#0),% (/*1)

1. /23454678

!" #$%"&'()*+" ,-.*/+0)1%+" 2'3&$4 +5'67$&* )" 1973 %* )" 8"%"7*)+&9 #+3)-:%- 87/93.

;."%30)$&* «#<=;>?@!A@;» /'"4 )+%1 )"B C+D90"C"B #$%9&'+)"B )"B EF5$'()$ . < 5+"(&$0$

)"B ,-.*/+0)$%("B *5'*6*+ 0)$. >"%")$.1 , )$. /'G)*6"B0- )$4 #+"+&$)+&14

,*'+CH'*+-4 E.-)"D+&14 =-&*5".(-4 &-+ 2'3&$4. !" #.,.2. -/")*D*()-+ -/9 !%1%-)- /"B

D*+)"B':"6. 0)$. I3.7$ , )$. >"%")$.1 , )$. ED*J-.5'"6/"D$ &-+ )$. ;'*0)+35- &-+

*(.-+ )- *J14 :

1. T%1%- 8"%+&14 , /"B D*+)"B':*( -/9 )" 1974 0)$. >"%")$.1 .

2. !%1%- ,"D+)+&K. =$L-.+&K. , /"B D*+)"B':*( -/9 )" 1974 0)$. I3.7$ .3. !%1%- <D*&)'"D9:G. =$L-.+&K. &-+ =$L-.+&K. M/"D":+0)K. , /"B D*+)"B':*(

-/9 )" 1975 0)$. I3.7$ .

4. !%1%- A/+0)1%$4 NB0+&14 E:G:14 &-+ E7D$)+0%"6 (!.A.N.E.E.), /"B D*+)"B':*( -/9

)" 1984 0)$. >"%")$.1 .

5. !%1%- @-)'+&14 , /"B D*+)"B':*( -/9 )" 1985 0)$. ED*J-.5'"6/"D$ .

6. ,-+5-:G:+&9 !%1%- #$%")+&14 A&/-(5*B0$4 , /"B D*+)"B':*( -/9 )" 1986 0)$.

ED*J-.5'"6/"D$ .

7. A/+0)$%K. *&/-(5*B0$4 0)$. ,'"0L"D+&1 $D+&(- , /"B D*+)"B':*( -/9 )" 19870)$. ED*J-.5'"6/"D$ .

8. !%1%- @0)"'(-4 &-+ A7."D":(-4 , /"B D*+)"B':*( -/9 )" 1991 0)$. >"%")$.1 .

9. !%1%- =$L-.+&K. ,*'+F3DD".)"4 , /"B D*+)"B':*( -/9 )" 1995 0)$. I3.7$

10. !%1%- ADD$.+&14 N+D"D":(-4 , /"B D*+)"B':*( -/9 )" 1995 0)$. >"%")$.1 .

11. !%1%- >"+.G.+&14 #+"(&$0$4 &-+ ,"D+)+&14 */+0)1%$4 , /"B D*+)"B':*( -/9 )" 1996

0)$. >"%")$.1 .

12. !%1%- E'L+)*&)9.G. =$L-.+&K. , /"B D*+)"B':*( -/9 )" 1999 0)$. I3.7$ .

13.!%1%-

;+&"."%+&K.

*/+0)$%K.

,/"B

D*+)"B':*(

-/9

)"

19990)$.

>"%")$.1

.

14. !%1%- E:'")+&14 E.3/)BJ$4 , /"B D*+)"B':*( -/9 )" 1999 0)$. ;'*0)+35-.

15. !%1%- #-0"D":(-4 , #+-L*('+0$4 ,*'+F3DD".)"4 &-+ NB0+&K. ,9'G. , /"B

D*+)"B':*( -/9 )" 1999 0)$. ;'*0)+35-.

16. !%1%- =$L-.+&K. ,-'-:G:14 &-+ #+"(&$0$4 , /"B D*+)"B':*( -/9 )" 2000 0)$.

I3.7$ .

17. !%1%- ODG00K. , N+D"D":(-4 &-+ ,"D+)+0%"6 ,-'*BJ*(.+G. PG'K. , /"B D*+)"B':*(

-/9 )" 2000 0)$. >"%")$.1 .

18. !%1%- ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 , /"B D*+)"B':*( -/9 )" 1999 0)$.

ED*J-.5'"6/"D$ .



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

3

/29:;878

< "':3.G0$ &-+ $ D*+)"B':(- )"B #.,.2 , 5+H/".)-+ -/9 )+4 5+-)3J*+4 )"B 8.

1268/82 «O+- )$ 5"%1 &-+ D*+)"B':(- )G. E.K)-)G. A&/-+5*B)+&K. @5'B%3)G. (EA@)»,

9/G4 )'"/"/"+17$&* %* )" 8. 2083/92 &-+ )". 8. 4009/2011. =* F30$ )$. /'"-.-C*'7*(0- &*(%*.$ ."%"7*0(- &37* ,-.*/+0)1%+" B/"5+-+'*()-+ 0* RL"DH4 &-+

!%1%-)-. ;+ RL"DH4 «&-D6/)"B. H.- 06."D" 0B::*.K. */+0)$%K. , H)0+ K0)* .-

*J-0C-D(S*)-+ $ -.-:&-(- :+- )$. */+0)$%".+&1 *JHD+J$ -DD$D*/(5'-0$ )"B4 &-+ "

-.-:&-("4 :+- )$. H'*B.- &-+ )$ 5+5-0&-D(- 0B.)".+0%94».

>37* RL"D1 B/"5+-+'*()-+ 0* !%1%-)-. !" !%1%- «-/")*D*( )$ F-0+&1 D*+)"B':+&1

-&-5$%-T&1 %".35- &-+ &-D6/)*+ )" :.G0)+&9 -.)+&*(%*." %+-4 */+0)1%$4. !" /'9:'-%%-

0/"B5K. )"B !%1%-)"4 "5$:*( 0* H.- *.+-(" /)BL("».

!" EA@ 5+"+&*()-+ )" RB%F"6D+" , )". ,'6)-.$ &-+ )$ R6:&D$)". < RL"D1 5+"+&*()-+ -/9 )".

&"0%1)"'- , )$. &"0%$)*(- &-+ )$ O*.+&1 RB.HD*B0$ . !" !%1%- 5+"+&*()-+ -/9 )". ,'9*5'"

&-+ )$ O*.+&1 RB.HD*B0$ .

2. )<=8>94:?@ *4976A2;9B, C<5D:E?@

!" /'"0G/+&9 /"B *':3S*)-+ 0)- EA@ 5+-&'(.*)-+ 0)+4 *J14 &-)$:"'(*4:

• #+5-&)+&9 &-+ A'*B.$)+&9 ,'"0G/+&9 (#A,). UD- )- %HD$ #A, HL"B. 5+5-&)"'+&9

5(/DG%- &-+ 5+-&'(.".)-+ 0* )H00*'+4 F-7%(5*4: >-7$:$)H4 , E.-/D$'G)H4 >-7$:$)H4 ,

A/(&"B'"+ >-7$:$)H4 &-+ VH&)"'*4.

• A+5+&9 A':-0)$'+-&9 #+5-&)+&9 ,'"0G/+&9 (AA#@,). ,*'+D-%F3.*+ )"B4 5+5-0&3D"B4

JH.G. :DG00K. , 0L*5+30*G. , &.D/. (&D35"4 @) &-+ )" /'"0G/+&9 /"B -0L"D*()-+ %* )"

*':-0)$'+-&9/*C-'%"0%H." 5+5-&)+&9 H':" /"B 0B.(0)-)-+ &-)3 &6'+" D9:" 0)$

5+*J-:G:1 *':-0)$'+-&K. &-+ &D+.+&K. -0&10*G. (&D35"4 @@).

• A+5+&9 !*L.+&9 A':-0)$'+-&9 ,'"0G/+&9 (A!A,). ,-'HL*+ *J*+5+&*B%H.*4 )*L.+&H4

*':-0)$'+-&H4 B/$'*0(*4 :+- )$. B/"0)1'+J$ )"B *&/-+5*B)+&"6 , *'*B.$)+&"6 &-+

*C-'%"0%H."B H':"B )"B !%1%-)"4.

• #+"+&$)+&9 ,'"0G/+&9. ,*'+D-%F3.*+ )"B4 5+"+&$)+&"64 B/-DD1D"B4 9DG. )G.

F-7%(5G. /"B B/3:".)-+ 0)$ :*.+&1 5+"(&$0$ )"B E.A.@.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

4

.$ .!,!0 !$#&0),% C&$+$'&0% )0& '"(".&),%

1. %;9AF@ GE4H78@

!" !%1%- ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 (!=QO) )"B #,2 +5'67$&* )" 1999 (,.#.208/99). T" !=QO D*+)"B':*( -/9 )" -&-5$%-T&9 H)"4 2000-2001 %* 0 &"/9 )$.

&-DD+H':*+- &-+ )$. /'"-:G:1 )G. 0B:&*&'+%H.G. &D35G. )G. F+"*/+0)$%K. %*

H%C-0$ 0)". !"%H- )$4 M:*(-4.

O+ -/9C"+)"+ )"B !%1%-)"4 ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 )"B #$%"&'()*+"B

,-.*/+0)$%("B 2'3&$4 %* F30$ )+4 :*.+&H4 &-+ )+4 *J*+5+&*B%H.*4 :.K0*+4 /"B

-/H&)$0-. &-)3 )$ 5+3'&*+- )G. 0/"B5K. )"B4 56.-.)-+ .- -/-0L"D"6.)-+ -)"%+&3 1

0* 0B.*':-0(- %* */+0)1%".*4 3DD$4 *+5+&9)$)-4 , 0* 9D" )" C30%- )"B :.G0)+&"6

-.)+&*+%H."B )G. F+"*/+0)$%K..

!" :.G0)+&9 -.)+&*(%*." )G. -/"C"()G. )"B !%1%-)"4 ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 ,

G4 *& )$4 C60*G4 )G. F+"*/+0)$%K. , *(.-+ -/9 )- /DH". 5B.-%+&3 , &-+ 5+-'&K4

5+*B'B.9%*.- &-+ *J*D+009%*.- &-+ -0&*()-+ */-::*D%-)+&3 %* "/"+-51/")*

*':-0+-&1 0LH0$ , &-7K4 &-+ %* )$ %"'C1 /-'"L14 B/$'*0+K. , 0B%F"BDK. &-+

:.G%-)*60*G..

;+ -/9C"+)"+ )"B !%1%-)"4 ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 -0L"D"6.)-+

*/-::*D%-)+&3 %* &37* -.)+&*(%*." , /"B -C"'3 0)$. /'"HD*B0$ , 0)$. D*+)"B':(- &-+

0)$. *JHD+J$ )G. H%F+G. "':-.+0%K. &-+ &37* %"'C14 SG14 *. :H.*+ , 0)" /*'+F3DD". ,

0)"B4 -F+")+&"64 /-'3:".)*4 /"B 0L*)(S".)-+ %* )$ SG1 , &-+ 0)+4 *C-'%":H4 )G.

/-'-/3.G.

A.5*+&)+&3 , $ */-::*D%-)+&1 /-'"B0(- )G. -/"C"()G. )"B !%1%-)"4 ="'+-&14 Q+"D":(-4

&-+ O*.*)+&14 &-7(0)-)-+ */+F*FD$%H.$ 0)"B4 *J14 , -.-C*'9%*."B4 )"%*(4

*/-::*D%-)+&14 5'-0)$'+9)$)-4:

! R)$. A&/-(5*B0$ , 0* 5$%90+- &-+ +5+G)+&3 *&/-+5*B)+&3 +5'6%-)- 9DG. )G.

F-7%(5G. , %* -.)+&*(%*." 5+5-0&-D(-4 )$. F+"D":(- &-+ :*.*)+&1 , &-7K4 &-+ &37*

3DD" :.G0)+&9 -.)+&*(%*." /"B 0L*)(S*)-+ %* )+4 F+"*/+0)1%*4.

! R)$. W'*B.- /3.G 0* &37* :.G0)+&9 -.)+&*(%*." /"B B/3:*)-+ 0)". *B'6)*'" )"%H- )G. F+"*/+0)$%K. &-+ , $ "/"(- *()* HL*+ -%+:K4 7*G'$)+&1 -*/+0)$%".+&1

&-)*67B.0$ , %$ 0B.5*9%*.$ %* *%/"'+&"64 0&"/"64 , *()* /'""'(S*)-+ :+-

F+"%$L-.+&1 *C-'%":1 , &-+ 5+*J3:*)-+ %* /'G)"F"BD(- &-+ L'$%-)"59)$0$

5$%90+G. 1 +5+G)+&K. C"'HG. , 0* *'*B.$)+&3 &H.)'- , +.0)+)"6)- , +5'6%-)- &-+

*':-0)1'+- /"B -.1&"B. 0)" 5$%90+" 1 0* +5+K)*4 , &-7K4 &-+ 0* -'%95+*4

5+*B76.0*+4 , B/"5+*B76.0*+4 1 )%1%-)- *7.+&K. , *B'G/-T&K. 1 5+*7.K.

"':-.+0%K. &-+ +5+G)+&K. */+L*+'10*G..



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

5

! R)" #$%90+" &-+ @5+G)+&9 !"%H- , 0* B/$'*0(*4 M:*(-4 ( ."0"&"%*(- , ."%-'L(*4 &-)

0* &'-)+&H4 B/$'*0(*4 (ANA! , M:*+"."%+&H4 B/$'*0(*4 &-), 0* 5+-:.G0)+&3

*':-0)1'+- &-+ *)-+'*(*4 , %* -.)+&*(%*.- , 9/G4:

! < */+D":1 )G. F+"D":+&K. BD+&K.-5*+:%3)G. &-+ :*.*)+&"6 BD+&"6 &-+ )G.

%*795G. *JH)-0$4 &-+ -.3DB014 )"B4 , " HD*:L"4 )$4 /"+9)$)-4 )G. -.-D60*G. ,o HD*:L"4 )$4 *C-'%":14 )G. -'LK. "'714 *':-0)$'+-&14 /'-&)+&14 &-+

-0C3D*+-4 , $ *'%$.*(- &-+ $ -J+"D9:$0$ )G. -/")*D*0%3)G. )G. -.-D60*G.

/"B /'-:%-)"/"+"6.)-+ 0* F+"-.-DB)+&3 *':-0)1'+- , 9/G4: %"'+-&14 F+"D":(-4 ,

:*.*)+&14 , F+"L$%*(-4 , -."0"F+"D":(-4 , -+%-)"D":(-4 , +0)"/-7"D":(-4 ,

%+&'"F+"D":(-4 , &B))-'"D":(-4 &-+ &B))-'":*.*)+&14.

! < */+D":1 &-+ " HD*:L"4 *':-0)$'+-&K. 5+*':-0+K. /"B -C"'"6. 0)$.

-.-/-'-:G:1 &-+ 0)". HD*:L" 1 0)$ 5+-)1'$0$ :-%*)K. 1 *%F'6G. 1 -'LH:".G.

&B))3'G. &-+ "+ *C-'%":H4 )"B4.

! < */+D":1 &-+ " HD*:L"4 )$4 /"+9)$)-4 )G. -.)+5'-0)$'(G. (-.)+0K%-)- ,

'-5+"T09)"/- &D/) &-+ )G. *C-'%":K. )"B4 0)+4 F+"*/+0)1%*4 , &-7K4 &-+ 0* &37*

3DD$ 0L*)+&1 */+0)1%$ , 0)$. "/"(- $ L'10$ )G. /-'-/3.G -.)+5'-0)$'(G.

&'(.*)-+ -.-:&-(- 0* &3/"+" F+"D":+&9 060)$%-.

! < "':3.G0$ &-+ D*+)"B':(- %"B0*(G. CB0+&K. */+0)$%K. , F+"*/+0)$%K. , CB0+&14

+0)"'(-4 , SG"D":+&K. &-+ F")-.+&K. &1/G..

! < 5*+:%-)"D$X(- , $ *&/9.$0$ *':-0)$'+-&K. %*D*)K. &-+ F+"-.-D60*G. &-7K4

&-+ $ 5+*.H':*+- *DH:LG. /"B -C"'"6. 0)"B4 F+")+&"64 &-+ -F+")+&"64

/-'3:".)*4 )"B "+&"0B0)1%-)"4 , 0)+4 0LH0*+4 %*)-J6 )"B4 , 0)$. */(5'-0$ /"B

-0&"6. 0* -B)"64 "+ F+"%$L-.+&H4 &-+ 3DD*4 -.7'K/+.*4 5'-0)$'+9)$)*4 , &-+

0)$. -J+"D9:$0$ )G. 0B0)$%3)G. /*'+F-DD".)+&14 5+-L*('+0$4.

! < *&/9.$0$ *':-0)$'+-&K. -.-D60*G. &-+ F+"-.-DB)+&K. %*D*)K. /"B -C"'"6.

0)" F+"D":+&9 HD*:L" )$4 /"+9)$)-4 )G. B53)G. , )"B *53C"B4 )"B -H'- &-+ )G.

)'"C(%G. , 0)$ 5+-L*('+0$ &-+ /'"0)-0(- )G. 7-D300+G. /3'&G. , B5'"F+9)"/G. ,

/")-%K. , D+%.K. &-+ &37* 3DD"B B53)+."B 0L$%-)+0%"6 , )$4 -)%90C-+'-4 , )G.

/30$4 C60*G4 -/"FD1)G. &-+ -/"''+%%3)G. , )G. 7"'6FG. , )G. 5".10*G. &-+ )G.

&'-5-0%K.. A/(0$4 $ *&/9.$0$ *':-0)$'+-&K. -.-D60*G. &-+ F+"-.-DB)+&K.

%*D*)K. -/"&-)30)-0$4 )"B /*'+F3DD".)"4.! < */+0)$%".+&1 H'*B.- &-+ *C-'%":1 )*L.+&K. 0)". )"%H- )$4 M/"D":+0)+&14

Q+"D":(-4 &-+ )$4 Q+"/D$'"C"'+&14 , &-7K4 &-+ 0)". )"%H- )$4 #"%+&14 Q+"D":(-4 ,

+5+-()*'- :+- )". 0L*5+-0%9 C-'%3&G. &-+ 3DDG. F+"5'-0)+&K. "B0+K..

! < */+D":1 , " 0L*5+-0%94 &-+ " HD*:L"4 )$4 *C-'%":14 F+")*L."D":+&K. %*795G.

&-+ %*795G. :*.*)+&14 %$L-.+&14 0)$. 5+-)1'$0$ &-+ -J+"/"($0$ :*.*)+&K.

/9'G. (F+"/"+&+D9)$)-), 0)"B4 )"%*(4 )$4 F+"%$L-.(-4 C-'%3&G. , )$4

F+"%$L-.(-4 5+-:.G0)+&K. /'"T9.)G. , )$4 :*G':(-4 , )$ 4 &)$.")'"C(-4 &-+ )$4

-D+*(-4. ; HD*:L"4 :*.*)+&3 )'"/"/"+$%H.G. "':-.+0%K. , C-'%3&G. ,

5+-:.G0)+&K. &-+ .*"C-.K. "B0+K. &-+ /'"T9.)G. , /"B L'$0+%"/"+"6.)-+ 1 /-'3:".)-+ 0)"B4 )"%*(4 )$4 :*G':(-4 , )$4 &)$.")'"C(-4 , )$4 -D+*(-4 , &-7K4 &-+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

6

0)+4 F+"%$L-.(*4 C -'%3&G. , )'"C(%G. , &-DDB.)+&K. , &D/. A/(0$4 $ 0B%%*)"L1

0)$ 5+-5+&-0(- /-'-:G:14 )G. /-'-/3.G /'"T9.)G..

! < */+0)$%".+&1 H'*B.- , $ /-'"L1 0B%F"BDK. &-7K4 &-+ $ *C-'%":1 )*L.+&K.

0)". )"%H- )G. F+"*/+0)$%K..

! ;+ /)BL+"6L"+ )"B !%1%-)"4 ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 -.-D-%F3."B. )$. *B76.$ , B/":'3C".)-4 -)"%+&3 1 0B.B/":'3C".)-4 %* 3DD"B4 *+5+&*B%H."B4

*/+0)1%".*4 , 0)- &3)G7+:

! E/")*DH0%-)- , %*DH)*4 &-+ /+0)"/"+$)+&3 -.-D60*G. F+"D":+&"6 &-+ :*.*)+&"6

BD+&"6 &-7K4 &-+ &D+.+&K. 1 3DDG. 5"&+%K. /"B 5+*J3:".)-+ in vitro 1 in vivo.

A/(0$4 /'-:%-)":.G%"06.*4 /"B /'""'(S".)-+ :+- 5+"+&$)+&1 1 +-)'"5+&-0)+&1

L'10$ &-+ F-0(S".)-+ 0)$. */*J*':-0(- F+"D":+&K. /-'-%H)'G. &-+ +5+-()*'-

)"B :*.*)+&"6 BD+&"6.

! ,+0)"/"+$)+&3 *DH:L"B *C-'%":14 )G. -'LK. ;'714 A':-0)$'+-&14 ,'-&)+&14 &-+

E0C3D*+-4 0* 5+-5+&-0(*4 /"B 3/)".)-+ )"B :.G0)+&"6 -.)+&*+%H."B )G.

F+"*/+0)$%K..

! E/")*DH0%-)- , %*DH)*4 &-+ /+0)"/"+$)+&3 /"+9)$)-4 &-+ -0C3D*+-4 :+- )$.

-.7'K/+.$ &-+ 5$%90+- B:*(-.

! =*DH)*4 &-+ -J+"D9:$0$ "+&"0B0)$%3)G. &-+ /+0)"/"($0$ /*'+F-DD".)+&K. &-+

"+&"D":+&K. */+/)K0*G. &-7K4 &-+ /D$7B0%+-&H4 %*DH)*4.

! ,'")30*+4 /"B B/"F3DD".)-+ 0)$. AB'G/-T&1 W.G0$ 1 3DD". "':-.+0%9 1 &'3)"4 ,

0L*)+&3 %* */+5")"6%*.- /'":'3%%-)- H'*B.-4 &-+ )*L."D":+&14 -.3/)BJ$4

/"B *%/(/)"B. 0)" *B'6)*'" /*5(" )G. Q+"*/+0)$%K..

!- */-::*D%-)+&3 5+&-+K%-)- )G. /)BL+"6LG. )"B !=QO /*'+:'3C".)-+ -.-DB)+&3 0)"

,'"*5'+&9 #+3)-:%- 158/1.10.2009 /"B 5$%"0+*6)$&* 0)" NA> E199/1.10.2009.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

2. /29:;878 ;<2 /2E<;=2;F *4976A2;F

*4F?E49@ :

?-C-1D R-.5-D)S9/"BD"4 , E.-/D$'G)14 >-7$:$)14

!$D. 25510-30622

email: [email protected]

'4<DD<=?:< :

*49I7=3D?J9@ '4<DD<=?:<@

E0$%-&9/"BD"4 #$%1)'+"4

!$D. 25510-30610

Fax: 25510-30613

e-mail [email protected]

*4976A2;F '4<DD<=?:<@

O'$:"'+35"B ADH.$ !$D. 25510-30612

K B'+3&$ R"C(- !$D. 25510-30642

V+)0+&3&$ ?9$ !$D. 25510-30613

!0"%/-."65$4 RG)1'+"4 !$D. 25510-30611



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

8

!"#$%&"%' ()*+,-&"%' .)/012"%' &/+ 3456 ( 478- !(.)

9,/:$ 6,10&"%' ;,&"%*<:*,/ 3-87=1,/

(%1#"%'> 25510)email

?$@-A-&7>

!"#$%&'($% )*'++" ,-+-./(0 30666 [email protected]

!"%#$1"#' 23+-&453 6/$731-8" 30618 [email protected]

;,$28-)1&7> ?$@-A-&7>

,#39$#8$% !"#8" !$#/"(0 6/$&$98" -

:+"5.%;/"(0 6/$&$98" 30657 [email protected]

<4==" !"#8" 6/$&$98" <%..'#$% 30661 [email protected]

>"+?"&.@45$%&$A

B"="0& !$#/"(0 6/$&$98" 30622 [email protected]

C%&"(."(8?$%

<*+D."+.8+" E31-8" F#9"+/(G+ H+GD-*+ 30663 [email protected]

E2<%/+)/" ?$@-A-&7>

:9/"+/'+ !5o94A !$#/"(0 6/$&$98" 1- I1="D3

D.3 J$10 !"(#$1$#8*+ 30668 [email protected]

,"&'+3A :&I;/$A !$#/"(0 6/$&$98" 1- I1="D3

D.3 1-."9*90 D31'.*+ 30634 [email protected]

,&%(4A K/(4&"$A Y 5$&$9/D./(0 ("/ J$1/(0

6/$&$98" 30620 [email protected]

<$%#($%.'A )*'++3A H="#1$D1I+3 6/$.-7+$&$98" 30633 [email protected]

!5$%($%L'&"

>*.3#8" !$#/"(0 ,-+-./(0 30632 [email protected]

2"55' :9&"M"

C%D/$&$98" F#9"+/D1G+ 1-

I1="D3 D.$%A !$#/"($NA

!37"+/D1$NA J#'D3A

C"#1'(*+

30625 [email protected]

2'D7$% 2-#/D.I#" ,-+-./(0 2&3O%D1G+ 30658 [email protected]

>('L?3A ,-G#9/$A !$#/"(0 6/$&$98" 30626 [email protected]

C"(0A ,/"++$N&3A ,-+-./(0 :+O#G5$% ("/

2-/#"1"./(G+ !$+.I&*+ 30628 [email protected]

E".@'(3 !"#8" ,-+/(0 6/$&$98" 1- I1="D3 D.3

@*$&$98" ("/ .3+ $/($&$98" 30636

[email protected]

E&87&/" :/(".-#8+3 !$#/"(0 :+$D$L/$&$98" 30630 "[email protected]



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

9

("#"%' ()A$0&-)"$%' !"#$%&"%' .)/012"%' (((!B.)

9,/:$ E"#"%'&-&$ 3-87=1,/

(%1#"%'> 25510)email

J#.>."+-&$N?3

E#%D$L"&'+.* 6/$&49$A 30385 [email protected]

("#"%' 3*C,"%' ()A$0&-)"$%' .)/012"%' ((3(.)

9,/:$ ("#"%'&-&$ 3-87=1,/

(%1#"%'> 25510)email

J#. !-."&&/+$N E#%D$N&" 6/$&49$A 30641 [email protected]

J#. !"&'.$A >*.0#3A 6/$&49$A 30384 [email protected]

9,/:$ E"#"%'&-&$ 3-87=1,/

(%1#"%'> 25510)email

D7%&/)*>

<".D'+3 :/(".-#8+3 2#*.-P+/(0 E31-8" 30635 [email protected]

<-?#'(" :/(".-#8+3 J/?"(./(0 .*+ 6/$-5/D.31G+ [email protected]



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

0

3. .9D?:@ =9H .DPD<=9@ - "4><7=P42<

!" !%1%- ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 HL*+ "':-.G7*( (-)6/G4) 0)"B4 *J14 )"%*(4:

.9DK<@ C<72;QJ -H72;QJ "A27=8DQJ, C29O8D?:<@ ;<2 C29=?OJ9L9>:<@

!KL8 C<5D:E< 'J67=2;F 0J=2;?:D?J9

1. =-B'"%-'3 ,$.*D9/$ >-7$:1)'+- Q+"L$%*(-

2. NBD-&)-&(5"B

>G.0)-.)(.- E.. >-7$:1)'+- P$%*(- ;':-.+&K. A.K0*G.

3 >"B'&"B)34 @G3..$4 A/. >-7$:$)14 AC-'%"0%H.$ Q+")*L."D":(-

4. >-)03.$ E+&-)*'(.$ VH&)"'-4 ,'G)*T.+&1 P$%*(-

"4><7=P429 =9H .9DK<

• A':-0)1'+" ;':-.+&14 Q+"D":+&14 P$%*(-4 &-+ P$%*(-4 NB0+&K. ,'"T9.)G. (H)"4

(5'B0$4 2003)

.9DK<@ !942<;P@ ;<2 RA9L9>27=2;P@ C29L9>:<@

!KL8 C<5D:E< 'J67=2;F 0J=2;?:D?J9

1. R-.5-D)S9/"BD"4 ?-C-1D E.. >-7$:$)14 ="'+-&1 Q+"D":(-

2. ODB&94 8+&9D-"4 A/. >-7$:$)14 M/"D":+0)+&1 &-+ #"%+&1

Q+"D":(-

3. ,-//3 E:D-Y- A/. >-7$:1)'+-

NB0+"D":(- %* H%C-0$

0)"B4 %"'+-&"64

%$L-.+0%"64 5'30$4

C-'%3&G.

4. PD(LD+- E+&-)*'(.$ A/. >-7$:1)'+- ="'+-&1 E."0"F+"D":(-

5. O-D3.$4 EDHJ+"4 A/. >-7$:$)14

="'+-&1 Q+"D":(- %* H%C-0$

0)$ 5+-&B))-'+&1

0$%-)"59)$0$

"4><7=P429 =9H .9DK<

• O".+5+-&14 W&C'-0$4 , ="'+-&14 #+3:.G0$4 &-+ R6:L'".G. 2*'-/*B)+&K. =H0G.

(H)"4 (5'B0$4 2002)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

.9DK<@ !942<;P@, )H==<42;P@, 0J<A=HS2<;P@ C29L9>:<@ ;<2

C29D942<;QJ "N<4D9>QJ

=HD$ Q-7%(5- O.G0)+&9 E.)+&*(%*."

1. O'$:"'("B =-'(- E.. >-7$:1)'+- ="'+-&1 Q+"D":(--

E.-/)BJ+-&1 Q+"D":(-

2. >9CC- =-'(- A .. >-7$:1)'+- Q+"D":(- >B))3'"B

3. R&3F5$4 O*K':+"4 A/. >-7$:$)14 ="'+-&1 Q+"D":(-

4. E:+-.+3. =/":94 A/. >-7$:$)14 ="'+-&1 Q+"D":(- %* H%C-0$

0)$ 5"%1 %-&'"%"'(G.

"4><7=P42< =9H .9DK<

• ="'+-&14 Q+"D":(-4 E.3/)BJ$4 &-+ ="'+-&14 8*B'"F+"D":(-4 (H)"4 (5'B0$4 2006)

• ="'+-&14 >B))-'+&14 Q+"D":(-4 , >B))-'+&"6 >6&D"B &-+ ,'G)*"%+&14 (H)"4

(5'B0$4 2006)

.9DK<@ '?J?=2;P@, '9J2E26D<=2;P@ ;<2 %H7=8D<=2;P@ $4><J27DQJ

!KL8 C<5D:E< 'J67=2;F 0J=2;?:D?J9

1. M-'"BD3&"B @G3..- >-7$:1)'+- O*.*)+&1

2. ,30L"B ,*'+0)H'- A/. >-7$:1)'+- O*.*)+&1 ,D$7B0%K.

3. N-&14 O+-.."6D$4 A/. >-7$:$)14

O*.*)+&1 E.7'K/"B %*

H%C-0$ 0)$.

>B))-'":*.*)+&1

4. =/"B&"BF3D- RG)$'(- A/. >-7$:1)'+- ="'+-&1 O*.*)+&1

5. P-)S3&$ =-'(- A/. >-7$:1)'+- O*.+&1 Q+"D":(- %* H%C-0$ 0)$ ZG"D":(- &-+ ;+&"D":(-

"4><7=P429 =9H .9DK<

• O*.*)+&14 ,D$7B0%K. &-+ AJHD+J$4 (H)"4 (5'B0$4 2002)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

2

4. )<J9J27DF@ *49A=HO2<;9B *49>43DD<=9@ %A9HEQJ

4.1 /2<E2;<7:?@ "27<>6>P@ -">>4<NP@

< *+0-:G:1 0)" !%1%- ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 /'-:%-)"/"+*()-+ %H0G

)"B 0B0)1%-)"4 )G. O*.+&K. A+0$)$'(G. AJ*)30*G. 1 %*)3 -/9 &-)3)-J$ )G.

/)BL+"6LG. 3DDG. RL"DK. %* F30$ &-)-)-&)1'+*4 *J*)30*+4 /"B 5+*.*':"6.-)+ -/9 )"

!%1%-. < /'90&D$0$ &-+ $ *::'-C1 )G. /'G)"*)K. C"+)$)K. :(.*)-+ %H0- 0* /'"7*0%(-

/"B &-7"'(S*)-+ &37* L'9." %* -/9C-0$ )"B M/"B':*("B ,-+5*(-4 , 2'$0&*B%3)G. ,

,"D+)+0%"6 &-+ E7D$)+0%"6 &-+ -.-&"+.K.*)-+ -/9 )- %H0- %-S+&14 *.$%H'G0$4. !-

5+&-+"D":$)+&3 /"B &-D"6.)-+ .- &-)-7H0"B. "+ C"+)$)H4 /"B HL"B. *+0-L7*( %* F30$

)- -/")*DH0%-)- )G. O*.+&K. AJ*)30*G. *(.-+ )- -&9D"B7-:

4.2 /2;<29L9>8=2;3 ">>4<NP@ *46=9?=QJ -92=8=QJ

• E()$0$ :+- *::'-C1 (5(5*)-+ -/9 )" !%1%-).

• !()D"4 -/9DB0$4 1 /)BL("B 1 -/"5*+&)+&9 )"B 0L"D*("B )"B "/"("B -/"C"()$0* 1

."%(%G4 */+&B'G%H." 1 -&'+FH4 -.)(:'-C" )"B )()D"B (%/"'*( .- CH'*+ &-+ )"

/'G)9)B/" ).

• M/*67B.$ #1DG0$ «9)+ 5*. *(.-+ *::*:'-%%H."4 0* 3DD$ RL"D1 1 !%1%- EA@ 1 !A@.».

• 6 NG)":'-C(*4 )6/"B E0)B."%+&14 !-B)9)$)-4.

• #*D)("

E0)B."%+&14

!-B)9)$)-4

(NG)")B/(-

).

• E.)(:'-C" */+&B'G%H." )$4 F*F-(G0$4 /'90F-0$4 0)$. 3F37%+- *&/-(5*B0$ (:+- )"B4

*/+)BL9.)*4 )"B *.+-("B VB&*("B).

• A3. 1)-. *::*:'-%%H."4 0* 3DD" EA@ )" E/"C"+)1'+9 )"B.



ME!"# $$

)!"%!-..- #)"/01'



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

4

1. !"#$%&' ()*&' +,- .),/)0112+,'

!" #$"%&'()*+, #$,-$*..* /%"'012 &"' !345 6(7) 8(70)*8&79 :;87) 0)7<212

%$"&=%>2. ?*&; &* 0=" %$1&* 6&@ &>2 8%"'012 &"'A ") B")&@&6A 7C")+7)12"2&*) .7 &)A

:*8)+6A 622")7A +*) *$(6A &>2 3"$)*+12 4)"7%)8&@.12 +*<1A +*) .7 &)A 8=-($"27A

.7<,0"'A +*) &7(2)+6A. ?*&; &" &$9&" +*) &6&*$&" 6&"A ") B")&@&6A 7.:*<=2"'2 8&@

.7D6&@ &@A 3"$)*+EA 4)"D"-9*A +*) 5727&)+EA +*<1A 7%98@A +*) &>2 7B*$."-12 &"'A. F)

B")&@&6A 6("'2 &@2 7'+*)$9* 2* %*$*+"D"'<E8"'2 &)A 8=-($"27A +*) &)A *2*0',.727A

&;87)A 87 7C7)0)+7'.62* %709* .68* *%, &* .*<E.*&* 7%)D"-EA %"' %$"8B6$"2&*). G21

@ 0)%D>.*&)+E (%&'()*+E ) 7$-*89* %"' %$*-.*&"%")79&*) +*&; &" &7D7'&*9" 7C;.@2"

&>2 8%"'012 , *%"&7D79 %$>&,&'%@ 7$7'2@&)+E 7$-*89* +*) 7+%"279&*) 8&"

#*27%)8&E.)" E 87 G$7'2@&)+"=A B"$79A.

H 0);$+7)* &>2 8%"'012 8&" !345 "$9I7&*) 87 &6887$* *+*0@.*J+; 6&@ (8

7C;.@2*). !" *+*0@.*J+, 6&"A *$(9I7) &@2 1@ /7%&7.:$9"' +;<7 ($,2"' +*) DE-7) &@2 31@

K'-"=8&"' &"' 7%,.72"'. ?;<7 *+*0@.*J+, 6&"A %7$)D*.:;27) 0=" 7C;.@2*: &"

(7).7$)2, +*) &" 7*$)2,. 37 :;8@ &" ;$<$" 25 &"' L. 1268/82 +;<7 7C;.@2" %7$)D*.:;27)

&"'D;()8&"2 13 7:0".;07A -)* 0)0*8+*D9* +*) 2 -)* 7C7&;87)A. K2 -)* "%")"20E%"&7 D,-"

" *$)<.,A &>2 7:0".;0>2 0)0*8+*D9*A %"' %$*-.*&"%")E<@+*2 87 62* .;<@.* 792*)

.)+$,&7$"A *%, &)A 07+*&$79A , &" .;<@.* <7>$79&*) ,&) 072 0)0;(<@+7 +*) 072

7C7&;I7&*) , &'(,2 07 7C6&*8E &"' 792*) ;+'$@ +*) " :*<.,A 072 '%"D"-9I7&*)-)* &@2

*%"2".E &"' &9&D"' 8%"'012./&* 7C;.@2* K -G 0)0;8+"2&*) .,2" '%"($7>&)+; .*<E.*&* &* "%"9* @ 572)+E

/'26D7'8@ &"' !.E.*&"A <7>$79 *%"D=&>A *%*$*9&@&* -)* &@2 7%)8&@."2)+E +*&;$&)8@

&"' 3"$)*+"= 4)"D,-"' - 5727&)8&E . ?*&; 8'26%7)* " B")&@&EA 792*) '%"($7>.62"A 2* &*

%*$*+"D"'<E87) ,D* 7%)&'(1A %$"+7).62"' 2* %;$7) %&'(9". /&" /!’ +*) 8&" M’ 7C;.@2"

7+&,A *%, &* '%"($7>&)+; .*<E.*&* 0)0;8+"2&*) +*) .*<E.*&* 7%)D"-EA *%, &* "%"9* "

B")&@&EA 792*) '%"($7>.62"A 2* 7%)D6C7) "+&11. !* .*<E.*&* 7%)D"-EA (>$9I"2&*) 87

2 ".;07A – *'&; &"' %709"' 3"$)*+EA 4)"D"-9*A & 5727&)+EA +*) *'&; &"' %709"'

#*)0*->-)+12 – N)0*+&)+EA (:D %*$*+;&> «#)8&"%")@&)+, N)0*+&)+EA +*) #*)0*->-)+EA G%;$+7)*A»). #$"+7).62"' ") B")&@&6A 2* %;$"'2 %&'(9" <* %$6%7) *%, &* 8 .*<E.*&*

7%)D"-EA (4 *2; 7C;.@2") %"' ($7);I"2&*) , &"'D;()8&"2 &* 6 (3/7C;.@2") 2* 792*) &"'

%709"' 3"$)*+EA 4)"D"-9*A & 5727&)+EA. O8") B")&@&6A 7%)<'."=2 2* %;$"'2 &"

%)8&"%")@&)+, 0)0*+&)+EA 7%;$+7)*A <* %$6%7) "3$34&,# &>2 6 .*<@.;&>2 3"$)*+EA

4)"D"-9*A & 5727&)+EA 2* %;$"'2 +*) &* 6 .*<E.*&* %*)0*->-)+12 (7%98@A 3/7C;.@2").

F) B")&@&6A 792*) '%"($7>.62") 2* 0@D18"'2 &* .*<E.*&* 7%)D"-EA %"' %$"&9<72&*) 2*

%*$*+"D"'<E8"'2 *$(E &"' /!’ +*) &"' M’ 7C*.E2"'. K *&; &" H ’ 7C;.@2" ") B")&@&6A

1 O) B")&@&6A %"' 7)8E(<@8*2 &* 6&@ 2012 +*) 2013 *+"D"'<"=2 &" *2&98&")(" %$,-$*..* 8%"'012 .7 &)A &$"%"%")E87)A %"' %7$)-$;B"2&*) 8&)A .7&*:*&)+6A 0)*&;C7)A (:D. %*$*+;&>)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

5

/'-:%-)"/"+"6. #+/DG%-)+&1 A':-0(- (FD. /-'-&3)G).

.9 *27=9A928=2;F 'JQ7?6J U?2427D9B ,/R

R)" /D-(0+" )"B /'":'3%%-)"4 0/"B5K. "+ C"+)$)H4 HL"B. )$. *B&-+'(- .-

-/"&)10"B. ,+0)"/"+$)+&9 O.K0*G. P*+'+0%"6 </M /-'-&"D"B7K.)-4 */+)BLK4

)H00*'- %-71%-)- /"B *%/(/)"B. 0)" /*5(". #6" -/9 )- %-71%-)- -B)3 *(.-+

B/"L'*G)+&3 *.K )- 3DD- 56" */+D":14.

.9 *27=9A928=2;F /2E<;=2;P@ ;<2 *<2E<>6>2;P@ "A34;?2<@

R)" .H" ,'9:'-%%- R/"B5K. )"B !%1%-)"4 ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14

/*'+D-%F3.*)-+ %+- "%35- %-7$%3)G. 5+5-&)+&14 &-+ /-+5-:G:+&14. !- %-71%-)- -B)3

HL"B. *+0-L7*( 0)" ,'9:'-%%- R/"B5K. /'"&*+%H."B )" !=QO .- *.-'%".+0)*( %* )". 8.

3848/2010, /-'.2 3'7 , 2 (NA> E[/71) 06%CG.- %* )" "/"(" $ /+0)"/"+$%H.$ /-+5-:G:+&1 &-+ 5+5-&)+&1 */3'&*+- -/")*D*( /DH". -.-:&-(- /'"\/97*0$ 5+"'+0%"6 0)$.

*&/-(5*B0$ . < /-+5-:G:+&1 &-+ 5+5-&)+&1 */3'&*+-4 &-)"LB'K.*)-+ %H0G )$4

/-'-&"D"67$0$4 "&)K (8) %-7$%3)G. )"B /*5("B , *.0G%-)G%H.G. 0)" ,'9:'-%%-

R/"B5K. )"B !%1%-)"4. R)"B4 C"+)$)H4 /"B "D"&D$'K."B. )- 0B:&*&'+%H.- %-71%-)-

%* */+)BL(- , -/".H%*)-+ )" ,+0)"/"+$)+&9 #+5-&)+&14 &-+ ,-+5-:G:+&14 A/3'&*+-4. ;

F-7%94 )"B ,+0)"/"+$)+&"6 /'"&6/)*+ G4 " %H0"4 9'"4 )G. F-7%K. )G. 0B:&'&'+%H.G.

%-7$%3)G.. R)" !%1%- ="'+-&14 Q+"D":(-4 &-+ O*.*)+&14 56" -/9 )- 8 %-71%-)- *(.-+

B/"L'*G)+&3 *.K )- B/9D"+/- 6 */+D":14. U+ C"+)$)H4 /"B */+7B%"6. .- -/"&)10"B. )" /+0)"/"+$)+&9 5+5-&)+&14 */3'&*+-4 /'H/*+ ?A2ALK9J )G. 6 %-7$%3)G. ="'+-&14

Q+"D":(-4 & O*.*)+&14 .- */+DHJ"B. &-+ )- 6 %-71%-)- /-+5-:G:+&K. (FD /-'-/3.G).

2. *<4<;9L9B5878 - "SK=<78 !<58D3=6J

< /-'-&"D"67$0$ )G. %-7$%3)G. *(.-+ /'"-+'*)+&1 , ]0)90" D9:G ) $4 C60*G4

)"B -.)+&*+%H."B )"B !=QO *(.-+ -/-'-()$)$ :+- )$. &-)-.9$0$ )$4 6D$4 &-+ )$.

*&/9.$0$ )G. *':-0)$'+-&K. &-+ C'".)+0)$'+-&K. -0&10*G.. < /'"0HD*B0$ )G.

C"+)$)K. 0)+4 *':-0)$'+-&H4 1 C'".)+0)$'+-&H4 -0&10*+4 *(.-+ B/"L'*G)+&1 &-+ 5*.

*/+)'H/*)-+ &-%(- -/"B0(-. !*&%$'+G%H.- 5+&-+"D":$%H.$ -/KD*+- *.94 *':-0)$'("B

1 C'".)+0)$'("B *(.-+ 5B.-)9. .- -.-/D$'G7*( &-)3 )". /'"0C"'9)*'" )'9/" &-+

06%CG.- %* )$. &'(0$ )"B 5+530&".)-. < */+)BL14 /-'-&"D"67$0$ /+0)"/"+*()-+ -/9 )$

0C'-:(5- )"B *':-0)$'("B 0)" Q+FD+3'+" R/"B5K. )"B C"+)$)1 . !- Q+QD+3'+- R/"B5K.

/'H/*+ .- */+5*+&.6".)-+ 0* &37* *J*)-0)+&1 . R* /*'(/)G0$ /"B 5*. CH'"B. )$.

-.)(0)"+L$ 0C'-:(5- $ 0B%%*)"L1 )"B C"+)$)1 0)+4 *J*)30*+4 )"B %-71%-)"4 5*.

*/+)'H/*)-+. !- Q+FD+3'+- R/"B5K. 0BDDH:".)-+ -.- H)"4 &-+ 0C'-:(S".)-+ 0*

$%*'"%$.(*4 /"B -.-&"+.K.".)-+. A(.-+ B/"L'HG0$ )"B &37* C"+)$)1 .- CH'*+ )"



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

6

Q+FD+3'+" R/"B5K. 0)+4 $%*'"%$.(*4 -B)H4 , &-7K4 &-+ .- )" /-'-D3F*+. R* /*'(/)G0$

/"B 5*. )$'$7"6. "+ $%*'"%$.(*4 &-)37*0$4 , )- Q+FD+3'+- R/"B5K. 5*. :(.".)-+ 5*&)3.

;+ *J*)-0)+&H4 /*'("5"+ *(.-+ )'*+4: )"B @-."B-'("B-N*F'"B-'("B , )"B @"B.("B &-+

)"B R*/)*%F'("B. R)+4 56" /'K)*4 *J*)-0)+&H4 /*'+95"B4 *J*)3S".)-+ %9." )-

%-71%-)- )G. -.)(0)"+LG. *J-%1.G. (5$D-51 )"B L*+%*'+."6 *J-%1."B )". @-."B3'+" -

N*F'"B3'+" &-+ )"B *-'+."6 )". @"6.+"). >-)3 )$. *J*)-0)+&1 /*'("5" )"B R*/)*%F'("B

*J*)3S".)-+ 9D- )- %-71%-)- &-+ )G. 56" *J-%1.G..

< &D(%-&- F-7%"D":(-4 0* &37* %37$%- *(.-+ -/9 0 HG4 10. A/+)BL14 7*G'*()-+ $

*JH)-0$ 9)-. " F-7%94 )"B C"+)$)1 *(.-+ )"BD3L+0)". /H.)* (F30$ */+)BL(-4). < )*D+&1

F-7%"D":(- 0* H.- %37$%- *.5HL*)-+ .- *(.-+ -/")HD*0%- %+-4 0B."D+&14 *JH)-0$4 1

0B.*&)(%$0$4 */+%H'"B4 -J+"D":10*G. (:'-/)H4 1 /'"C"'+&H4 *J*)30*+4 , /'-&)+&H4

*J*)30*+4 , 0B%%*)"L1 0)$. *&/-+5*B)+&1 5+-5+&-0(- , /-'"B0(-0$ *':-0+K. :+- *+5+&3

7H%-)- , &D/.). < F-7%"D":(- )"B C"+)$)1 0* &37* %37$%- &-7"'(S*)-+ -/9 )". 5+530&".)- " "/"("4 "':-.K.*+ &-)3 )$. &'(0$ )"B )+4 :'-/)H4 , /'"C"'+&H4 *J*)30*+4 1 3DD"B

)6/"B *J*)30*+4.

=* F30$ )" 3'7'" 24, ,-'3:'-C"4 3 )"B 8. 1268/92 0 * &37* *J-%$.+-(" %37$%-

-.)+0)"+L*( 0B:&*&'+%H."4 -'+7%94 5+5-&)+&K. %".35G.. < 5+5-&)+&1 %".35- -.)+0)"+L*(

0* %(- *F5"%-5+-(- K'- 5+5-0&-D(-4 */( H.- *J3%$." /'"&*+%H."B /*'( -B)")*D"64

5+5-0&-D(-4 %-71%-)"4 &-+ 0* %+- %HL'+ )'*(4 *F5"%-5+-(*4 K'*4 5+5-0&-D(-4 1

*J30&$0$4 */( H.- *J3%$." :+- )" B/9D"+/" *&/-+5*B)+&9 H':" (*':-0)1'+- ,

C'".)+0)1'+-) 06%CG.- %* 0L*)+&1 -/9C-0$ )$4 O*.+&14 RB.HD*B0$4 )"B !%1%-)"4. R)"

,'9:'-%%- R/"B5K. "'(S*)-+ &-+ " *D3L+0)"4 -'+7%94 5+5-&)+&K. %".35G. /"B -/-+)*()-+ :+- )$ D1X$ )"B /)BL("B ="'+-&"6 Q+"D9:"B – O*.*)+0)1 .

=* )$. "D"&D1'G0$ )"B /'"/)BL+-&"6 /'":'3%%-)"4 0/"B5K. "+ C"+)$)H4 )"B

!%1%-)"4 ="'+-&14 Q+"D":(-4 & O*.*)+&14 HL"B. :

! -/"&)10*+ )+4 7*%*D+K5*+4 7*G'$)+&H4 :.K0*+4 0)" /*5(" )G.

Q+"*/+0)$%K. &-+ *(.-+ 0* 7H0$ .- /*'+:'3C"B. )+4 F-0+&H4 H.."+*4 &-+

-'LH4 /"B )+4 5+H/"B..

! -/"&)10*+ *J*+5+&*B%H.*4 7*G'$)+&H4 :.K0*+4 0)" /*5(" )$4 ="'+-&14

Q+"D":(-4 & O*.*)+&14 &-+ )G. *C-'%":K. )"B4 &-+ *(.-+ 0* 7H0$ .-

-.-D6"B. 0* F37"4 )+4 H.."+*4 &-+ )+4 -'LH4 /"B )+4 5+H/"B..

! -/"&)10*+ )+4 F-0+&H4 :.K0*+4 &-+ *':-0)$'+-&H4 5*J+9)$)*4 )$4

!*L."D":(-4 )G. Q+"*/+0)$%K. &-7K4 */(0$4 &-+ *J*+5+&*B%H.*4

:.K0*+4 &-+ *':-0)$'+-&H4 5*J+9)$)*4 0)". )"%H- )$4 !*L."D":(-4 )$4

="'+-&14 Q+"D":(-4 & O*.*)+&14 "+ "/"(*4 )"B4 */+)'H/"B. .-

0)-5+"5'"%10"B. 0* &D35"B4 &-+ */-::HD%-)- 0L*)+&3 %* )+4

Q+"*/+0)1%*4 (9/G4 /*'+:'3C".)-+ 0)$. *.9)$)- 5 )"B /-'9.)"4) 1 .-

/'"LG'10"B. 0* %*)-/)BL+-&H4 0/"B5H4.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

! -.-/)6J*+ 5*J+9)$)*4 -/")(%$0$4 -/")*D*0%3)G. , -.3/)BJ$4

*/+0)$%".+&K. B/"7H0*G. &-+ /*+'-%-)+&"6 0L*5+-0%"6 -&"D"B7K.)-4

)$. */+0)$%".+&1 %H7"5".

! -.-/)6J*+ 5*J+9)$)*4 :'-/)14 &-+ /'"C"'+&14 /-'"B0(-0$4

*/+0)$%".+&K. 5*5"%H.G. &-+ +5*K..

3. To "H46A<I;F %B7=8D< !?=<N943@ ;<2 %H77Q4?H78@

*27=6=2;QJ !9J3E6J (European Credit Transfer System, ECTS)

!" AB'G/-T&9 R60)$%- =*)-C"'34 E&-5$%-T&K. =".35G. (ECTS) *(.-+ H.-

060)$%- L"'1:$0$4 &-+ %*)-C"'34 -&-5$%-T&K. %".35G. , )" "/"(" -/"0&"/*( 0)$

5+*B&9DB.0$ )$4 -&-5$%-T&14 -.-:.K'+0$4 %H0G -/")*D*0%-)+&K. %$L-.+0%K.

&-7"D+&14 +0L6"4. ,'"FDH/*+ H.-. &K5+&- "'714 /'-&)+&14 :+- )$. "':3.G0$ )$4

-&-5$%-T&14 -.-:.K'+0$4 F30*+ )$4 5+-C3.*+-4 )G. /'":'-%%3)G. 0/"B5K. &-+ )G.

*/+590*G. )G. 0/"B5-0)K..

!" ECTS 5*. 'B7%(S*+ -B)9 &-7-B)9 )" /*'+*L9%*." , )$ 5"%1 1 )$. -.)+0)"+L(- )G.

-&-5$%-T&K. /'":'-%%3)G. , 5*5"%H."B 9)+ /'9&*+)-+ :+- 7H%-)- )G. "/"(G. $ /"+9)$)-

/'H/*+ .- &-7"'(S*)-+ -/9 )- (5+- )- /-.*/+0)1%+- , &-)3 )$. &-)3')+0$ )G.

/'":'-%%3)G. 0/"B5K.. ;+ /+0)G)+&H4 %".35*4 /"B -/"5(5".)-+ 0* &37* %37$%- ,

/'-&)+&1 30&$0$ , /)BL+-&1 *':-0(- *&C'3S"B. )". C9')" *':-0(-4 /"B -/-+)*( &37*

-B)")*DH4 *&/-+5*B)+&9 0B0)-)+&9 0)"+L*(" :+- .- */+)*BL7"6. "+ -.)+&*+%*.+&"( 0)9L"+ /"B */+5+K&".)-+ , 0* 0LH0$ %* )". 0B."D+&9 C9')" *':-0(-4 /"B -/-+)*()-+ :+-

)$. "D"&D1'G0$ *.94 -&-5$%-T&"6 H)"B4 /D1'"B4 C"()$0$4. ; C9')"4 *':-0(-4 /"B

-/-+)*()-+ .- &-)-F3D*+ &37* C"+)$)14 &-)3 )$ 5+3'&*+- *.94 -&-5$%-T&"6 H)"B4

/D1'"B4 C"()$0$4 *&)+%3)-+ &-)3 %H0" 9'" 0* 1500-1800 K'*4 *':-0(-4 &-+ +0"5B.-%*(

%* 60 /+0)G)+&H4 %".35*4. To !=QO *C-'%9S*+ )" 060)$%- %*)-C"'34 &-+ 0B00K'*B0$4

/+0)G)+&K. %".35G. -/9 )" -&-5$%-T&9 H)"4 2008-2009 &-+ L"'$:*( , -/9 )" 2012, %* )"

/H'-4 )G. 0/"B5K. *&)94 )"B ,)BL("B , )" ,-'3')$%- #+/DK%-)"4 (Diploma Supplement)

0)$. ADD$.+&1 &-+ 0)$. E::D+&1 ODK00-.

4. To *27=9A928=2;F 0J<LH=2;P@ C<5D9L9>:<@ (Transcript

of Records)

!" ,+0)"/"+$)+&9 E.-DB)+&14 Q-7%"D":(-4 /+0)"/"+*( )+4 */+590*+4 )"B C"+)$)1

%* )$. -.-DB)+&1 &-)-:'-C1 )G. %-7$%3)G. /"B /-'-&"D"67$0* &-+ *J*)30)$&* , )+4

5+5-&)+&H4 &-+ /+0)G)+&H4 %".35*4 /"B 0B:&H.)'G0* , )"B4 F-7%"64 /"B HD-F* &-+ )"B4

-.)(0)"+L"B4 F-7%"64 )"B *B'G/-T&"6 0B0)1%-)"4 %*)-C"'34 &-+ 0B00K'*B0$4

/+0)G)+&K. %".35G.. !" ,+0)"/"+$)+&9 *&5(5*)-+ 0)$. *DD$.+&1 &-+ -::D+&1 :DK00- -/9

)". -'%95+" 0B.)".+0)1 ECTS. !" !=QO *&5(5*+ /+0)"/"+$)+&3 -/9 )" H)"4 2012 /"B



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

8

!"#$%&'( (! !)&*&+,&-( &+ *&+,.,/0 )&' 1+23#4.2!( ,& !5!6.7!859 /,&0 2008-2009.

: 5!,.;&"+&)&$.2. ,<( 1)+6921<( ,<( 1)+,'#9(,<( *&+,.,=( ;$(1,!+ 71 >?2. ,.(

!59@&'4. 2#1,+53 5@$7!5! >!47&@&;$!0 ,&' 1'"<)!85&- 2'2,37!,&0 71,!*&"?0 5!+

2'22="1'2.0 )+2,<,+5=( 7&(?6<(:

!"#$%& ECTS '%(%()* +%,)-)./ 0%1 (1/2#34 50,)1678/%1/ )%/ 9"#$*

!"#$*4 A :," )%14 ;"<=)5>%14 50,)17*/)54 (5 0%(%()* 10%

!"#$*4 B :," )%14 50*$5/%14 50,)17*/)54 (5 0%(%()* 25%

!"#$*4 C :," )%14 50*$5/%14 50,)17*/)54 (5 0%(%()* 30%

!"#$*4 D :," )%14 50*$5/%14 50,)17*/)54 (5 0%(%()* 25%

!"#$*4 E :," )%14 )5<51)"&%14 50,)17*/)54 (5 0%(%()* 10%

: 5!,.;&"+&)&$.2. ,<( 1)+6921<( ,<( !)&,'#9(,<( *&+,.,=( 1$(!+ . !59@&'4.

!"#$%& ECTS '%(%()* +%,)-)./ 0%1 ?5/ 50,)1678/%1/ )%/ 9"#$*

!"#$*4 FX @/50,)1724 5AB)"(- - C>5,8D%/)", %>,($B/54 ";*$- 95<),.(5,4,

.()5 /" $0%>5& /" ;>,#5& 50,)1724 - 50&?%(-

!"#$*4 F @/50,)1724 5AB)"(- - C>5,8D%/)", %1(,.?5,4 50,0<B%/

95<),.(5,4.

5. '>%E0%#B(5,4 6," @0%/%$2 ')17&%1

@0">"&)-)54 0>%E0%#B(5,4 6," )- <2F- )%1 0)17&%1:

!. A)+,'#30 1B/,!2. 2,& 2-(&@& ,<( ')&#"1<,+5=( 7!4.7?,<( ,&' C"&;"?77!,&0

D)&'6=(.

>. A)+,'#30 1B/,!2. 2,! 7!437!,! 1)+@&;30 (4 7!437!,! 2,& DE’ 5!+ 4 7!437!,! 2,& F’

1B?7.(&).

;. A)+,'#30 &@&5@3"<2. ,.0 G+)@<7!,+530 A";!2$!0. : 15)9(.2. G+)@<7!,+530 A";!2$!0

1$(!+ ')&#"1<,+53 ;+! ,&'0 *&+,.,/0.

: 2'(6"&73 ,&' 2'(9@&' ,<( !(<,/"< )"&H)&4/21<( !(,+2,&+#1$ 2,.

2';5/(,"<2. 2'(&@+5? 155 6+6!5,+5=( 7&(?6<( )&' +2&6'(!7&-( 71 240 )+2,<,+5/0

7&(?610 ECTS.

I+! ,&( ')&@&;+279 97<0 ,&' >!47&- ),'#$&' @!7>?(&(,!+ ')9J. 79(& &+

6+6!5,+5/0 7&(?610 , 2-7*<(! 71 ,+0 6+!,?B1+0 ,.0 )!". 5 ,&' ?"4"&' 14 ,&' K.

3374/2005 5!+ 2-7*<(! 71 ,! !(!*1"971(! 2,&( )!"9(,! L!(&(+279 D)&'6=(.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

9

: )!"!5&@&-4.2. ,<( *"&(,+2,."$<( 5!+ ,<( 1";!2,."$<( 1(90 7!437!,&0 1$(!+

')&#"1<,+53 ;+! ,&'0 *&+,.,/0 , 15,90 1?( &"+2,1$ 6+!*&"1,+5? !)9 ,&( !(,$2,&+#&

6+6?25&(,!. M+ @1),&7/"1+10 21 9 ,,+ !*&"? ,&'0 9"&'0 )!"!5&@&-4.2.0 ,<( !(<,/"<

15)!+61',+5=( 6"!2,."+&,3,<( 5!4&"$%&(,!+ 5!,? )1"$),<2. !)9 ,&'0 !(,$2,&+#&'0

6+6?25&(,10.

6. G0%<%6,($*4 !"#$%= ')17&%1

D-µ*<(! µ1 ,.( N)&'";+53 O)9*!2. P3/2166/1987 (QAL 308 PR), ;+! ,&( ')&@&;+2µ9 ,&'

>!4µ&- ,&' ),'#$&' )&@@!)@!2+?%1,!+ & >!4µ90 5?41 µ!43 µ!,&0 1)$ /(! 2'(,1@12,3 , &

&)&$&0 &(&µ?%1,!+ 2'(,1@12,30 >!"-,.,!0 ,&' µ!43 µ!,&0 , 5!+ , !5&@&-4<0 ,& ?4"&+2µ!

,<( 1)+µ/"&'0 ;+(&µ/(<( 6+!+"1$,!+ µ1 ,& ?4"&+2µ! ,<( 2'(,1@12,=( >!"-,.,!0 9@<(

,<( µ!4. µ?,<(.

M+ 2'(,1@12,/0 >!"-,.,!0 1$(!+ 1,0, 1,5 5!+ 2,0 5!+ ')&@&;$%&(,!+ <0 1B30:

-S!43 µ!,! µ1 1 3 2 6+6!5,+5/0 µ&(?610 /#&'( 2'(,1@12,3 >!"-,.,!0 1.0.

-S!43 µ!,! µ1 3 3 4 6+6!5,+5/0 µ&(?610 /#&'( 2'(,1@12,3 >!"-,.,!0 1.5.

-S!43 µ!,! µ1 )1"+229,1"10 !)9 4 6+6!5,+5/0 µ&(?610 /#&'( 2'(,1@12,3 >!"-,.,!0 2.

M >!4790 ),'#$&' 6$61,!+ 71 !5"$>1+! 615?,&' 5!+ 5'7!$(1,!+ !)9 5.0 7/#"+ 5!+ 10.0. D,&

),'#$& !(!;"?*1,!+ 5!+ & #!"!5,."+2790:

L!@=0 (>!4790 ),'#$&' 5.0 – 6.49)

T$!( 5!@=0: (>!4790 ),'#$&' 6.5 - 8.49)

U"+2,! (>!4790 ),'#$&' 8.5 – 10.00)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

20

7. H,0<3$"),;2 I>6"(&" (HI)

7.1 D5&)90 ,.0 GA

D5&)90 ,.0 6+)@<7!,+530 1";!2$!0 1$(!+ . 1B&+51$<2. ,&' *&+,.,3 71 ,.(

1)$@'2. 1(90 1)+2,.7&(+5&- 4/7!,&0 , . )"&2!"7&;3 ,&' 2,& )1"+>?@@&( ,&'

1";!2,."$&' S&"+!530 P+&@&;$!0 – I1(1,+530 5!+ . !)95,.2. 17)1+"$!0 2,&( ,"9)&

2';;"!*30 7+!0 1)+2,.7&(+530 1";!2$!0.

: VA 1$(!+ )1+"!µ!,+53 , 1"1'(.,+53 1";!2$! µ1 2,9#& ,.( )"!5,+53 1B?25.2. 21

1";!2,."+!5/0 ,1#(+5/0 , 2,.( &";?(<2. )1+"!µ!,+5=( )"<,&59@@<( , 2,.( 9B'(2. ,.0

5"+,+530 +5!(9,.,!0 ,&' *&+,.,3 , 2,.( 5!,!(9.2. ,.0 1)+2,. µ&(+5? ,15µ."+<µ/(.0

1"1'(.,+530 )"!5,+530 , 2,. #"32. >+>@+&;"!*$!0 , 2,.( !(?@'2. -!B+&@9;.2.

!)&,1@12µ?,<( 5!+ 2,. 2';;"!*3 !',&,1@&-0 1)+2,. µ&(+5&- 51+µ/(&'.

• : 6+)@<7!,+53 1";!2$! 1$(!+ ')&#"1<,+53 .

• : 15)9(.2. ,.0 GA 6+!"51$ /B+ 73(10 5!+ )"!;7!,&)&+1$,!+ 5!,? ,& : 1B?7.(&.

• : GA +2&6'(!71$ 71 20 G.S. (30 7&(?610 ECTS)

: ;@=22! 2';;"!*30 ,.0 6+)@<7!,+530 1";!2$!0 1$(!+ . 1@@.(+53 , !@@? 21

&"+27/(10 )1"+),=21+0 . 2';;"!*3 1$(!+ 6'(!,9( (! )"!;7!,&)&+.41$ 5!+ 2,.(

!;;@+53 .

: VA 15)&(1$,!+ !) 2,& &+51$& Eµ3 µ! µ1 1)$>@1J. µ1@=( VAC ,&' Eµ3 µ!,&0 ESPI 3 21 ?@@&

&µ&1+6/0 Eµ3 µ! OAW 2,.( A@@?6! 3 2,& 1B<,1"+59 5!+ >) 21 !(!;(<"+2µ/(& (412µ&41,. µ/(&)

A"1'(.,+59 W(2,+,&-,& , 2,.( A@@?6! 3 2,& 1B<,1"+59.

: 15)9(.2. VA 2,& 1B<,1"+59 µ)&"1$ (! 1)+,1'#41$ !) µ/2< ,&' A'"<)!85&-

C"&;"?µµ!,&0 D<5"?,.0 (Socrates/Erasmus - >@. D#1,+53 A(9,.,!) > ) µ1,? !)9 6+µ1"1$0

2'µ*<($10 µ1 &)&+!63)&,1 #="! (!59µ! 5!+ 15,90 A'"<)!8530 X(<2.0).

M+ *&+,.,/0 )&' 15)&(&-( GA 1$(!+ ')&#"1<µ/(&+ (! !5&@&'4&-( ,& )"9;"!µµ!

1";!2$!0 )&' ,&'0 ')&61+5(-1+ & A)+>@/)<( 5!+ (! 2/>&(,!+ ,&'0 5!(9(10 @1+,&'";$!0

,&' A";!2,."$&' )&' ,&'0 *+@&B1(1$. Y! )"/)1+ (! 2'µµ&"*=(&(,!+ µ1 ,+0 ')&61$B1+0

,&' A)+>@/)&(,&0 5!+ (! 12,+?%&'( ,.( )"&2)?41+? ,&'0 2,.( 1)+,'#$! ,&' A"1'(.,+5&-

)"&;"?µµ!,&0 )&' ,&'0 !(!,$41,!+ .

D,& ,/@&0 ,.0 VA &+ *&+,.,/0 4! )"/)1+ (! )!"&'2+?2&'( ,! !)&,1@/2µ!,! ,.0

VA 21 1+6+59 2-;;"!µµ! )&' 1(61+5,+5? 4! !)&,1@1$,!+ !)9 ,! !59@&'4! µ/". : I,("6362,

G<,;8 ;", JB#%?%,, @0%)5<B(µ ")", K1D2)-(- , !,9<,%6>"+&" 5!+ 9 ,,+ ?@@& 5"$(1,!+ !)!"!$,.,& !)9 ,&( A)+>@/)&(,!. E& µ/;14&0 ,&' 2';;"?µµ!,&0 1B!",?,!+ 5!,?



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

2

)1"$),<2. !)9 ,& 4/µ!. I1(+5? 61( 1(4!""-(1,!+ . 2';;"!*3 &;5<6=( VA 21 >?"&0 ,.0

)&+9,.,!0 3 ,.0 )1+"!µ!,+530/1";!2,."+!530 1";!2$!0.

D,& ,/@&0 ,&' 2';;"?µµ!,&0 & *&+,.,30 ')&#"1&-,!+ (! 5!,!4/21+ 6-& !(?,')!

,.0 VA 2,. I"!µµ!,1$! (/(! ;+! ,& !"#1$& ,.0 I"!µµ!,1$!0 5!+ /(! ;+! ,. P+>@+&435. ,&' Eµ3 µ!,&0) 5!+ /(! !(?,')& 21 5?41 A)+>@/)&(,!. M A)+>@/)<( 5!,!4/,1+ ,. >!47&@&;$!

,.0 GA #".2+7&)&+=(,!0 ,& 2#1,+59 /(,')& >1>!$<2.0 (>1>!$<2. >!47&@&;$!0). : GA

>!47&@&;1$,!+ 71 ?"+2,! ,& 6/5! (10) 5!+ >?2. ,& )/(,1 (5).

M L!(&(+2790 G+)@<7!,+5=( A";!2+=( )1"+/#1+ !(!@',+5/0 )@."&*&"$10 ;+! ,.

6+!6+5!2$! 15)9(.2.0 6+)@<7!,+530 1";!2$!0 (http://www.mbg.duth.gr/files/File/Kan_dipl.pdf).

7.2 I0,)>%02 K1/)%/,($%= I;0*/-(-4 H,0<3$"),;./ I>6"(,./

C!))? O;@!Z! , A)$5&'"&0 L!4.;3,"+! , [email protected]

S)&'5&'>?@! D<,."$! , A)$5&'"&0 L!4.;3,"+! , sboukouv@ mbg.duth.gr

I@'590 K+59@!&0 , A)$5&'"&0 L!4.;.,30 , [email protected]

S1,!@@+(&- ["'2&-@! A.E.A.C , cmetalli@ mbg.duth.gr

G-& 15)"92<)&+ ,&' *&+,.,+5&- 2'@@9;&' (61( /#&'( &"+241$)

N)1-4'(. D'(,&(+27&-: S1,!@@+(&- ["'2&-@! , cmetalli@ mbg.duth.gr, 25510-

30641



!"#$"%&&% '!#()*+ ,&-&%,#' &#".%/-' 0.#1#$.%' & $2+2,./-'

%/%)-&%3/# 2,#' 2013-2014

14 2567894 :2*".% 2"$%',-".% ;"#+,.',-".% ).)%/,./2'

*"2' ).)%/,./2' MON%)2'

&#+%)2' ECTS

).)%'/#+,2'

!"#$%& '$( )$*+*'$%,- ./$#0&12- 3 1 0 4 4 5 34562#7 -8(+9*:97

;24$%& & 34<='(47 >712?( 3 3 0 6 4 6 407

.$#('@'& #07 )$*+*'?( 3 3 0 6 4 6 >(0A5%7

)$*#0(0$#0$%& 2 0 1 3 3 4 34562#7 -B=$C$547-

.$#('@'& #074 D/*+*'$#0$%& )$*+*'?(

3 3 0 6 4 6 ;+"%<-

3''+$%5 E 2 0 0 2 2 3 34562#7 -F(+1/5407

'(+#1# 2<%&-+#( 16 10 1 27 21 30

24 2567894 :2*".% 2"$%',-".% ;"#+,.',-".% ).)%/,./2'

*"2' ).)%/,./2' MON%)2'

&#+%)2' ECTS

).)%'/#+,2'

3''+$%5 EE 2 0 2 2 2 3 34562#7 -F(+1/5407

.$#('@'& #07 )$*+*'?( G='(4$#1H4 3 3 0 6 4 7 >(0A5%7

G='(4$%& >712?( 3 3 0 6 4 7 !"+(%0(%?9*"

!"#$%*I712?( %($ #0*$I2?(

)$*J"#$%&- 3 2 0 5 4 6 407

;2420$%& E 3 3 0 6 4 7 K(=*"+5%*"-L5#I*"

'(+#1# 2<%&-+#( 14 11 2 25 18 30



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

22

3! "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

!"#$%&'() * 3 3 0 6 4 6 +),-#&)-.-/)01.2%

+#-")34 +"3-#5"#6#7() 3 3 0 6 4 6 /#,-3#,0.8- 96($6")

/,00)-"34 !"#6#7() 4 3 0 7 5 7 /:;;)

<"1)7=74 10%2 >'$2#6#7()

+#-")348 !"#6#7()8 3 0 0 3 3 4 ?3.5@%8

+#-")34 !"#6#7() * 4 0 1 5 5 7 ?)2@)60A:B#,6#8

.73282 "9,60327 17 9 1 27 21 30

4 ! "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

!"#$%&'() ** 4 3 0 7 5 7 +),-#&)-.-/)01.2%

C,1"#6#7() 4 3 0 7 5 7 D)BB.

E'2'0"34 ** 3 3 0 6 4 7 +)-#,6.3#,-C)348

+#-")34 !"#6#7() ** 3 0 0 3 3 4 E)6.2%8

E#2"@")34 <3;-)1% 3)" /,00)-"34 ?%&)0#@:0%1% 4 0 0 4 4 5 ?)2@)60A:B#,6#8 -E)6.2%8

.73282 "9,60327 18 9 0 27 21 30



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

23

5! "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

+FG#@#" 10% +#-")34 !"#6#7() 0 6 3 9 3 6?3.5@%8/E-%7#-(#,/E)6.2%8/

?)2@)60A:B#,6#8

+#-")34 H2#1#5"#6#7() 4 3 0 7 5 7 96($6")

E'2'0"34 D6%G,1&I2 3)" <JF6"J% 3 3 0 6 4 6 D.1$#,

!"#B6%-#;#-"34 4 3 0 7 5 7 E6,3:8

<&5-,#6#7() 3)" +#-")34 !"#6#7()

H2.B0,J%8 3 0 0 3 3 4 E-%7#-(#,-?3.5@%8

.73282 "9,60327 14 12 3 29 20 30

6o "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

<;)-&#1&F2% !"#0'$2#6#7() 3 2 0 5 4 4 /#,-3#,0.8

<"1)7=74 10% K#&4 5"#&#-(=2 3 3 0 6 4 5 H7")2".2

D)"@)7=7"34 1 0 0 1 1 2 /'@-.3)

<B)77'6&)0"34 H2.B0,J% 0=2

!"#'B"10%&:2=2 1 0 0 1 1 2 /'@-.3)

E#2"@"=&)0"34 3 0 3 6 4 5 +)-#,6.3#,-+B#,3#,5.6)

LMG&"1% /,00)-"348 N'"0#,-7()8 3 0 1 4 3 4 E)6.2%8-?)2@)60A:B#,6#8

+)G4&)0) <B"6#748 (4) 8 0 0 8 8 8

.73282 "9,60327 22 5 4 31 25 30



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

24

7! "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

E'2'0"34 H2G-IB#, 4 3 0 7 5 5 C)348

H2.B0,J% <;)-&#7I2 0=2 !"#'B"10%&I2 10%2 O7'()

3 0 3 6 4 5 +B#,3#,5.6)

+#-")34 P',-#5"#6#7() 3 0 0 3 3 4 E-%7#-(#,

D-=0'o&"34 3 0 1 4 4 4H7")2".2-/)01.2% -+),-#&)-.

>'$2#6#7() +#-")348 !"#6#7()8 3 0 0 3 3 4 ?3.5@%8-E-%7#-(#,

+)G4&)0) <B"6#748 (4) 8 0 0 8 8 8

.73282 "9,60327 24 3 4 31 27 30

8! "#$%&'! (")*+, "*-,./0*+, 1*23/+./0*+, 4+4,5/+5".

)*". 4+4,5/+5". MON,4".

623,4". ECTS

4+4,.523/".

K"B6=&)0"34 '-7)1() 12 12 12 36 20 30

.73282 "9,60327 12 12 12 36 20 30

.73282 :*2-*,66,/2. 85 24 12 155 119 240



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

25

6,(06,/, ":+82-0.

!"#$%"&" '()*+,$- '".)/+0 '1"%$/+2 (6 +2 )

3%45" 6 :!+.)"7$ 8)+*+,9" & :;/;&)7$

*10#6#7() 2 0 0 2 2 2 H2.G'1% -N)&B-#B#M6#,

<"@"3. GF&)0) OB#6#7"10"348 !"#6#7()8

2 0 0 2 2 2 407

<"@"3. QF&)0) !"#B6%-#;#-"348 2 0 0 2 2 2 E6,3:8

?M7$-#2'8 >'$2"3F8 3)" <;)-&#7F8

10%2 !"#6#7() /,00.-#, 1 0 1 2 2 2 /:;;)

B"#6#7() !6)10#3,00.-=2 3)" H2)7F22%1%8

2 0 0 2 2 2 E-%7#-(#,

!"#6#7() 0%8 ?,&B'-";#-.8 2 0 0 2 2 2 ?3.5@%8

!"#%G"34 2 0 0 2 2 2 407

D-)30"34 R13%1% * 2 0 0 2 2 2 *

E'2'0"34 10% K"3)"#1M2% 3)" 10%2

*)0-#@"3)10"34 2 0 0 2 2 2 C)348

A-$F8 <B"$'"-%&)0"3:0%0)8 10"8

!"#'B"104&'8**2 0 0 2 2 2 ** (8#, 'J)&42#,)

<"@"3. GF&)0) H2#1#5"#6#7()8 2 0 0 2 2 2 96($6")

*?,20#2(10-") : /)01.2% H"3)0'-(2% **?,20#2(10-") : +B#,3#,5.6) ?.

3%45" 8 : <")5",=,)7>/ – ?)5"7&)7$-

K"@)30"34 D-)30"34 R13%1% * (+"3-#@"@)13)6() )

1 0 1 2 2 2 /'@-.3)

K"@)30"34 +'G#6#7() 1 0 1 2 2 2 /'@-.3)

?,&5#,6',0"34 3)" <3B)"@',0"34 S,$#6#7()

1 0 1 2 2 2 /'@-.3)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

26

!"#$%"&" '()*+,$- @;)%;.)/+0 '1"%$/+2 (7 +2 )

3%45" 6 3%45" 6 :!+.)"7$ 8)+*+,9" & :;/;&)7$

+#-")34 T"3#6#7() 2 0 0 2 2 2 9)0A.3%

*#6#7() 2 0 0 2 2 2 +),-#&)-.- 96($6")

L)@"#5"#6#7() 2 0 0 2 2 2 H2.G'1% -U%1"&:B#,6#8

C)-&)3#6#7() 2 0 0 2 2 2 D)BB.

9%&"3F8 '2I1'"8 3)G%&'-"248

A=48 1 0 1 2 2 2 C,6)30)3(@#,

E'2'0"34 <B(30%0=2 H1G'2'"I2 3)" +'0);-)10"34 *)0-"34

2 0 0 2 2 2 +)-#,6.3#,

+#-")34 !"#6#7() C,0I2 2 0 0 2 2 2 407

+%$)2"1&#( #73#7F2'1%8 2 0 0 2 2 2 E)6.2%8-D.1$#,-D)BB.

+#-")34 !"#0'$2#6#7() 3)" K")0-#;4

2 0 0 2 2 2 /#,-3#,0.8-E)6.2%8

H-$F8 @")$'(-"1%8 AI=2

'-7)10%-(#, 2 0 0 2 2 2 H2.G'1% -OV%6.20%8

?0#"$'() C)-&)3',0"348 9%&'()8

3)" 9%&'()8 C,1"3I2 D-#W:20=2 2 0 0 2 2 2 C,6)30)3(@#,

3%45" 8 : <")5",=,)7>/ – ?)5"7&)7$- K"@)30"34 D-)30"34 R13%1% ** (?$#6"34 <;)-&#74 )

1 0 1 2 2 2 /'@-.3)

<3B)(@',1% <2%6(3=2 1 0 1 2 2 2 /'@-.3)

T-7)2=1")34 S,$#6#7() 1 0 1 2 2 2 /'@-.3)



!"#$%$#&'() *&$#+,"&) -(./ 01.21+33$#.) 45./*67

! O! 518#."#"9) "#!$%$&' $#( )*. +$#(' 2013-2014 ,) )*#-#(,./#(0 $# 0&# 12342)55) 67#(890.

! :! 2"#"9) "#!$%$&' $#( )*. +$#(' 2013-2014 ,) )*#-#(,./#(0 $# 0&# 12342)55) 67#(890 5; ;<)=2;/% $# 5>,%5) ?!#@%5;=) A $# #7#=#

&@#(0 .8% 8!8)@$;= /$# )*)8%5)B*3 &$#' 2012-2013.

! :! 3"#"9) "#!$%$&' $#( )*. +$#(' 2013-2014 ,) )*#-#(,./#(0 *)$> $# 5;4)-C$;2# 5&2#' $#( (7#-#=7#( $D0 67#(890 $#(' , $# 7)-!3

12342)55) 67#(890. 12#*;!5&0#( 35D' 0) $#(' 8#,;= % 8(0)$3$%$) )0 $# ;7!,(5#C0 0) )7#*$./#(0 $# 8=7-D5) 8!8)*$!*.' ;7>2*;!)'

@D2=' 0) ;7%2;)/$;= # /(0#-!*3' )2!,53' 8!8)*$!*90 D290 $#( 7$(@=#( $#(' , ,) !/@C/;! 4!) )($#C' $# 0&# 72342)55) /7#(890 D'

72#' $) 7)2)*>$D: ()) E) 7)2)*#-#(,./#(0 $) 5),.5)$) 1)!8)4D4!*. *)! F7)44;-5)$!*. G0>7$(<% ?!#;7!/$%530D0 (H) E) $#(' 8#,;= $#

8!*)=D5) 0) 7)2)*#-#(,./#(0 $) 6 7)!8)4D4!*> 5),.5)$) ;7!-#4.' (4) E) 8!8)@,#C0 $# 5>,%5) I#2!)*. J;(2#H!#-#4=) /$# 7# ;<>5%0#

$# &$#(' 2014-2015 5; H>/% $# 0&# 72342)55).! :! 4 "#"9) "#!$%$&' $#( )*. +$#(' 2013-2014 ,) )*#-#(,./#(0 $# 7)-!3 12342)55) 67#(890. E) $#(' 8#,;= $# 8!*)=D5) 0)

7)2)*#-#(,./#(0 /$# 8# ;<>5%0# $# 5>,%5) F!8!*> ,&5)$) K7#-#4!/$!*.' ?!#-#4=)' (D' &0) ;* $D0 4 5),%5>$D0 $#( ;<)5.0#(

72#*;!5&0#( 0) )7#*$./#(0 $# 7!/$#7#!%$!*3 409/%' @2./%' L/K.

! :$ 3$;<3$#$ ?!#@%5;=) A *)! F!/)4D4. /$% M#5. H!#5#2=D0 8; ,) 8!8)@$#C0 $# )*)8%5)B*3 &$#' 2013-2014.

! :$ 3$;<3$#$:

• M#5. *)! N;!$#(24=) ?!#5#2=D0

• I#2!)*. G0#/#H!#-#4=) A *)! AA

• F5H2(#-#4=) *)! I#2!)*. ?!#-#4=) G0>7$(<%' (4+3).

• O#0!8!)*. +*"2)/% *)! 6%5)$#83$%/% AA

• I#2!)*. *)! P($$)2!*. ?!#-#4=)

E) 8!8)@$#C0 5; $%0 ("!/$>5;0% 8#5. 4!) $;-;($)=) "#2> /$#(' 3;$;=' "#!$%$&' $#( 2013-2014.

! :$

3$;<3$#$:

• 1)!8)4D4!*. • F7)44;-5)$!*. G0>7$(<% ?!#;7!/$%530D0 • M!8)*$!*. 12)*$!*. Q/*%/% A

E) 8!8)@$#C0 4!) 729$% "#2> /$#(' 3;$;=' "#!$%$&' $#( )*. ;$. 2013-2014.

! :$ 3$;<3$#$ "5&=.2<):

• 6(5H#(-;($!*. *)! F*7)!8;($!*. R(@#-#4=)

• M!8)*$!*. I;,#8#-#4=)



E) 8!8)@$#C0 4!) 729$% "#2> /$#(' 3;$;=' "#!$%$&' $#( )*. ;$. 2013-2014.

! :$ 3$;<3$#$:

• I&,#8#! /$% I#2!)*. ?!#-#4=)

• I#2!)*. G0#/#H!#-#4=) .

• F5H2(#-#4=) *)! I#2!)*. ?!#-#4=) G0>7$(<%' (3+0).

• SC,5!/% P($$)2!*.' N;!$#(24=)'.

E) 8!8)@$#C0 4!) 729$% "#2> /$#(' 3;$;=' "#!$%$&' $#( )*. ;$. 2014-2015.

! :. 3+;>3$ T;@0#-#4=) I#2!)*.' ?!#-#4=)' ,) 8!8)@$;= /$# 5# ;<>5%0# /$#(' 3;$;=' "#!$%$&' $#( 2013-2014 *)! ;7#5&0D' 8; ,)

8!8)@$;= /$#(' 4;$;=' "#!$%$&' $#( 2014-2015. E) 8!8)@$;= *)0#0!*> /$#(' 4;$;=' "#!$%$&' $#( 2015-2016.

! :. 3+;>3$ 12D$;#5!*. : ,) 8!8)@$;= 4!) 729$% "#2> /$#(' 4;$;=' "#!$%$&' $#( 2015-2016.

! :. 3+;>3$ I#2!)*. J;(2#H!#-#4=) (3+2) ,) 8!8)@$;= 4!) $;-;($)=) "#2> /$#(' 4;$;=' "#!$%$&' $o 2013-2014.

! :. 3+;>3$ I#2!)*. J;(2#H!#-#4=) (3+0) E) 8!8)@$;= 4!) 729$% "#2> /$#(' 4;$;=' "#!$%$&' $#( 2014-2015.

! :. 3+;>3$ "5&=.2<): F!8!*> E&5)$) G0#/#H!#-#4=)' ,) 8!8)@$;= 4!) 729$% "#2> /$#(' 3;$;=' "#!$%$&' $#( 2014-2015.

! :$ 3$;<3$#$ "5&=.2<) :

• M!8)*$!*. 12)*$!*. Q/*%/% AA

• F*7)=8;(/% F0%-=*D0

• :24)0D/!)*. R(@#-#4=)

E) 8!8)@$#C0 4!) 729$% "#2> /$#(' 4;$;=' "#!$%$&' $#( 2014-2015.

! :. 3+;>3$ "5&=.2<): F!8!*> ,&5)$) K7#-#4!/$!*.' ?!#-#4=)' ,) 8!8)@$;= /$#(' 3;$;=' "#!$%$&' $#( 2013-2014.

! :. 3+;>3$ "5&=.2<): 12D$;U0!*. T;@0#-#4=) ,) 8!8)@$;= /$#(' 4;$;=' "#!$%$&' $D0 2013-2014 *)! 2014-2015.

! :. 3+;>3$ "5&=.2<): M!8)*$!*. $D0 ?!#;7!/$%590 ,) 8!8)@$;= 4!) $;-;($)=) "#2> /$#(' 4;$;=' "#!$%$&' $#( 2013-2014.

! :. 3+;>3$ "5&=.2<): V)25)*#-#4=) ,) 8!8)@$;= 4!) 729$% "#2> /$#(' 4;$;=' "#!$%$&' $#( 2014-2015. M;0 ,) 8!8)@$;= $# 2013-2014.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

!"#$"%&'"(&

)!&%#"*+$,*(

'-./'-+*(



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

29

0)1$,/ 2$- 3$&4&2$,"1 "!$1+/'"1

"56789: )/" ;<=> .=?<@A> ;<=> -BCDB8> EFGACHFCI> 7:96G= ECTS

A’ ! 3 1 4 6

-9HFC=F7=9FC:@ BHJK:F H:L 7AMD7AH:>

1) "# $%&'( )(# &*+,-.(/0 /#( -'1('/.(/0 '(&#2320 /#( #+#&/4-5&5 2(# .(6 2'+(/76

/#( 8')'9(%$'(6 7++,('6 :*&(/06 , #-#1#;.5.'6 2(# .5+ /#.#+45&5 .3+ :#(+,)7+3+

/#( )5<#+(&)%+ -,* ')-97/,+.#( &.5 =5)';# , .5 >(,<5)';# /#( .5 ?,1(#/0 >(,9,2;#

/#( @'+'.(/0 .

2) "# -'1(21AB'( .(6 :*&(/76 #1<76 &.(6 ,-,;'6 C#&;D,+.#( .# .'<+,9,2(/A '12#9';#

-,* <15&(),-,(,E+.#( 2(# .5 )'97.5 .56 E956 /#( .5+ #9959'-;$1#&5 )' #*.0 &.5

?,1(#/0 >(,9,2;# /#( .5 @'+'.(/0 .

3) "# -#1,*&(A&'( )(# '(&#232(/0 #+#:,1A &' :(9,&,:(/A 87)#.# -,* #22;D,*+ .5

:*&(/0 /#( .5 D30 (:#(+4)'+# #*.,,12A+3&56 , -,9*-9,/4.5.# , 8'1),$*+#)(/0 .56

'F79(F56 , /.#.)

4) "# $5)(,*120&'( 7+#*&)# 2(# -'1(&&4.'15 #+#D0.5&5 /#( )'97.5 &.(6 ':#1),276

.56 G*&(/06 &.5 ?,1(#/0 >(,9,2;# /#( @'+'.(/0 .

5) "# $';F'( .5+ '-(&.5),+(/0 )78,$, /#( +# '(&A2'( &' 7++,('6 /#( ,1876 -1#/.(/76

$(#<';1(&56 '-(&.5),+(/06 2+%&56.

!=<F=KJ7=9: H:L 7AMD7AH:>

H, )A85)# #-,.'9'; )(# #+#&/4-5&5 .56 C#&(/06 8'31;#6 .56 G*&(/06 )' 7):#&5 &.(6

#1<76 .56 &E2<1,+56 :*&(/06 /#( .(6 ':#1),276 .,*6 2(# .5+ )'97.5 .56 7)C(#6 E956. I

C#&(/0 8'31;# &*)-951%+'.#( )' .5+ -#1,*&;#&5 '-()71,*6 /#(+,.4)3+ ':#1),2%+ /#(

.'<+(/%+ -,* 7<,*+ A)'&5 ':#1),20 &.(6 >(,9,2(/76 J-(&.0)'6 , )' 7):#&5 &' .'<+(/76

$(#2+3&.(/06 #-'(/4+(&56 , )(/1,&/,-;#6 /#( :#&)#.,&/,-;#6. H# )A85)# -'1(9#)CA+'(

'C$,)#$(#;# 3 %1'6 8'31;#6 /#( 1 %1# :1,+.(&.51;,*/'12#&.51;,* 4-,* '/-,+,E+.#(

'-()71,*6 '12#&;'6 #-4 .,*6 :,(.5.76 &' '($(/A 87)#.# :*&(/06 )' ':#1),20 &.(6

C(,9,2(/76 '-(&.0)'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

30

.=?<8HFCJ 7I<:>

• "FBAN?ND: 0LBFCD CAF ':<FACD 3F:O:N@A CAF 2=9=HFCD. I G*&(/0 &.5 )'97.5 .56 7)C(#6

E956. J-(&.5),+(/0 )78,$,6. G*&(/A )'2785 , -'(1A)#.# , )'.10&'(6 /#( &:A9)#.#.

K(#<';1(&5 '-(&.5),+(/06 2+%&56 , #+#D0.5&5 , /1(.(/0 /#( )'97.5 '-(&.5),+(/06

C(C9(,21#:;#6 , ,12A+3&5 /#( -#1,*&;#&5 '-(&.5),+(/06 2+%&'(6.

• "5IOF58 $G=P9 BH8 0LBFCD $ : >#&(/76 7++,('6 /9#&(/06 )5<#+(/06. L;+5&5 &' )(#

$(A&.#&5 . M')'9(%$'(6 +4),( /;+5&56. !-'1+4),( $(#.015&56 '+712'(#6 , ,1)06 /#(

&.1,:,1)06. KE+#)5 C#1E.5.#6. N+# -#1A$'(2)# #-4 .5+ /9#&(/0 )5<#+(/0 : .,

)#/1,)41(, 36 *$1,$*+#)(/4 &3)A.(,. !$1,$*+#)(/76 )78,$,( #+A9*&56 /#( :*&(/76

#1<76 .56 :*2,/7+.1(&56.

• "5IOF58 $G=P9 BH8 0LBFCD $$: I9'/.1,)#2+5.(&)46: G,1.;, /#( 59'/.1(/0 $E+#)5 .

L(+,E)'+, :,1.;, /#( )#2+5.(/0 $E+#)5 . N++,(# .,* -'$;,*. I9'/.1,)#2+5.(/A /E)#.#

/#( 8'31;# .,* Maxwell. GA&)# 59'/.1,)#2+5.(/%+ /*)A.3+ , #9959'-;$1#&5 I? )' .5+

7)C(# E95 , ':#1),276 I? &.(6 C(,9,2(/76 '-(&.0)'6.

• "5IOF58 $G=P9 BH8 0LBFCD $$$: OE2<1,+5 G*&(/0 : P32)76 &.5+ /9#&(/0 8'31;#

(#/.(+,C,9;# )79#+,6 &%)#.,6 , :3.,59'/.1(/4 :#(+4)'+, , :A&)# #-,114:5&56

*$1,24+,* , &.#8'14.5.# #.4)3+). !-48'&5 Planck-Einstein. !-48'&5 Bohr.L*)#.,&3)#.($(#/46 $*Q&)46. R1<76-#F(%)#.# /C#+.,)5<#+(/06. L*)#.,&*+A1.5&5

&3)#.($;3+. R1<0 #-1,&$(,1(&.;#6. H, A.,), &.5+ /C#+.,)5<#+(/0 . O-(+ /#(

#-#2,1'*.(/0 #1<0 .,* Pauli. LC#+.(/0 M'31;# .56 S956: H#*.4&5)# &3)#.;$(# /#(

2'+(/'*)7+5 #1<0 .,* Pauli. R1<0 #-1,&$(,1(&.;#6 /#( #7+#5 /;+5&5 .,* )(/14/,&),*.

• +: 0?> BH8 1QNK<:98 0LBFCD. GE&5 , <#1#/.51(&.(/A , $(A$,&5 . ?'97.5 .,* :A&)#.,6

.,* :3.46. H, :36 36 /C#+.(/4 &3)#.;$(,. T#1#2320 :3.46. H, :36 36 2'3)'.1(/0

#/.;+# , #+A/9#&5 , $(A89#&5 , ,-.(/A &*&.0)#.# , :*&(/0 41#&56 , )(/1,&/4-(,. H, :36 36 /E)# , -493&5 , /1*&.#99,21#:;#. !9(/A /E)#.#: $(#2+3&.(/0 #-'(/4+(&5 /#(

)(/1,&/,-;# )' *-715<,*6.

• / QO8 BH8 1QNK<:98 0LBFCD. -H:7FCD CAF ':<FACD ,O@7ACA. To A.,), /#( ., )41(, &.5

/C#+.,)5<#+(/0 . R.,)(/76 /#( ),1(#/76 '+'12'(#/76 /#.#&.A&'(6. ?5<#+(&),;

#9959'-;$1#&56 :3.,+;3+ /#( E956. R.,)(/0 /#( ),1(#/0 :#&)#.,&/,-;#. G3.#E2'(# ,

C(,:3.#E2'(#. G*&(/76 #1<76 LASER /#( ':#1),276 .,*6 &.(6 C(,9,2(/76 '-(&.0)'6

('-7)C#&5 , #-'(/4+(&5 , )(/1,&/,-;# , ,-.(/0 -#2;$'*&5 ). G*&(/76 #1<76 #/.;+3+ = /#(



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

31

':#1),276 .,*6 &.(6 C(,9,2(/76 '-(&.0)'6 (#-'(/4+(&5 )' #/.;+'6 = , *-,9,2(&.(/0

.,),21#:;#).

• / QO8 BH8 1QNK<:98 0LBFCD. !L<D9A>. T%6 ';+#( :.(#2)7+,6 , -*10+#6? H( &*2/1#.';

.,+ -*10+# '+(#;,? J+'12'(#/46 (&,9,2(&)46 &.,+ -*10+#. ‘J-(.1'-4)'+,(’ -*10+'6 /#( ,( ($(4.5.76 .,*6. P#$('+712'(# (# $(A&-#&5 , C $(A&-#&5 , 2 $(A&-#&5 ). R+(<+'*.76

#/.(+,C,9(%+. K,&()'.1;# /#( '-(-.%&'(6 .56 1#$('+712'(#6 &.5+ 7)C(# E95 .

P#$(,Q<+587.'6 , #-'(/4+(&5 /#( )(/1,&/,-;# )' <10&5 1#$(,Q&,.4-3+

(&-(+851,21A:5)# , SPECT, PET). G#&)#.,&/,-;# , #-'(/4+(&5 /#( )(/1,&/,-;# -*15+(/,E

)#2+5.(/,E &*+.,+(&),E.

• 'AC<:BC:RFC6 1LBHD7AHA. ?#/1,&/,-(/A :*&(/A &*&.0)#.#. ?#/1,&/,-(/A :*&(/A

)'2785 . N++,(# .56 8'1),/1#&;#6. "4),( .56 8'1),$*+#)(/06. J+.1,-;# /#( D30 .T,9E-9,/# &*&.0)#.#. M'1),$*+#)(/0 ,12A+3&5 E956.

"<NABH8<FACI> -BCDB=F>

U( '12#&.51(#/76 #&/0&'(6 -'1(9#)CA+,*+ '/-4+5&5 /#( -#1,*&;#&5 #.,)(/06 '12#&;#6

&' '($(/A 87)#.# :*&(/06 )' ':#1),20 &.5 ),1(#/0 C(,9,2;# /#( 2'+'.(/0 . U( '12#&;'6

#-#(.,E+ #+#D0.5&5 /#( )'97.5 -,99#-9%+ '-(&.5),+(/%+ C(C9(,21#:(/%+ -52%+ ,

209'-.5 -#1,*&;#&5 .,* 87)#.,6 /#( '-(-97,+ &*D0.5&5 )7&# #-4 '13.0&'(6. U(

:,(.5.76/.1('6 )-,1,E+ +# '-(97F,*+ 87)# '12#&;#6 #-4 /#.A9,2, -A+3 #-4 70 '($(/%+ 8')A.3+.

EFG6BC:9H=>

". ,AOG:QG8 , R+#-951%.1(# L#8520.1(# G*&(/06 V#.1(/06 R-'(/4+(&56 - H59'Q#.1(/06.

!<:H=F9J7=9A 1LNN<677AHA

+@HO:>:

I G*&(/0

O0)'1#

.H4),6

V &

VV 1LNN<ASIA>: U(/,+4),* J."."CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 L10.56 TJR:> & %<J9:> TCG:B8>: I1A/9'(, L10.56 2004ISBN: 960-7309-08-1,?GFCJ> ")E&U&1: 274



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

32

+@HO:>: L':A9#(# G*&(/06 1LNN<ASIA>: R+#2+3&.4-,*9,6 R., K4+5 J.,

L#1#/%&.#6 M., L,)+5+,E G."CG:HFCJ> &@C:>: J/$4&'(6 W0.5 T'9#2;# & O(# UJ +JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 1998ISBN: 960-431-249-9

,?GFCJ> ")E&U&1: 11065

187=FPB=F> 'AMD7AH:>

I )'97.5 '-()71,*6 8')#.(/%+ '+,.0.3+ .,* )#80)#.,6 *-,&.51;D'.#( )' &5)'(%&'(6

-,* $(#+7),+.#( #-4 .,+ (&.,<%1, .,* )#80)#.,6

+@HO:>: JF79(F5 .3+ V$'%+ &.5 G*&(/0

1LNN<ASIA>: J. L#9$,E$5

+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: G*&(/76 R1<76 L#8;D5&56 & G*2,/7+.1(&56


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: H, G36


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: P#$('+712'(#: R+;<+'*&5 , >(,9,2(/76 J-(-.%&'(6 & =10&5 2(# ?'97.5 .56 N)C(#6 S956


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: T*15+(/46 ?#2+5.(/46 O*+.,+(&)46: G#&)#.,&/,-;# & R-'(/4+(&5


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: R/.;+'6 =


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011

+@HO:>: !-715<,(


+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

33

0LOO6GF: "<NABH8<FACP9 -BCDB=?9

@(# .(6 '12#&;'6 -,* '/-,+,E+.#( &.# -9#;&(# .3+ '12#&.51;3+ -1,.';+'.#( '-()71,*6

C(C9(,21#:;# 2(# /A8' 87 )# -,* -'1(9#)CA+'( /*1;36 A181# &' $('8+0 '-(&.5),+(/A

-'1(,$(/A.

EFGACHFCI> – 'AM8BFACI> 'IM:G:F

K(#97F'(6 &.# C#&(/A 8'315.(/A 87)#.# -,* #+#9E,+.#( -#1#-A+3. J-()71,*6

'F'($(/'*)7+# 87)#.# #+#9E,+.#( &' '12#&;'6 :,(.5.%+ (#.,)(/76 0 )(/176 ,)A$'6) /#(

-#1,*&(AD,+.#( #-4 .,*6 :,(.5.76 , '+% #/,9,*8'; $('F,$(/0 &*D0.5&5 . L#.A -'1;-.3&5 ,

2;+,+.#( $(#97F'(6 #-4 -1,&/'/95)7+,*6 '-(&.0),+'6 , /#( &*+'12#.(/76 #&/0&'(6 0 //#(

#&/0&'(6 #*.,#F(,9425&56 )7&3 $(#$(/.E,*. H, $($#/.(/4 *9(/4 .,* )#80)#.,6 $(#.;8'.#( &., $(#$;/.*, , 4-,* /#( *-,&.51;D'.#( &*D0.5&5 (forum) .3+ &*))'.'<4+.3+.

2OPBBA EFGABCAO@A>

J995+(/A. L#.A -'1;-.3&5 , 5 &*+(&.%)'+5 '-(-97,+ C(C9(,21#:;# '-()71,*6 '+,.0.3+

)-,1'; +# ';+#( /#( &.# #229(/A

'IM:G:F A5F:OJN8B8>- 3AM7:OJN8B8

@1#-.76 'F'.A&'(6 )' '13.0&'(6 -,99#-9%+ '-(9,2%+. T#1,*&;#&5 '12#&;#6 /#(

#F(,9425&5 #*.06 )' CA&5 &*2/'/1()7+# , /#8,1(&)7+# /1(.01(# , -,* #+#/,(+%+,+.#( &.,*6

:,(.5.76 &.5+ #1<0 .,* )#80)#.,6 /#8%6 /#( &.,+ (&.,<%1, .,* )#80)#.,6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

34

2"($,/ ,-$ -(&#2-(/ %/'"$-

"56789: )/" ;<=> .=?<@A> ;<=> -BCDB8> EFGACHFCI> 7:96G=> ECTS

A’ ) 3 3 4 6


I ),1(#/0 C(,9,2;# ';+#( &.5 CA&5 .56 =5)';# /#8%6 ,( C(,9,2(/76 $('12#&;'6 )'9'.%+.#(

&' ),1(#/4 '-;-'$,. I /#.'F,<0+ ),1(#/0 '-(&.0)5 ';+#( 5 =5)';# . N.&( &., )A85)# #*.4

-,* $($A&/'.#( &., -1%., 'FA)5+, ,( :,(.5.76 /#9,E+.#( +# ')-'$%&,*+ C#&(/76 #1<76

/#( 8'31;'6 2(# .5 $,)0 .3+ #.4)3+ , .# .1,<(#/A , .,*6 <5)(/,E6 $'&),E6 , .# 59'/.1,+(/A

:#(+4)'+# , .,+ -'1(,$(/4 -;+#/# /#( .(6 -'1(,$(/76 ($(4.5.'6 .3+ &.,(<';3+. J-(-97,+

-17-'( +# 2;+,*+ 2+%&.'6 .3+ $*+A)'3+ -,* '+'12,E+ &' ),1(#/4 /#( *-'1),1(#/4

'-;-'$, , 4-36 , $'&)46 *$1,24+,* /#( ,( $*+A)'(6 Van der Waals. R*.A #-,.'9,E+ .,

*-4C#81, 2(# .5+ /#.#+45&5 .56 &.'1',<5)';#6 -,* ,$52'; &.5 <5)';# .3+ &*)-94/3+ ,

#-#1#;.5., '12#9';, 2(# .5+ /#.#+45&5 .3+ C(,9,2(/%+ $('12#&(%+ , 4-36 '+D*)(/76

#+.($1A&'(6 /9-. O., '-;-'$, .3+ <5)(/%+ $('12#&(%+ &' $(#9E)#.# #+#-.E&&,+.#( ,(

C#&(/76 #1<76 .56 &*)-'1(:,1A6 .3+ ,*&(%+ &' $(#9E)#.# , ,( #1<76 .56 <5)(/06

(&,11,-;#6 , .56 <5)(/06 /(+5.(/06 /#( ,( 7++,('6 .3+ ,F73+ , CA&'3+ /#( .3+ #9A.3+. I

8'31;# .56 &*)-'1(:,1A6 .3+ <5)(/%+ ,*&(%+ &' $(#9E)#.# ')-'$%+,+.#( )'

'12#&.51(#/76 #&/0&'(6 -,* #:,1,E+ # ) -#1#&/'*76 $(#9*)A.3+ $(#:413+

&*2/'+.1%&'3+ , C) .(.9,$4.5&5 $(#9*)A.3+ , 2) pH, $ ) 1*8)(&.(/A $(#9E)#.#. H79,6 ,(

:,(.5.76 'F#&/,E+.#( /#( &.(6 ,-.(/76

($(4.5.'6 .3+ $(#9*)A.3+ )' .5+ :#&)#.,:3.,)'.1;# *-'1(%$,*6-,1#.,E. X9# .#

-#1#-A+3 8'31,E+.#( #-#1#;.5.'6 2+%&'(6 2(# +# /#.#+,58'; 5 8'31;# /#( ,(

'12#&.51(#/76 #&/0&'(6 )#85)A.3+ -,* 7-,+.#( &' -'1(&&4.'1# C(,9,2(/A 87)#.#.


.=?<8HFCJ 7I<:> K,)0 .3+ #.4)3+ , #.,)(/A , ),1(#/A /#( *C1($(&)7+# .1,<(#/A , <5)(/46 $'&)46 , -'1(,$(/46

-;+#/#6 /#( -'1(,$(/76 ($(4.5.'6 .3+ &.,(<';3+. U),(,-,9(/46 , '.'1,-,9(/46 /#( )'.#99(/46

$'&)46 , 59'/.1,+(/A :#(+4)'+# , $'&)46 *$1,24+,* , /#( $*+A)'(6 Van der Waals. O.'1',<5)';# ,

#1<76 <5)';#6 &*)-94/3+ , ,+,)#.,9,2;# #+412#+3+ '+%&'3+. K(#9E)#.# , #1<76 <5)(/06

(&,11,-;#6 , <5)(/0 /(+5.(/0 , ,F7# , CA&'(6 /#( A9#.#. O5)#+.(/A &.,(<';# , '+%&'(6 .,*6 /#(

C(,9,2(/76 .,*6 ($(4.5.'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

35


H, )A85)# -'1(9#)CA+'( 331'6 '12#&.51(#/76 #&/0&'(6 &' 87)#.# -,* #:,1,E+

$(#9E)#.# /#( ,-.(/76 ($(4.5.'6 $(#9*)A.3+:

1. JVOR@Y@I OHU JP@ROHIPVU , TRPROLJ!JO KVRZ!?RHY" 2. GRO?RHUGYHU?JHPVR

3. HVHZUKUHIOI KVRZ!?RHY"

4. pH KVRZ!?RHY"

5. P!M?VOHVLR KVRZ!?RHR

EFG6BC:9H=>

Z7/.,1#6 407/80


H;.9,6: >#&(/76 #1<76 #+412#+56 <5)';#6 O*221#:7#6 : @'%12(,6 T+'*)#.(/A/56 /#.J/$,.(/46 U;/,6: O.#),E95 R.J H4-,6 & =14+,6 N/$,&56: 2006ISBN: 9789603516644L3$(/46 >(C9;,* &.,+ JE$,F,: 22656

H;.9,6: @'+(/0 /#( #+412#+5 =5)';# O*221#:7#6 : @. J. ?#+,*&A/5 .

J/$,.(/46 U;/,6: L*1(#/;$5 R:,; H4-,6 & =14+,6 N/$,&56: 1994 (2006)ISBN: 960-343-272-5L3$(/46 >(C9;,* &.,+ JE$,F,: 6030


e-class


«R&:A9'(# , M'31;# /#( T1#/.(/0 J12#&.51(#/%+ R&/0&'3+ @'+(/06 =5)';#6»,

G*9#/.#/;$,* L3+&.#+.;+# (J/$4&'(6 KTM).


• $(#97F'(6

• '12#&;'6 2(# ., &-;.(

• -1,.'(+4)'+5 C(C9(,21#:;#

• e-class



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

36

2OPBBA EFGABCAO@A>

E995+(/A


O*+'/.;)5&5 #-4 C#8),9,2;# &' -1,21#))#.(&)7+'6 'F'.A&'(6 'F#)0+,* , &*))'.,<0 &.,

'12#&.01(, , '12#&;'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

37

"$1-2*2/ 1+/ 3$&4&2$-


A’ ) 3 3 4 6

A9HFC=F7=9FC:@ BHJK:F H:L 7AMD7AH:>

U( &.4<,( .,* )#80)#.,6 ';+#(:

#) 5 '(&#2320 .,* -13.,'.,E6 :,(.5.0 &.(6 C#&(/76 C(,9,2(/76 7++,('6 /#( &.5+

-,9*-9,/4.5.# .56 $,)06 /#( 9'(.,*12;#6 .3+ ),+,/E..#13+ /#( -,9*/E..#13+

,12#+(&)%+ &' '-;-'$, ),1(#/4 /#( /*..#1(/4 ,

C) 5 2+31();# .,* )' .5 D3(/0 /#( :*.(/0 -,(/(94.5.# ,

2) 5 )'97.5 .56 $,)06 /#( 9'(.,*12;#6 .3+ :*.(/%+ ,12#+(&)%+ ,

$) 5 '(&#2320 .3+ #1<%+ .56 'F79(F56 /#( :*9,27+'&56 .3+ ,12#+(&)%+ ,

&.) 5 'F,(/';3&5 )' ., C#&(/4 '12#&.51(#/4 'F,-9(&)4 /#( .,*6 -'(1#)#.(/,E6

<'(1(&),E6 .,* C(,942,* '1'*+5.0 ,

D) 5 'FA&/5&5 &.5 2102,15 /#( /1(.(/0 &/7B5 /#( 5 &E+$'&5 .56 -#+'-(&.5)(#/06 )'

-1,52,E)'+'6 2+%&'(6 .,* &., '*1E.'1, -'$;, .56 C(,9,2;#6


.=?<8HFCJ 7I<:>

• U( ($(4.5.'6 /#( 5 -1,79'*&5 .56 D306.

• H# C(,)41(# /#( .# <#1#/.51(&.(/A .,*6.

• K,)0 /#( 9'(.,*12;# -1,/#1*3.(/%+ /*..A13+

• K,)0 /#( 9'(.,*12;# '*/#1*3.(/%+ /*..A13+ • U12#+(&),; <31;6 /*..#1(/0 $,)0 ((,;-(,'($0 -prions)

• R1<76 .#F(+4)5&56 /#( 'F79(F56 .3+ ,12#+(&)%+

• T1%.(&.# /#( )E/5.'6

• G*.(/0 -,(/(94.5.#

• K,)0 /#( 9'(.,*12;# #+%.'13+ :*.(/%+ ,12#+(&)%+

• W3(/0 -,(/(94.5.#


1. ?(/1,&/,-;# (3 %1'6),

2. T1,/#1*3.(/A /E..#1# (3 %1'6),



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

38

3. J*/#1*3.(/A /E..#1# - .'<+(/76 <1%&56 (3 %1'6),

4. H#F(+4)5&5 #&-,+$E93+ (6 %1'6),

EFG6BC:9H=>

'. -O=5@:L %AHV6C8 , J-;/. L#8520.1(# @'+. >(,9,2;#6.


+@HO:>: >VUZU@VR 1LNN<ASIA>: R. W0&5 , W. ?#),E156 , L . ?,E.,* "CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 M'& #6 +JR:> & %<J9:> TCG:B8>: ZA1(&# 2008ISBN: 978-960-8029-66-8

,?GFCJ> ")E&U&1: 6006 +@HO:>: >VUZU@VR HU?UO V 1LNN<ASIA>: N. A. Campbell & Reece"CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 '/$4&'(6 L10.56 +JR:> & %<J9:> TCG:B8>: I1A/9'(, , 2010ISBN: 978-960-524-306-7,?GFCJ> ")E&U&1: 5445

+@HO:>: W3,9,2;#. U9,/9513)7+'6 #1<76. H4),6 V 1LNN<ASIA>: C.P. Hickman, L.S. Roberts, A. Larson"CG:HFCJ> &@C:>: [3+ +JR:> & %<J9:> TCG:B8>: 2002


+@HO:>: J(&#2320 &.5 >(,9,2;#-J12#&.51(#/76 #&/0&'(6

1LNN<ASIA>: ?. R9'F;,*- =#.DA/5 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 2008


K(#97F'(6 , '12#&.01(# , -1,C,976 &<'.(/%+ )' .5+ E95 +.,/*)#+.71.


@1#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

39

3$&1+-+$1+$,/


A’ ) 2 1 3 4


H, )A85)# .56 >(,&.#.(&.(/06 &.,<'E'( :

•

&.5+

'(&#2320

&.(6

)'84$,*6

71'*+#6

-,*

<15&(),-,(,E+.#(

&.(6

C(,9,2(/76

'-(&.0)'6 &0)'1# ,

• &.5+ -#1,*&;#&5 .3+ &5)#+.(/4.'13+ &.#.(&.(/%+ .'<+(/%+ 2(# .5+ -'1(21#:0 /#(

.5+ #+A9*&5 '1'*+5.(/%+ $'$,)7+3+ /#(

• &.5+ 'F,(/';3&5 .3+ :,(.5.%+ )' &.#.(&.(/A -#/7.#.


1K=GFAB7J> 7=MJG:L I<=L9A>

U 149,6 .56 O.#.(&.(/06 &.5+ '-(&.5),+(/0 71'*+# , $(#.E-3&5 '1'*+5.(/06 *-48'&56-

&.#.(&.(/A ),+.79# , C#&(/76 )78,$,( 71'*+#6 (-'(1#)#.(/76--#1#.015&56 , -'1(21#:(/76-

#+#9*.(/76 , &*2<1,+(/76--1,,-.(/76-#+#$1,)(/76), /9(+(/76 $,/()76 , .*<#(,-,;5&5 ,

/#8,1(&)46 -958*&),E 71'*+#6 , .*<#;, $';2)# , )78,$,( $'(2)#.,95B;#6 , /#8,1(&)46

)'278,*6 $';2)#.,6 , &< '.(/46 /;+$*+,6 (RR), 942,6 &<'.(/%+ -(8#+,.0.3+ (OR), &*2<*.(/,;

-#1A2,+.'6 , &:A9)#.# , 79'2<,6 #F(,-(&.;#6 /#( '-#+#95B()4.5.#6 )'.10&'3+.

!=<FN<ASFCD BHAHFBHFCD

?'.#C95.0 , ';$5 )'.#C95.%+ , &.#.(&.(/,; -;+#/'6 , 21#:(/76 )78,$,( , #1(8)5.(/A

-'1(21#:(/A )7.1# /'+.1(/06 .A&56 /#( )'.#C95.4.5.#6 , &*+.'9'&.06 )'.#C95.4.5.#6 ,/#.#+,)0 Gauss, )'.#&<5)#.(&),; , :*&(,9,2(/76 .()76 , #F(,9425&5 '12#&.51(#/%+

'*15)A.3+ ('*#(&85&;# , '($(/4.5.# , 8'.(/0 /#( #1+5.(/0 -1,2+3&.(/0 #F;#), /#)-E95 ROC

(Receiver Operator Curve).

"CH@78B8 RA<A7IH<?9

H14-,( '/.;)5&56 -#1#)7.13+ , $(#&.0)#.# ')-(&.,&E+56 , .*-(/4 &:A9)# , '/.;)5&5 (i) .56

)7&56 .()06 /#( '+46 -,&,&.4 &' 7+#+ -958*&)4 /#( (ii) .56 $(#:,1A6 .3+ )7&3+ .()%+ /#(

.3+ -,&,&.%+ &' $E, -958*&),E6.

TO=NK:> LR:MIB=?9 I 7++,(# .,* &.#.(&.(/,E '972<,* , )5$'+(/0 /#( '+#99#/.(/0 *-48'&5 , &:A9)#.# .E-,* V



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

40

/#( VV , (&<E6 '+46 '972<,* , .()0 p '+46 '972<,* , 5 7++,(# .56 &.#.(&.(/06 &5)#+.(/4.5.#6 ,

79'2<,6 *-,87&'3+ (i) 2(# .5 )7&5 .()0 /#( ., -,&,&.4 &' 7+# -958*&)4 /#( (ii) 2(# .5

$(#:,1A .3+ )7&3+ .()%+ /#( .3+ -,&,&.%+ &' $E, -958*&),E6 , -#1#.510&'(6 /#.A

D'E25 .

-96OLB8 GFABR:<6> R+A9*&5 $(#&-,1A6 2(# #+'FA1.5.# $';2)#.# , -;+#/#6 #+A9*&56 $(#&-,1A6 , -,99#-976

&*2/1;&'(6.

-96OLB8 R:F:HFCP9 G=G:7I9?9

T;+#/'6 &*+A:'(#6 , $,/()#&;# <2 36 /1(.01(, &*&<7.(&56 /#( /#906 -1,&#1),206 -,(,.(/%+

<#1#/.51(&.(/%+.

1HAHFBHFCD BLBKIHFB8 CAF =56<H8B8

O*+.'9'&.06 &*&<7.(&56 r .,* Pearson, )78,$,6 '9#<;&.3+ .'.1#2%+3+ , -14C9'B5 , #-94

),+.79, 21#))(/06 -#9(+$14)5&56.'8 RA<A7=H<FC:@ IO=NK:F

T9',+'/.0)#.# /#( )'(,+'/.0)#.# .3+ )5 -#1#)'.1(/%+ '972<3+ , 79'2<,6 Kolmogorov-

Smirnov 2(# 7+# $';2)# , 79'2<,( Wilcoxon signed rank, Mann-Whitney U, Kruskal-Wallis,

&*+.'9'&.06 &*&<7.(&56 1 .,* Spearman.

EFG6BC?9

2<8NJ<F:> +<LWF698> , R+#-9513.06 L#8525.06 V#.1(/06 O.#.(&.(/06

!<:H=F9J7=9A BLNN<677AHA

+@HO:>: R1<76 >(,&.#.(&.(/06 1LNN<ASIA>: ?. Pagano, K. Gauvreau (?'.A:1#&5 –

J-()79'(#: U*1#+;# K#:+0 )"CG:HFCJ> &@C:>: JZZI"

%<:9:O:N@A ICG:B8>: 2002+JR:> ICG:B8>: R80+# ,?GFCJ> ")E&U&1: 16295

+@HO:>: >(,&.#.(&.(/0 1LNN<ASIA>: K. H1(<4-,*9,6 , R. HD%+,* , L .

L#.&,*2(A++5 "CG:HFCJ> &@C:>: T#1(&(A+,* R.J. %<:9:O:N@A ICG:B8>: 2002+JR:> ICG:B8>: R80+# ,?GFCJ> ")E&U&1: 41236



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

41

+@HO:>: J(&#2320 &.5 L9(+(/0 >(,<5)';# /#( .5+ J12#&.51(#/0 O.#.(&.(/0

1LNN<ASIA>: R. L,1.&A156 , V. H7+.'6 , @. H1*B(A+56 , ".T#-A+#6 , L . R+#2+3&.4-,*9,6

"CG:HFCJ> &@C:>: R$'9:%+ L*1(#/;$5 R.J.

%<:9:O:N@A ICG:B8>: 2010+JR:> ICG:B8>: M'&&#9,+;/5 ,?GFCJ> ")E&U&1: 5928


@1#-.0 'F7.#&5 &., .79,6 .,* 'F#)0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

42

"$1-2*2/ 1+/( )!&4&2$1+$,/ 3$&4&2$-


A’ ) 3 3 4 6


#) J(&#2320 &.5+ -951,:,1(/0 .

C) H, 9'(.,*12(/4 &E&.5)# Unix.

2) I 29%&&# -1,21#))#.(&),E C.

!=<F=KJ7=9: H:L 7AMD7AH:> .=?<8HFCJ 7I<:>

UNIX: V&.,1;# , =#1#/.51(&.(/A , J/$4&'(6 , $(#$(/#&;'6 login-logout, ., &E&.5 µ# #1<';3+ .,* unix,

/#.A9,2,( /#( *-,/#.A9,2,( , $,µ0 #1<';3+ , <10&.'6 /#( ,µA$'6 <15&.%+ , -1,&.#&;'6

#1<';3+ /#( /#.#9423+ , '+.,976 cd, ls, chmod, <#1#/.01'6 *-,/#.A&.#&56 , /#8('13µ7+5

';&,$,6-7F,$,6 , -1,21Aµµ#.#-:;9.1# , '-#+#-1,&$(,1(&µ46 '(&4$,*-'F4$,* , &E+$'&5

-1,21#µµA.3+ (pipes), '+.,976 find, cat, tail, tee, ln, mv, cp, rm, umask, chown, chgrp, mkdir, rmdir, gzip,

gunzip, tar, more, A99'6 '+.,976 : who, finger, date, cal, K;/.*# : #1<(.'/.,+(/0 $(/.E3+ , TCP/IP, DNS,

-13.4/,99# '-(/,(+3+;#6 /#( -1,21Aµµ#.# : ssh, ftp, telnet, talk, unix mail, (#+)#&:A9'(# $(/.E3+ ,http /#( µ(# '(&#2320&.5+ html. I 29%&&# -1,21#µµ#.(&µ,E C : µ'.#C95.76 , $59%&'(6 , 5

'+.,90 for /#( 7+8'.'6 for, 5 &*+A1.5&5 printf(), ,( '+.,976 if /#( ., D'E2,6 '+.,9%+ if-else,

9,2(/,; .'9'&.76 , 5 '+.,90 while, 5 &*+A1.5&5 scanf(), -#1#$';2µ#.# ':#1µ,206 (1),

<#1#/.01'6 encodings /#( 21#µµ#.,&';1'6 , $093&5 /#( <10&5 µ'.#C95.%+ .E-,* <#1#/.51%+

/#( -(+A/3+ .,*6 , ';&,$,6-7F,$,6 <#1#/.013+ , ':#1µ,276.


ROLIOI 15 , YPJO 3

• K(#$(/#&;'6 login, logout.

• JF,(/';3&5 µ' ., &E&.5 µ# #1<';3+ .,* 9'(.,*12(/,E &*&.0 µ#.,6 UNIX. J+.,976 cd, pwd,

ls, mkdir, rmdir.

• JF,(/';3&5 µ' 7+#+ #-4 .,*6 #/49,*8,*6 /'(µ'+,21A:,*6 (editors) : vi, joe, nedit, xedit .

• =10&5 .,* /'(µ'+,21A:,* 2(# .5 $5 µ(,*12;# $*, #1<';3+ /'(µ7+,*main.c /#( function.c (.#

,-,;# -'1(7<,*+ .,+ -52#;, /%$(/# '+46µ(/1,E -1,21Aµµ#.,6 &' 29%&&#

-1,21#µµ#.(&µ,E C).

• JF,(/';3&5 µ' .(6 '+.,976 cat, more, cp, mv, rm.

ROLIOI 25 , YPJO 3



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

43

• T'1#(.713 'F,(/';3&5 µ' .(6 '+.,976 cd, pwd, ls, mkdir, rmdir, cp, mv, rm, cat, more.

• O5 µ#&;# /#( <10&5 .,* &*µC49,* ~

• O5 µ#&;# /#( <10&5 .3+ <#1#/.013+ *-,/#.A&.#&56 * /#( ?

• L#(+,E12(# '+.,90 : chmod.

• =10&5 .,* /'(µ'+,21A:,* 2(# .5+ .1,-,-,;5&5 '+46 '/ .3+ #1<';3+-,* ';<#.'

$5 µ(,*120&'( &.5+ 15 A&/5&5 .

ROLIOI 35 , YPJO 3

• T'1#(.713 'F,(/';3&5 µ' .5 <10&5 .,* unix shell /#( '-#+A95B5 .56 E956 .3+

-1,52,Eµ'+3+ '12#&.51;3+.

• I '+.,90 tar /#( 5 <10&5 .56.

• L#(+,E12('6 '+.,976 : grep, find, tail, head, wc.

• L#(+,E12('6 '+.,976 : w, who, finger. =10&5 .,* /'(µ'+,21A:,* 2(# .5+ $5 µ(,*12;# .3+

#1<';3+ .plan /#( .project -,* <15&(µ,-,(,E+.#( #-4 .5+ '+.,90 finger .

ROLIOI 45 , YPJO 3

• H'9(/0 '-#+A95B5 /#( A&/5&5 4956 .56 E956 .,* UNIX

ROLIOI 55 , YPJO 3

• @'+(/0 $,µ0 -1,21#µµA.3+ C.

• ?'.#29%..(&5 -1,21#µµA.3+ C.

• I &*+A1.5&5 printf().

• I '+.,90 for.

• I '+.,90 if /#( ., D'E2,6 '+.,9%+ if-else.

• HE-,( µ'.#C95.%+ : #/71#(,( (int), /(+5.06 *-,$(#&.,906 (float), µ,+,$(A&.#.,( -;+#/'6.

ROLIOI 65 , YPJO 3

• J:#1µ,276: ., -1421#µµ# -,* *9,-,('; .5+ µ78,$, .3+ '9#<;&.3+ .'.1#2%+3+.

ROLIOI 75 , YPJO 3

• R+A9*&5 .,* -1,21Aµµ#.,6 *-,9,2(&µ,E µ,1(#/%+ C#1%+ -13.'Q+%+.

• H1,-,-,;5&5 .,* -1,21Aµµ#.,6 *-,9,2(&µ,E µ,1(#/%+ C#1%+ %&.' +# *-,9,2;D'.#( .,

A81,(&µ# .3+ $'(/.%+ *$1,:,C(/4.5.#6 .3+ #µ(+,F73+ µ(#6 -13.'\+56.• H1,-,-,;5&5 .,* -1,52,Eµ'+,* -1,21Aµµ#.,6 %&.' +# -#1,*&(AD'( .,*6 $';/.'6

*$1,:,C(/4.5.#6 #+A #µ(+,FE (/#( #+A 21#µµ0 'F4$,*).

• T'1#(.713 .1,-,-,;5&5 .,* -1,21Aµµ#.,6 *$1,:,C(/4.5.#6 %&.'+# -#1,*&(AD'( &.5+

7F,$, µ(# 21#:(/0 #-'(/4+(&5 .56 /#.#+,µ06 *$1,:,C(/4.5.#6 2(# ,94/9515 .5+

-13.'\+5 .

• =10&5 .,* .'9'*.#;,* #*.,E -1,21Aµµ#.,6 2(# .,+ -1,&$(,1(&µ4.,* #1(8µ,E /#( .56

87&'36 *$14:,C3+ .µ5 µA.3+ ($(#µ'µC1#+(/%+ #-'9;/3+) &.5 >#/.51(,1,$,B;+5 .

ROLIOI 85 , YPJO 3• O*221#:0 , µ'.#29%..(&5 /#( '/.79'&5 $E, µ(/1%+ -1,21#µµA.3+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

44

EFG6BC:9H=>

(FCJOA:> '. 2OLCJ> , J-;/,*1,6 L#8525.06 (!-,9,2(&.(/0 /#( K,)(/0 >(,9,2;#).


+@HO:>: T901'6 '2<'(1;$(, .56 C1LNN<ASIA>: Aitken, Jones+JR:> & %<J9:> TCG:B8>: 65 7/$./2006ISBN: 978-960-512-491-5,?GFCJ> ")E&U&1: 12373

+@HO:>: U UKI@UO HU! Linux

1LNN<ASIA>: WELSH, DALHEIMER & KAUFMAN+JR:> & %<J9:> TCG:B8>: 35 /2002ISBN: 960-209-408-7,?GFCJ> ")E&U&1: 13813

+@HO:>: H, -'1(CA99,+ -1,21#))#.(&),E UNIX1LNN<ASIA>: BRIAN W. KERNIGHAN, ROB PIKE+JR:> & %<J9:> TCG:B8>: 25 /2011ISBN: 978-960-332-208-5,?GFCJ> ")E&U&1: 12530814


KVRZJ]JVO , JP@ROHIPVRLJO ROLIOJVO


JP@ROHIPVRLJO ROLIOJVO 30%, J]JHROJVO (multiple choice) 70%



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

45

-224$,- $

"56789: )/" ;<=> .=?<@A> ;<=> -BCDB8> EFGACHFCI> 7:96G=> ECTS-' ) 2 0 2 2


! I 'F,(/';3&5 .3+ :,(.5.%+ )' '($(/A /';)'+# '-(&.5),+(/06 ,1,9,2;#6 -,* A-.,+.#( .,*

#+.(/'()7+,* .,*6 , %&.' +# #+#-.EF,*+ ., 9'F(942(4 .,*6 , )' &/,-4 +# C,5858,E+ &.5

)'97.5 .56 F7+56 C(C9(,21#:;#6 /#( +# -1,'.,()#&.,E+ 2(# .5 )'99,+.(/0 71'*+# &' 7+#+

.,)7# 4-,* ,( -'1(&&4.'1'6 -5276 C1;&/,+.#( &.# R229(/A ! I 'FA&/5&5 .3+ :,(.5.%+ &.5+ /#.#+45&5 /#( #-4$,&5 21#-.,E /#( -1,:,1(/,E 942,* /#( 5

-#1A99595 A&/5&0 .,*6 &.# 21#))#.(/A /#( &*+.#/.(/A :#(+4)'+# .56 #229(/06 29%&&#6 ,

%&.' +# /#.#+,0&,*+ .5 $,)0 /#( .(6 9'(.,*12;'6 .56 29%&&#6.

! O.4<,6 .,* )#80)#.,6 ';+#( '-;&56 +# '+(&<E&'( .5+ /1(.(/0 &/7B5 /#( +# -1,/#97&'(

&*D5.0&'(6 &.5+ R229(/0 29%&&# -A+3 &' D5.0)#.# .56 2'+'.(/06 -,* ';+#(

#):(&C5.0&()#.


O., R^ 'FA)5+, .# /';)'+# -,* )'9'.%+.#( '(&A2,*+ .,*6 :,(.5.76 &.5+ '-(&.5),+(/0

,1,9,2;# $(#:413+ &*+#:%+ /9A$3+: V#.1(/0 (Iuman Anatomy, Common Diseases and Ailments),

R+813-,9,2;# (Hheories of Evolution), =5)';# (Chemical Elements and Compounds) /.9.-

EFG6BC:9H=>

(AO7R69H8 "OI98 , JJKVT

EFGACHFCI> CAF 7AM8BFACI> 7IM:G:F

U( :,(.5.76 #&/,E+.#(:

! &.5 9'F(9,2(/0 /#( +,5)#.(/0 '-'F'12#&;# #*8'+.(/%+ /'()7+3+ , 4-36 '-(&.5),+(/A

A181# #-4 -'1(,$(/A /#( ':5)'1;$'6

! &.5 &E+8'&5 21#-.,E /'()7+,* (-#1A21#:,( , -'1(90B'(6 , '-(&.,976 /.9.-)

! &' #&/0&'(6 21#))#.(/06 , &E+.#F56 , :3+5.(/06

! &.5+ /#.#+45&5 /#( #-4$,&5 -1,:,1(/,E 942,* )' <10&5 CD /#( DVD

U( :,(.5.76 '12AD,+.#( #.,)(/A 0 /#.A ,)A$'6 #+A9,2# )' .5 $1#&.51(4.5.# .

'IM:G:F A5F:OJN8B8>/XAM7:OJN8B8>



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

46

@1#-.0 'F7.#&5 &., .79,6 /A8' 'F#)0+,*.

2OPBBA GFGABCAO@A>

J995+(/A


@1#-.0 'F7.#&5 &., .79,6 /A8' 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

47

-224$,- $


3' ) 2 0 2 2


• I 'F,(/';3&5 .3+ :,(.5.%+ )' '($(/A /';)'+# '-(&.5),+(/06 ,1,9,2;#6 -,* A-.,+.#( .,*

#+.(/'()7+,* .,*6 , %&.' +# #+#-.EF,*+ ., 9'F(942(4 .,*6 , )' &/,-4 +# C,5858,E+ &.5

)'97.5 .56 F7+56 C(C9(,21#:;#6 /#( +# -1,'.,()#&.,E+ 2(# .5 )'99,+.(/0 71'*+# &' 7+#+

.,)7# 4-,* ,( -'1(&&4.'1'6 -5276 C1;&/,+.#( &.# R229(/A

• I 'FA&/5&5 .3+ :,(.5.%+ &.5+ /#.#+45&5 /#( #-4$,&5 21#-.,E /#( -1,:,1(/,E 942,* /#( 5

-#1A99595 A&/5&0 .,*6 &.# 21#))#.(/A /#( &*+.#/.(/A :#(+4)'+# .56 #229(/06 29%&&#6 ,%&.' +# /#.#+,0&,*+ .5 $,)0 /#( .(6 9'(.,*12;'6 .56 29%&&#6.

• O.4<,6 .,* )#80)#.,6 ';+#( '-;&56 +# '+(&<E&'( .5+ /1(.(/0 &/7B5 /#( +# -1,/#97&'(

&*D5.0&'(6 &.5+ R229(/0 29%&&# -A+3 &' D5.0)#.# .56 2'+'.(/06 -,* ';+#(

#):(&C5.0&()#.


O., >^ 'FA)5+, '-(972,+.#( '($(/A /';)'+# >(,9,2;#6 (The Cell, The Biological Clock) ?,1(#/06 >(,9,2;#6 /#( @'+'.(/06 ( Alterations in the Genetic Material, DNA Repair, The Genetic Content of the

Human Genome), %&.' ,( :,(.5.76 +# 'F,(/'(38,E+ )' .(6 C#&(/76 7++,('6 /#( .,*6 '($(/,E6

41,*6 -,* <15&(),-,(,E+.#( &.5+ '-(&.0)5 .,*6.

EFG6BC:9H=>

"#9)-A+.5 J., JJKVT

EFGACHFCI> CAF 7AM8BFACI> 7IM:G:F U( :,(.5.76 #&/,E+.#(:

• &.5 9'F(9,2(/0 /#( +,5)#.(/0 '-'F'12#&;# #*8'+.(/%+ /'()7+3+ , 4-36 '-(&.5),+(/A

A181# #-4 -'1(,$(/A /#( ':5)'1;$'6

• &.5 &E+8'&5 21#-.,E /'()7+,* (-#1A21#:,( , -'1(90B'(6 , '-(&.,976 /.9.-)

• &' #&/0&'(6 21#))#.(/06 , &E+.#F56 , :3+5.(/06

• &.5+ /#.#+45&5 /#( #-4$,&5 -1,:,1(/,E 942,* )' <10&5 CD /#( DVD

U( :,(.5.76 '12AD,+.#( #.,)(/A 0 /#.A ,)A$'6 #+A9,2# )' .5 $1#&.51(4.5.#



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

48

'IM:G:F A5F:OJN8B8>/XAM7:OJN8B8>

@1#-.0 'F7.#&5 &., .79,6 /A8' 'F#)0+,*.

2OPBBA GFGABCAO@A>

J995+(/A


@1#-.0 'F7.#&5 &., .79,6 /A8' 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

49

"$1-2*2/ 1+/ 3$&4&2$- &#2-($1'*(


3’ ) 3 3 4 6


#) '(&#2320 &.5+ ,12#+(&)(/0 C(,9,2;# , )' 7):#&5 &.5+ -,(/(94.5.# .3+ &*&.5)A.3+

/#( .56 9'(.,*12;#6 .,*6 &.,*6 $(A:,1,*6 D3(/,E6 ,12#+(&),E6 )7&# #-4 .5 &*2/1(.(/0

)'97.5 493+ .56 :*&(,9,2;#6 .,*6 , #-4 .,*6 ),+,/E..#1,*6 )7<1( .,+ A+813-,

C) '(&#2320 &.5+ ,(/,9,2;# /#( .5 $(#.015&5 .,* -'1(CA99,+.,6

2) 2+31();# )' ,12#+(&),E6 - ),+.79#

$) 2+31();# )' ., :*&(/4 -'1(CA99,+ .56 -'1(,<06


M'315.(/4 )71,6

M'315.(/4 )71,6

• V&.,; D3(/%+ ,12#+(&)%+

• U),(4&.#&5 – M'1),1E8)(&5 • "'*1(/4 OE&.5)# /#( #(&85.01(# 412#+#

• L#9*-.01(, – O.51(/.(/4 – ?*Q/4 &E&.5)#

• L*/9,:,1(/4 – R+#-+'*&.(/4 &E&.5)#

• T'-.(/4 – R-'//1(.(/4 &E&.5)#

• R+#-#1#232(/4 &E&.5)# - R+A-.*F5

• U(/,9,2;# ,(/,&*&.5)A.3+ – RC(,.(/,; -#1A2,+.'6 – ?'2#$(#-9A&'(6

• P,0 J+712'(#6 - H1,:(/76 &<7&'(6 - >(,2'3<5)(/,; /E/9,(

• U(/,9,2;# -958*&)%+

• U(/,9,2;# C(,/,(+,.0.3+

J12#&.51(#/76 R&/0&'(6

1. R+#.,);# $1,&4:(9#6 (3 %1'6)

2. R+#.,);# C#.1A<,* (3 %1'6)

3. R+#.,);# -,+.(/,E (3 %1'6)

4. T1,'.,()#&;# , -1#2)#.,-,;5&5 /#( #+A9*&5 $'$,)7+3+ '12#&;#6 -'$;,* (9 %1'6)

EFG6BC:9H=>

'. -O=5@:L %AHV6C8 , J-(/. L#8520.1(# @'+. >(,9,2;#6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

50


+@HO:>: >VUZU@VR 1LNN<ASIA>: R. W0&5 , W. ?#),E156 , L . ?,E.,* "CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 M'& #6 +JR:> & %<J9:> TCG:B8>: ZA1(&# 2008ISBN: 978-960-8029-66-8

,?GFCJ> ")E&U&1: 6006

+@HO:>: >VUZU@VR HU?UO VV 1LNN<ASIA>: N. A. Campbell & Reece"CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 '/$4&'(6 L10.56 +JR:> & %<J9:> TCG:B8>: I1A/9'(, , 2010ISBN: 978-960-524-306-6,?GFCJ> ")E&U&1: 7619

+@HO:>: W3,9,2;#. U9,/9513)7+'6 #1<76. H4),6 VV 1LNN<ASIA>: C.P. Hickman, L.S. Roberts, A. Larson"CG:HFCJ> &@C:>: [3+ +JR:> & %<J9:> TCG:B8>: 2002


T@HO:>: J(&#2320 &.5 >(,9,2;# U12#+(&)%+-J12#&.51(#/76 #&/0&'(6

1LNN<ASIA>: ?. R9'F;,*- =#.DA/5 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 2008


K(#97F'(6 , '12#&.01(# , '/-#($'*.(/0 '/$1,)0 , -1,C,976 &<'.(/%+ )' .5+ E95

+.,/*)#+.71.


@1#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

51

&#2-($,/ %/'"$-


3' ) 3 3 4 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) I 2+%&5 .56 $,)06 , .56 &.'1',<5)';#6 , .3+ 59'/.1,+(/%+ :#(+,)7+3+ /#( .3+

:#&)#.,&/,-(/%+ $'$,)7+3+ .3+ ,12#+(/%+ '+%&'3+ /#8%6 ,( C(,9,2(/,E '+$(#:71,+.,6

'+%&'(6 ';+#( &<'$4+ #-,/9'(&.(/A ,12#+(/06 :E&56.C) I 2+%&5 &' ),1(#/4 '-;-'$, .3+ $,)(/%+ /#( 59'/.1,+(/%+ <#1#/.51(&.(/%+ .3+

'.'1,/*/9(/%+ ,12#+(/%+ '+%&'3+ , .3+ #)(+,F73+ /#( .3+ &#/<A13+ -,* #-,.'9,E+ .#

/E1(# &*&.#.(/A .3+ C(,9,2(/,E '+$(#:71,+.,6 ),1;3+.


.=?<8HFCJ 7I<:>

• U+,)#.,9,2;#

• V&,)71'(#

• I9'/.1,+(/A :#(+4)'+#

• O.'1',<5)';#

• G#&)#.,&/,-;#

• ?5<#+(&),; U12#+(/%+ R+.($1A&'3+

• R13)#.(/4.5.#

• R13)#.(/76 /#( J.'1,/*/9(/76 J+%&'(6

• Z(-;$(#

• R)(+,F7#

• OA/<#1#


1. R+#/1*&.A993&5 (3 %1'6).

2. J/<E9(&5 (3 %1'6)

3. R-4&.#F5 (3 %1'6)

4. =13)#.,21#:(/76 )78,$,( (9'-.06 &.,(CA$#6 , &.0956 , (,+#+.#99#206), (3 %1'6)

5. R+(<+'E&'(6 $,)(/%+ <#1#/.51(&.(/%+ ,)A$3+ ($(-9%+ $'&)%+ , /#1C,+*9;3+ , &#/<A13+ ,#)(+,F73+), (3 %1'6).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

52

EFG6BC:9H=>

,. %. 0LOACHAC@G:L , R+#-951%.1(# L#8520.1(# =5)';#6 U12#+(/%+ J+%&'3+.


+@HO:>: U12#+(/0 =5)';# J-;.,),: ?71,6 T1%., /#( K'E.'1,

1LNN<ASIA>: "(/,9#\$56 K5)0.1(,6 "CG:HFCJ> &@C:>: W0.5 T'9#2;# & O(# U.J.+JR:> & %<J9:> TCG:B8>: 15 7/$,&5 1996ISBN: 978-960-456-291-6,?GFCJ> ")E&U&1: 13004940

+@HO:>: J-;.,)5 U12#+(/0 =5)';# 1LNN<ASIA>: >A1C,2956 R+#&.A&(,6 @."CG:HFCJ> &@C:>: W0.5 T'9#2;# & O(# U.J.

+JR:> & %<J9:> TCG:B8>: 15 7/$,&5 2005ISBN: 960-431-948-5,?GFCJ> ")E&U&1: 10998


+@HO:>: R&:A9'(# , M'31;# /#( T1#/.(/0 J12#&.51(#/%+ R&/0&'3+ @'+(/06 =5)';#6

1LNN<ASIA>: L . =. G*9#/.#/;$,* +JR:> & %<J9:> TCG:B8>: !-51'&;# K5),&('*)A.3+ K.T.M., 2007


=15&(),-,(,E+.#( 59'/.1,+(/76 -#1,*&(A&'(6 &.(6 $(#97F'(6 .3+ )#85)A.3+ -,* ';+#(

$(#87&()'6 &.,*6 :,(.5.76 )7&3 .,* -1,21A))#.,6 e-class, ),1(#/A ),+.79# 2(#

.1(&$(A&.#.5 #-'(/4+(&5 /#( /#9E.'15 /#.#+45&5 .,* <%1,* , &')(+A1(# /#(

'12#&.51(#/76 #&/0&'(6.

2OPBBA EFGABCAO@A>

J995+(/0


@1#-.76 JF'.A&'(6 , G*99A$(# J12#&.51(#/%+ R&/0&'3+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

53

0)1$,&%/'"$- ,-$ 1+&$%"$- 3$&0)1$,/1


3' ) 3 2 5 4


U( &.4<,( .,* )#80)#.,6 ';+#(:

H, )A85)# #-,&/,-'; &.5+ 'F,(/';3&5 .3+ :,(.5.%+ )' .,*6 :*&(/,E6 +4),*6 -,* $(7-,*+

.# C(,9,2(/A &*&.0)#.# /#( .,*6 '(&A2'( &.(6 #1<76 : $(#.510&'(6 /#( )'.#.1,-06 '+712'(#6

/#( )AD#6 , #+#+.(&.1'-.4.5.#6 /#( #*841)5.3+ $('12#&(%+.


.=?<8HFCJ 'I<:>

R) J(&#232(/A )#85)#.(/A /#( C#&(/76 :*&(/76 7++,('6.

>) L#.#&.#.(/76 'F(&%&'(6 -,* -'1(21A:,*+ .(6 8'1),:*&(/76 ($(4.5.'6 #'1;3+ /#( *21%+.

@) U -1%.,6 8'1),$*+#)(/46 +4),6 ':#1),D4)'+,6 &' $('12#&;'6 )'.#.1,-06 '+712'(#6.

K) U $'E.'1,6 8'1),$*+#)(/46 +4),6 8'1),$*+#)(/06 : R+#+.(&.1'-.4.5.# $('12#&(%+

J) R99#276 /#.A&.#&56

OH) !$#.(/A $(#9E)#.#

W) GA&'(6 .56 E956

I) L*)#.(/0 /#( 59'/.1,)#2+5.(/4 :A&)#

M) R9959'-($1A&'(6 :3.46/E956

V) H'<+(/76 $(#<31(&),E – =13)#.,21#:;'6– G#&)#.,)'.1;# )AD#6 – :8,1(&),)'.1;# –

L*/9(/46 $(<13(&)46.


1) !-,9,2(&.(/A -'(1A)#.# )5<#+06 Carno )'.#.1,-0 8'1)4.5.#6 &' 712,*. (2-3 %1'6)

2) !-,9,2(&.(/A -'(1A)#.# 8'1),:*&(/%+ ($(,.0.3+ /#8#1%+ &*&.#.(/%+. (2-3 %1'6)

3) !-,9,2(&.(/A -'(1A)#.# :*&(/%+ $(#<31(&)%+ (2-3 %1'6),

4) T1,&$(,1(&)46 .#<E.5.#6 '+D*)(/06 #+.;$1#&56 )' #71(, -1,Q4+ (2-3 %1'6),

EFG6BC:9H=>



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

54


+@HO:>: Atkins – G*&(/,<5)';# 11LNN<ASIA> : PW Atkins"CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6

L10.56 +JR:> & %<J9:> TCG:B8>: 1998ISBN: 960-7309-51-0,?GFCJ> "QG:5:>: 306

+@HO:>: J-;.,)5 :*&(/,<5)';# O LNN<ASIA> : @(#++#/,*$A/56 K. , @(#++#/,*$A/56 T."CG:HFCJ> &@C:>: W0.5 +JR:> & %<J9:> TCG:B8>: 1996ISBN: 9789604312450,?GFCJ> "QG:5:>: 10999


e-class


R+#1.,E+.#( &., e-class


• $(#97F'(6 • '12#&;'6 2(# ., &-;.(

• -1,.'(+4)'+5 C(C9(,21#:;#

• e-class

2OPBBA EFGABCAO@A>

E995+(/A


O*+'/.;)5&5 #-4 C#8),9,2;# &' -1,21#))#.(&)7+'6 'F'.A&'(6 'F#)0+,* ,

&*))'.,<0 &., '12#&.01(, , '12#&;'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

55

2"("+$,/ $


3' ) 3 3 4 6


O.4<,6 .,* )#80)#.,6 ';+#( 5 '(&#2320 &.(6 C#&(/76 #1<76 .56 '-(&.0)56 .56 @'+'.(/06

)7&3 .56 -#1,*&;#&56 /#( /#.#+45&56:

• .56 :E&56 .,* 2'+'.(/,E *9(/,E /#( .,* 2,+($(%)#.,6

• .56 $,)06 .3+ 2,+($;3+

• .56 'F3-*15+(/06 /951,+,)(/4.5.#6

• .56 <13),&3)(/06 8'31;#6 /#( .3+ )5<#+(&)%+ :*9,/#8,1(&),E &' $(#:,1'.(/,E6

,12#+(&),E6

• .3+ $('12#&(%+ .,* /*..#1(/,E /E/9,* /#( .56 '-;$1#&56 .,* 2'+'.(/,E /E/9,*

&.5+ /951,+,)(/4.5.#

• .3+ /#+4+3+ .,* ?7+.'9 /#8%6 /#( .56 ':#1),206 .,*6

• .3+ #1<%+ -,* $(7-,*+ .5 )5 )'+.'9(/0 /951,+,)(/4.5.# • .3+ #1<%+ .56 '-;$1#&56 .3+ -'1(C#99,+.(/%+ -#1#24+.3+ &.5 $(#)41:3&5 .,*

:#(+,.E-,*

• .3+ )5<#+(&)%+ -,* ,$52,E+ &' #+3)#9;'6 .56 /951,+,)(/4.5.#6 &' 2,+($(#/4 /#(

<13),&3)(/4 '-;-'$, /#( .3+ #+.;&.,(<3+ '-($1A&'3+ &.,+ :#(+4.*-,

• .3+ &5)#+.(/4.'13+ (&.,1(/%+ '-(.'*2)A.3+ .56 '-(&.0)56 .56 @'+'.(/06


.=?<8HFCJ 7I<:>

• J(&#2320 &.5 @'+'.(/0

• I $,)0 .,* DNA, 5 :E&5 .,* 2,+($;,*

• @,+($(#/76 )'.#99AF'(6

• JF3-*15+(/0 /951,+,)(/4.5.#

• ?;.3&5 - ?';3&5

• ?'+.'9(/0 /951,+,)(/4.5.#

• =13),&3)(/0 8'31;# .56 /951,+,)(/4.5.#6 , :*9,/#8,1(&)46



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

56

• T1,'/.A&'(6 .3+ #1<%+ .56 )'+.'9(/06 8'31;#6

• G*9,&E+$'.5 /951,+,)(/4.5.#

• T,99#-9A #99594),1:#

• J-;&.#&5

• M+5&(24+# 2,+;$(#

• =13),&3)(/76 #+3)#9;'6

• J(&#2320 &.5 @,+($(3)#.(/0

• @,+4.*-,6 /#( -'1(CA99,+ – J(&#2320 &.5+ J-(2'+'.(/0


1. U)A$'6 #;)#.,6 (3 %1'6)

2. O3)A.(, Barr (3 %1'6)

3. G1,+.(&.51(#/76 #&/0&'(6 (3 %1'6)

EFG6BC:9H=>

$?699A 'A<:LO6C:L, L#8520.1(# @'+'.(/06

!=<FBHI<A !6BK:L , J-;/,*15 L#8520.1(# @'+'.(/06 T958*&)%+


+@HO:>: iGenetics - ?(# ?'+.'9(/0 T1,&722(&5

1LNN<ASIA>: Peter J. Russell"CG:HFCJ> &@C:>: RLRKI?R_LJO JLKUOJVO V. ?TROKPR & OVR U.J.+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2009ISBN: 978-960-88412-8-4,?GFCJ> ")E&U&1: 13003328

+@HO:>: J(&#2320 &.5 2'+'.(/0 1LNN<ASIA>: ?(<#09 @. Z,*/A6 "CG:HFCJ> &@C:>: JLKUOJVO OHR?U!ZI RJ +JR:> & %<J9:> TCG:B8>: R80+# , 2010ISBN: 978-960-351-814-3

,?GFCJ> ")E&U&1: 23093


U( &5)'(%&'(6 .,* )#80)#.,6 ';+#( $(#87&()'6 &., $(#$;/.*, )7&3 .56 -9#.:41)#6 e-class.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

57


H# :*99A$(# .3+ '12#&.51(#/%+ /#( :1,+.(&.51(#/%+ #&/0&'3+ .,* )#80)#.,6 ';+#(

$(#87&()# &., $(#$;/.*, )7&3 .56 -9#.:41)#6 e-class.


K(#97F'(6 , '12#&.51(#/76 #&/0&'(6 , :1,+.(&.01(#.

2OPBBA EFGABCAO@A>

J995+(/A.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

58

BIOXHMEIA I


2 ) 3 3 4 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) 'F,(/';3&5 .3+ :,(.5.%+ )' .(6 C#&(/76 C(,<5)(/76 7++,('6

C) '(&#2320 &' $,)0 -9'(.,*12;# /#( <5)(/76 ($(4.5.'6 C(,),1;3+ )' 7):#&5 &.(6

-13.'Q+'6 /#( .# #)(+,F7#

2) 5 '(&#2320 &.# 7+D*)# /#( .5+ '+D*)(/0 /(+5.(/0 .


.=?<8HFCJ 7I<:>

• H, )41(, .,* +'1,E /#( ,( ($(4.5.'6 .3+ *$#.(/3+ $(#9*)A.3+

• K,)0 /#( 9'(.,*12;# .3+ -13.'Q+%+-

• N+D*)#

• !$#.A+81#/'6

• ",*/9'Q+(/A ,F7#

• Z(-;$(# /#( )')C1#+(/'6 -13.'Q+'6.


1) T#1#&/'*0 !$#.(/%+ K(#9*)A.3+: O +4),6 .56 #1#;3&56 (3 %1'6)

2) T,&,.(/46 -1,&$(,1(&)46 .3+ -13.'\+%+ (?78,$,6 BRADFORD) (2-3 %1'6)

3) T1,&$(,1(&)46 .56 '+D*)(/06 $1#&.(/4.5.#6 .56 :3&:#.A&56 (?78,$,6 .56

-#1#+(.1,:#(+4956) (3 %1'6)

EFG6BC:9H=>

!. 'AL<:7A<6, L#8520.1(#

,. #. ,AHB698 , Z7/.,1#6


+@HO:>: >VU=I?JVR HU?UO V 1LNN<ASIA> : BERG J.M., TYMOCZKO J.L., STRYER L."CG:HFCJ> &@C:>: VHJ-TR"JTVOHI?VRLJO JLKUOJVO LPIHIO +JR:> & %<J9:> TCG:B8>: 2009

ISBN: 978-960-524-190-2,?GFCJ> ")E&U&1: 350



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

59

+@HO:>: Lehninger >#&(/76 R1<76 >(,<5)';#6 1LNN<AS=@>: Nelson D., Cox M.

"CG:HFCJ> &@C:> : JLKUOJVO T. =. TRO=RZVKIO +JR:> & %<J9:> TCG:B8>: 15 7/$./2011ISBN: 9789604892204,?GFCJ> ")E&U&1: 12602324

+@HO:>: 3F:K87=@A 1LNN<AS=@>: Karlson Peter"CG:HFCJ> &@C:> : K. & (. 4$+1-1 &.".+JR:> & %<J9:> TCG:B8>: TCG:B8 : 14 8 ICG./1998ISBN: 96 0-372-013-5,?GFCJ> ")E&U&1: 25250


e-class


K(#.;8'+.#( :3.,.*-;'6 #+A A&/5&5


• $(#97F'(6

• '12#&;'6 2(# ., &-;.(

• -1,.'(+4)'+5 C(C9(,21#:;#

• e-class

2OPBBA EFGABCAO@A>

E995+(/A


O*+'/.;)5&5 #-4 C#8),9,2;# &' -1,21#))#.(&)7+'6 'F'.A&'(6 'F#)0+,* , &*))'.,<0 &.,

'12#&.01(, , '12#&;'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

60

'&#$-,/ '$,#&3$&4&2$-


2 ) 3 3 4 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) I -#1,*&;#&5 .3+ C#&(/%+ #1<%+ .56 G*&(,9,2;#6 /#( 5 #+#2+%1(&5 4.( 5 2+%&5 .56

/*..#1(/06 /#( ),1(#/06 :*&(,9,2;#6 ';+#( &5)#+.(/0 2(# .5 /#.#+45&5 .56 9'(.,*12;#6

.3+ (&.%+ /#( .3+ ,12A+3+ , #99A /#( .56 :*&(,9,2;#6 .3+ &*&.5)A.3+ /#( .56

-#8,27+'(#6 .3+ #&8'+'(%+.C) I /#.#+45&5 .3+ C#&(/%+ )5<#+(&)%+ ,),(4&.#&56 /#( '-(/,(+3+;#6 .3+ /*..A13+

&' $(#/*..#1(/4 /#( -,9*/*..#1(/4 '-;-'$,.

2) I )'97.5 /#( 5 &E2/1(&5 .56 9'(.,*12;#6 $(#:,1,-,(5)7+3+ /*..#1(/%+ .E-3+ .,*

&%)#.,6 /#( 5 &E+$'&5 .,*6 )' .5 &*&.5)(/0 :*&(,9,2;# /#( .5+ 'F'($(/'*)7+5

9'(.,*12;#.

$) I #+#2+%1(&5 .56 &*)C,906 .56 ),1(#/06 C(,9,2;#6 &.5+ /#.#+45&5 C#&(/%+

'13.5)A.3+ -,* #:,1,E+ .5 /*..#1(/0 :*&(,9,2;# )7&# #-4 &*D5.0&'(6 /#( #+#9E&'(6

'-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;#.


.=?<8HFCJ 7I<:>

• ?(/1,,12#+(&),; /#( ?(/1,C(,9,2;#.

• J-(&/4-5&5 .56 ?(/1,C(#/06 W306.

• ?#/1,)41(# ?(/1,,12#+(&)%+.

• L*..#1(/0 K,)0 /#( Z'(.,*12;#: L*..#1(/0 ?,1:,9,2;# , L*..#1(/4 H,;<3)#

T1,/#1*3.%+ , ?'.#/;+5&5 ?(/1,,12#+(&)%+ , K,)76 J-(:#+';#6 /#( N2/9'(&.#

T1,/#1*3.%+ , J+$,&-41(#. M17B5 , J12#&.51(#/0 L#99(712'(# /#( ?'.#C,9(&)46

.3+ ?(/1,,12#+(&)%+.

• ?(/1,C(#/0 REF5&5 : REF5&5 T958*&),E , T'1(C#99,+.(/76 J-($1A&'(6

&.5+ ?(/1,C(#/0 REF5&5 .

• ?(/1,C(#/0 JF79(F5 : T13.42,+5 W30 : U /4&),6 .,* RNA, J+$,&*)C;3&5 ,

O*&.0)#.# >(,9,2(/06 H#F(+4)5&56.

• "7'6 ?78,$,( H#F(+4)5&56: JF'9(/.(/A =1,+4)'.1# , I N++,(# .3+ J($%+.

• @'+(/76 #1<76 .#F(+4)5&56 )(/1,,12#+(&)%+.

• T#F(+4)5&5 C#/.51;3+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

61

• T13.',C#/.01(#: "(.1,-,(5.(/A C#/.01(# , M'(,F'($3.(/A /#(

O($51,F'($3.(/A C#/.01(# , UF'($3.(/A C#/.01(# .,* !$1,24+,* , ?'8#+(4.1,:#

/#( ?'8*94.1,:# , Pseudomonas, UF(/A C#/.01(# , ?5 &*)C(3.(/A #'14C(#

#D3.,$'&)'*.(/A C#/.01(# , J+.'1(/A C#/.01(# , P(/7.&('6 , O-'(1A)#.# ,

J9*.1,:41# C#/.01(# , >#/.01(# )' '/C9#&.0&'(6 , ?*F,C#/.01(# , R +#232(/A T13.',C#/.01(# 8'((/%+ /#( 8';,*.

• Gram (+) C#/.01(#: Staphylococcus, UF*2#9#/.(/A C#/.01(# , Listeria, Bacillus,

Clostridium.

• ?*/,-9A&)#.# , L,1*+,C#/.01(# , C#/.01(# .,* -1,-(,+(/,E ,F7,6 ,

?*/,C#/.01(# , O.1'-.,)E/5.'6.

• L*#+,C#/.01(# , =9#)E$(# , L,+$*9,)(/14C(# , G9#C,C#/.01(# , Cytophaga,

T1A&(+# 8'(,C#/.01(# , O-'(1,<#;.'6 , K'(+4/,//,( , T1A&(+# )5 8'((/A C#/.01(# ,

!-'18'1)4:(9# )' -1%()'6 :*9,2'+'.(/76 $(#/9#$%&'(6.• T#F(+4)5&5 R1<#;3+: L1'+#1<#(3.(/A , J*1*#1<#(3.(/A , T#1#2320

?'8#+;,* #-4 ?'8#+(,24+#.

• H#F(+4)5&5 J*/#1*3.(/%+ U12#+(&)%+ (J*/#1*3.%+): J-(&/4-5&5 .56

@'+'.(/06 .3+ J*/#1E3+ , T13.4D3# , ?E/5.'6 , GE/5 .

• N9'2<,6 ?(/1,C(#/06 REF5&56: R+.()(/1,C(#/,; T#1A2,+.'6.

• T#8,27+'&5 ?(/1,,12#+(&)%+-H,F;+'6.

• >(,.'<+,9,2(/76 J:#1),276 ?(/1,,12#+(&)%+.

• V,9,2;#: @'+(/76 ($(4.5.'6 .3+ (%+ , :E&5 .,* (,&%)#.,6 , -,&,.(/46

-1,&$(,1(&)46 .3+ (%+ , ((/46 -,99#-9#&(#&)46 – -1,&/4995&5 /#( $(';&$*&5 ,

C#/.51(,:A2,( , D3(/,; (,; , 1'.1,Q,; , (,'($0 /#( -13.'\+'6 prion.


1. R&5-.(/76 )78,$,( '12#&;#6 &.5 ?,1(#/0 ?(/1,C(,9,2;# , -#1#&/'*0

81'-.(/%+ )7&3+ , #-,&.';13&5 (2h).

2. L#8#176 /#99(712'('6: T#1#&/'*0 *21%+ /#( &.'1'%+ /#99('12'(%+ (2h).

3. T1,&$(,1(&)46 #1(8),E C#/.51;3+ )' .5+ )78,$, .3+ $(#$,<(/%+ #1#(%&'3+.

R-,)4+3&5 2#9#/.(/%+ C#/.51;3+ #-4 2#9#/.,)(/A -1,Q4+.# (2h).

4. J*#(&85&;# )(/1,C;3+ &.# #+.(C(,.(/A. R+.()(/1,C(#/0 $1A&5 #(871(3+ '9#;3+

(2h).

5. ?,+(),-,;5&5 /#( <1%&5 /#.A Gram. ?(/1,&/,-(/0 -#1#.015&5 . N9'2<,6

)(/1,C(#/06 <931;$#6 &.4)#.,6 (2h).

,+.(/76 C#8)($%&'(6 /#( $;#*9,( (4+.3+ - K('271&()'6 )')C1A+'6 - K*+#)(/A

)')C1A+56 K5)(,*12;# /#( $(A$,&5 $*+#)(/,E $1A&56

EFG6BC:9H=>

1) $. ,:L<C:LH6>, E-;/,*1,6 L#8525.06 J:#1),&)7+56 >(,.'<+,9,2;#6. 2) AFC. %O@KOFA , J-;/,*1,6 L#8520.1(# ?,1(#/06 R+,&,C(,9,2;#6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

62


+@HO:>: Brock, >(,9,2;# .3+ ?(/1,,12#+(&)%+ ,H4),6 I

1LNN<ASIA>: M. T. ?adigan, J. M. Marinko, J. Parker

"CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 L10.56 +JR:> & %<J9:> TCG:B8>: L10.5 , 2005ISBN: 960-524-199-4,?GFCJ> ")E&U&1: 366

+@HO:>: Brock, >(,9,2;# .3+ ?(/1,,12#+(&)%+ ,H4),6 II

1LNN<ASIA>: M. T. ?adigan, J. M. Marinko, J. Parker"CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 L10.56 +JR:> & %<J9:> TCG:B8>: L10.5 , 2007ISBN: 960-524-199-5,?GFCJ> ")E&U&1: 367

+@HO:>: ?(/1,C(,9,2;# & ?(/1,C(#/0 H'<+,9,2;# 1LNN<ASIA>: @. R22'906 "CG:HFCJ> &@C:>: J/$4&'(6 O.#),E95 +JR:> & %<J9:> TCG:B8>: R80+# , 2007ISBN: 978-960-351-717-7,?GFCJ> ")E&U&1: 22904

+@HO:>: ?(/1,C(,9,2;# 1LNN<ASIA>: O. L,9(A56 "CG:HFCJ> &@C:>: University Studio Press A.E.

+JR:> & %<J9:> TCG:B8>: R80+# , 2001ISBN: 978-960-12-0308-9,?GFCJ> ")E&U&1: 17401


+@HO:>: O5)'(%&'(6 ?,1(#/06 ?(/1,C(,9,2;#6 1LNN<ASIA>: V. L,*1/,*.A6 +JR:> & %<J9:> TCG:B8>: H)0)# ?,1(#/06 >(,9,2;#6 & @'+'.(/06 ,

K5),/1;.'(, T#+/)(, M1A/56 , 2010.


+@HO:>: J12#&.51(#/76 R&/0&'(6 ?,1(#/06 ?(/1,C(,9,2;#6

1LNN<ASIA>: V. L,*1/,*.A6 +JR:> & %<J9:> TCG:B8>: H)0)# ?,1(#/06 >(,9,2;#6 & @'+'.(/06 ,

K5),/1;.'(, T#+/)(, M1A/56 , 2010.


1. K(#97F'(6 &' #):(87#.1,.2. =10&5 e-class.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

63

3. J12#&.51(#/76 #&/0&'(6.

4. G1,+.(&.01(#.

5. K(#97F'(6 #-4 -1,&/'/95)7+,*6 ,)(95.76 ('-(&.0),+'6 , &.'97<5 '-(<'(10&'3+ &

C(,)5<#+;#6 , /9-).


1. J+$(A)'&5 -14,$,6 (21#-.0 'F7.#&5 ).

2. J12#&.51(#/76 #+#:,176.

3. H'9(/76 21#-.76 'F'.A&'(6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

64

3$&4&2$- ,)++-#&)


2’ ) 4 3 5 7


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) 5 /#.#+45&5 .3+ )5<#+(&)%+ -,* $(7-,*+ .(6 9'(.,*12;'6 .,* /*..A1,*

C) 5 /#.#+45&5 .3+ C#&(/%+ #1<%+ .56 &*)-'1(:,1A6 , :*&(,9,2;#6 /#( #9959'-;$1#&56

.3+ /*..A13+ )' ., -'1(CA99,+ .,*6 , &' )(/1,&/,-(/4 /#( ),1(#/4 '-;-'$,.

2) 5 '/.;)5&5 .3+ ,),(,.0.3+ /#( .3+ $(#:,1%+ )'.#FE .3+ $(#:,1'.(/%+ .E-3+ /*..A13+

$) 5 )'2#9E.'15 '-#:0 )' .5+ &E2<1,+5 C(C9(,21#:;#


• R+A9*&5 $,)06 /#( 9'(.,*12;#6 .3+ /*..A13+-?'8,$,9,2;#

o G3.,+(/0 ?(/1,&/,-;# , ?(/1,&/,-(/76 .'<+(/76 :8,1(&),E

o I9'/.1,+(/0 ?(/1,&/,-;#

o R+,&,-/*..#1,<5)';#

o L9#&)A.3&5 /*..A1,* , =13)#.,21#:;#

o I9'/.1,:415&5

o L*..#1,/#99(712'('6

• T1,/#1*3.(/A , '*/#1*3.(/A /E..#1# , (,; , /*..#1(/A ,12#+;$(#- $,)0 /#( 9'(.,*12;#

.,*6 (-*10+#6 , )(.,<4+$1(# , JK , Golgi, <931,-9A&.'6 , *-'1,F'(&%)#.# , 9*&,&%)#.#)

• T*15+(/46 &/'9'.46 , -*15+(/,; -41,(

• OE+8'&5 /#( )'.#.1,-0 -13.'Q+%+ , .14-,6 9'(.,*12;#6 -13.'Q+%+

• J+$,/*..A1(# K(#)'1;&)#.# /#( )'.#:,1A: -*15+(/0 -/*..#1,-9#&)#.(/0 )'.#:,1A

• J+$,/*..A1(# K(#)'1;&)#.# /#( )'.#:,1A: $(#9,20 , $(#/;+5&5 /#( 7//1(&5

-13.'Q+%+ , '+$,/*..A13&5 , 'F3/*..A13&5

• L*..#1(/76 )')C1A+'6: OE&.#&5 /#( $,)0 .3+ C(,)')C1#+%+ -K(#-'1#.4.5.#

)')C1#+%+ - T13.'\+'6 )'.#:,1';6 - V,+.(/,; $;#*9,(

• L*..#1,&/'9'.46: '+$(A)'&# (+;$(# , )(/1,&395+;&/,( , +5)A.(# #/.;+56 , )*Q/0

&*&.,90

• L*..#1(/0 $(#;1'&5 , )';3&5 , /*..#1(/46 /E/9,6 , 1E8)(&5 /*..#1(/,E /E/9,*

• L*..#1(/0 201#+&5 /#( /*..#1(/46 8A+#.,6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

65

• L*..#1(/0 '-(/,(+3+;# /#( $(#/*..#1(/,; &E+$'&),(

• R1<72,+# /E..#1# , /#1/(+(/4 /E..#1, , D30 /#( 8A+#.,6 .3+ /*..A13+ &' (&.,E6


1. M;.3&5 (3 %1'6)

2. `&)3&5 -D3Q/4 /#( :*.(/4 /E..#1, (2 %1'6)

3. L*..#1(/0 L9#&)A.3&5 , K(#<31(&)46 *-,/*..#1(/%+ ,12#+($;3+ (3 %1'6)

4. I9'/.1,:415&5 -13.'Q+%+ &' -5/.0 SDS -,9*#/1*9#)($;,* (SDS – PAGE), <1%&5 )'

Coomasie blue ( 4 %1'6)

5. ?'.#:,1A .3+ -13.'Q+%+ #-4 -5<.5 SDS -,9*#/1*9#)($;,* &' )')C1A+5

+(.1,/*..#1;+56 (59'/.1,)'.#:,1A – electroblotting) (3 %1'6)

6-7. R+A9*&5 -13.'Q+%+ )' #+,&,#-,.E-3&5 – Western blotting (6 %1'6)

EFG6BC:LBA

'A<@A ,JSSA, R+#-951%.1(# L#8520.1(# L*..#1(/06 >(,9,2;#6


+@HO:>: >#&(/76 R1<76 L*..#1(/06 >(,9,2;#6 1LNN<ASIA>: Alberts B.,Bray D.,Hopkin K.,Johnson A.,Lewis

J.,Raff M.,Roberts K.,Walter P."CG:HFCJ> &@C:>: Broken Hill Publishers+JR:> & %<J9:> TCG:B8>: 2006

ISBN: 978-960-489-276-1,?GFCJ> ")E&U&1: 13256944

+@HO:>: B(,9,2;# L*..A1,* 1LNN<ASIA>: >ROVZIO ?RP?RPRO & ?RPVR

ZR?TPUTU!ZU!-?RP?RPR "CG:HFCJ> &@C:>: H*-41#)# +JR:> & %<J9:> TCG:B8>: 2005ISBN: 960-7620-13-5

,?GFCJ> ")E&U&1: 6

+@HO:>: 3F:O:N@A ,LHH6<:L

1LNN<ASIA> :

'A<NA<@H8> 4:LC6>

%

.,?GFCJ> 3FXO@:L BH:9 "QG:5:: 25249TCG:B8 : 4 8 ICG./2004ISBN: 960-372-077-1+QR:>: 1QNN<A77A EFAMIH8> ("CGJH8>): K. & (. 4$+1-1 &.".

+@HO:>: #LM7FBHFC:@ 78KA9FB7 s:@ CLHHA<FCD> O=FH:L<N@A>

,?GFCJ> 3FXO@:L BH:9 "QG:5:: 17508TCG:B8 : 18 ICG./20061LNN<AS=@>: .?7JR:LO:> 2=P<NF:> (.ISBN: 978-960-12-1549-5+QR:>: 1QNN<A77A EFAMIH8> ("CGJH8>): University Studio Press -.".



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

66


U( -#1,*&(A&'(6 .3+ $(#97F'3+ #+#1.%+.#( (&' ),1:0 pdf) &., (&.4.,-,

.59'/-#;$'*&56 (e-class) .,* )#80)#.,6.


+@HO:>: J12#&.51(#/76 #&/0&'(6 >(,9,2;#6 L*..A1,* 1LNN<ASIA>: L4::# ?#1;# +JR:> & %<J9:> TCG:B8>: H?>@ , KTM , R9'F#+$1,E-,95 2013


K($#/.(/A C,580)#.# -&E221#)# '-(9,206 /#( :*99A$(, '12#&.51(#/%+ #&/0&'3+), video,.# ,-,;# #+#1.%+.#( &., e-class .,* )#80)#.,6.

R229(/0 C(C9(,21#:;#- #+.;.*-# .3+ '+ 9423 &*221#))A.3+ C1;&/,+.#( &.5 C(C9(,80/5 ,

/#( -#17<,+.#( )7&3 .,* e-class.

J/-#($'*.(/76 &'9;$'6 $(#$(/.E,* -,* &<'.;D,+.#( )' ., #+.(/';)'+, .,* )#80)#.,6

J-(&.5),+(/A A181# -,* &<'.;D,+.#( )' ., #+.(/';)'+, .,* )#80)#.,6 /#(

<15&(),-,(,E+.#( 2(# -1,#(1'.(/76 '12#&;'6

2OPBBA EFGABCAO@A>

J995+(/A , ,1(&)7+# &*221A)#.# /#( C(C9(,21#:(/A A181# &.# #229(/A


JF7.#&5 21#-.0 &., .79,6 .,* 'F#)0+,* (87)#.# -,99#-906 '-(9,206 , /#( 87)#.#

#+A-.*F56 , 80% .56 C#8),9,2;#6)

@1#-.0 'F7.#&5 &., .79,6 .56 '12#&.51(#/06 A&/5&56 20% .56 C#8),9,2;#6

T1,#(1'.(/0 -1,:,1(/0 -#1,*&;#&5 '12#&;#6 (&*+*-,9,2(&)46 &.5 C#8),9,2;# .,*

)#80)#.,6 )' -1,&#EF5&5 10%



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

67

EI1-2*2/ 1+/( +"%(&4&2$- '&#$-,/1 3$&4&2$-1


2’ ) 3 0 4 6


O.4<,( .,* )#80)#.,6 ';+#(:

#) N# 2+31;&,*+ ,( :,(.5.76 .(6 #1<76 &.(6 ,-,;'6 &.51;D,+.#( ,( C#&(/76 .'<+(/76 .56

?,1(#/06 >(,9,2;#6

C) "# /#.#+,0&,*+ .(6 ':#1),276 .3+ C#&(/%+ .'<+(/%+ .56 ?,1(#/06 >(,9,2;#6 &.5

>#&(/0 /#( J:#1),&)7+5 N1'*+#

2) "# /#.#+,0&,*+ .(6 -1#/.(/76 ':#1),276 .3+ C#&(/%+ .'<+(/%+ .56 ?,1(#/06 >(,9,2;#6

&' $(A:,1,*6 .,)';6 4-36 5 !2';# , 5 @'312;# /9-.


.=?<8HFCJ 'I<:>

E 19282$ > : T $ ?1@<"$ .

1. J(&#2320 &.# 7+D*)#.

2. T'1(,1(&.(/A 7+D*)#.

3. U( T,9*)'1A&'6 .,* DNA /#( 5 <10&5 .,*6 &.5 &0)#+&5 DNA (&0)#+&5 )' .*<#;,*6

'//(+5.76 /#( &0)#+&5 )' )'.A:1#&5 '2/,-06).

4. T,9*)'1A&'6 .,* RNA.

5. Z(2A&'6 .,* DNA.6. ",*/9'A&'6.

7. L(+A&'6 & G3&:#.A&'6 .,* DNA /#( 5 <10&5 .,*6 &.5 &0)#+&5 DNA.

8. N+D*)# #+#&*+$*#&),E (cre, FLP recombinases).

9. T13.'Q+A&5 L .

A19282$ >> : 4'&)$'<B2()C D<D2#"$2$ ),B1&;&.8D8* .

1. O.,(<';# C(,9,2;#6 .,* C#/.51;,* A . coli.

2. G,1';6 /93+,-,;5&56 (-9#&)($(#/,; , (Q/,; :,1';6 , :#2');$(# , !RC /#( >AC).

A19282$ >>> : %?E&7&( $;&"91BD8* & "0,?28* 1&<),0F)=1 &G?B1 .

1. ?78,$,( #-,)4+3&56 DNA (-9#&)($(#/,E , (Q/,E , 2,+($(3)#.(/,E).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

68

2. ?78,$,( #-,)4+3&56 RNA (,9(/,E /#( poly A-RNA).

3. ?78,$,( )'97.56 .,* DNA /#( .,* RNA.

4. I .'<+(/0 .56 59'/.1,:415&56 (-5/.%)#.# #2#14D56 /#( -,9*#/1*9#);$56).

5. I .'<+(/0 .56 )'.#:,1A6 &' )')C1A+'6 (Southern /#( Northern blotting).

6. E($(/76 )78,$,( #+A9*&56 .,* RNA (-1,&.#&;# #-4 RNAA&5 , '-7/.#&5 '//(+5.0 ).A19282$ > V: H "?E&7&* 28* PCR.

1. U )5<#+(&)46 .56 )'84$,* PCR.

2. E-(9,20 '//(+5.%+: I -(, /1;&()5 -#1A)'.1,6 .56 PCR.

3. J/:*9(&)7+,( '//(+5.76.

4. K 93+,-,;5&5 .3+ -1,Q4+.3+ .56 PCR.

5. R9*&($3.0 #+.;$1#&5 -,9*)'1A&56 )'(,E)'+56 8'1),/1#&;#6 *C1($,-,;5&56 (touch-down

PCR).

6. R9*&($3.0 #+.;$1#&5 -,9*)'1A&56 )' 8'1)0 7+#1F5 (hot start PCR).7. J-A9959, PCR (nested PCR).

8. R+A&.1,:5 PCR (inverse PCR).

9. PCR #+.;&.1,:56 )'.#21#:06 (Reverse Transcription PCR / RT-PCR).

10. PCR $(#:,1(/06 7/:1#&56 (Differential Display PCR).

11. SELEX (Systematic Evolution of Ligands by Exponential Enrichment).

12. In vivo footprinting.

13. H, PCR &.5+ #+A9*&5 -,9*),1:(&)%+.

14. PCR -1#2)#.(/,E <14+,* (real time PCR).

A19282$ V: E H'0D8 28* ;'B2&7(C2$G8* 2&< DNA (DNA sequencing)

1. JE1'&5 .56 #9959,*<;#6 .,* DNA )' .5 )78,$, Maxam - Gilbert.

2. JE1'&5 .56 #9959,*<;#6 .,* DNA )' .5 )78,$, Sanger (+ automated PCR sequencing).

3. Pyrosequencing.

A19282$ VI: I$2$D)0<# +(J,(&E8)=1

1. @,+($(3)#.(/76 C(C9(,80/'6.

2. cDNA C(C9(,80/'6: C#&(/A &.A$(# &.5+ /#.#&/'*0 cDNA C(C9(,85/%+ , full length cDNA cloning,

C(C9(,80/'6 7/:1#&56 , -1,&#+#.,9(&)7+5 /93+,-,;5&5 .

EFG6BC:9H=>

2. 1C6XG8> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6.


+@HO:>: R+#&*+$*#&)7+, DNA1LNN<ASIA>: Watson D.A. /# "CG:HFCJ> &@C:>: R/#$5)#Q/76 '/$4&'(6 V ?-A&$1# & OVR UJ +JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-5-3,?GFCJ> ")E&U&1: 2625.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

69

+@HO:>: J12#&.51(#/,; *-,9,2(&),; &.(6 C(,9,2(/76 '-(&.0)'6

1LNN<ASIA>: Lisa Seidman"CG:HFCJ> &@C:>: R/#$5)#Q/76 '/$4&'(6 V ?-A&$1# & OVR UJ

+JR:> & %<J9:> TCG:B8> 15 2010ISBN: 978-960-88412-9-1 ,?GFCJ> ")E&U&1: 5319


+@HO:>: T#1,*&(A&'(6 )#80)#.,6 J(&#2320 &.5+ H'<+,9,2;# ?,1(#/06 >(,9,2;#6

1LNN<ASIA>: @. O/AC$56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010 –


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &.,

)A85)# <15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, ,

:,(.5.06 $'+ #-,/.A )4+, 2+%&'(6 , #99A #+#-.E&&'( /#( (/#+4.5.'6 -,* .,* '-(.17-,*+

+# &<'$(AD'( -'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&,

/#( )' ., $($A&/,+.#.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

70

'&#$-,/ 3$&4&2$- $


2’ ) 4 1 5 7


- "# /#.#+,0&'( , :,(.5.06 C#&(/76 7++,('6 .56 ?,1(#/06 >(,9,2;#6 -,* &<'.;D,+.#( )' .5 1,0 .56 -951,:,1;#6 /#( .5 :E&5 .,* 2'+'.(/,E *9(/,E.

- "# #+#-.EF'( (/#+4.5.'6 #+A9*&56 /#( /1(.(/06 &E+8'&56.

- "# #+.(95:8'; 4.( &5)#&;# 7<'( 5 /#.#+45&5 .3+ )5<#+(&)%+ $;+,+.#6 7):#&5 &.#

:#(+4)'+# 1E8)(&56 , 8'31%+.#6 0&&,+,6 &5)#&;#6 .5+ #-,&.08(&5 2+%&'3+ /#( 9'-.,)'1'(%+.

- "# )A8'( .(6 C#&(/76 #1<76 .56 )'.#21#:06 /#( .3+ 1*8)(&.(/%+ )5<#+(&)%+ &.,*6

-1,/#1*%.'6 /#( +# #+.(-#1#CA9'( .5 $,)0 .,* 2'+'.(/,E *9(/,E .,*6 )' #*.0 .3+

'*/#1*3.%+.

- "# $5)(,*1258'; &., :,(.5.0 7+# #;&85)# 8#*)#&),E )-1,&.A &.5+ -,9*-9,/4.5.# ,,),1:(A /#( #-,.'9'&)#.(/4.5.# .3+ ),1(#/%+ )5<#+(&)%+ -,* )'9'.A.


H, )A85)#

,12#+%+'.#(

&.(6

-#1#/A.3

8')#.(/76

'+4.5.'6

:

1. J(&#232(/76 7++,('6. I 1,0 .56 2'+'.(/06 -951,:,1;#6. I :E&5 .,* 2,+($;,*. I $,)0 .,*

2'+'.(/,E *9(/,E. I #99#20 .,* 2'+'.(/,E *9(/,E ()'.#99AF'(6). U 2'+'.(/46 /%$(/#6. cis -

K1#&.(/A &.,(<';# /#( trans -$1#&.(/,; -#1A2,+.'6.

2. H, $(#/,-.4)'+, 2,+;$(,. JF4+(# /#( (+.14+(#.

3. I )'.#21#:0 &.,*6 -1,/#1*3.(/,E6 ,12#+(&),E6.

4. H, ,-'14+(,.

5. P*8)(&.(/A /*/9%)#.# &.# C#/.01(#.

6. O.1#.52(/76 :A23+. Z*.(/46 /E/9,6 /#( 9*&(2,+;#.7. I $,)0 .,* 2'+'.(/,E *9(/,E &.,*6 '*/#1*3.(/,E6 ,12#+(&),E6. H, <13)4&3)#.

8. I $,)0 /#( 5 ,12A+3&5 .,* 2'+'.(/,E *9(/,E &' +,*/9',&%)#.#.

EFG6BC?9

#ASADO 1A9GAOHVJR:LO:>, R+#-9513.06 L#8525.06 ?,1(#/06 >(,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

71


+@HO:>: Genes VIIV 1LNN<ASIA>: Lewin"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J

+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2004ISBN: 960-88412-2-6,?GFCJ> ")E&U&1: 13003327

+@HO:>: +: ,QHHA<:: 'FA ':<FACD !<:BINNFB81LNN<ASIA> : Geoffrey M. Cooper & Robert E. Hausman"CG:HFCJ> &@C:>: -CAG87AYCI> "CGJB=F> $. 'R6BG<A &

1$- &." +JR:> & %<J9:> TCG:B8>: -O=5A9G<:QR:O8 , 58 /2011ISBN: 978-960-99895-8-9,?GFCJ> ")E&U&1: 33133232


LA8' $($#/.(/0 '+4.5.# -#1,*&(AD'.#( /#( #+#9E'.#( &., #):(87#.1,. =15&(),-,(,E+.#(

-#1,*&(A&'(6 $(#:#+'(%+ (powerpoint) /#( &<'.(/A C;+.',. K;+'.#( 7):#&5 &.5 $(#.E-3&5

'13.5)A.3+ .# ,-,;# /#9,E+.#( +# #-#+.0&,*+ )' $(#9'/.(/0 $(#$(/#&;# ,( :,(.5.76 ,

&.51(D4)'+,( &.(6 C#&(/76 #1<76 -,* #+#-.E<85/#+ &., )A85)#. O., .79,6 /A8' '+4.5.#6

/#.#1.;D'.#( 9;&.# )' .# /E1(# &5)';# -,* #+#-.E<85/#+ /#( #+#:71,+.#( .#

&*)-'1A&)#.#. O.# :1,+.(&.51(#/A )#80)#.# '-#+#9#)CA+,+.#( .# /E1(# &5)';# )7&#

#-4 .5+ #+A9*&5 -'(1#)#.(/%+ -1,&'22;&'3+ , ':#1),2%+ 0 -'1(-.%&'3+ #&8'+'(%+ -,*

&<'.;D,+.#( )' ., ),1(#/4 )5<#+(&)4 &.,+ ,-,;, #+#:'14)#&.'. I )78,$,6 #F(,9425&56

<15&(),-,(';.#( /#( 36 )#85&(#/4 '12#9';, $(4.( '/-#($'E,+.#( ,( :,(.5.76 &.5+ /1(.(/0

&/7B5 /#( &.5 9,2(/0 #F(,9425&5 '13.5)A.3+ -,99#-9%+ '-(9,2%+. U( :,(.5.76

-1,&/#9,E+.#( +# $(#.*-%&,*+ 87&'(6 , #-4B'(6 /#( '13.0)#.# &<'.(/A )' .,

-'1('<4)'+, .,* )#80)#.,6. ?' /A8' '*/#(1;# '+8#11E+'.#( , $(A9,2,6 /#( 5 &*))'.,<0

.3+ :,(.5.%+ &.5+ -,1';# -,* #/,9,*8';.#( 2(# +# /#.#90F,*)' &.# .'9(/A

&*)-'1A&)#.#.

'IM:G:F A5F:OJN8B8> – BAM7:OJN8B8

@(# .5+ #F(,9425&5 9#)CA+'.#( *-4B5 5 '-;$,&5 &' -1,#(1'.(/0 21#-.0 -14,$, (/#.A 20%)

':4&,+ '-(.'*<8'; )(# &*2/'/1()7+5 '9A<(&.5 '-;$,&5 /#( , C#8)46 .3+ *-,<1'3.(/%+

21#-.%+ 'F'.A&'3+ /#.A .5+ 'F'.#&.(/0 -'1;,$,. O*+0836 $;+,+.#( 7F.1# ),+A$'6 &'

:,(.5.76 -,* #+#9#)CA+,*+ '8'9,+.(/A '12#&;'6 (-.<. -#1,*&(A&'(6 &*2/'/1()7+3+

8')A.3+ #-4 .5+ .17<,*&# C(C9(,21#:;#), #+A9,2# )' .5+ #-4$,&0 .,*6. O.# 87)#.# .3+

'F'.A&'3+ -'1(9#)CA+,+.#( '13.0)#.# -,* &*D5.085/#+ &., #):(87#.1, /#.A .5

$(A1/'(# .3+ )#85)A.3+ 0 .3+ :1,+.(&.51;3+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

72

2OPBBA EFGABCAO@A>

J995+(/A. T1,#(1'.(/76 '12#&;'6/-#1,*&(A&'(6 )-,1'; +# &.51;D,+.#( /#.A -'1;-.3&5

&' F'+4293&&5 C(C9(,21#:;# (#229(/A), /*1;36 &' -13.4.*-'6 $5),&('E&'(6 '1'*+5.(/%+

#-,.'9'&)A.3+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

73

3$&%/'"$- $$


2ZZ

) 4 3 5 6


U( &.4<,( .,* )#80)#.,6 ';+#( 5 '(&#2320 :#) &.(6 &*D'*2)7+'6 '+D*)(/A /#.#9*4)'+'6 #+.($1A&'(6 .,* #+81%-(+,* ,12#+(&),E -,*

,$52,E+ &.5+ #-#1#;.5.5 2(# .5+ '-(C;3&0 .,* -#1#2320 '+712'(#6 , #+#232(/,E

$*+#)(/,E /#( C(,&*+8'.(/%+ ),1;3+.

C) )'97.5 .56 1E8)(&56 .3+ /E1(3+ )'.#C,9(/%+ ,$%+ /#( .,* )'.#C,9(/,E profile

$(#:413+ (&.%+ , /#( .,* -36 #*.76 #+.(/#.1,-.1;D,*+ ., (&,DE2(, '+712'(#6 -,*

<1'(AD'.#( (, A+813-,6) /#( .5+ /#.A&.#&5 .56 *2';#6 .,*.


U )'.#C,9(&)46 .56 29*/4D56 /#( .3+ *$#.#+81A/3+

• U LE/9,6 .,* Krebs /#( ,F'($3.(/0 :3&:,1*9;3&5

• U )'.#C,9(&)46 .3+ 9(-%+ (C(,&E+8'&5 /#( C-,F';$3&5 )

• U )'.#C,9(&)46 .3+ #)(+,F73+ (/E/9,6 .56 ,*1;#6)

• I ,9,/9013&5 .,* )'.#C,9(&),E (1E8)(&5 &' '-;-'$, (&.,E /#( &' '-;-'$, ,12#+(&),E.

J12#&.51(#/76 R&/0&'(6

1) R&/5&5 &<'.(/0 )' ., )'.#C,9(&)4 .56 29*/4D56 0 *-,9,2(&.(/76 #&/0&'(6 &.,

'12#&.01(, (2 %1'6).

2) L#8#1(&)46 -13.'Q+%+ : <13)#.,21#:;# ),1(#/06 $(085&56 (3 %1'6)

3) UF'($,#+#232(/A 7+D*)# (3 %1'6).

EFG6BC:9H=> MAL<:7A<6 !., L#8520.1(#

,AHB698 ,.#. , Z7/.,1#6


+@HO:>: >VU=I?JVR HU?UO V 1LNN<ASIA> : BERG J.M., TYMOCZKO J.L., STRYER L."CG:HFCJ> &@C:>: VHJ-TR"JTVOHI?VRLJO JLKUOJVO LPIHIO +JR:> & %<J9:> TCG:B8>: 2009ISBN: 978-960-524-190-2

,?GFCJ> ")E&U&1: 350



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

74

+@HO:>: Lehninger >#&(/76 R1<76 >(,<5)';#6 1LNN<AS=@>: Nelson D., Cox M. "CG:HFCJ> &@C:> : JLKUOJVO T. =. TRO=RZVKIO +JR:> & %<J9:> TCG:B8>: 15 7/$./2011 ISBN: 9789604892204

,?GFCJ> ")E&U&1: 12602324

+@HO:>: 3F:K87=@A 1LNN<AS=@>: Karlson Peter"CG:HFCJ> &@C:> : K. & (. 4$+1-1 &.".+JR:> & %<J9:> TCG:B8>: TCG:B8 : 14 8 ICG./1998ISBN: 96 0-372-013-5,?GFCJ> ")E&U&1: 25250


e-class


EFAH@M=9HAF S?H:HLR@=> A96 6BC8B8


• $(#97F'(6

• '12#&;'6 2(# ., &-;.(

• -1,.'(+4)'+5 C(C9(,21#:;#

• e-class


O*+'/.;)5&5 #-4 C#8),9,2;# &' -1,21#))#.(&)7+'6 'F'.A&'(6 'F#)0+,* , &*))'.,<0 &.,

'12#&.01(, , '12#&;'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

75

0)1$&4&2$-


E ) 4 3 5 7


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) 5 -#1,*&;#&5 /#( 5 /#.#+45&5 .3+ C#&(/%+ #1<%+ .56 G*&(,9,2;#6 /#( .3+ )5<#+(&)%+ -,*

.(6 $(7-,*+. N):#&5 $;+'.#( &., -36 ,( ),1(#/,; )5<#+(&),; /#( ,( /*..#1(/76 9'(.,*12;'6

)7&3 &#:%+ #9959,*<(%+ #(.(,9,2(/%+ &*+$7&'3+ ,9,/951%+,+.#( 2(# .5 &*+.,+(&)7+5

9'(.,*12;# .3+ &*&.5)A.3+ /#( .5+ ,),(4&.#&5 .,* ,12#+(&),E.

C) I /#.#+45&5 .3+ C#&(/%+ )5<#+(&)%+ ,),(4&.#&56 /#( '-(/,(+3+;#6 .3+ /*..A13+ &' $(#/*..#1(/4 /#( -,9*/*..#1(/4 '-;-'$,.

2) I )'97.5 /#( 5 &E2/1(&5 .56 9'(.,*12;#6 $(#:,1,-,(5)7+3+ /*..#1(/%+ .E-3+ .,* &%)#.,6

/#( 5 &E+$'&5 .,*6 )' .5 &*&.5)(/0 :*&(,9,2;# /#( .5+ 'F'($(/'*)7+5 9'(.,*12;#.

$) 5 /#.#+45&5 .3+ 9'(.,*12(%+ .,* +'*1(/,E , )*Q/,E , /#1$(#22'(#/,E , #+#-+'*&.(/,E ,

+':1(/,E , -'-.(/,E /#( #+#-#1#232(/,E &*&.0)#.,6 .3+ 859#&.(/%+.

') 5 /#.#+45&5 .56 '+$o/1(+(/06 1E8)(&56 .,* )'.#C,9(&),E /#( .56 #+A-.*F56.

&.) 5 #+#2+%1(&5 .56 &*)C,906 .56 ),1(#/06 C(,9,2;#6 &.5+ /#.#+45&5 C#&(/%+ '13.5)A.3+

-,* #:,1,E+ .5 :*&(,9,2;# 859#&.(/%+ )7&# #-4 &*D5.0&'(6 /#( #+#9E&'(6 '-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;#.


.=?<8HFCJ 7I<:>

M'315.(/4 )71,6

1.J(&#2320 - M')'9(%$'(6 7++,('6 &.5 G*&(,9,2;# - K(#/;+5&5 ),1;3+ )7&3 )')C1#+%+

2.. O*&.0)#.# ,),(,&.#.(/,E '972<,* /#( )5<#+(&),; '972<,* .56 /*..#1(/06 9'(.,*12;#6

)7&3 )5+*)#.,:413+ ),1;3+

3. "'*1(/46 (&.46 /#( $*+#)(/A )')C1A+56 - O*+#-.(/0 $(#C;C#&5 4.O/'9'.(/76 )*Q/76 ;+'6 - ?,1(#/,; )5<#+(&),; )*Q/06 &*&.,906 - J+'125.(/0 .,* &/'9'.(/,E

)*46

5.Z';'6 )*Q/'6 ;+'6 - ?,1(#/,; )5<#+(&),; )*Q/06 &*&.,906 - N9'2<,6 .56 /;+5&56 .,*

&%)#.,6

6. L#1$(#/46 )*6- O*+.,+(&)46 /#1$(#/,E -#9),E - /#1$(#/0 -#1,<0

7. R22'(#/4 &E&.5)# - Z'):(/4 &E&.5)#

8.U12A+3&5 .,* #+#-+'*&.(/,E &*&.0)#.,6 - ?5<#+(/0 .56 #+#-+,06 - R+.#99#20 #'1;3+ &.(6

/*B'9;$'6 /#( &.,*6 (&.,E6 - L,1'&)46 #(),&:#(1;+56 9. R'1(&)46 /#( 1E8)(&5 ,F',C#&(/06 (&,11,-;#6 - N9'2<,6 .56 9'(.,*12;#6 .56 #+#-+,06



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

76

10. "':1(/76 $('12#&;'6: K(085&5 - J-#++#14:5&5 - N//1(&5 - R-7//1(&5

11. "':1(/0 1E8)(&5 ,),(4&.#&56 +'1,E /#( #+412#+3+ (4+.3+ ("# /#( L )

12. X12#+# - K1A&.'6 .56 ,),(4&.#&56 #&C'&.;,* /#( ,1),+(/46 79'2<,6

13. PE8)(&5 /#( 9'(.,*12;'6 .3+ ,12A+3+ .,* 2#&.1'+.'1(/,E &*&.0)#.,6 (-7B5 /#(

#-,14:5&5 .1,:%+)14. J+$,/1(+(/46 /#( +'*1(/46 79'2<,6 /#( ,9,/9013&5 .,* )'.#C,9(&),E ,12#+(/%+ '+%&'3+

15. N9'2<,6 .56 #EF5&56 /#( .56 #+A-.*F56 - R*F5.(/76 ,1),+(/76 '-($1A&'(6

16. R+#-#1#232(/0 :*&(,9,2;# - G*9'.(/76 ,1)4+'6

17. U9,/9013&5 9'(.,*12(%+ ,12A+3+ - "'*1,'+$,/1(+(/46 79'2<,6 - R1<76 9'(.,*12;#6

&*&.5)A.3+ ,1),+(/,E '972<,*

18. U 149,6 .,* *-,8A9#),* /#( .56 *-4:*&56 &.# &*&.0)#.# ,1),+(/,E '972<,*

19. U12A+3&5 .,* L"O

20.@'+(/76 /#( '($(/76 #(&80&'(6 J12#&.51(#/76 R&/0&'(6

1. K(#/;+5&5 ),1;3+ )7&3 /*..#1(/%+ )')C1#+%+ (3 %1'6)

2. "'*1,:*&(,9,2;# (3 %1'6)

3. G*&(,9,2;# &/'9'.(/,E )*46 (3 %1'6)

4. J+'125.(/0 .56 )*Q/06 &E&-#&56 (3 %1'6)

5. L#.#)7.15&5 '1*81,/*..A13+ /#( 9'*/,/*..A13+ - T1,&$(,1(&)46 #()#.,/1;.5 /#(

9'*/,/*..#1(/,E .E-,* (3 %1'6)

6. L#1$(#/0 9'(.,*12;# - L#1$(#/4 &E&.5)# C#.1A<,* (3 %1'6)

7. Z'(.,*12;# .56 #+#-+,06 (3 %1'6)

8. "':1(/0 9'(.,*12;#(3 %1'6)

9. U1),+(/0 1E8)(&5 .56 29*/4D56 (3 %1'6)

10. T1,&$(,1(&)46 '+DE)3+ -'-.(/,E &*&.0)#.,6 859#&.(/%+ (3 %1'6)

11. ?'97.5 /#( #+A9*&5 '-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;#

EFG6BC:9H=>

-NOA[A !ARR6 , J-;/,*1,6 L#8520.1(# ?,1(#/06 G*&(,9,2;#6 – G#1)#/,9,2;#6

!<:H=F9J7=9A 1LNN<677AHA +@HO:>: G*&(,9,2;# .,* R+81%-,* – ?5<#+(&),;

.56 Z'(.,*12;#6 .,* U12#+(&),E 1LNN<ASIA>: Vander A., Sherman J., Luciano D."CG:HFCJ> &@C:>: Broken Hill Publishers Ltd.+JR:> & %<J9:> TCG:B8>: R80+# , 15 7/$./2011ISBN: 9789604892259

Title: PhysiologyAuthor(s): Linda S. CostanzoPublishing Company: Lagos D.Place & Year of Publishing: Athens, 4 th edition/2012ISBN: 9789607875754

EUDOXUS code: 22698807



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

77


K(#97F'(6 /#( &5)'(%&'(6 .,* )#80)#.,6 $(#.;8'+.#( &.5+ (&.,&'9;$#:

https://eclass.duth.gr/eclass/courses/ALEX01130/


+@HO:>: G*&(,9,2;# – J2<'(1;$(, J12#&.51(#/%+ R&/0&'3+

1LNN<ASIA>: R. T#--A +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 2010


T#1#/,9,E85&5 $(#97F'3+ , 59'/.1,+(/0 -9#.:41)# .,* )#80)#.,6 (e-class), -1#/.(/0

'FA&/5&5 &.# -9#;&(# .3+ '12#&.51(#/%+ #&/0&'3+ , ':#1),20 '+$(A)'&3+ -1,4$3+ 2(#

79'2<, .56 2+%&56 /#( ')-7$3&5 .56 E956 , /#8,$52,E)'+5 )'97.5 /#( #+A9*&5

'-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;#.

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 .3+ :,(.5.%+ 2;+'.#( &*+#1.0&'( .3+ '-($4&'%+ .,*6 &.(6 '12#&.51(#/76 –:1,+.(&.51(#/76 #&/0&'(6/#+#:,176 (10%), &.(6 '+$(A)'&'6 -1,4$,*6 (20%) /#( &.(6

.'9(/76 21#-.76 'F'.A&'(6 .,* )#80)#.,6 (70%).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

78

'32 213 2"("+$,/ $$


E’ ) 3 3 4 5


U( &.4<,( .,* )#80)#.,6 ';+#(:

H, )A85)# «@'+'.(/0 VV» (4,* 'F#)0+,*) #-,.'9'; &*+7<'(# .,* )#80)#.,6 «@'+'.(/0 V» -,*

-1,52';.#(. O*+,9(/A , .# )#80)#.# @'+'.(/0 V /#( VV /#9E-.,*+ .5 C#&(/0 E95 .56

'-(&.0)56 .56 @'+'.(/06 /#( #-,&/,-,E+ &., +# )'.#$%&,*+ &.,*6 :,(.5.76 49'6 .(6

7++,('6 .56 /9#&(/06 /#( .56 ),1(#/06 @'+'.(/06.

H, )A85)# «@'+'.(/0 VV» 8'31';.#( 8')'9(%$'6 )A85)# .,* 2+3&.(/,E #+.(/'()7+,* .,*

H)0)#.,6 ?,1(#/06 >(,9,2;#6 /#( @'+'.(/06 , #99A /#( #+#2/#;, 2(# /A8' H)0)# )' 2+3&.(/4

#+.(/';)'+, .(6 C(,9,2(/76 '-(&.0)'6.


.=?<8HFCJ 7I<:>

• OE+$'&5 &' K(-9,'($';6 U12#+(&),E6 (@. G#/06)

• @'+'.(/46 R+#&*+$*#&)46 /#( =A1.'6 OE+$'&56 (@. G#/06)

• @'+'.(/0 R-9,'($%+ J*/#1*3.%+ – OE+$'&5 &.,*6 ?E/5.'6 (@. G#/06)

• ?5<#+(&),; @'+'.(/,E R+#&*+$*#&),E (@. G#/06)

• ?(/1,C(#/0 @'+'.(/0 (@. G#/06)

• R+#&*+$*#&)46 &' >#/.01(# /#( GA2,*6 (@. G#/06)

• >(,9,2(/46 U1(&)46 /#( Z'-.0 K,)0 .,* @,+($;,* (@. G#/06)

• ?'.#8'.A @'+'.(/A O.,(<';# (@. G#/06)• @'+'.(/0 .,* L#1/;+,* (V. ?#1,*9A/,*)

• =#1.,21A:5&5 /#( R9959,E<5&5 @,+($(3)A.3+ (@. G#/06)

• T1,21A))#.# @,+($(3)#.(/06 (@. G#/06)


1. >'9.(&.,-,;5&5 .56 R9*&($3.06 R+.;$1#&56 T,9*)'1A&56-PCR (3 %1'6)

2. T,9*),1:(/,; 2'+'.(/,; $';/.'6 (3 %1'6)

3. =#1.,21A:5&5 DNA )' -'1(,1(&.(/A 7+D*)# (3 %1'6)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

79

0<:9HFBH8<FACI> -BCDB=F>:

R+#9E&'(6 /':#9#;3+ C(C9;,* (book report) 0 A9956 '-(&.5),+(/06 C(C9(,21#:;#6 (3 %1'6).

I -#1#/,9,E85&5 .3+ '12#&.51(#/%+ /#( :1,+.(&.51(#/%+ #&/0&'3+ ';+#( *-,<1'3.(/0 .U( '12#&.51(#/76 /#( :1,+.(&.51(#/76 #&/0&'(6 -1#2)#.,-,(,E+.#( &*+0836 &' .7&&'1#

.)0)#.#.

EFG6BC:9H=>

'A<:LO6C:L $?699A , L#8520.1(# @'+'.(/06

0ACD> 2FA99:QO8> , J-;/,*1,6 L#8525.06 @'+'.(/06 R+81%-,*


+@HO:>: L9#&(/0 /#( ?,1(#/0 @'+'.(/0 1LNN<ASIA>: L3+&.#+.;+,6 H1(#+.#:*99;$56 "CG:HFCJ> &@C:>: R$'9:%+ L*1(#/;$5 +JR:> & %<J9:> TCG:B8>: 2004ISBN: 978-960-343-192-3,?GFCJ> ")E&U&1: 6428

+@HO:>: J(&#2320 &.5 @'+'.(/0 , K^ N/$,&5 1LNN<ASIA>: O.#)A.56 R9#<(%.56 "CG:HFCJ> &@C:>: Z(CA+5 +JR:> & %<J9:> TCG:B8>: 2011ISBN: 978-960-442-024-7,?GFCJ> ")E&U&1: 12469325

+@HO:>: iGenetics - )(# ?'+.'9(/0 T1,&722(&5 1LNN<ASIA>: Peter J. Russell"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 +JR:> & %<J9:> TCG:B8>: 2009

ISBN: 978-960-88412-7-7,?GFCJ> ")E&U&1: 2626


U( -#1#$4&'(6 2;+,+.#( )' .14-, -,* +# '+8#11E+,*+ .5+ '+'120 &*))'.,<0 .3+ :,(.5.%+

&.5 $($#/.(/0 $(#$(/#&;#. O.4<,6 ';+#( );# (&,11,-;# #+A)'&# &., $#&/#9,/'+.1(/4 /#( &.,

)#85.,/'+.1(/4 ),+.79, $($#&/#9;#6.O., -1#/.(/4 &/79,6 .,* )#80)#.,6 , $5 9#$0 &' '12#&.51(#/76 /#( :1,+.(&.51(#/76



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

80

#&/0&'(6 , <15&(),-,(';.#( 5 #+#/#9*-.(/0 )78,$,6. ?'2A95 &5)#&;# $;+'.#( &.5

$5)(,*12;# &/'-.4)'+3+ '-(&.5)4+3+ , 2(’ #*.4 -1,CA99'.#( 5 '-(&.5),+(/0 )78,$,6

$('1'E+5&56 -,* -'1(9#)CA+'( -#1#.015&5 , $(#)41:3&5 *-48'&56 /#( -'(1#)#.(/4

79'2<, .56 *-48'&56.

2OPBBA EFGABCAO@A>

I $($#&/#9;# 2;+'.#( /*1;36 &.# '995+(/A. Y&.4&, &.# -9#;&(# #+#:,1%+ , :1,+.(&.51;3+ ,

0 A993+ '12#&(%+ , #-#(.';.#( #-4 .,*6 :,(.5.76 +# <15&(),-,(0&,*+ F'+4293&&'6 -5276

/#( C(C9(,21#:;#. O*+0836 #*.4 -'1(9#)CA+'( )'97.5 , /#.#+45&5 /#( <10&5

'-(&.5),+(/%+ A1813+ , /':#9#;3+ C(C9;3+ 0 A9956 C(C9(,21#:;#6 &.5+ #229(/0 29%&&#.

'IM:G:F A5F:OJN8B8> - 3AM7:OJN8B8

I #F(,9425&5 2;+'.#( /*1;36 )' 21#-.0 'F7.#&5 &., .79,6 .,* 'F#)0+,* /#( /#.A .(6

'-4)'+'6 'F'.#&.(/76 -'1(4$,*6.

J-(-97,+ , 2;+'.#( #F(,9425&5 .3+ #+#:,1%+ -,* -1,'.,()AD,*+ ,( :,(.5.76 2(# /A8'

'12#&.51(#/0 A&/5&5 .

RF(,9,2,E+.#( ,( 21#-.76 '12#&;'6 /#( ,( -1,:,1(/76 -#1,*&(A&'(6 #*.%+.

H79,6 , '/.()%+.#( 5 '+'125.(/0 &*))'.,<0 &.(6 -#1#$4&'(6 , &.# '12#&.01(# /#( &.(6

*-49,(-'6 $1#&.51(4.5.'6 .,* )#80)#.,6 , /#8%6 /#( 5 (/#+4.5.# &*+$*#&.(/06 &/7B56

/#( #+'FA1.5.56 '12#&;#6 &.# '12#&.01(#.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

81

'32 214 '&#$-,/ 3$&4&2$- $$

"56789: )/" ;<=> .=?<@A> ;<=> -BCDB8> EFGACHFCI> 7:96G=> ECTSE’ ) 3 - 3 4


H, µA85 µ# #-,&/,-'; +# )'.#$%&'( ')-'1(&.#.3)7+5 2+%&5 &<'.(/0 -1,6 ., 8'µ'9(%$'6

-'$;, .56 ?,1(#/06 >(,9,2;#6.


.=?<8HFCJ 7I<:>

H, )A85)# #-,.'9';.#( #-4 10 '+4.5.'6:

J"UHIHR 1: To #22'9(#:41, RNA

J"UHIHR 2: H, µ'.#:,1(/4 RNA

J"UHIHR 3: H, 1(C,&3µ(/4 RNA

J"UHIHR 4: H -13.'Q+,&E+8'&5

J"UHIHR 5: O 2'+'.(/46 /%$(/#6

J"UHIHR 6: T*15+(/46 '+.,-(&)46

J"UHIHR 7: O '+.,-(&)46 .3+ -13.'Q+%+

J"UHIHR 8: U*C(/(.(+;3&5 – T13.'Q+(/0 #-,(/,$4)5&5

J"UHIHR 9: H, 1'-9(/4+(,

J"UHIHR 10: I #+.(21#:0 .,* DNA

EFG6BC?9

E<. -OI58> 2AO698>, J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6


+@HO:>: Genes VIII1LNN<ASIA>: Lewin"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# /#( OVR U.J +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2004ISBN: 960-88412-2-6,?GFCJ> ")E&U&1: 13003327



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

82

+@HO:>: @,+($(%)#.# - &E2<1,+'6 '1'*+5.(/76 -1,&'22;&'(6

1LNN<ASIA>: Brown H. R."CG:HFCJ> &@C:>: BROKEN HILL PUBLISHERS LTD+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010ISBN: 9603998563

,?GFCJ> ")E&U&1: 1 3256614


K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class.

'IM:G:F A5F:OJN8B8> – BAM7:OJN8B8>

T14,$,6 ('+$(Aµ'&5 'F7.#&5 ), JF7.#&5 21#-.0 &., .79,6 .,* 'F#µ0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

83

2&($E$-,/ ",0#-1/ ,-$ ,)++-#$,/ 1/'-+&E&+/1/


E’ ) 4 0 4 5


U( &.4<,( .,* )#80)#.,6 ';+#(:

• "# /#.#+,0&'( , :,(.5.06 C#&(/76 7++,('6 .56 ?,1(#/06 >(,9,2;#6 -,*

&<'.;D,+.#( )' .5 2,+($(#/0 7/:1#&5 .3+ '*/#1*3.%+ /#( +# #+.(95:8'; .,*6

-,9*'-;-'$,*6 /#( &E+8'.,*6 )5<#+(&),E6 1E8)(&56.

• "# #+#-.EF'( (/#+4.5.'6 #+A9*&56 /#( /1(.(/06 &E+8'&56.

• "# #+.(95:8'; 4.( &5)#&;# 7<'( 5 /#.#+45&5 .3+ )5<#+(&)%+ $;+,+.#6 7):#&5

&.# :#(+4)'+# 1E8)(&56 , 8'31%+.#6 0&&,+,6 &5)#&;#6 .5+ #-,&.08(&5 2+%&'3+ /#(

9'-.,)'1'(%+.

• "# )A8'( .(6 C#&(/76 #1<76 .56 1E8)(&56 .56 2,+($(#/06 7/:1#&56 .3+

'*/#1*3.(/%+ ,12#+(&)%+ &.# -9#;&(# .56 $*+#)(/06 ,12A+3&56 .56 $,)06 .,*

2'+'.(/,E *9(/,E.

• "# )A8'( .(6 C#&(/76 #1<76 -,* $(7-,*+ .,*6 µ,1(#/,E6 µ5<#+(&µ,E6 /*..#1(/06

&5 µ#.,$4.5&56.


.=?<8HFCJ 7I<:>

H, )A85)# #-,.'9';.#( #-4 10 '+4.5.'6:

1. I '+'12,-,;5&5 .56 )'.#21#:06 &.,*6 '*/#1*%.'6.

2. U(/,27+'('6 /#( 1E8)(&5 )'.#21#:(/%+ -#1#24+.3+.

3. I 1E8)(&5 .56 $,)06 .56 <13)#.;+56.4. I ),1(#/0 CA&5 .3+ '-(2'+'.(/%+ :#(+,)7+3+.

5. H, )A.(&)# /#( 5 '-'F'12#&;# .,* RNA.

6. H, '+#99#/.(/4 )A.(&)#.

7. U( -13.'\+'6 G /#( ,( -13.'Q+(/76 /(+A&'6 &.5 )'.#2320 &5)A.3+.

8. I 'F'($;/'*&5 .56 $1A&56 .3+ ?AP /(+#&%+.

9. T13.'\+'6 (/1(%)#.#.

10. H# ),+,-A.(# cAMP, JAK-STAT /#( SMAD.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

84

EFG6BC:9H=>

E<. #ASADO 1A9GAOHVJR:LO:>, -9. ,AM8N8HD> ':<FACD> 3F:O:N@A>

E<. -OI58> 2AO698>, "R. ,AM8N8HD> ':<FACD> 3F:O:N@A>


+@HO:>: Genes VIIV 1LNN<ASIA>: Lewin"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2004ISBN: 960-88412-2-6,?GFCJ> ")E&U&1: 13003327

+@HO:>: +: ,QHHA<:: 'FA ':<FACD !<:BINNFB81LNN<ASIA> : Geoffrey M. Cooper & Robert E. Hausman

"CG:HFCJ> &@C:>: -CAG87AYCI> "CGJB=F> $. 'R6BG<A &1$- &." +JR:> & %<J9:> TCG:B8>: -O=5A9G<:QR:O8 , 58 /2011ISBN: 978-960-99895-8-9,?GFCJ> ")E&U&1: 33133232


K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class

'IM:G:F A5F:OJN8B8>- 3AM7:OJN8B8>

T14,$,6 ('+$(Aµ'&5 'F7.#&5 ), 'F7.#&5 21#-.0 &., .79,6 .,* 'F#µ0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

85

ME.&E&$ 1+/ '&#$-,/ 3$&4&2$-


E’ ! 3 6 3 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) "# #+#-.EF,*+ ,( :,(.5.76 $'F(4.5.'6 -'(1#)#.(/,E &<'$(#&),E , $(#.E-3&56 /#(

'972<,* '-(&.5),+(/%+ *-,87&3+ &.5 ?,1(#/0 >(,9,2;# (':#1),20 .56 '-(&.5),+(/06

)'84$,* &.5 ?,1(#/0 >(,9,2;#).

C) "# 'F,(/,(38,E+ ,( :,(.5.76 8'315.(/A /#( -1#/.(/A )' )(# &'(1A C#&(/%+ )'84$3+ /#(

.'<+(/%+ -,* <15&(),-,(,E+.#( &.5 ?,1(#/0 >(,9,2;#.2) "# 'F,(/,(38,E+ ,( :,(.5.76 )' .5+ '1)5+';# /#( .5+ #F(,9425&5 -'(1#)#.(/%+

#-,.'9'&)A.3+.


I '/-#;$'*&5 .3+ :,(.5.%+ '-(.*2<A+'.#( )7&3 .56 &*))'.,<06 .,*6 &' 7+# '1'*+5.(/4

&'+A1(, - -1421#))# (research project): -1#2)#.,-,(,E+ )(# &'(1A -'(1#)A.3+ &.# ,-,;#

<15&(),-,(,E+ )'84$,*6 .56 ),1(#/06 C(,9,2;#6 -1,/'()7+,* +# )'9'.0&,*+ 7+#

&*2/'/1()7+, 2,+;$(, /#( ., -1,Q4+ .,*. U( .'<+(/76 &.(6 ,-,;'6 #&/,E+.#( ,( :,(.5.76 ';+#(:

• M'.#&<5)#.(&)46 &., C#/.01(, A .coli.

• A-,)4+3&5 -9#&)($(#/,E DNA &' )(/10 /9;)#/#

• T,&,.(/,-,;5&5 DNA

• T7B5 )' -'1(,1(&.(/A 7+D*)#

• I9'/.1,:415&5 DNA &' -0/.3)# #2#14D56.

• R-,)4+3&5 RNA & &E+8'&5 cDNA.

•

N/:1#&5 /#( #-,)4+3&5 -13.'Q+%+ &., C#/.01(, A .coli..• PCR & O<'$(#&)46 '//(+5.%+

• ?'.#21#:0 in vitro .

• K5)(,*12;# .,)%+ (/1*,.4),6 , )(/1,.4),6 -#994)'+56 9'-;$#6)

• !C1($,-,;5&5 in situ

• R+,&,Q&.,<5)';#

• ?'97.5 .,* ')C1E,* .,* -,+.(/,E



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

86

EFG6BC:9H=>

-. 2AO698> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6

'. 2<8N:<@:L , R+#-951%.1(# L#8520.1(# ?,1(#/06 – R+#-.*F(#/06 >(,9,2;#6.

#. 1A9GAOHVJR:LO:>, R+#-9513.06 L#8525.06 ?,1(#/06 >(,9,2;#6

2. 1C6XG8> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6


+@HO:>: R+#&*+$*#&)7+, DNA1LNN<ASIA>: Watson D.A. /# "CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.+JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-5-3,?GFCJ> ")E&U&1: 2625.

+@HO:>: J12#&.51(#/,; *-,9,2(&),; &.(6 C(,9,2(/76 '-(&.0)'6

1LNN<ASIA>: Lisa Seidman"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.+JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-9-1,?GFCJ> ")E&U&1: 5319


+@HO:>: M78,$,( &.5 ?,1(#/0 >(,9,2;# - J12#&.51(#/46 U$5246 1LNN<ASIA>: @#9A+56 , @152,1;,* , O#+$#9.D4-,*9,6 & O/AC$56 "CG:HFCJ> &@C:>: K5),/1;.'(, T#+'-(&.0)(, M1A/56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 2014


J+'1246 $('1'*+5.(/0 -1,&'22(&5 )7&3 .56 ':#1),206 '1'*+5.(/,E &'+#1;,* - -1,21A))#.,6

(research project).

2OPBBA GFGABCAO@A>

J995+(/A


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 0 //#( #+#:,176 #-,.'9'&)A.3+ &.,

.79,6 /A8' '12#&.51(#/06 A&/5&56 /#( 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

87

'&#$-,/ -(&1&3$&4&2$-


E’ ! 3 3 4 5


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) +# #-,/.0&,*+ ,( :,(.5.76 2+%&'(6 2(# .5 $,)0 /#( ,12A+3&5 .,* #+,&,-,(5.(/,E

&*&.0)#.,6

C) +# /#.#+,0&,*+ .(6 C#&(/76 #1<76 9'(.,*12;#6 .,* #+,&,-,(5.(/,E &*&.0)#.,6

2) +# )'9'.0&,*+ .,*6 -,9E-9,/,*6 )5<#+(&),E6 -,* $(7-,*+ .(6 #+,&,9,2(/76

#-,/1;&'(6


.=?<8HFCJ 7I<:>

• J-(&/4-5&5 .,* #+,&,-,(5.(/,E &*&.0)#.,6 ((&.,1(/0 #+#&/4-5&5 ,

7):*.5 /:*&(/0 #+,&;# , -1,&#1),&.(/0 /'($(/0 /'-;/.5.5 #+,&;#) .

• LE..#1# /#( U12#+# .,* #+,&,-,(5.(/,E &*&.0)#.,6.

• N):*.5 /:*&(/0 #+,&;# /#( T1,&#1),&.(/0 / '($(/0 /'-;/.5.5 #+,&;#: #1<76 ,

)5<#+(&),; #+#2+%1(&56 /#( $1A&56.

• R+.(24+# – '-;.,-,( – #+,&,2,+(/4.5.# /#( #+.(2,+(/4.5.# – #-.7+(# - *-,$,<';6

#+#2+%1(&56 -1,.E-,*.

• R+.(&%)#.#. >#&(/0 $,)0 , 9'-.0 $,)0 #+,&,&:#(1(+%+. HAF'(6 #+.(&3)A.3+ /#(

C(,9,2(/76 9'(.,*12;'6. K1#&.(/76 9'(.,*12;'6 )'&,9#C,E)'+'6 #-4 #+.;&3)#.

UB3+(&)46 – JF,*$'.713&5 . T,9*/93+(/A /#( ),+,/93+(/A #+.(&%)#.#. !-,$,<7#6 > /#(

H 9'):,/*..A13+.

• U12A+3&5 /#( 7/:1#&5 .3+ #+,&,&:#(1(+(/%+ 2,+($;3+. T,9*2,+($(#/0 ,12A+3&5 .3+ #+,&,&:#(1(+(/%+ 2,+($;3+. T#1#2320 .56 -,(/(9,),1:;#6 .3+ #+.(&3)A.3+ -

?5<#+(&),; '.'1,27+'(#6. R99#20 (&,.E-,* – )'.A-.3&5 .AF56. N/:1#&5 .3+

#+,&,&:#(1(+(/%+ 2,+($;3+ – 1E8)(&5 .56 )'.#21#:06. @,+;$(# #+.(&3)A.3+ /#(

)5<#+(/0 .

• R9959'-($1A&'(6 #+.(24+,* – #+.(&%)#.,6. R1<76 /#( ':#1),276.

• ?';D,+ &E)-9'2)# (&.,&*)C#.4.5.#6. @'+(/0 ,12A+3&5 /#( /951,+4)5&5 .3+

),1;3+ MHC. ?41(# /#( 2,+;$(# MHC. T,9*),1:(&)46. L*..#1(/0 /#.#+,)0 . MHC /#(

(/#+4.5.# #+,&,9,2(/06 #-4/1(&56. MHC /#( '*#(&85&;# &' #&87+'('6.• J-'F'12#&;# /#( -#1,*&;#&5 .,* #+.(24+,*. J#*.46-MHC -'1(,1(&)46 .3+ H



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

88

9'):,/*..A13+. U 149,6 .3+ #+.(2,+,-#1,*&(#&.(/%+ /*..A13+. L*..#1,-9#&)#.(/0

,$46 '-'F'12#&;#6 /#( -#1,*&;#&56 .,* #+.(24+,* – '+$,2'+0 #+.(24+#. J+$,/*..#1(/0

,$46 '-'F'12#&;#6 /#( -#1,*&;#&56 #+.(24+,* – 'F32'+0 #+.(24+#. T#1,*&;#&5 )5

-'-.($(/%+ #+.(24+3+.

• !-,$,<7#6 .3+ H 9'):,/*..A13+. K,)0 /#( 149,6 .3+ #C /#( 2$ H /*..#1(/%+ *-,$,<73+. U12A+3&5 /#( #+#$(A.#F5 .3+ 2,+($;3+ .,* *-,$,<7# .3+ H 9'):,/*..A13+.

OE)-9'2)# .,* H /*..#1(/,E *-,$,<7#: TCR-CD3. J-(/,*1(/A )')C1#+(/A )41(# .3+ H

/*..A13+. R99,$1#&.(/4.5.# .3+ H /*..A13+.

• Y1;)#+&5 , '+'12,-,;5&5 /#( $(#:,1,-,;5&5 .3+ H /*..A13+. Y1;)#+&5 .3+ H

/*..A13+ &., 8E), #$7+# – M*)(/0 '-(9,20 : 8'.(/0 /#( #1+5.(/0 '-(9,20 – J+'12,-,;5&5

.3+ C,585.(/%+ H /*..A13+ – K(#:,1,-,;5&5 .3+ H /*..A13+ – L*..#1(/46 8A+#.,6 –

T'1(:'1(/A 2$ H /E..#1#. R+,&,9,2(/0 #+,<0 .

• T#1#2320 , '+'12,-,;5&5 /#( $(#:,1,-,;5&5 .3+ > /*..A13+. Y1;)#+&5 .3+ > /*..A13+ – J+'12,-,;5&5 /#( -,99#-9#&(#&)46 – =*)(/0 #-4/1(&5 - >9#&.(/A /7+.1#

/#( #+.(2,+,'-#24)'+5 '+'12,-,;5&5 .3+ > /*..A13+

• L*..#1,/;+'6. V$(4.5.'6 /*..#1,/(+%+ – !-,$,<';6 /*..#1,/(+%+ – T#1#2320

/*..#1,/(+%+ #-4 .,*6 *-,-958*&),E6 Th1 /#( Th2. ",&0)#.# -,* &<'.;D,+.#( )'

/*..#1,/;+'6. M'1#-'*.(/76 <10&'(6 .3+ /*..#1,/(+%+ /#( .3+ *-,$,<73+ .,*6.

• H, &E&.5)# .,* &*)-951%)#.,6. Z'(.,*12;'6 – &*&.#.(/A – '+'12,-,;5&5 .,*

&*)-951%)#.,6. PE8)(&5 .,* &*&.0)#.,6 .,* &*)-951%)#.,6. >(,9,2(/76 &*+7-'('6

.56 '+'12,-,;5&56 .,* &*)-951%)#.,6.

• L*..#1,)'&,9#C5.(/0 #+,&;#. K1#&.(/A /E..#1# /#( #-,/1;&'(6. @'+(/76

($(4.5.'6 .3+ $1#&.(/%+ /*..A13+. L*..#1,.,F(/A H /E..#1#. G*&(/A :,+(/A ("L )

/E..#1#. JF#1.%)'+5 #-4 #+.(&%)#.# /*..#1,)'&,9#C5.(/0 /*..#1,.,F(/4.5.#.

?'.#+A&.'*&5 9'*/,/*..A13+. L*/9,:,1;# 9'):,/*..A13+ - )41(# /*..#1(/06

-1,&/4995&56.

• G9'2),+0 /#( :9'2),+%$56 #-4/1(&5 - #+.(:9'2),+%$'(6 -#1A2,+.'6.

• I #+,&,9,2(/0 #-4/1(&5 &.(6 9,()%F'(6. V,2'+';6 9,()%F'(6 , C#/.51(#/76

9,()%F'(6 , 9,()%F'(6 #-4 -13.4D3# /#( 79)(+8'6.

• T13.,2'+';6 /#( $'*.'1,2'+';6 #+,&,9,2(/76 #-,/1;&'(6. ?+0)5 H /#( >

9'):,/*..A13+.

• J)C49(#.


1. ?,1:,9,2(/0 'F7.#&5 /#( .#*.,-,;5&5 /*..A13+ #;)#.,6 - '-;<1(&)# - <1%&'(6 (3

%1'6).

2. R-,)4+3&5 9'):,/*..A13+ - K(#<31(&)46 9'):,/*..A13+ -'1(:'1(/,E #;)#.,6 &'

:(/495 /#( )7.15&5 /*..A13+ ( +'/1%+/D3+.#+%+) - /#99(712'(# 9'):,/*..A13+ /#(



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

89

*-,9,2(&)46 C(3&()4.5.#6 (3 %1'6).

3. K,/()#&;# #(),&*2/4995&56 (hemagglutination assay) (3 %1'6).

4. R+,&,$,/()#&;# ELISA (#+,&,-1,&1,:5.(/0 #+A9*&5 &.'1'A6 :A&56 )' &E+$'&5 '+DE),*

(6 %1'6).5. R+,&,$,/()#&;# #+,&,:8,1(&),E 2(# .5+ .#*.,-,;5&5 '($(/%+ #+.(&3)A.3+ (5 %1'6).

6. >#&(/76 #1<76 /*..#1,)'.1;#6 1,06 – #+,&,:#(+4.*-,6 9'):,/*..A13+ )'

/*..#1,)'.15.0 1,06 (2 %1'6).

7. R+,&,-,;5&5 . T1,&$(,1(&)46 /#( .#*.,-,;5&5 -'-.($(/%+ '-(.4-3+ 2(# '-(9'2)7+#

#+.(24+# - CA&'(6 $'$,)7+3+ (3 %1'6).

8. M'315.(/4 '12#&.01(,: #+A9*&5 #-,.'9'&)A.3+ – &E2<1,+'6 .'<+(/76 R+,&,C(,9,2;#6

(3 %1'6).EFG6BC:9H=>

-FCAH=<@98 %O@KOFA , J-;/,*1,6 L#8520.1(# ?,1(#/06 R+,&,C(,9,2;#6.


H;.9,6: R"UOUZU@VR , 25 7/$,&5 O*221#:7#6: Goldsby R, Kindt T, Osborne B,

Kuby J

J/$,.(/46 U;/,6: V#.1(/76 J/$4&'(6 T. =.T#&<#9;$5

H4-,6 & =14+,6 N/$,&56: 2012ISBN: 978-9963-716-14-2L3$(/46 J!KU]UO: 23076003

H;.9,6: LZV"VLI R"UOU>VUZU@VR: ., #+,&,-,(5.(/4 &E&.5)# &.5+ *2';# /#( .5 +4&,

O*221#:7#6: Janeway - TraversJ/$,.(/46 U;/,6: V#.1(/76 J/$4&'(6 T. =.

T#&<#9;$5 H4-,6 & =14+,6 N/$,&56: 2002


+@HO:>: O5)'(%&'(6 $(#97F'3+ ?,1(#/06 R+,&,C(,9,2;#6 V

1LNN<ASIA>: J-(/. L#8. R(/#.'1;+5 =9;<9(# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2012



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

90


+@HO:>: ?UPVRLI R"UOU>VUZU@VR - J2<'(1;$(,

J12#&.51(#/%+ R&/0&'3+ 1LNN<ASIA>: J-(/. L#8. R(/#.'1;+5 =9;<9(# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010


K(#97F'(6 &., #):(87#.1, , C;+.', , /1(.(/0 &*D0.5&5 )' $(A9,2, /#( &*))'.,<0 .3+

:,(.5.%+ , $(#97F'(6 &' '($(/A 87)#.# #-4 -1,&/'/95)7+,*6 ,)(95.76 , 59'/.1,+(/0

-9#.:41)# .,* )#80)#.,6 (e-class), -1#/.(/0 'FA&/5&5 &.# -9#;&(# .3+ '12#&.51(#/%+

#&/0&'3+.

2OPBBA EFGABCAO@A>

J995+(/0


U( :,(.5.76 #F(,9,2,E+.#( )' CA&5 .5+ '-;$,&0 .,*6 &.(6 '12#&.51(#/76 #&/0&'(6 .,*

)#80)#.,6 (.7&.) /#( .(6 .'9(/76 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

91

2"("+$,/ !4/.)1'*( ,-$ "U"4$U/


J’ ! 3 3 4 5


O.4<,( .,* )#80)#.,6 ';+#(:

• I '(&#2320 .3+ C#&(/%+ '++,(%+ .56 @'+'.(/06 T958*&)%+.

• I 'F,(/';3&5 .3+ :,(.5.%+ µ' .(6 C#&(/76 #1<76 .,* /#8,1(&µ,E .56 2'+'.(/06

-,(/(94.5.#6.

• I /#.#+45&5 /#( ':#1),20 C#&(/%+ )'84$3+ -,&,.(/,-,;5&56 /#( #+A9*&56 .56

2'+'.(/06 -,(/(94.5.#6.

• I /#.#+45&5 .3+ 'F'9(/.(/%+ $*+A)'3+ $(#)41:3&56 .56 2'+'.(/06 -,(/(94.5.#6

&' ),1(#/4 '-;-'$, #99A /#( &' '-;-'$, -958*&)%+.

• I -#1,*&;#&5 /#( /#.#+45&5 .3+ $*+A)'3+ /#8,1(&µ,E .56 'F79(F56 .3+ '($%+.

• I 'F,(/';3&5 µ' .5+ #+#9*.(/0 )'8,$,9,2;# )'97.56 .56 'F79(F56 /#( .3+

&*&<'.;&'3+ .3+ '($%+.


M'315.(/4 )71,6

• I -1,79'*&5 /#( '-;$1#&5 .56 'F'9(/.(/06 &/7B56.

• T,(/(94.5.# (M'%15 µ# Hardy-Weinberg, -,(/(94.5.# &' -,&,.(/,E6 /#( -,(,.(/,E6

<#1#/.01'6 , -,(/(94.5.# &' 2'+'.(/4 /#( :#(+,.*-(/4 '-;-'$,).

• T958*&)(#/0 $,)0 (oµ,µ(F;# , 2'+'.(/0 -#17/9(&5 , 5 #1<0 .,* ($1*.0 , $1#&.(/4

)72'8,6 -958*&),E , )'.A99#F5 , 2,+($(#/0 1,0 , 8'31;'6 'F79(F56).

• G*&(/0 J-(9,20 .• J($,27+'&5 (.E-,( '($,27+'&56: #99,-A.1(# , &*µ-A.1(# , -#1#-A.1(# , 2'+'.(/76

8'31;'6 2#( .5+ '($,27+'&5 , #-#(.,Eµ'+,6 <14+,6 2(# .5+ '($,27+'&5 ).

• T1,&#1µ,20 (#+#2+%1(&5 .56 -1,&#1µ,206 , '-;-'$# '-(9,206).

• I )'97.5 .56 (&.,1;#6 .56 'F79(F56 (.#F(+4µ5&5 , :*9,27+'&5 µ' CA&5 ),1:,9,2(/A

/#( µ,1(#/A $'$,)7+# , µ,1(#/4 1,94().

• >(,2'321#:;# (2'321#:(/A -14.*-# , >(/#1(#+(&µ46-K(#&-,1A).

• JF79(F5 &., µ,1(#/4 '-;-'$, (1*8)46 'F79(F56 #9959,*<(%+ , 'F79(F5

$(-9#&(#&)7+3+ 2,+($;3+ , )'.#8'.A &.,(<';# , 'F79(F5 )'278,*6 2,+($(%µ#.,6 ,



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

92

'F79(F5 -,9*2,+($(#/%+ ,(/,2'+'(%+ , 'F79(F5 2,+($;3+ /#( -13.'Q+%+ , ,1(D4+.(#

2,+($(#/0 )'.#:,1A).

J12#&.51(#/76 R&/0&'(6

1. H, 2,+($;3)# /#( CA&'(6 $'$,)7+3+ (3 %1'6)

2. J(&#2320 &.5 <10&5 9,2(&)(/,E 2(# .5+ #+A9*&5 -,9*µ,1:(&µ%+ '+46 +,*/9',.($;,* /#( .,+ *-,9,2(&)4 .56 #+(&,11,-;#6 &E+$'&56 (3 %1'6)

3. G1,+.(&.51(#/76 #&/0&'(6 (3 %1'6)

EFG6BC:LBA

!=<FBHI<A !6BK:L , J-;/,*15 L#8520.1(# @'+'.(/06 T958*&)%+


+@HO:>: JF'9(/.(/0 >(,9,2;#

1LNN<ASIA>: Douglas J. Futyuma"CG:HFCJ> &@C:>: ITE - TR"JTVOHI?VRLJO JLKUOJVO LPIHIO.+JR:> & %<J9:> TCG:B8>: I1A/9'(, , 1995ISBN: 960-7309-20-0,?GFCJ> ")E&U&1: 345

+@HO:>: JF79(F5 1LNN<AS=@>: Barton " , Briggs D, Eisen J, Goldstein D, Patel N"CG:HFCJ> &@C:>: UTOPIA JLKUOJVO JTJ +JR:> & %<J9:> TCG:B8>: R80+# , 2011ISBN: 978-960-99280-4-5

,?GFCJ> ")E&U&1: 12465721


U( &5)'(%&'(6 .,* )#80)#.,6 ';+#( $(#87&()'6 &., $(#$;/.*, )7&3 .56 -9#.:41)#6 e-class.


H# :*99A$(# .3+ '12#&.51(#/%+ /#( :1,+.(&.51(#/%+ #&/0&'3+ .,* )#80)#.,6 ';+#(

$(#87&()# &., $(#$;/.*, )7&3 .56 -9#.:41)#6 e-class.


K(#97F'(6 , '12#&.51(#/76 #&/0&'(6 , :1,+.(&.01(#.

2OPBBA EFGABCAO@A>

J995+(/A.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

93

3$&!4/#&0&#$,/


"’ ) 4 3 5 5


>(,-951,:,1(/0 : CA&'(6 , #9241(8µ,( /#( '12#9';#.


.=?<8HFCJ 7I<:>

J:#1µ,276 *-,9,2(&.%+ &.5 C(,9,2;# , ,1(&µ,; - I >(,-951,:,1(/0 36 '12#9';, /#(

'1'*+5.(/4 -'$;, - R9241(8µ,( , -1,21Aµµ#.# , 5 &5 µ#&;# .,* $(#$(/.E,* (client-server model) ->A&'(6 $'$,µ7+3+: K,µ0 /#( #+#D0.5&5 -951,:,1(%+ , ,( -97,+ 2+3&.76 CA&'(6 $'$,µ7+3+ -

O.,;<(&5 $E, #9959,*<(%+: O<,9#&.(/,; #9241(8µ,( : Needleman & Wunsch, Smith & Waterman -

T;+#/'6 C#8µ,9425&56 (PAM, BLOSUM) - O.,;<(&5 $E,

#9959,*<(%+: J*1'&.(/,; #9241(8µ,( : ,( #9241(8µ,( -,* <15&(µ,-,(,E+.#( &.# -1,21Aµµ#.#

BLAST /#( FAST - O.,;<(&5 -,99%+ #9959,*<(%+: T1,C90 µ#.# , #9241(8µ,( /#( '*1736

<15&(µ,-,(,Eµ'+# -1,21Aµµ#.# - G*9,2'+'.(/A $7+$1#. U1(&µ,; , µ,1:76 $7+$13+ ,

R9241(8µ,( 2(# .5+ $5 µ(,*12;# $7+$13+ µ7&3 &.,(<;&'3+ #9959,*<(%+ - T13.'Q+(/A µ,.;C# :

-1,&$(,1(&µ46 , #+#D0.5&5 , CA&'(6 $'$,µ7+3+ /#( '12#9';# #+#D0.5&56 – T14C9'B5

#+,(/.%+ -9#(&;3+ #+A2+3&56 – T14C9'B5 µ'.#21#:(/%+ 1*8µ(&.(/%+ &.,(<';3+ - Expressed

Sequence Tags: ($(#(.'14.5.'6 /#( -1,C90 µ#.# - Z'(.,*12(/0 2'+,µ(/0 /#( 2,+($(#/0 7/:1#&5 :

microarrays. T1,C90 µ#.# , #9241(8µ,( , -1,21Aµµ#.# - J:#1µ,276 &.5 K,µ(/0 >(,9,2;#:

-14C9'B5 $'*.'1,.#2,E6 $,µ06 -13.'Q+%+ /#( RNA, -14C9'B5 $(#µ'µC1#+(/%+ .µ5 µA.3+ ,

homology modeling, #+#2+%1(&5 µ,.;C,* #+#$;-93&56 , ab initio -14C9'B5 -13.'Q+(/06 $,µ06.


JP@ROVR 15 , 5 YPJO:

"N1'*+# /#( <10&5 (µ7&3 .,* $(#$(/.E,*) .3+ CA&'3+ $'$,µ7+3+ /#( .3+ ':#1µ,2%+ .,*6

µ' &/,-4 .5+ .#*.,-,;5&5 /#( <#1#/.51(&µ4 µ(#6 -13.'\+56 µ' CA&5 '99'(-0 /#(

#-,&-#&µ#.(/A &.,(<';#."


" =10&5 &.,(<;&'3+ , 'F'9(/.(/%+ &<7&'3+ /#( µ,.;C3+ 2(# .5+ .#*.,-,;5&5 &*+.515 µ7+3+

-13.'Q+(/%+ -'1(,<%+ , /#( ., &<'$(#&µ4 µ'.#99AF'3+ &' #*.76 .(6 -'1(,<76 µ' &.4<, .5

$5 µ(,*12;# $,µ(/%+ 0 //#( 9'(.,*12(/%+ #99#2%+"




!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

94

"J:#1µ,276 &.5 $,µ(/0 C(,9,2;#: O<7&'(6 #9959,*<;#6-$,µ06- 9'(.,*12;#6 -13.'Q+%+ /#(

&<'$(#&µ46 µ' *-,9,2(&.(/76 µ'84$,*6 µ'.#99AF'3+ /#.A99593+ 2(# ., <#1#/.51(&µ4

#*.%+ .3+ &<7&'3+"

EFG6BC?9 (FCJOA:> '. 2OLCJ> , J-;/,*1,6 L#8525.06 (!-,9,2(&.(/0 /#( K,)(/0 >(,9,2;#).


+@HO:>: >(,-951,:,1(/0 1LNN<ASIA>: BAXEVANIS & OVELLETTE+JR:> & %<J9:> TCG:B8>: 15 7/$./2004ISBN: 978-960-394-222-1,?GFCJ> ")E&U&1: 41233

+@HO:>: J(&#2320 &.,*6 #9241(8),*6 >(,-951,:,1(/06 1LNN<ASIA>: NEIL C. JONES, PAVEL A. PEVZNER+JR:> & %<J9:> TCG:B8>: 15 /2010ISBN: 978-960-461-388-5,?GFCJ> ")E&U&1: 21522

+@HO:>: >(,-951,:,1(/0 1LNN<ASIA>: O,:;# L,&&($A +JR:> & %<J9:> TCG:B8>: 15 /2009

ISBN: 978-960-9309-60-8,?GFCJ> ")E&U&1: 5110


KVRZJ]JVO , HPJVO !TU=PJYHVLJO JP@ROVJO


JP@ROVJO 30%, J]JHROJVO (multiple choice) 70%



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

95

"'3#)&4&2$- & '&#$-,/ 3$&4&2$- -(-!+)U/1


"’ ) 4 0 3 4


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) "# #-,/.0&,*+ ,( :,(.5.76 C#&(/76 2+%&'(6 .56 J)C1*,9,2;#6 .3+ #&-,+$E93+ /#( .3+

&-,+$*9,D%3+ )7&3 .56 )'97.56 .56 ')C1*,27+'&56 -14.*-3+ ,12#+(&)%+ (model

organisms - C. elegans , D. melanogaster , Xenopus laevis , Zebrafish, X1+(8# , T,+.(/46).

C) "# )'9'.0&,*+ ,( :,(.5.76 .,*6 C#&(/,E6 ),1(#/,E6 )5<#+(&),E6 -,* $(7-,*+ .5+

#+A-.*F5 .3+ -1,.E-3+ ,12#+(&)%+ /#(

2) "# $(#-(&.%&,*+ ,( :,(.5.'6 4.( ,( ),1(#/,; )5<#+(&),; -,* '+7<,+.#( &.5+ R+A-.*F5

7<,*+ &*+.5158'; /#.A .5+ JF79(F5 .


• M')'9(%$'(6 7++,('6 &.5 >(,9,2;# R+A-.*F56.

• U( C#&(/76 .'<+(/76 2(# .5 )'97.5 .56 R+A-.*F56.

• T14.*-,( U12#+(&),;.

• J)C1*,9,2;# .,* C. elegans.O<'$(#&)46 .,* -1,.E-,* .,* &%)#.,6 .3+ #&-,+$E93+ /#( ),1(#/,; )5<#+(&),; V:

C. elegans .

• J)C1*,9,2;# .56 D. melanogaster

O<'$(#&)46 .,* -1,.E-,* .,* &%)#.,6 .3+ #&-,+$E93+ /#( ),1(#/,; )5<#+(&),; VV:

D. melanogaster .

• J)C1*,9,2;# .,* X. laevis

O<'$(#&)46 .,* -1,.E-,* .,* &%)#.,6 .3+ &-,+$*9,D%3+ /#( ),1(#/,;

)5<#+(&),; V:

X. laevis .

• E)C1*,9,2;# .56 41+(8#6

O<'$(#&)46 .,* -1,.E-,* .,* &%)#.,6 .3+ &-,+$*9,D%3+ /#( ),1(#/,;

)5<#+(&),; VV:

X1+(8#.

• J)C1*,9,2;# .,* -,+.(/,E

O<'$(#&)46 .,* -1,.E-,* .,* &%)#.,6 .3+ &-,+$*9,D%3+ /#( ),1(#/,;

)5<#+(&),; VVV: T,+.(/46 – a+813-,6.

• >#&(/A <#1#/.51(&.(/A .56 U12#+,27+'&56.• R+A-.*F5 .3+ &3)(.%+ /#( .3+ -#1#2%23+ .,*6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

96

• R+A-.*F5 .3+ A/13+.

• R+A-.*F5 .56 /#1$(A6 , .3+ +':1%+ /#( .3+ 2,+A$3+.

• JF79(F5 /#( #+#-.*F(#/,; )5<#+(&),; (Evo-Devo)

EFG6BC:9H=>

'. 2<8N:<@:L , R+#-951%.1(# L#8520.1(# ?,1(#/06 >(,9,2;#6 – R+#-.*F(#/06 >(,9,2;#6.

2. 1C6XG8> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6.


+@HO:>: >#&(/76 R1<76 >(,9,2;#6 R+A-.*F56 , 25 N/$,&5

1LNN<ASIA>: JMW Slack

"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2007 –ISBN: 960-88412-3-2,?GFCJ> ")E&U&1: 26242.


O( &5)'(%&'(6 .,* )#80)#.,6 ';+#( $(#87&()'6 )7&3 .56 -9#.:41)#6 e-class.

+@HO:>: I R+#-.*F(#/0 >(,9,2;# .56 D.melanogaster

1LNN<ASIA>: @. O/AC$56 – ?. @152,1;,* +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2005 –

+@HO:>: I -1%()5 #+A-.*F5 .,* +5)#.%$,*6 C. elegans

1LNN<ASIA>: ?. @152,1;,*- @. O/AC$56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2005 –

+@HO:>: J)C1*,9,2;# /#( ?,1(#/0 >(,9,2;# R+A-.*F56-T#1,*&(A&'(6 )#80)#.,6

1LNN<ASIA>: ?. @152,1;,*- @. O/AC$56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2012



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

97


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &.,

)A85)# <15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, ,

:,(.5.06 #-,/.A 2+%&'(6 , #99A #+#-.E&&'( / #( (/#+4.5.'6 -,* .,* '-(.17-,*+ +# &<'$(AD'( -'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&,

/#( )' ., $($A&/,+.#.

2OPBBA GFGABCAO@A>

J995+(/A , &' ,1(&)7+'6 -'1(-.%&'(6 <15&(),-,(';.#( #229(/0 C(C9(,21#:;#.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 /A8' '12#&.51(#/06 A&/5&'(6

/#( &' 21#-.76 'F'.A&'(6 &., )A85)# /#( &., '12#&.01(, &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

98

"0-#'&1'"(/ 3$&+"%(&4&2$-


1+’ ) 3 2 4 4


U &.4<,6 .,* )#80)#.,6 ';+#(:

I /#.#+45&5 #-4 .,*6 :,(.5.76 .3+ C#&(/%+ #1<%+ -,* $(7-,*+ .5+ '-(&.0)5 .56

C(,.'<+,9,2;#6 , 4-36 #*.0 7<'( 'F'9(<8'; )7&# #-4 #(%+'6. Y6 .'<+,9,2;#6 #(<)06 , 5

C(,.'<+,9,2;# &0)'1# ')-97/'.#( &<'$4+ &' 49'6 .(6 $(#$(/#&;'6 -#1#23206

C'9.(3)7+3+ C(,-1,Q4+.3+ /#( -#1,<06 C'9.(3)7+3+ *-51'&(%+ &' 87)#.# *2';#6 ,

-#1#23206 .1,:;)3+ , -1,&.#&;#6 -'1(CA99,+.,6 /#( 2'312;#6. O*+$*AD,+.#6 2+%&'(6

-#1#$,&(#/06 /#( &E2<1,+56 '+D*)(/06 /#( )(/1,C(#/06 C(,.'<+,9,2;#6 /#( $;+,+.#6

($(#;.'15 &5)#&;# &.5+ .'<+,9,2;# , .(6 -1,,-.(/76 /#( .(6 ':#1),276 .3+ '+DE)3+ /#(

.3+ )(/1,,12#+(&)%+ , ., )A85)# &<'$(A&.5/' 7.&( %&.' +# /#9E-.'( .(6 #+A2/'6 .3+

:,(.5.%+ 2(# '+46 '*1E.'1,* :A&)#.,6 2+%&'3+.


.=?<8HFCJ 7I<:>

• J(&#2320 &.5+ J+D*)(/0 /#( ?(/1,C(#/0 >(,.'<+,9,2;#.

• H'<+,9,2;# L#8#1(&),E J+DE)3+: L#.(,E&# J-'F'12#&;# (Down Stream Processing),

=13)#.,21#:(/76 H'<+(/76 ( =13)#.,21#:;# K(#-'1#.4.5.#6 , =13)#.,21#:;#

V,+.,#+#99#206 , =13)#.,21#:;# O*22'+;#6), L9()A/3&5 !2106 =13)#.,21#:;#6 O.0956

(Scale-up), ?,1:,-,;5&5 T1,Q4+.,6.

• J+D*)(/0 L(+5.(/0 : L(+5.(/76 JF(&%&'(6 , R+#,.,90 J+D*)(/06 R+.;$1#&56 , J-;$1#&5 .56

M'1),/1#&;#6 /#( .,* pH &.(6 J+D*)(/76 R+.($1A&'(6.

• R/(+5.,-,(5)7+,( >(,/#.#9E.'6: H'<+(/76 R/(+5.,-,;5&56 J+DE)3+ , H'<+(/76

R/(+5.,-,;5&56 L*..A13+ , T9',+'/.0)#.# R/(+5.,-,;5&56 , T1,b-,87&'(6 G,173+

R/(+5.,-,;5&56 , J-;$1#&5 .56 R/(+5.,-,;5&56 &.# ?,1(#/A /#( L(+5.(/A =#1#/.51(&.(/A

.,* J+DE),* , J-;$1#&5 .56 R/(+5.,-,;5&56 &., LE..#1,.

• >(,#+.($1#&.01'6: HE-,( >(,#+.($1#&.013+ (>(,#+.($1#&.01#6 K(#9';-,+.,6 N12,*

T901,*6 R+#);F'36 , >(,#+.($1#&.01#6 O*+'<,E6 Z'(.,*12;#6 T901,*6 R+#);F'36 ,

>(,#+.($1#&.01#6 O.0956 , >(,#+.($1#&.01#6 P'*&.,-,(5)7+56 L9;+56), L(+5.(/0

>(,#+.($1#&.013+ , O*&.0)#.# R'1(&),E , H, T14C95)# .,* R:1(&),E , ?78,$,(

R-,&.';13&56.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

99

• J:#1),276 .56 >(,.'<+,9,2;#6 &.5+ >(,)5<#+;# H1,:;)3+: U(+,-,(;# , W*8,-,(;# ,

R1.,-,(;# , H*1,/,);# , T#1#2320 >1%&()3+ J9#;3+ , T#1#&/'*0 T1,Q4+.3+ G1,E.3+.

• R-,(/,$4)5&5 R21,.,C(,)5<#+(/%+ R-,C90.3+ 2(# T#1#2320 T1,Q4+.3+ !B5906

T1,&.(87)'+56 RF;#6: T#1#2320 T4&()56 /#( J+'12'(#/06 R(8#+4956 #-4

R21,.,C(,)5<#+(/A R-4C95.# , J+D*)(/0 !$149*&5 R)E9,* , J+D*)(/0 !$149*&5 L*..#1(+,E<3+ T1%.3+ !9%+ , J/)'.A99'*&5 H*1,2A9#/.,6 , T#1#2320 W3,.1,:%+.

• J:#1),276 .56 >(,.'<+,9,2;#6 &.5+ T#1#2320 T13.'Q+(/%+ T#1#&/'*#&)A.3+:

T#1#2320 ?,+,/*..#1(/06 T13.'\+56 , T#1#2320 R)(+,F73+.

• >(,9,2(/46 L#8#1(&)46: R'14C(# /#( R+#'14C(# =%+'*&5 .

• J:#1),276 .56 >(,.'<+,9,2;#6 &.5+ =#1.,-,(;# , !:#+.,*12;# /#( >*1&,$'B;#.

• J:#1),276 .56 >(,.'<+,9,2;#6 &.5+ OE+8'&5 U9(2,&#/<#1(.%+ /#( O#/<#1,-J+%&'3+.

• R+#9*.(/76 J:#1),276: >(,#(&85.01'6 , J.'1,2'+06 /#( U),(,2'+06 ELISA.

• M'1#-'*.(/76 J:#1),276: @'+'.(/76 R+3)#9;'6 , M'1#-';# "',-9#&(%+ , T1,C90)#.#

L*/9,:,1(#/,E O*&.0)#.,6.

• G#1)#/'*.(/76 J:#1),276: T#1#2320 R+.(C(,.(/%+ , T#1#2320 V+&,*9;+56.

• J(&#2320 &.# O*&.0)#.# K(#<';1(&56 T,(4.5.#6 /#( &.# O*&.0)#.# K(#<';1(&56

R&:A9'(#6 H1,:;)3+ (HAACP) &.5+ >(,)5<#+;#.


1. T#1#2320 ),+,/*..#1(/06 -13.'\+56: R'14C(# -#1#2320 D*)%+ (2h).

2. R/(+5.,-,;5&5 D*)%+ &' :*&(/A *-,&.1%)#.# (2h).

3. H'<+,9,2;# D*)%&'3+ )' #/(+5.,-,(5)7+'6 DE)'6 (2h).

4. J-(&/7B'(6 &' C(,)5<#+(/76 ),+A$'6 (3h).

EFG6BC?9

$. ,:L<C:LH6> , J-;/,*1,6 L#8525.06 J:#1),&)7+56 >(,.'<+,9,2;#6.


+@HO:>: J+D*)(/0 >(,.'<+,9,2;# 1LNN<ASIA>: V. L9%+56 "CG:HFCJ> &@C:>: T#+'-(&.5)(#/76 J/$4&'(6 L10.56 +JR:> & %<J9:> TCG:B8>: L10.5 , 1997ISBN: 978-960-524-304-3,?GFCJ> ")E&U&1: 356



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

100

+@HO:>: >(,.'<+,9,2;# H1,:;)3+ 1LNN<ASIA>: H. P,E/#6 "CG:HFCJ> &@C:>: O. @(#<,E$56 & OIA O.E.+JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 2009ISBN: 978-960-6700-30-9,?GFCJ> ")E&U&1: 8921

+@HO:>: >(,.'<+,9,2;# )' &.,(<';# C(,<5)(/06 )5<#+(/06

1LNN<ASIA>: M. Z(#/,-,E9,* - L*1(#/;$,* "CG:HFCJ> &@C:>: W0.5 T'9#2;# & O(# U.J.+JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 , 2004ISBN: 960-431-900-0,?GFCJ> ")E&U&1: 11134

+@HO:>: ?(/1,C(,9,2;# & ?(/1,C(#/0

H'<+,9,2;# 1LNN<ASIA>: @. R22'906 "CG:HFCJ> &@C:>: J/$4&'(6 O.#),E95 +JR:> & %<J9:> TCG:B8>: R80+# , 2007ISBN: 978-960-351-717-7,?GFCJ> ")E&U&1: 22904

+@HO:>: >(,.'<+,9,2;# 1LNN<ASIA>: K.R. L*1(#/;$56 "CG:HFCJ> &@C:>: W0.5 T'9#2;# & O(# U.J.

+JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 , 2000ISBN: 960-431-595-1,?GFCJ> ")E&U&1: 11133


+@HO:>: O5)'(%&'(6 J:#1),&)7+56 >(,.'<+,9,2;#6


K5),/1;.'(, T#+/)(, M1A/56 , 2010.


+@HO:>: J12#&.51(#/76 R&/0&'(6 J:#1),&)7+56 >(,.'<+,9,2;#6


K5),/1;.'(, T#+/)(, M1A/56 , 2010.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

102

E$1-2*2/ 1+/ E&'/ 3$&'&#$*(


1+’ ) 3 3 4 5



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

103

!-$E-2*2$,/


OH’ ! 1 0 1 2


U( /*1(4.'1'6 8')#.(/76 &., )A85)# #*.4 7<,*+ &.4<, .5+ -1,&722(&5 .3+ /E1(3+ 413+ ,

.3+ &*+85/%+ /#( .3+ 1493+ -,* #:,1,E+ &.5+ T#($#232(/0 .

!=<F=KJ7=9: H:L 7AMD7AH:> U( /*1(4.'1'6 '+4.5.'6 .,* )#80)#.,6 ';+#( ,( 'F06: 5 ,1(,87.5&5 .,* 2+3&.(/,E -'$;,* ,

5 C#&(/0 ,1,9,2;# /#( ,( C#&(/76 7++,('6 , ,( )78,$,( 71'*+#6 .56 T#($#232(/06 , 5

#-,.'9'&)#.(/0 $($#&/#9;# /#( )A85&5 , D5.0)#.# '/-#($'*.(/06 -,9(.(/06 , .,

'/-#($'*.(/4 &E&.5)# /#( ,( &.4<,( .,* , ,( 9'(.,*12;'6 .,* &<,9';,* , ,( &*+.'9'&.76 .56

'/-#($'*.(/06 $(#$(/#&;#6 , ., 712, , , 149,6 /#( 5 -1,&3-(/4.5.# .,* '/-#($'*.(/,E , .,

8'&)(/4 -9#;&(, /#( ,( $(#-1,&3-(/76 &<7&'(6 &.5 &<,9(/0 ),+A$#.

EFG6BC:LBA

,AH=<@9A ,=G<6CA, Z7/.,1#6.


+@HO:>: "FBAN?ND BH89 !AFGAN?NFCD - 1LNN<ASIA>: E87DH<8> %AHV8GD7:L - "CG:HFCJ> &@C:>: -S:F ,L<FAC@G8 -TH:> TCG:B8>: 2013- ISBN: 978-960-343-902-8- ,?GFCJ> ")E&U&1= 33155553


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,* )#80)#.,6: T#($#232(/0

1LNN<ASIA>: L#.'1;+# L'$1A/# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2013 (R+7/$,.'6

&5)'(%&'(6




!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

104

I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 2+%&'(6 , $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .'<+(/76 4-36 5 '12#&;# &'

,)A$'6 , ., -#;F(), 1493+ , 5 -1,&,),;3&5 , 5 &*D0.5&5 , /.9. I '(&025&5 <15&(),-,(';.#( '-(/,*1(/A &.(6 '+'125.(/76 '/-#($'*.(/76 .'<+(/76 /#( &*)-951%+'( .(6 2+%&'(6 -,*

<1'(AD'.#( +# #-,/.58,E+.

2OPBBA EFGABCAO@A>

J995+(/0


I #F(,9425&5 2;+'.#( )' 21#-.76 'F'.A&'(6 /#.A .(6 'F'.#&.(/76 -'1(4$,*6. L#8%6 .,

)A85)# &.51;D'.#( &' '+'125.(/76 /#( &*))'.,<(/76 )'84$,*6 )A85&56 , 5 -#1,*&;# /#(

&*))'.,<0 .3+ :,(.5.%+/.1(3+ &.(6 -#1#$4&'(6 8'31';.#( /'+.1(/06 &5)#&;#6 /#( 2(# .,+

942, #*.4 &*+*-,9,2;D'.#( &.5+ .'9(/0 #F(,9425&5 . J+#99#/.(/A , #+#.;8'+.#( )(/176

'12#&;'6 &' :,(.5.76/.1('6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

105

"!-22"4'-+$,/ -(-!+)U/ +*( 3$&"!$1+/'&(*(


OH’ ! 1 0 1 2


O., -9#;&(, .,* )#80)#.,6 -1,&'22;D,+.#( D5.0)#.# &<'.(/A )' .5+ -1,&3-(/0 #+A-.*F5

/#( ., 149, .56 /#.A .5+ '-#22'9)#.(/0 -1,'.,()#&;# /( #+A-.*F5 .3+ >(,'-(&.5)4+3+

&., &E2<1,+, '12#&(#/4 -'1(CA99,+ , )' &.4<, .5+ #-4/.5&5 $'F(,.0.3+ #+#D0.5&56

'12#&;#6 (C9 &E+.#F5 C(,21#:(/,E &5)'(%)#.,6 , '-#22'9)#.(/0 &*+7+.'*F5 ) /#(

&<'$(#&),E -'1#(.713 &-,*$%+ /#( &.#$(,$1,);#6 , &.,(<';# -,* $('*/,9E+,*+ .5+ '-#22'9)#.(/0 #- ,/#.A&.#&5 .3+ :,(.5.%+. T(, #+#9*.(/A , -1,&'22;D,+.#( ,( 'F06

8')#.(/76:


R. W5.0)#.# '-#22'9)#.(/06 #+A-.*F56 /#( $(#<';1(&56 &.#$(,$1,);#6 &., &E2<1,+,

'12#&(#/4 -'1(CA99,+.

>. R.,)(/46 J-#22'9)#.(/46 O<'$(#&)46 – T1,&3-(/A < #1#/.51(&.(/A - Z0B5

'-#22'9)#.(/%+ #-,:A&'3+ - J/-4+5&5 -1,&3-(/06 &.1#.52(/06 /#( &<'$;,* $1A&56 2(# .5 $(#<';1(&5 .56 &.#$(,$1,);#6

@. T1#/.(/76 $'F(4.5.'6 #+#D0.5&56 '12#&;#6 (>(,21#:(/4 O5)';3)#/ J-#22'9)#.(/0

O*+7+.'*F5 )

EFG6BC:LBA

,AH=<@9A ,=G<6CA, Z7/.,1#6.


+@HO:>: &<NA9?BFACD \LK:O:N@A CAF 1L7R=<FS:<6 - 1LNN<ASIA>: 'A<@A 3ACJOA CAF $?6998> (FC:O6:L - "CG:HFCJ> &@C:>: Rosili-TH:> TCG:B8>: 2012- ISBN: 978-960-89407-4-1- ,?GFCJ> ")E&U&1= 12257495



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

106


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,*

)#80)#.,6: '-#22'9)#.(/76 $'F(4.5.'6 .3+ C(,'-(&.5)4+3+

1LNN<ASIA>: L#.'1;+# L'$1A/#

+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2013 (R+7/$,.'6 &5)'(%&'(6


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 2+%&'(6 , $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .'<+(/76 4-36 5 '12#&;# &'

,)A$'6 , ., -#;F(), 1493+ , 5 -1,&,),;3&5 , 5 &*D0.5&5 , /.9. I '(&025&5 <15&(),-,(';.#(

'-(/,*1(/A &.(6 '+'125.(/76 '/-#($'*.(/76 .'<+(/76 /#( &*)-951%+'( .(6 2+%&'(6 -,*

<1'(AD'.#( +# #-,/.58,E+.

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 2;+'.#( )' 21#-.76 'F'.A&'(6 /#.A .(6 'F'.#&.(/76 -'1(4$,*6. L#8%6 .,

)A85)# &.51;D'.#( &' '+'125.(/76 /#( &*))'.,<(/76 )'84$,*6 )A85&56 , 5 -#1,*&;# /#( &*))'.,<0 .3+ :,(.5.%+/.1(3+ &.(6 -#1#$4&'(6 8'31';.#( /'+.1(/06 &5)#&;#6 /#( 2(#

.,+ 942, #*.4 &*+*-,9,2;D'.#( &.5+ .'9(/0 #F(,9425&5 . J+#99#/.(/A , #+#.;8'+.#( )(/176

'12#&;'6 &.,*6 :,(.5.76/.1('6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

107

2&($E$*'-+$,/

"56789: )/" ;<=>

.=?<@A>

;<=>

-BCDB8>

EFGACHFCI>

7:96G=>

':96G=>

ECTS

OH’ ! 3 3 4 5


H, )A85)# '(&A2'( .,*6 :,(.5.76 &., &E2<1,+, /#( 1#2$#;# 'F'9(&&4)'+, -'$;, .56

@,+($(3)#.(/06 , /#( '($(/4.'1# &.(6 ':#1),276 -,* &<'.;D,+.#( )' .5+ #+81%-(+5 *2';# ,

.5 C(,.'<+,9,2;# , .5+ ,(/,9,2;# , .5+ -'1(C#99,+.(/0 $(#<';1(&5 , .5+ 'F'9(/.(/0 C(,9,2;#

/.A. U( :,(.5.76 'F,(/'(%+,+.#( #/4)5 )' .5 <10&5 2,+($(3)#.(/%+ CA&'3+ $'$,)7+3+ /#( -1,C95)#.;D,+.#( -A+3 &.(6 58(/76 /#( /,(+3+(/76 $(#&.A&'(6 .56 2,+($(3)#.(/06

71'*+#6.


1) V&.,1;# .56 2,+($(3)#.(/06 '-(&.0)56 - O5)#+.(/4.'1'6 'F'9;F'(6 /#( ':#1),276

(O. ?-,*/,*CA9#)

2) @'+'.(/0 /#( :*&(/0 <#1.,21A:5&5 2,+($(3)A.3+

(O. ?-,*/,*CA9#)

3) O.1#.52(/76 #+#D0.5&56 &' 59'/.1,+(/76 CA&'(6 $'$,)7+3+

(O. ?-,*/,*CA9#)

4) H'<+,9,2;'6 2,+($(3)#.(/06 #9959,E<5&56

(O. ?-,*/,*CA9#)

5) H'<+,9,2;'6 2,+($(3)#.(/06 2,+,.E-5&56 )'2A956 /9;)#/#6

(O. ?-,*/,*CA9#)

6) ?'.#21#:3)#.(/0 /#( A99,( /9A$,( .3+ "omics" (-13.'Q+3)#.(/0 , )'.#C,9,)(/0

/.9.-.)

(O. ?-,*/,*CA9#)

7) H, T1421#))# .,* R+81%-(+,* @,+($(%)#.,6 /#( ,( &<'.(/76 'F'9;F'(6 &., -'$;,

.56 2,+($(3)#.(/06 .,* #+81%-,* (dbSNP, dbVar, dbGaP, HapMap, 1000 Genome project, ENCODE

/.9.-.)

(O. ?-,*/,*CA9#)

8) U2/,2,+($(3)#.(/0 - T1421#))# @,+($(3)#.(/06 .,* L#1/;+,*

(V. ?#1,*9A/,*)

9) Z'(.,*12(/0 2,+($(3)#.(/0 /#( J-(2,+($(3)#.(/0

(V. ?#1,*9A/,*)10) G#1)#/,2,+($(3)#.(/0 , H,F(/,2,+($(3)#.(/0 /#( K(#.1,:,2,+($(3)#.0



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

108

(O. ?-,*/,*CA9#)

11) ?(/1,C(#/0 2,+($(3)#.(/0 - T#8,2,+($(3)#.(/0 /#( U(/,2,+($(3)#.(/0

(O. ?-,*/,*CA9#)

12) O*2/1(.(/0 2,+($(3)#.(/0

(O. ?-,*/,*CA9#)13) I8(/76 , +,)(/76 /#( /,(+3+(/76 '-(-.%&'(6 .56 2,+($(3)#.(/06

(V. ?#1,*9A/,*)

!<ACHFCJ 7I<:>

!-,9,2(&.(/76 , '12#&.51(#/76 0 //#( :1,+.(&.51(#/76 #&/0&'(6 &' ,)A$'6 .3+ 20-25

:,(.5.%+. N):#&5 &.(6 &.1#.52(/76 #+#D0.5&56 2,+($(3)#.(/06 -951,:,1;#6 &' CA&'(6

$'$,)7+3+ , /#8%6 /#( &.(6 .17<,*&'6 ':#1),276 .56 2,+($(3)#.(/06. U( :,(.5.76

'12AD,+.#( #+'FA1.5.# /#( &' ,)A$'6 , *-4 .5+ /#8,$025&5 .,* $($A&/,+.#. O., .79,6 /A8' A&/5&56 , ,( :,(.5.76 #+#9#)CA+,*+ '-(-97,+ '12#&;# )' .5 ),1:0 21#-.06 7/8'&56.

EFG6BC:9H=>

'A<:LO6C:L $?699A , L#8520.1(# @'+'.(/06

'R:LC:LX6OA 1?H8<@A , J-;/,*1,6 L#8520.1(# ?,1(#/06 @'+'.(/06.


+@HO:>: 2:9FGFP7AHA - BQNK<:9=> =<=L98HFCI>

R<:B=NN@B=F> 1LNN<ASIA>: Brown H. R."CG:HFCJ> &@C:>: BROKEN HILL PUBLISHERS LTD+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010ISBN: 9603998563,?GFCJ> ")E&U&1: 1 3256614

+@HO:>: 0A<7AC:N:9FGF?7AHFCD CAF R<?H=Y9?7AHFCD: +A =<NAO=@A H8> =5AH:7FC=L7I98> FAH<FCD>

,?GFCJ> ")E&U&): 89223

TCG:B8 : 18 ICG./20101LNN<AS=@>: S.H.Y. WONG, M.W. LINDER, R. VALDESISBN: 978-960-394-721-9"CGJH8>: !-#$1$-(&) -(*()'/ ",E&+$,/

+@HO:>: R+#&*+$*#&)7+, DNA1LNN<ASIA>: Watson D.A. /# "CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.+JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-5-3,?GFCJ> ")E&U&1: 2625.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

109

187=FPB=F> 7AMD7AH:>

+@HO:>: 2:9FGF?7AHFCD ()OFCJ EFAOI5=?9)1LNN<ASIA>: EFG6BC:9H=> +JR:> & %<J9:> TCG:B8>: -O=5A9G<:QR:O8 2014

0LOO6GF: =<NABH8<FACP9 ABCDB=?9

+@HO:>: 2:9FGF?7AHFCD ()OFCJ CAF R<?HJC:OOA ABCDB=?9)

1LNN<ASIA>: EFG6BC:9H=> +JR:> & %<J9:> TCG:B8>: -O=5A9G<:QR:O8 2014

2OPBBA

J995+(/0 , R229(/0 .

EFGACHFCI> 7AM8BFACI> 7IM:G:F

K(#97F'(6 , )'97.5 '-(&.5),+(/06 C(C9(,21#:;#6 , #+#D0.5&5 &' CA&'(6 $'$,)7+3+.


T#1#/,9,E85&5 $(#97F'3+ , '12#&;'6 #&/0&'3+ , 21#-.76 'F'.A&'(6 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

110

#).'$1/ ,)++-#$,/1 4"$+&)#2$-1

"56789: )/" ;<=>

.=?<@A>

;<=>

-BCDB8>

EFGACHFCI>

7:96G=>

':96G=>

ECTS

OH’ ! 3 1 4 4


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) L#.#+45&5 .,* /*..#1(/,E /E/9,*.

C) JF,(/';3&5 .3+ :,(.5.%+ µ' .(6 C#&(/76 #1<76 -,* $(7-,*+ .,*6 µ,1(#/,E6 µ5<#+(&µ,E6

,2/,27+'&56.


H, )A85)# #-,.'9';.#( #-4 10 '+4.5.'6:

1. >(,9,2;# .,* /*..#1(/,E /E/9,*: 1E8)(&5 .56 -1,4$,* .,* /*..#1(/,E /E/9,* , .56

&E+8'&56 .,* DNA /#( .56 )(.3.(/06 $(#;1'&56

2. H# &5)';# '972<,* .,* /*..#1(/,E /E/9,*

3. U2/,2,+;$(# /#( o2/,2,+(/A /*..#1(/A &0 µ#.#

4. U2/,/#.#&.#9.(/A 2,+;$(#

5. U 149,6 .56 -13.'\+56 p53 &.5+ #-4/1(&5 .,* /*..A1,* &' /#1/(+,24+'6 C9AC'6

6. I #-%9'(# .56 -13.'\+56 p53 /#( ., :#(+4)'+, Warburg

7. L*..#1(/0 201#+&5 /#( /#1/(+(/0 'F#99#20

8. J+$,2'+0 /#( 'F32'+0 #-,-.3.(/A ),+,-A.(#

9. H# miRNA &.5 1E8)(&5 .56 /*..#1(/06 9'(.,*12;#6

10. I ),1(#/0 $(A2+3&5 &.,+ K #1/;+,

0<:9HFBH8<FACI> ABCDB=F>

T1,:,1(/0 -#1,*&;#&5 '1'*+5.(/%+ A1813+ &<'.(/%+ )' .5+ E95 .,* )#80)#.,6. K(A1/'(#

/A8' -#1,*&;#&56: 30 9'-.A.

EFG6BC:9H=>

K1. R97F56 @#9A+56 , J-. L#8525.06 ?,1(#/06 >(,9,2;#6

K1. P#:#09 O#+$#9.D4-,*9,6 , R+. L#8525.06 ?,1(#/06 >(,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

111


+@HO:>: Genes VIIV 1LNN<ASIA>: Lewin"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J

+JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2004ISBN: 960-88412-2-6,?GFCJ> ")E&U&1: 13003327

+@HO:>: +: ,QHHA<:: 'FA ':<FACD !<:BINNFB81LNN<ASIA> : Geoffrey M. Cooper & Robert E. Hausman"CG:HFCJ> &@C:>: -CAG87AYCI> "CGJB=F> $. 'R6BG<A &

1$- &." +JR:> & %<J9:> TCG:B8>: -O=5A9G<:QR:O8 , 58 /2011ISBN: 978-960-99895-8-9,?GFCJ> ")E&U&1: 33133232

2OPBBA J995+(/0 , R229(/0 .

EFGACHFCI> 7AM8BFACI> 7IM:G:F

K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class


T14,$,6 ('+$(Aµ'&5 'F7.#&5 ), 'F7.#&5 21#-.0 &., .79,6 .,* 'F#µ0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

112

2"("+$,/ -(.#*!&)


Z’ ) 4 3 5 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

O., -1421#))# &-,*$%+ ., )A85)# «@'+'.(/0 R+81%-,*» ';+#( <1,+(/A ., .'9'*.#;, #-4 .#

5 *-,<1'3.(/A )#80)#.# @'+'.(/06 -,* $($A&/,+.#( &., H)0)#. @(# .5+ '-(.*<0

-#1#/,9,E85&0 .,* 8'31';.#( #+#2/#;# 5 C#8(A /#.#+45&5 .56 C#&(/06 @'+'.(/06 5 ,-,;#

/#9E-.'.#( &.# )#80)#.# «@'+'.(/0 V» /#( «@'+'.(/0 VV», /#8%6 /#( «@,+($3)#.(/0 » /#( .3+

#1<%+ .56 «@'+'.(/06 T958*&)%+».

O.4<,6 .,* )#80)#.,6 ';+#( +# -#1,*&(A&'( .(6 #1<76 .56 @'+'.(/06 4-36 ':#1)4D,+.#(

&.,+ a+813-,. ?'2A9, )71,6 .,* )#80)#.,6 #:,1A ., 149, .56 @'+'.(/06 &.5+ #+81%-(+5

*2';# /#( .5+ #9959'-;$1#&5 C#&(/06 '-(&.5),+(/06 2+%&56 /#( /9(+(/06 ':#1),206.

T#1,*&(AD,+.#( '/.'+%6 5 2'+'.(/0 , ),1(#/0 /#( <13),&3)(/0 CA&5 /951,+,)(/%+

#&8'+'(%+ , /#1/;+,* , A993+ #&8'+'(%+ )' 2'+'.(/0 &*+(&.%&# , /#8%6 /#( A993+

-#8,9,2(/%+ /#.#&.A&'3+. O.5 $($#&/#9;# 2;+'.#( -#1,*&;#&5 .3+ C#&(/%+ #1<%+ , #99A

/#( '/.'+06 <10&5 -#1#$'(2)A.3+. H, )A85)# #22;D'( /#( /#9E-.'( .,*6 /9A$,*6 .56

2'+'.(/06 $(#2+3&.(/06 , 2'+'.(/06 &*)C,*9'*.(/06 /#( .,+ #+#$*4)'+, /9A$, .56

«2'+'.(/06 (#.1(/06» 0 «),1(#/06 (#.1(/06».


.=?<8HFCJ 7I<:>

• J(&#2320 &.5 @'+'.(/0 R+81%-,* – U 149,6 .56 @'+'.(/06 &.5+ *2';#

• ?'+.'9(/0 /951,+,)(/4.5.# <#1#/.013+ &.,+ A+813-, /#( ),+,2,+($(#/76

$(#.#1#<76

• R(),&:#1(+,-A8'('6

• >(,<5)(/0 /#( ),1(#/0 CA&5 .,* 2'+'.(/,E +,&0)#.,6

• G#1)#/,2'+'.(/0

• L*..#1,2'+'.(/0 - K(#.#1#<76 .3+ #*.,&3)(/%+ <13),&3)A.3+

• L*..#1,2'+'.(/0 - K(#.#1#<76 .3+ :*9'.(/%+ <13),&3)A.3+

• @'+'.(/0 .,* /#1/;+,* &.,+ A+813-, – ?,1:76 ,(/,2'+,E6 /#1/;+,* , /#1/(+(/A

&E+$1,)# (1'.(+,C9A&.3)# , ,(/,2'+06 /#1/;+,6 .,* )#&.,E & 3,85/%+ , ,(/,2'+06

-,9*-,$;#&5 .,* -#<7,6 '+.71,* , &E+$1,), Li-Fraumeni, &E+$1,), Von Hippel-Lindau, /.9) –

L*..#1,2'+'.(/0 .,* /#1/;+,* • L*..#1,2'+'.(/0 .,* /#1/;+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

113

• T958*&)(#/0 @'+'.(/0

• K(#.#1#<76 )' -,9*-#1#2,+.(/0 /951,+,)(/4.5.#

• L9(+(/0 2'+'.(/0 /#( 2'+'.(/0 &*)C,*90

• T1,2'++5.(/46 79'2<,6

• =#1.,21A:5&5 2,+($;3+ -,* ')-97/,+.#( &' 2'+'.(/76 +4&,*6 • L93+,-,;5&5 CA&'( 87&56

• T1421#))# #+A9*&56 .,* #+81%-(+,* 2,+($(%)#.,6

• I8(/A $(90))#.# &.5 @'+'.(/0 R+81%-,*

• @,+($(#/0 8'1#-';#


• G#1)#/,2'+'.(/0 (3 %1'6)

• R(),&:#(1(+,-A8'('6 /#( ?'&,2'(#/76 R+#();'6 (3 %1'6)• ?,1(#/0 K(A/1(&5 .,* GE9,* (3 %1'6)

0<:9HFBH8<FACI> -BCDB=F>:

• @'+'.(/0 O*)C,*9'*.(/0 - /9(+(/A -'1(&.#.(/A 2'+'.(/%+ #&8'+'(%+ /#( 5 $(#<';1(&0

.,*6 (3 %1'6)

• R+#9E&'(6 /':#9#;3+ C(C9;,* (book report) 0 A9956 '-(&.5),+(/06 C(C9(,21#:;#6 (3

%1'6)I -#1#/,9,E85&5 .3+ '12#&.51(#/%+ /#( :1,+.(&.51(#/%+ #&/0&'3+ ';+#( *-,<1'3.(/0 .

U( '12#&.51(#/76 /#( :1,+.(&.51(#/76 #&/0&'(6 -1#2)#.,-,(,E+.#( &*+0836 &' .7&&'1#

.)0)#.#. N<,*+ .1;315 $(A1/'(#.

EFG6BC:9H=>

2FA99:QO8> 0ACD> , J-;/,*1,6 L#8525.06 @'+'.(/06 R+81%-,*


+@HO:>: @'+'.(/0 R+81%-,* 1LNN<ASIA>: L3+. H1(#+.#:*99;$56 /#( R+ L,*CA.&5 "CG:HFCJ> &@C:>: R$'9:%+ L*1(#/;$5 +JR:> & %<J9:> TCG:B8 >: 2003ISBN:,?GFCJ> ")E&U&1: 6430



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

114

+@HO:>: @'+'.(/0 R+81%-,* 1LNN<ASIA>: M. R. T#.#12(A /#( >. @. R9'-41,* "CG:HFCJ> &@C:>: J/$4&'(6 O*))'.1;# +JR:> & %<J9:> TCG:B8>: 2005ISBN:

,?GFCJ> ")E&U&1: 45347

+@HO:>: V#.1(/0 @'+'.(/0 Thompson & Thompson1LNN<ASIA>: Nussbaum, McInnes, Willard"CG:HFCJ> &@C:>: J/$4&'(6 T. =. T#&<#9;$56 +JR:> & %<J9:> TCG:B8>: 2011ISBN:,?GFCJ> ")E&U&1: 13256587

+@HO:>: O.,(<';# J:#1),&)7+56 @'+'.(/06 .,* R+81%-,* , >^ 7/$,&5

1LNN<ASIA>:"CG:HFCJ> &@C:>: J/$4&'(6 University Studio Press+JR:> & %<J9:> TCG:B8>: 2009ISBN:,?GFCJ> ")E&U&1: 17522

2OPBBA EFGABCAO@A>

I $($#&/#9;# 2;+'.#( /*1;36 &.# '995+(/A. Y&.4&, &.# -9#;&(# #+#:,1%+ , :1,+.(&.51;3+ ,

0 A993+ '12#&(%+ , #-#(.';.#( #-4 .,*6 :,(.5.76 +# <15&(),-,(0&,*+ F'+4293&&'6 -5276

/#( C(C9(,21#:;#. O*+0836 #*.4 -'1(9#)CA+'( )'97.5 , /#.#+45&5 /#( <10&5 '-(&.5),+(/%+ A1813+ , /':#9#;3+ C(C9;3+ 0 A9956 C(C9(,21#:;#6 &.5+ #229(/0 29%&&#.


U( -#1#$4&'(6 2;+,+.#( )' .14-, -,* +# '+8#11E+,*+ .5+ '+'120 &*))'.,<0 .3+ :,(.5.%+

&.5 $($#/.(/0 $(#$(/#&;#. O.4<,6 ';+#( );# (&,11,-;# #+A)'&# &., $#&/#9,/'+.1(/4 /#( &.,

)#85.,/'+.1(/4 ),+.79, $($#&/#9;#6.

O., -1#/.(/4 &/79,6 .,* )#80)#.,6 , $59#$0 &.(6 '12#&.51(#/76 /#( :1,+.(&.51(#/76 #&/0&'(6 , <15&(),-,(';.#( 5 #+#/#9*-.(/0 )78,$,6. ?'2A95 &5)#&;# $;+'.#( &.5

$5)(,*12;# &/'-.4)'+3+ '-(&.5)4+3+ , 2(’ #*.4 -1,CA99'.#( 5 '-(&.5),+(/0 )78,$,6

$('1'E+5&56 -,* -'1(9#)CA+'( -#1#.015&5 , $(#)41:3&5 *-48'&56 /#( -'(1#)#.(/4

79'2<, .56 *-48'&56.


I #F(,9425&5 2;+'.#( /*1;36 )' 21#-.0 'F7.#&5 &., .79,6 .,* 'F#)0+,* /#( /#.A .(6 '-4)'+'6 'F'.#&.(/76 -'1(4$,*6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

115

J-(-97,+ , 2;+'.#( #F(,9425&5 .3+ #+#:,1%+ -,* -1,'.,()AD,*+ ,( :,(.5.76 2(# /A8'

'12#&.51(#/0 A&/5&5 .

RF(,9,2,E+.#( ,( 21#-.76 '12#&;'6 /#( ,( -1,:,1(/76 -#1,*&(A&'(6 #*.%+.

H79,6 , '/.()%+.#( 5 '+'125.(/0 &*))'.,<0 &.(6 -#1#$4&'(6 , &.# '12#&.01(# /#( &.(6

*-49,(-'6 $1#&.51(4.5.'6 .,* )#80)#.,6 , /#8%6 /#( 5 (/#+4.5.# &*+$*#&.(/06 &/7B56 /#( #+'FA1.5.56 '12#&;#6 &.# '12#&.01(#.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

116

-(-!+)U/ "0-#'&2*( +*( 3$&"!$1+/'*( 1+/( )2"$-


Z’ ) 3 2 4 6


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) "# '(&A2'( .,*6 :,(.5.76 &.(6 #1<76 -,* $(7-,*+ .5+ ':#1),&)7+5 71'*+# /#( #+A-.*F5

&' &E2<1,+# -'$;# .56 C(,Q#.1(/06 '-(&.0)56.

C) "# -'1(21AB'( -%6 5 C#&(/0 71'*+# &*+$7'.#( )' .5 C(,)5<#+(/0 0 /9(+(/0 ':#1),20 .

2) "# #+#-.EF'( 7++,('6 , 4-36 5 /#(+,.,);# , 5 /#.,<E13&5 .56 -+'*)#.(/06 ($(,/.5&;#6 , 5

$(#<';1(&5 .56 -,(4.5.#6 &., C(,)5<#+(/4 /#( /9(+(/4 '12#&.01(, , 5 $(#<';1(&5 -413+ &'

,12#+(&),E6 -,* -1,A2,*+ .5+ ':#1),&)7+5 71'*+#.

$) "# -#1,*(A&'( ., 1*8)(&.(/4 -9#;&(, -,* $(7-'( .5+ #+A-.*F5 ':#1),2%+ &.5+ *2';#.

') "# -#17<'( C#&(/0 2+%&5 &<'.(/A )' .(6 'F'9;F'(6 /#( .# .'<+,9,2(/A '-(.'E2)#.# .56

&E2<1,+56 ':#1),&)7+56 C(,Q#.1(/06 '-(&.0)56 /#( +# )'.#$%&'( &.,*6 :,(.5.76 ., )0+*)# 4.( ., &*2/'/1()7+, -'$;, )-,1'; +# #-,.'97&'( .,+ #*1(#+4 <%1, '-#22'9)#.(/06

&.#$(,$1,);#6 .,*6.


.=?<8HFCJ 7I<:>

?71,6 V: K;9 28 J$D()# ?'0<1$ D281 0L$'"&-#

• V&.,1(/0 #+#$1,)0 /#( .'<+,9,2(/0 'F79(F5 .56 ':#1),&)7+56 C(,Q#.1(/06 '-(&.0)56 /#(

C(,.'<+,9,2;#6 (3 %1'6).

• L#(+,.,);# /#( /#.,<E13&5 .56 -+'*)#.(/06 ($(,/.5&;#6 (3 %1'6).

• R1<76 $(,;/5&56 , <15)#.,$4.5&56 /#( $(#<';1(&56 -413+ &' ,12#+(&),E6 -,* -1,A2,*+ .5+

':#1),&)7+5 71'*+# /#( /#(+,.,);# , )' AF,+# .(6 C(,Q#.1(/76 '-(&.0)'6 /#( .5

C(,.'<+,9,2;# (3 %1'6).

?71,6 VV: K1C;2<G8 0L$'"&-=1 "0 CG&1$ 28 "&'($)# -0102()# 7(C-1BD8

• H, 1*8)(&.(/4 -9#;&(, - ,* $(7-'( .5+ #+A-.*F5 /#( ':#1),20 .3+ in vitro $(#2+3&.(/%+

-1,Q4+.3+ &.(6 I.T.R. /#( .5+ J.J. (3 %1'6).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

117

• O*&.0)#.# $(#<';1(&56 .56 -,(4.5.#6 &., C(,)5<#+(/4 /#( /9(+(/4 '12#&.01(, – @'+(/76

#1<76 #&:A9'(#6 &., '12#&.01(, (3 %1'6).

• OE2<1,+'6 .'<+,9,2;'6 #+;<+'*&56 /#( <#1#/.51(&),E +,*/9'Q/%+ ,F73+ )' &/,-4 .5

),1(#/0 2'+'.(/0 $(A2+3&5 (9 %1'6): 1) J:#1),276 &.5+ /9(+(/0 )(/1,C(,9,2;# , 2) &.,+

-958*&)(#/4 2'+'.(/4 79'2<, (-1495B5 2'+'.(/%+ +,&5)A.3+ , 2,+;$(# -1,$(A8'&56), 3)

&.,+ -1,2'++5.(/4 /#( -1,'):*.'*.(/4 2'+'.(/4 79'2<, , 4) &.5+ (#.1,$(/#&.(/0 .

?71,6 VVV: K1C;2<G8 0L$'"&-=1 "0 CG&1$ 2(* DH-M'&10* E0'$;0<2()?* ;'&D0--.D0(*

• H, 1*8)(&.(/4 -9#;&(, -,* $(7-'( .5+ #+A-.*F5 +73+ :#1)A/3+ &.(6 I .T.R. /#( .5+ J.J. (3

%1'6).

• H# &.A$(# #+A-.*F56 '+46 +7,* :#1)A/,* /#( ,( /9(+(/76 $,/()76 .,* (3 %1'6).

• I &*)C,90 .3+ C(,'-(&.5)%+ &.5+ #+A-.*F5 /#( /9(+(/0 $,/()#&;# '+46 +7,* :#1)A/,* (9-12 %1'6): 1) H#*.,-,;5&5 /#( '-(/E13&5 +73+ :#1)#/'*.(/%+ &.4<3+ , &<'$(#&)46

:#1)A/3+ , 2) :#1)#/,2'+'.(/0 /#( :#1)#/,2,+($(3)#.(/0 , 3) +7'6 &.,<'*)7+'6

8'1#-';'6 /#.A .,* /#1/;+,* , 4) #+#&*+$*#&)7+'6 -13.'Q+'6 /#( ),+,/93+(/A

#+.(&%)#.# 36 8'1#-'*.(/,; -#1A2,+.'6 , 5) 8'1#-'*.(/76 ':#1),276 .3+ .'<+,9,2(%+

.3+ #+.(+,5)#.(/%+ +,*/9'Q/%+ ,F73+ , .3+ 1(C,'+DE)3+ /#( .56 RNA -#1')C,906 , 6)

#+#&*+$*#&)7+# ')C49(# /#( ')C49(# DNA, 7) 2,+($(#/0 8'1#-';# , 8) /#8,$025&5 :#1)A/,*

&.,+ (&.4-&.4<,.

)R:K<=?HFCI> -BCDB=F>

1. !"#$%&'(' )*+),"()-./'0 (3 %1'6 , 3-4 .)0)#.#): ?'97.5 /#( -#1,*&;#&5 $(-93)A.3+

'*1'&(.'<+;#6 -,* #+#:71,+.#( &' /#(+,.,);'6 .56 &E2<1,+56 C(,Q#.1(/06 '-(&.0)56 /#(

C(,.'<+,9,2;#6.

2. 12+)/0 #2* #+2342*. (5. )6'+&2,&7.5 7+)*.' 8'" 8'".2(2&/' ,(2 #)9/2 (50 *4)/'0 (3

%1'6 , 3-4 .)0)#.#): R+#D0.5&5 /#( -#1,*&;#&5 -951,:,1;#6 &<'.(/A )' C(,.'<+,9,2(/76 /#(

:#1)#/'*.(/76 '.#(1';'6 , .'<+,9,2(/A -A1/# , $5)4&(,*6 1*8)(&.(/,E6 ,12#+(&),E6

:#1)A/3+ /#( (#.1,.'<+,9,2(/%+ C,585)A.3+ , ,12#+(&),E6 /#.,<E13&56 .56 -+'*)#.(/06

($(,/.5&;#6 /.9.-.

3. :*,(;&'(' 9"'-)/+",50 (50 #2"<(5('0 (3 %1'6 , 3-4 .)0)#.#): !-,87.,+.#6 4.( #-,.'9,E+

.5+ ,)A$# -,* #+#9#)CA+'( .5+ #+A-.*F5 )(#6 /#(+,.4),* $(#2+3&.(/06 .'<+,9,2;#6 &' 7+#

C(,)5<#+(/4 '12#&.01(, J& R , ,( :,(.5.76 '12AD,+.#( -A+3 &., &<'$(#&)4 /#( .5+ ':#1),20

.3+ $(#$(/#&(%+ -,* #-#(.,E+.#( 2(# .5+ *9,-,;5&5 '+46 '1'*+5.(/,E 712,* &.# -9#;&(#

.*-,-,(5)7+,* &*&.0)#.,6 $(#<';1(&56 .56 -,(4.5.#6. T#1A9959# , 'F,(/'(%+,+.#( )' .,

C(,)5<#+(/4 &<'$(#&)4 /#( .5+ #+A-.*F5 )(#6 +7#6 $(#2+3&.(/06 .'<+,9,2;#6 /#( &.5

&*+7<'(# &*+.A&&,*+

7/8'&5

&<'.(/A

)'

.5+

-'1#(.713

':#1),20

.56

&'

A99#

-#14),(#

712#.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

118

4. =.'>;(5,5 #$5+262+/'0 ,) ?3,)"0 9)92&7.@. (3 %1'6 , 3-4 .)0)#.#): !-,87.,+.#6 4.(

#-,.'9,E+ )795 )(#6 ,)A$#6 -,* '12AD'.#( -A+3 &.5+ .#*.,-,;5&5 /#( '-(/E13&5 +73+

:#1)#/'*.(/%+ &.4<3+ )' &/,-4 .5+ #+A-.*F5 &.,<'*)7+3+ 8'1#-'(%+ /#.A .,* /#1/;+,* ,

,( :,(.5.76 /#8,$52,E+.#( &.5+ #+#D0.5&5 -951,:,1;#6 &' 'F'($(/'*)7+'6 CA&'(6

$'$,)7+3+ &., $(#$;/.*,. O.5 &*+7<'(# , '/87.,*+ &' 21#-.0 #+#:,1A .5 )'8,$,9,2;# -,* #/,9,E85&#+ , /#8%6 /#( .,*6 .14-,*6 )' .,*6 ,-,;,*6 -(&.'E,*+ 4.( #*.0 'F*-51'.'; .,

&/,-4 .,*6.

5) A+4',(5+"'8; )6'+&24; 8'".2(<&2* ()-."8;0 &2+"'8;0 4).)("8;0 9"34.@,50 (3 %1'6 , 3-4

.)0)#.#): !-,87.,+.#6 4.( #-,.'9,E+ )795 '+46 /9(+(/,E '12#&.51;,* -,* 'F'($(/'E'.#(

&.5 ),1(#/0 2'+'.(/0 $(A2+3&5 , ,( :,(.5.76 'F,(/'(%+,+.#( )' .5+ ':#1),20 )(#6 /#(+,.4),*

.'<+,9,2;#6. R:,E -1#2)#.,-,(0&,*+ .# &<'.(/A -'(1A)#.# , &*+.A&&,*+ #+#:,1A 4-,*

-'1(21A:,*+ .5 $(#$(/#&;# /#( #F(,9,2,E+ .# #-,.'97&)#.A .56 , .(6 $*+#.4.5.'6

-1,&#1),206 .56 &' A99'6 $(#2+3&.(/76 ':#1),276 , /#8%6 /#( .# -9',+'/.0)#.# 0 )'(,+'/.0)#.A .56.

EFG6BC:9H=>

1?H8<@A 'R:LC:LX6OA , J-;/,*1,6 L#8520.1(# ?,1(#/06 @'+'.(/06.


+@HO:>:

G#1)#/,2,+($(3)#.(/0 /#(

T13.'Q+3)#.(/0

1LNN<ASIA>: S.H.Y. WONG, M.W. LINDER, R. VALDES"CG:HFCJ> &@C:>: TRPVOVR"U! RJ +JR:> & %<J9:> TCG:B8>: 15 7/$./2010ISBN: 978-960-394-721-9,?GFCJ> ")E&U&1: 89223

+@HO:>: ?,1(#/0 $(#2+3&.(/0 1LNN<ASIA>: T#.1(+46 @. T.,Ansorge Wilhelm "CG:HFCJ> &@C:>: TRPVOVR"U! RJ

+JR:> & %<J9:> TCG:B8>: 15 7/$./2008ISBN: 978-960-394-534-5,?GFCJ> ")E&U&1: 41544

+@HO:>: J:#1),276 ?,1(#/06 K(#2+3&.(/06 1LNN<ASIA>: T9#2'1A6 T., @'1,C#&;95 R.,

T#-#Q3A++,* R. "CG:HFCJ> &@C:>: BROKEN HILL PUBLISHERS LTD +JR:> & %<J9:> TCG:B8>: 15 7/$./2011 ISBN: 9789604891887 ,?GFCJ> ")E&U&1: 13256969



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

119

+@HO:>: U(/,+,);#-K;/#(, &.5 >(,9,2;#. N):#&5 &.5 C(,.'<+,9,2;#

1LNN<ASIA>: HPVR"HRG!ZZVKIO LY"OHR"HV"UO "CG:HFCJ> &@C:>: JLKUHVLUO UVLUO RKJZGY" L!PVRLVKI R.J. +JR:> & %<J9:> TCG:B8>: 1/2006


+@HO:>: R+A-.*F5 J:#1),2%+ .3+ >(,'-(&.5)%+ &.5+ !2';#

1LNN<ASIA>: O3.51;# ?-,*/,*CA9# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , ?A1.(,6 2004('/.'.#)7+'6 '.0&('6 '-(/#(1,-,(0&'(6 7/.,.')


+@HO:>: U$52;'6 '/-4+5&56 '12#&(%+ .,* )#80)#.,6

1LNN<ASIA>: O3.51;# ?-,*/,*CA9# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , ?A1.(,6 2004('/.'.#)7+'6 '.0&('6 '-(/#(1,-,(0&'(6 7/.,.')

2OPBBA EFGABCAO@A>

J995+(/0 , '-'F'12#&;# C(C9(,21#:;#6 &.5+ R229(/0 .


K(#97F'(6 , :1,+.(&.51(#/76 #&/0&'(6 , *-,9,2(&.(/0 A&/5&5 , '12#&.51(#/0 A&/5&5 .

J-'F'12#&;# '-(&.5),+(/06 C(C9(,21#:;#6 , $(-93)A.3+ '*1'&(.'<+;#6 , #+#D0.5&5

&<'.(/06 -951,:,1;#6 &., $(#$;/.*, /#( ($(#;.'1# &' CA&'(6 $'$,)7+3+. O*221#:0

'12#&(%+ /#( '/87&'3+ , /#8%6 /#( -1,:,1(/76 -#1,*&(A&'(6.


@1#-.76 'F'.A&'(6 'F#)0+,* (80% .,* .'9(/,E C#8),E), '-;$,&5 &.(6 #&/0&'(6 .,*

)#80)#.,6 (20% .,* .'9(/,E C#8),E).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

120

'&#$-,/ (")#&3$&4&2$-


Z’ ) 3 0 3 4


O.4<,( .,* )#80)#.,6 ';+#(:

#) "# #-,/.0&,*+ ,( :,(.5.76 C#&(/76 2+%&'(6 .56 M,1(#/06 B(,9,2;#6 .,* +'*1%+#

C) "# )'9'.0&,*+ ,( :,(.5.76 .,*6 C#&(/,E6 ),1(#/,E6 )5<#+(&),E6 -,* $(7-,*+ .5+

R+A-.*F5 /#( .5 Z'(.,*12;# .,* "'*1(/,E O*&.0)#.,6

2) "# )'9'.0&,*+ ,( :,(.5.76 .5 ),1(#/0 CA&5 '-(9'2)7+3+ #&8'+'(%+ .,* "'*1(/,E

O*&.0)#.,6.


.=?<8HFCJ 7I<:>

• I ?,1(#/0 >(,9,2;# .,* +'*1%+# .

• ?,1(#/,; /#( /*..#1(/,; )5<#+(&),; -,* $(7-,*+ .5 &*+#-.(/0 $(#C;C#&5 .

• J-#2320 /#( U12A+3&5 .,* "'*1(/,E O*&.0)#.,6.

• @7++5&5 /#( '-(C;3&5 .3+ +'*1(/%+ /*..A13+.

• L#8,$025&5 .3+ +'*1#F4+3+ &.,*6 &.4<,*6 .,*6.

• O<5)#.(&)46 &*+AB'3+ /#( 1E8)(&5 .3+ &*+#-.(/%+ &*+$7&'3+.

• I ?,1(#/0 >(,9,2;# .56 4&:15&56 (M59#&.(/A/ Drosophila ) .

• @,+;$(# /#( &*)-'1(:,1A.

• I 29%&&# /#( ,( #:#&;'6.

• L*..#1(/,; )5<#+(&),; )A85&56 /#( )+0)56 – >(,9,2(/0 CA&5 .56 #.,)(/4.5.#6.

• K(#.#1#<76 .56 &/7B56: O<(D,:17+'(# • @01#+&5 .,* '2/':A9,* – a+,(# .E-,* Alzheimer.

" I J+,.5.# ?,1(#/0 >(,9,2;# .56 4&:15&56 #+#9E'.#( #-4 :,(.5.76 ,( ,-,;,(

#+#9#)CA+,*+ &' '8'9,+.(/0 CA&5 .5+ -1,:,1(/0 -#1,*&;#&5 '12#&(%+ -,*

/#9E-.,*+ .5+ '+4.5.#.

EFG6BC:LBA

'. 2<8N:<@:L , R+#-951%.1(# L#8520.1(# ?,1(#/06 >(,9,2;#6- R+#-.*F(#/06 >(,9,2;#6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

121


+@HO:>: >#&(/76 #1<76 +'*1,'-(&.5)%+ 1LNN<ASIA>: Kandel Eric R.,Schwartz James H.,Jessell Thomas M"CG:HFCJ> &@C:>: JLKUOJVO T. =. TRO=RZVKIO +JR:> & %<J9:> TCG:B8>: 15 2004ISBN: 9603992135,?GFCJ> ")E&U&1: 45097.

+@HO:>: "'*1,'-(&.0)5 /#( O*)-'1(:,1A 1LNN<ASIA>: Kandel Eric R., Schwartz James H.,Jessell Thomas M"CG:HFCJ> &@C:>: TR"JTVOHI?VRLJO JLKUOJVO LPIHIO +JR:> & %<J9:> TCG:B8>: 15 2009ISBN: 978-960-524-075-2,?GFCJ> ")E&U&1: 467


+@HO:>: ?,1(#/0 "'*1,C(,9,2;#- T#1,*&(A&'(6 )#80)#.,6 1LNN<ASIA>: ?. @152,1;,* +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011 –


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &.,

)A85)# <15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, ,

:,(.5.06 $'+ #-,/.A )4+, 2+%&'(6 , #99A #+#-.E&&'( /#( (/#+4.5.'6 -,* .,* '-(.17-,*+

+# &<'$(AD'( -'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&,

/#( )' ., $($A&/,+.#.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.

J;+#( -1,#(1'.(/0 5 '/-4+5&5 '12#&;#6 5 ,-,;# -#1,*&(AD'.#( -1,:,1(/A.

O' -'1;-.3&5 '12#&;#6 ., 10% .,* C#8),E #81,;D'.#( )' ., C#8)4 .,* )#80)#.,6

-1,/'()7+,* +# *-,9,2(&.'; , .'9(/46 C#8)46.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

122

!#*+"&'$,/


Z’ ) 3 1 4 4



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

123

+"%(&4&2$- '&#$-,/1 3$&4&2$-1


Z’ ) 3 0 3 4


O.4<,( .,* )#80)#.,6 ';+#(:

#) N# 2+31;&,*+ ,( :,(.5.76 .(6 #1<76 &.(6 ,-,;'6 &.51;D,+.#( ,( &5)#+.(/4.'1'6

.'<+(/76 #(<)06 .56 ?,1(#/06 >(,9,2;#6 C) "# /#.#+,0&,*+ .(6 ':#1),276 .3+ .'<+(/%+ #*.%+ &.5 C#&(/0 /#( &.5+ ':#1),&)7+5

71'*+#

2) "# /#.#+,0&,*+ .(6 -1#/.(/76 ':#1),276 .3+ .'<+(/%+ #*.%+ &' $(A:,1,*6 .,)';6

4-36 5 !2';# , 5 @'312;# /.9.-.


A19282$ > : :2'$28-()?* DC'BD8* J(J,(&E8)=1 .

1. !C1($,-,;5&5 C(C9(,85/%+ )' )41(# &5)#&)7+,* +,*/9'Q/,E ,F7,6.2. OA13&5 C(C9(,85/%+ )' .5+ .'<+(/0 PCR.

3. ?78,$,( -,* C#&;D,+.#( &.5+ #+;<+'*&5 .56 -13.'\+56 -,* -#1A2'( , '-(8*)5.46

/9%+,6.

A19282$ II: %02$,,$G(-?10D8 in vitro.

1. M'.#99#F(27+'&5 '($(/06 87&56.

2. K5)(,*12;# .*<#;3+ )'.#99AF'3+ in vitro.

A19282$ >>> : N)L'$D8 ;'B20F1=1 D281 A . coli.

1. ?5<#+(&)46 9'(.,*12(A6 .3+ :,173+ pBAD.2. ?5<#+(&)46 9'(.,*12(A6 .3+ :,173+ pJH.

3. ?5<#+(&)46 9'(.,*12(A6 .3+ :,173+ pLEX.

4. R-,)4+3&5 .3+ #+#&*+$*#&)7+3+ -13.'Q+%+.

A19282$ > V: I<22$'()?* D0('?* , 0(D$-B-# DNA )$( ?)L'$D8 ;'B20F1=1 D0 0<)$'<B2()C

)H22$'$ .

1. L*..#1(/76 &'(176.

2. K(#)49*+&5 D3(/%+ /*..A13+.

3. ?49*+&5 D3(/%+ /*..A13+ )' (Q/,E6 :,1';6.

4. K';/.'6 '-(9,206.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

124

A1&282$ V: /0102()C 2'&;&;&(8"?1$ E8,$D2()C .

1. K(#2,+,+($(#/A D%#.

2. O.4<'*&5 2,+($;,*.

A19282$ VI: /0102()C 2'&;&;&(8"?1$ L<2C

1. L#.#&/'*0 $(#2,+($(#/%+ :*.%+ )' .5 C,08'(# .,* -9#&)($;,* Ti.2. L#.#&/'*0 $(#2,+($(#/%+ :*.%+ )' .5 C,08'(# (%+.

3. L#.#&/'*0 $(#2,+($(#/%+ :*.%+ )' #-'*8';#6 )'.#:,1A DNA

4. PE8)(&5 .56 7/:1#&56 $(#2,+($;3+.

5. I '/)'.A99'*&5 .3+ $(#2,+($(#/%+ :*.%+ &' ')-,1(/4 '-;-'$,.

A19282$ VII Microarrays )$( RNAi.

1. Microarrays ()(/1,$(#.AF'(6).

2. RNA interference (RNAi).

A19282$ VIII: AL$'"&-?* 28* 20M1&,&-.$* 2&< $1$D<17<$D"?1&< DNA D2&1 2&"?$ 28* <-0.$* .1. U( #9959,*<;'6 .3+ +,*/9'Q/%+ ,F73+ 36 $(#2+3&.(/A '12#9';#.

2. T13.'\+'6 -,* $1,*+ 36 :A1)#/#.

3. K(#2,+($(#/A D%# 36 ),+.79# #&8'+'(%+.

4. @,+($(#/0 8'1#-';#.

5. M'1#-'*.(/0 /93+,-,;5&5 .

6. J)C49(#.

7. V#.1,$(/#&.(/0 .

EFG6BC:9H=>

2. 1C6XG8> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6.

'. 2<8N:<@:L , A +#-951%.1(# L#8520.1(# ?,1(#/06 >(,9,2;#6 – R+#-.*F(#/06 >(,9,2;#6.


+@HO:>: R+#&*+$*#&)7+, DNA1LNN<ASIA>: Watson D.A. /# "CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.

+JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-5-3,?GFCJ> ")E&U&1: 2625.

+@HO:>: J12#&.51(#/,; *-,9,2(&),; &.(6 C(,9,2(/76 '-(&.0)'6

1LNN<ASIA>: Lisa Seidman"CG:HFCJ> &@C:>: R/#$5)#Q/76 J/$4&'(6 V. ?-A&$1# & OVR U.J.+JR:> & %<J9:> TCG:B8>: 15 2010ISBN: 978-960-88412-9-1,?GFCJ> ")E&U&1: 5319



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

125


+@HO:>: T#1,*&(A&'(6 )#80)#.,6 H'<+,9,2;# ?,1(#/06 >(,9,2;#6 1LNN<ASIA>: @. O/AC$56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010 –


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &.,

)A85)# <15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, ,

:,(.5.06 $'+ #-,/.A )4+, 2+%&'(6 , #99A #+#-.E&&'( /#( (/#+4.5.'6 -,* .,* '-(.17-,*+

+# &<'$(AD'( -'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&,

/#( )' ., $($A&/,+.#.


U( :,(.5.76 #F(,9,2,E+.#( )' 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

126

!"#$"%&'"(&

"!$4"2&'"(*(

'-./'-+*(

&76GA -



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

127

'&#$-,/ &$,&4&2$-


]’ " 2 0 2 2


U &.4<,6 .,* )#80)#.,6 ';+#( 5 -1,&722(&5 '+46 +7,* /9A$,* .56 ,(/,9,2;#6 , #*.,E . 56

),1(#/06 ,(/,9,2;#6. I ),1(#/0 ,(/,9,2;# #-,&/,-'; &.5 )'97.5 .56 ':#1),206 ),1(#/%+

$'(/.%+ (/#+%+ +# -1,&'22;&,*+ &*2/'/1()7+# ,(/,9,2(/A /#( 'F'9(/.(/A -1,C90)#.# /#(

&.5+ #+A-.*F5 +73+ .'<+,9,2(%+ -,* '-($(%/,*+ +# $%&,*+ +7'6 8'315.(/76 /#( -1#/.(/76

CA&'(6 &.# 87)#.# -,* -1,&'22;D'(. I ':#1),20 .'<+(/%+ ),1(#/06 C(,9,2;#6 /#( 2'+'.(/06

2(# .5+ '-;9*&5 ,(/,9,2(/%+ -1,C95)A.3+ $;+'( +7# $(A&.#&5 &., -%6 #9959'-($1,E+

)'.#FE .,*6 ,( $E, /9A$,(. I #+A$'(F5 .,* -#1#-A+3 ';+#( /#( , /E1(,6 &.4<,6 .,* )#80)#.,6

/#( $(/#(,9,2'; .5+ E-#1F5 /#( #+#2/#(4.5.# $($#&/#9;#6 .,* &' :,(.5.76 ),1(#/06

C(,9,2;#6.


M'315.(/4 )71,6 • I &E2<1,+5 87&5 .56 ,(/,9,2;#6 /#( 5 &<7&5 .56 )' A99,*6 .,)';6 .56 C(,9,2;#6

• R1<76 'F'9(/.(/06 8'31;#6 - O<,976 2'+'.(/06 -,(/(94.5.#6 – T1,&#1),20 -

J($,27+'&5

• U(/,9,2(/46 /#8,1(&)46 .56 'F79(F56. U1(&)46 .56 ),1(#/06 ,(/,9,2;#6. ?,1(#/,;

$';/.'6.

• ?,1(#/0 &*&.5)#.(/0 /#( :*9,27+'&5

• T958*&)(#/0 2'+'.(/0

• G*9,2'321#:;#

• ?,1(#/0 'F79(F5 /#( -1,&#1),20

• ?,1(#/0 CA&5 .56 &*)-'1(:,1A6

• U(/,9,2;# .56 $(#.015&56

• @'+'.(/A .1,-,-,(5)7+,( ,12#+(&),;

EFG6BC:LBA

'. -O=5@:L %AHV6C8 , J-;/,*1,6 L#8520.1(# O*&.5)#.(/06 /#( U(/,9,2;#6 <'1&#;3+

,12#+(&)%+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

128


• An Introduction to Molecular Ecology. Travor J.C. Beebee & Graham Rowe. Oxford University Press,

2004

• &FC:O:N@A. K5)0.156 >'1'&429,*. 40'(L . A)79D0(* « ?,,$ », 2004

• "5=OFCHFCD 3F:O:N@A. D.J. Futuyama, 4$1 . A)7 . I'#28* , 1991

• Molecular Markers, Natural History, and Evolution. John C. Avise, 2nd edition, Sinauer

Associates, 2004

• Advances in Molecular Ecology. Gary R. Carvalho , IOS Press, 1998

• "5=OFCHFCD :FC:O:N@A. Eric R. Pianka, 4$1 . A)7 . I'#28* , 2006

($'+ $(#.;8'+.#( &.,+ J*$,F,)


K(#97F'(6 /#( &')(+A1(# #-4 '-(&/7-.'6 /#8525.76


T#1,*&(A&'(6 :,(.5.%+/ &')(+A1(# 0 //#( 21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

129

$&4&2$-


W’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:#) +# #-,/.0&,*+ ,( :,(.5.76 2'+(/76 2+%&'(6 2(# .,*6 (,E6 /#( ($(#;.'1# 2(# .,*6 C#&(/,E6

),1(#/,E6 )5<#+(&),E6 -,* '972<,*+ .(6 #9959'-($1A&'(6 (%+-F'+(&.%+.

C) +# #-,/.0&,*+ 2+%&'(6 2(# .5 C(,9,2;# &*2/'/1()7+3+ ,(/,2'+'(%+ (%+ ,2) +# /#.#+,0&,*+ 4.( ,( (,; #-,.'9,E+ (&<*1A '1'*+5.(/A '12#9';# &., -'$;, .56

)'.#:1#&.(/06 (#.1(/06 (2,+($(#/0 8'1#-';#/#+A-.*F5 ')C,9;3+)


K,)0 /#( ,12A+3&5 .3+ (%+. H#F(+4)5&5 /#( )'97.5 .3+ ,(/,2'+'(%+ .3+ (%+ (1(C,Q%+ /#( $',F*-1(C,Q%+ , /#.#+45&5 .56 $,)06 (:E&5 .,* (,&%)#.,6) /#( .,* -,99#-9#&(#&),E .,*6 36

#-,.79'&)# .,* ((/,E 2,+($(%)#.,6. ?,1(#/0 CA&5 .56 -#8,27+'&56. R9959'-($1A&'(6 .3+

(%+ )' .,+ F'+(&.0 . R+.(-((/76 #-,/1;&'(6 .,* F'+(&.0 . ?'97.5 '-(9'2)7+3+ ,(/,2'+'(%+ (%+. ?'97.5 .3+ /9(+(/%+ '/$59%&'3+ ((/%+ 9,()%F'3+ , .14-,( #+;<+'*&56 .3+ (%+ /#( $(A2+3&56 .3+ ((/%+ ),9E+&'3+ , /#8%6 /#( .14-,( -1495B56 /#( #+.()'.%-(&56 .56 ((/06

)49*+&56. I &5)#&;# .3+ #+#&*+$*#&)7+3+ (%+ &.5 )'.#:1#&.(/0 (#.1(/0 (2,+($(#/0 8'1#-';#/#+A-.*F5 ')C,9;3+).

.=?<8HFCJ 7I<:>

• @'+(/76 ($(4.5.'6 .3+ (%+: $,)0 , .#F(+4)5&5 /#.A Baltimore, ((/46 -,99#-9#&(#&)46

• ?,1(#/0 CA&5 .56 -#8,27+'&56

• R9959'-($1A&'(6 (%+-F'+(&.%+. R+.(-((/76 #-,/1;&'(6 .,* F'+(&.0 .• U(/,27+'(# .3+ '1-5.,Q%+ (Ierpesviridae)

• V,; .56 5-#.;.($#6 ((46 .56 5-#.;.($#6 B /#( .56 5-#.;.($#6 C)

• V46 .3+ #+81%-(+3+ 8593)A.3+ (Papillomaviridae)

• P'.1,Q,; (Retroviridae)

• V,; .56 21;-56 (Myxoviridae, Paramyxoviridae)

• V46 .56 -,9(,)*'9;.($#6 (Picornaviridae)

• U( #+#&*+$*#&)7+,( (,; 36 :,1';6 &.5 )'.#:1#&.(/0 (#.1(/0 (2,+($(#/0 8'1#-';#/#+A-.*F5 ')C,9;3+)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

130

EFG6BC:9H=>

!89=OJR8 'AL<:7A<6, L#8520.1(# >(,<5)';#6

-FCAH=<@98 %O@KOFA , J-;/,*1,6 L#8520.1(# ?,1(#/06 R+,&,C(,9,2;#6.


+@HO:>: VUZU@VR 1LNN<ASIA>: K1. J97+5 L#9/A+5 - ?-,*&(A/,* "CG:HFCJ> &@C:>: JZZI" +JR:> & %<J9:> TCG:B8>: 2008ISBN: 960-286-977-1,?GFCJ> ")E&U&1: 16445

+@HO:>: VRHPVLI ?VLPU>VUZU@VR & VUZU@VR 1LNN<AS=@>: V.L . T#-#-#+#2(%.,* & >.

L*1#D,-,E9,*-K#9#Q+# "CG:HFCJ> &@C:>: University Studio Press+JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 , 2004ISBN: 960-12-1007-5,?GFCJ> ")E&U&1: 17328


K(#97F'(6 &., #):(87#.1, , C;+.', , /1(.(/0 &*D0.5&5 )' $(A9,2, /#( &*))'.,<0 .3+ :,(.5.%+ ,

59'/.1,+(/0 -9#.:41)# .,* )#80)#.,6 (e-class), '12#&;'6 -,* &.51;D,+.#( &.5 )'97.5 /#(

#+A9*&5 '-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;#.

2OPBBA EFGABCAO@A>

J995+(/0


U( :,(.5.76 #F(,9,2,E+.#( )' CA&5 .5+ '-;$,&0 .,*6 &' #)'12#&;# -,* C#&;D'.#( &.5 &E2<1,+5 C(C9(,21#:;# /#( C)21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

132

4. P#$('+712'(#

4.1. G*&(/0 P#$('+712'(#

4.1.1. P#$4+(, /#( 8*2#.1(/A .,* -#1A232#: C(,9,2(/76 '-($1A&'(6 &.5 $5)4&(# !2';#

4.2. H'<+5.0 P#$('+712'(#

4.2.1. P#$('+'1246 #-,)';3&5

4.2.2. H14-,( 1#$('+'12%+ $(#&.A&'3+

4.2.3. ?,+A$'6 )7.15&56 1#$('+'12%+ $(#&.A&'3+

4.2.4. T*15+(/76 #+.($1A&'(6

5. R9959'-;$1#&5 R/.(+,C,9;#6 – S956

5.1. G3.,59'/.1(/4 :#(+4)'+,

5.2. G#(+4)'+, Compton

5.3. K;$*)5 27+'&5 5.4. R9959'-;$1#&5 )' :,1.(&)7+# &3)#.;$(#

6. R/.(+,C,9;# =

6.1. G#(+4)'+, -7$5&56

6.2. =#1#/.51(&.(/0 =-#/.(+,C,9;#

6.3. J+'12'(#/4 :A&)# =-#/.(+,C,9;#6

7. K,&()'.1;#

7.1. MA9#),( V,+(&),E

7.2. a99,( .14-,( )7.15&56 R-,11,:,E)'+56 $4&56

8. L#.#+,)0 K4&56 &' V#.1(/76 J:#1),276

8.1. R/.(+,9,2;#

8.2. T*15+(/0 V#.1(/0 – P#$(,:A1)#/# – >(,9,2(/76 '-($1A&'(6

8.3. R/.(+,8'1#-';#

9. U12#+,9,2;#

3. 1+&$%"$- #-E$&3$&4&2$-1

1. R-,114:5&5 R/.(+,C,9;#6 #-4 .5+ S95

1.1. O3)A.(# #

1.2. O3)A.(# C

1.3. G3.4+(# (#/.(+,C,9;# 2)

1.4. "'.14+(#

2. =5)(/76 ?'.#C,976 )'.A #-,114:5&5 V,+.;D,*&#6 R/.(+,C,9;#6 – J9'E8'1'6 P;D'6

3. J-;$1#&5 R/.(+,C,9;#6 &' ?,1(#/4 '-;-'$,. >(,9,2(/76 C9AC'6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

133

3.1. T13.'\+'6

3.2. N+D*)#

3.3. ",*/9'Q+(/A ,F7#

3.4. Z;-5

3.5. !$#.A+81#/'6

4. J-;$1#&5 R/.(+,C,9;#6 &., LE..#1,. >(,9,2(/76 C9AC'6

4.1. L*..#1(/0 ?')C1A+5

4.2. L*..#14-9#&)#

4.3. Z*&,&%)#.#

4.4. ?(.,<4+$1(#

2. ,4$($,"1 "0-#'&2"1

5. J-;$1#&5 R/.(+,C,9;#6 &.,+ -,99#-9#&(#&)4 .,* L*..A1,*.

?'.#99AF'(6

6. J-;$1#&5 R/.(+,C,9;#6 &' V&.,E6 – X12#+# – R+81%-3+

6.1. L9(+(/A OE+$1,)#

6.1.1. R(),-,(5.(/4 OE+$1,),

6.1.2. @#&.1'+.'1(/4 OE+$1,),

6.1.3. OE+$1,), L"O

6.1.4. L#)-E9'6 '-(C;3&56 J1*81%+ R(),&:#(1;3+ 6.2. J-;$1#&5 &' 412#+#

6.2.1. R+#-#1#232(/4 OE&.5)#

6.2.2. Z'):(/4 OE&.5)#

6.2.3. K71)#

6.2.4. U:8#9),;

6.2.5. T+'E),+'6

6.2.6. L#1$(A

6.2.7. c-#1

6.2.8. "':1A

6.2.9. N)C1*,

7. T1%()# – R-%.'1# R-,.'97&)#.# R/.(+,C,9;#6

8. P#$(,'-(&5)A+&'(6 - =13)#.,21#:;#

8.1. J-(&0)#+&5 -'-.($;3+

8.2. J-(&0)#+&5 ?,+,/93+(/%+ R+.(&3)A.3+

8.3. P#$(,:A1)#/# – R-,11,:,E)'+5 K4&5 – C(,9,2(/76 '-($1A&'(6 8.4. L9(+(/76 ':#1),276



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

134

9. J-;$1#&5 R/.(+,C,9;#6 '-; /#/,58%+ 42/3+. R/.(+,8'1#-';# – L9(+(/76 ':#1),276

10. ?,1(#/0 T*15+(/0 V#.1(/0 – PET – L9(+(/76 ':#1),276

11. R/.(+,-1,&.#&;# ",),8'&;# 2(# .(6 #/.(+,C,9;'6.


1. a&/5&5 .3+ :,(.5.%+ /#.^,)A$'6 &., T#+'-(&.5)(#/4 J12#&.01(, T*15+(/06 V#.1(/06. (4 %1'6)

EFG6BC:9H=>

-. ]8BF7JR:LO:> , J-;/,*1,6 L#8525.06 T*15+(/06 V#.1(/06 , H)0)# V#.1(/06 KTM.


+@HO:>: V#.1(/0 G*&(/0 1LNN<ASIA>: d#11A/,6 L ., ?,9*C$A- R8#+#&,-,E9,* J.,

@/,.D#)A+5 -d#11A/,* a., O(,E+.#6 R."CG:HFCJ> &@C:>: University Studio Press+JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 2010ISBN: 978-960-12-1420-7,?GFCJ> ")E&U&1: 17332

+@HO:>: L9(+(/76 J:#1),276 T*15+(/06 V#.1(/06 1LNN<ASIA>: W5&()4-,*9,6 R8#+A&(,6 "CG:HFCJ> &@C:>: BROKEN HILL PUBLISHERS LTD +JR:> & %<J9:> TCG:B8>: R80+# 2004

ISBN: 9789603992448,?GFCJ> ")E&U&1: 13256705


+@HO:>: O5)'(%&'(6 P#$(,C(,9,2;#6

1LNN<ASIA>: R W5&()4-,*9,6 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 2011


K(#97F'(6 &.# C#&(/A 8'315.(/A 87)#.# -,* #+#9E,+.#( -#1#-A+3.

L#.A -'1;-.3&5 , 2;+,+.#( $(#97F'(6 #-4 -1,&/'/95)7+,*6 '-(&.0),+'6 , /#( &*+'12A.'6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

135

2OPBBA EFGABCAO@A>

J995+(/A. L#.A -'1;-.3&5 , 5 &*+(&.%)'+5 '-(-97,+ C(C9(,21#:;# '-()71,*6 '+,.0.3+

)-,1'; +# ';+#( /#( &.# #229(/A.


@1#-.76 'F'.A&'(6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

136

0-#'-,&4&2$-


OH’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) I -#1,*&;#&5 /#( /#.#+45&5 C#&(/%+ '++,(%+ &.5 G#1)#/,9,2;#.

C) I -'1(21#:0 /#( /#.#+45&5 .3+ ),1(#/%+ )5<#+(&)%+ /#( .3+ C#&(/%+ #1<%+ $1A&56

:#1)A/3+.

2) I )'97.5 .3+ ),1(#/%+ )5<#+(&)%+ $1A&56 :#1)A/3+ )7&# #-4 -#1#$';2)#.# :#1)A/3+

-,* '-($1,E+ &' $(A:,1# &*&.0)#.# -.<. +'*1(/4 &E&.5)# , /#1$(#22'(#/4 &E&.5)#.

$) I /#.#+45&5 .3+ C#&(/%+ #1<%+ .56 <5)'(,8'1#-';#6 /#( .,* .14-,* $1A&56

<5)'(,8'1#-'*.(/%+ -#1#24+.3+.

') I .#*.,-,;5&5 +73+ ),1(#/%+ &.4<3+ &.5+ #+A-.*F5 +73+ :#1)A/3+.


• J(&#2320 &.5 G#1)#/,9,2;# – >#&(/76 #1<76 M'1#-'*.(/06

• R1<76 :#1)#/,/(+5.(/06 (,$,; <,1025&56 , )5<#+(&),; #-,114:5&56 /#( /#.#+,)06 ,

)'.#C,9(&)46 /#( #-7//1(&5 :#1)A/3+)

• R1<76 :#1)#/,$*+#)(/06 ()5<#+(&),; $1A&'(6 :#1)A/3+ , #9959'-($1A&'(6 :#1)A/3+

- *-,$,<73+)

• G#1)#/,2'+'.(/0 - G#1)#/,2,+($(3)#.(/0

• GA1)#/# -,* $1,*+ &., R*.4+,), "'*1(/4 OE&.5)#

•

GA1)#/# -,*

$1,*+

&.,

L'+.1(/4

"'*1(/4

OE&.5)#

• GA1)#/# -,* $1,*+ &., L#1$(#22'(#/4 OE&.5)#

• R1<76 <5)'(,8'1#-';#6

• ?(/1,C(#/A <5)'(,8'1#-'*.(/A :A1)#/#

• L#1/(+(/A <5)'(,8'1#-'*.(/A :A1)#/#

• R+A-.*F5 +73+ :#1)A/3+: O.A$(# C#&(/06 71'*+#6 /#( /9(+(/06 $,/()#&;#6

EFG6BC:9H=>

-. !ARR6 , J-;/,*1,6 L#8520.1(# ?,1(#/06 G*&(,9,2;#6 - G#1)#/,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

137


+@HO:>: G#1)#/,9,2;#

1LNN<ASIA>: Harvey R.A., Champe P.C."CG:HFCJ> &@C:>: T#1(&(A+,6 R.J.+JR:> & %<J9:> TCG:B8>: R80+# , 35 7/$./2007ISBN: 978-960-394-502-4,?GFCJ> ")E&U&1: 41693

+@HO:>: G#1)#/,9,2;# 1LNN<ASIA>: Rang H.P., Dale M.M., Ritter J.M., Moore P.K."CG:HFCJ> &@C:>: T#1(&(A+,6 R.J.+JR:> & %<J9:> TCG:B8>: Athens, 5 th edition/2007ISBN: 978-960-394-429-4

,?GFCJ> ")E&U&1: 41692


K(#97F'(6 /#( &5)'(%&'(6 .,* )#80)#.,6 $(#.;8'+.#( &.5+ (&.,&'9;$#:

https://eclass.duth.gr/eclass/courses/ALEX01132/


K(#97F'(6 (59'/.1,+(/0 -9#.:41)# e-class), /#8,$52,E)'+5 )'97.5 '-(&.5),+(/%+ A1813+ /#(

-#1,*&;#&5 '12#&(%+

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 .3+ :,(.5.%+ 2;+'.#( &*+#1.0&'( .3+ '-($4&'%+ .,*6 &.(6 -#1,*&(A&'(6 '-(&.5),+(/%+ -'1(,$(/%+ (30%) /#( &.(6 .'9(/76 21#-.76 'F'.A&'(6 .,* )#80)#.,6 (70%).



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

138

%/'$,"1 "(*1"$1 +/1 ,-./'"#$(/1 ]*/1


W’ J 1 1 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) I '-#:0 .3+ :,(.5.%+ )' <5)(/76 ,*&;'6 -,* C1;&/,*)' 0 '1<4)#&.' &' '-#:0 &.5+ /#85)'1(+0 )#6 D30 )' 7):#&5 &.5 &<7&5 .,*6 )' .5 C(,9,2;#.

C) I '-#:0 .3+ :,(.5.%+ )' <5)(/76 ,*&;'6 -,* C1;&/,*)' &' +7# *9(/A , /*1;36 *9(/A

+#+,.'<+,9,2;#6 -,* <15&(),-,(,E+.#( 49, /#( -'1(&&4.'1, &.5+ /#85)'1(+0 D30 , #99A /#(

&' C(,Q#.1(/76 ':#1),276.

2) "# )-,17&,*+ +# 21AB,*+ 7+# ,9,/9513)7+, /';)'+, &E):3+# )' .(6 '-(&.5),+(/76

'-(.#276 , <15&(),-,(%+.#6 /#( '-(&5)#;+,+.#6 .5 C(C9(,21#:;# , +# -#1,*&(A&,*+ &' /,(+4

.5+ '12#&;# .,*6 /#( +# #-#+.0&,*+ &' '13.0&'(6.


M'315.(/4 )71,6

• T,9*)'10

• R-,11*-#+.(/A

• H14:()#

• GA1)#/#

• ?7.#99#

•

=13&.(/76- =1%)#.# • T'1(C#99,+.(/,; PE-,(

• L#E&()#

• !9(/A +#+,.'<+,9,2;#6 )' ':#1),276 &.5 *2';#

• !9(/A +#+,.'<+,9,2;#6 )' ':#1),276 &.5+ /#85)'1(+0 D30

• !9(/A +#+,.'<+,9,2;#6 /#( .,F(/4.5.#

• !9(/A +#+,.'<+,9,2;#6 /#( -'1(CA99,+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

139

EFG6BC:9H=>

,. %. 0LOACHAC@G:L , R+#-951%.1(# L#8520.1(# =5)';#6 U12#+(/%+ J+%&'3+.


+@HO:>: =5)';# /#( L#85)'1(+0 W30 1LNN<ASIA>: >A1C,2956 R+#&.A&(,6 "CG:HFCJ> &@C:>: R9. ?#)A956 & O(# +JR:> & %<J9:> TCG:B8>: 15 N/$,&5 2006ISBN: 960-7778-91- = ,?GFCJ> ")E&U&1: 15999

+@HO:>: H# '.'1,/*/9(/A &.5 D30 /#( .5+ /,(+3+;# 1LNN<ASIA>: Pozharskii Alexander F."CG:HFCJ> &@C:>: J/$,.(/46 U;/,6 R. HD(49# & !(,; R.J.+JR:> & %<J9:> TCG:B8>: 15 N/$,&5 2004ISBN: 960-418-038- = ,?GFCJ> ")E&U&1: 18548935

2OPBBA EFGABCAO@A>

J995+(/0


K(#97F'(6 /#( &')(+A1(#.


T1,:,1(/76 /#( @1#-.76 T#1,*&(A&'(6 J12#&(%+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

140

2"("+$,/ "!$,+/+*( -1."("$*( ,-$ '"+-0#-1+$,/ $-+#$,/


W’ J 2 0 2 2


R*.4 ., )A85)# #-,.'9'; .5 CA&5 2(# .5+ /#.#+45&5 .56 &<7&56 )'.#FE .56 2'+'.(/06 , .56

),1(#/06 C(,9,2;#6 , .56 #+#-.*F(#/06 C(,9,2;#6 , .56 C(,-951,:,1(/06 /#( .56 (#.1(/06.

R+#-.E&&'( .(6 &*+$7&'(6 )'.#FE .56 C#&(/06 /#( .56 /9(+(/06 71'*+#6 )' .5+ -1,,-.(/0

.56 ':#1),206 .56 &' #&8'+';6. O.# -9#;&(# .,* )#80)#.,6 )'.#:1AD,*)' .5+ /9(+(/0

'(/4+# &., '-;-'$, .,* 2,+($;,* /#( .56 2,+($(3)#.(/06 /#( #+#9E,*)' &E2<1,+'6

8'1#-'*.(/76 -1,&722(&'(6.


1. 2=9=HFCD ,A<C@9:L

>(,9,2;# .,* /#1/(+(/,E /*..A1,*-G*&(/0 J-(9,20 /#( 5 'F79(F5 .,* /#1/;+,*- «J8(&)46»

(addiction) .3+ /#1/(+(/%+ /*..A13+ &.# ,2/,2,+;$(#->9#&.,//E..#1# /#( ,2/,27+'&5 -

J-(2'+'.(/0 /#1/;+,*-H, -1,:;9 '/:1#&56 2,+($;3+ .3+ ,2/3+ )' .5 <10&5 )(/1,&*&.,(<(3+

(microarrays)->(,9,2(/,; K';/.'6 (Biomarkers) &.5+ ,2/,9,2;#- T1,2+3&5 ,K(#2+3&5 /#( 8'1#-';#-

@,+($(3)#.(/0 .,* /#1/;+,*. ?'.#:1#&.(/0 '1'*+# /#( 8'1#-';#.

2. 2=9=HFCD (=L<:=CSLOFBHFCP9 (JB?9

>(,9,2;# .,* +'*1,'/:*9(&.(/,E /*..A1,*- ->9#&.,//E..#1# /#( #+#2'++5.(/0 8'1#-'A 2(#

.(6 +4&,*6 .,* TA1/(+&,+ /#( R9D<A()'1 – J-(2'+'.(/0 &.(6 '/:*9(&./76 #&87+'('6.

G.(A<+,+.#6 ., -1,:;9 .56 2,+($(#/06 7/:1#&56 &.(6 '/:*9(&.(/76 #&87+'('6- >(,9,2(/,;

K';/.'6 &.(6 '/:*9(&.(/76 #&87+'('6 2(# . 5+ '+;&<*&5 .56 $(A2+3&56 , .56 -142+3&56 /#(

.56 1E8)(&56 'F#.,)(/'*)7+56 8'1#-';#6 – @,+($(3)#.(/0 '/:*9(&.(/%+ $(#.#1#<%+ –

)'.#:1#&.(/0 71'*+# &.(6 '/:*9(&.(/76 #&87+'('6 /#( #+#/A9*B5 :#1)A/3+ ,3. '=HAS<ABHFCD "RFBHD78

H( '(+#( , , &/,-46 .56 , 2(#.( <1'(#D'.#( /#( -,(# 5 .17<,*&# /#.#&.#&5 .56 M'.#:1#&.(/06

V#.1(/06 (Translational Medicine)- JF#.,)(/'*)7+5 V#.1(/0 (Personalize Medicine)

EFG6BC:LBA

$?699A 'A<:LO6C:L , L#8520.1(# @'+'.(/06


OE<1,+'6 '-(&/,-0&'(6 /#( -13.4.*-'6 $5),&('E&'(6 &.# $($A&/,+.# '-(&.5),+(/A -'$;#



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

141

2OPBBA EFGABCAO@A>

J995+(/A

EFGACHFCI> – 'AM8BFACI> 'IM:G:F K(#97F'(6


T#1,*&(A&'(6 &E2<1,+56 C(C9(,21#:;#6 /#( 21#-.0 '12#&;#.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

142

'&#$-,/ 3$&4&2$- 0)+*(


W’ J 2 0 2 2


?,1:,9,2;# , #+#.,);# 1;D#6 , C9#&.,E , :E99,* /#( A+8,*6. ?5<#+(&),; -14&95B56 /#(

)'.#:,1A6 (4+.3+ /#( C(,),1;3+. R+412#+5 817B5 . REF5&5 . R+A-.*F5 . G3.,&E+8'&5 .

G3.,#+#-+,0 . ?'.#C,9(&)46 #D%.,*. G*.4<13)#. L(1/#$(/,; 1*8),;.

!=<F=KJ7=9: H:L 7AMD7AH:> (Syllabus):

?,1(#/0 C(,9,2;# .,* :3.,&*+8'.(/,E )5<#+(&),E.

G3.,#+A-.*F5 .,* :3.,&*+8'.(/,E )5<#+(&),E.

G3.,-1,&#1),20 – :3.,#+#&.,90 .

?,1(#/0 #+.;$1#&5 .,* :*.,E &' $*&)'+0 -'1(CA99,+.#.

G,1';6 /#( $(#2,+($(#/A :*.A. V&.,/#99(712'(# – L*..#1,/#99(712'(#.

H'<+,9,2;# -13.,-9#&.%+ , /#99,27+'&5 , &3)#.(/0 ')C1*,27+'&5 , #+#27++5&5 :*.%+.

I9'/.1,-413&5 .

@,+($(#/0 &.4<'*&5 - J-(9,20 2'+'.(/A .1,-,-,(5)7+3+ :*.%+. K5)(,*12;# :*.%+

#+8'/.(/%+ &.# D(D#+(,/.4+#.

G*.A #+8'/.(/A &.# 7+.,)#.

G*.A #+8'/.(/A &.,*6 (,E6 , C#/.01(# /#( )E/5.'6.

J$%$()# ')C49(#.

K(#<';1(&5 .3+ +73+ /#(+,.,)(%+-.'<+,9,2(%+. >(,.'<+,9,2;# /#( -'1(CA99,+.

>(,#&:A9'(#.

EFG6BC?9


+@HO:>: >(,.'<+,9,2;# G*.%+ 1LNN<ASIA>: T. =#.D4-,*9,6 "CG:HFCJ> &@C:>: JLKUOJVO T. =. TRO=RZVKIO +JR:> & %<J9:> TCG:B8>: R80+# 15 7/$./2006

ISBN: 9789603994046,?GFCJ> ")E&U&1: 13256404



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

143


K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class.


JF7.#&5 21#-.0 &., .79,6 .,* 'F#µ0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

144

'/%-($1'&$ &2,&2"("1/1


W’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) ,( :,(.5.76 +# /#.#+,0&,*+ #1<(/A /#( +# 'µC#8E+,*+ &.5 &*+7<'(# &.(6 C#&(/76 #1<76

/#( 7++,('6 .56 ,2/,27+'&56

C) 5 -#1,*&;#&5 .3+ +' 4.'13+ $'$,µ7+3+ -,* #:,1,E+ &.,*6 -(, &5 µ#+.(/,E6 µ,1(#/,E6

µ5<#+(&µ,E6 -,* &*+$7,+.#( µ' .(6 $(#.#1#<76 .,* /*..#1(/,E /E/9,* , .56 #-4-.3&56 ,.56 #22'(,27+'&56 , /#( .56 µ'.A&.#&56.

2) 5 2+%&5 /#( 5 '+5 µ713&5 .3+ :,(.5.%+ 2(# .(6 .'9'*.#;'6 '-(&.5 µ,+(/76 'F'9;F'(6

&.5 ?,1(#/0 K(A2+3&5 /#( M'1#-';# .,* L#1/;+,*.


M'315.(/4 )71,6

H, µA85 µ# #-,.'9';.#( #-4 10 '+4.5.'6:

J+4.5.# 1. J(&#2320 – J-($5 µ(,9,2;# .,* L#1/;+,*

J+4.5.# 2. U2/,2,+;$(# /#( U2/,/#.#&.#9.(/A 2,+;$(#

J+4.5.# 3. R-,11E8µ(&5 .,* /*..#1(/,E /E/9,* /#( L#1/;+,6

J+4.5.# 4. !-,F;# – R22'(,27+'&5

J+4.5.# 5. ?'.A&.#&5

J+4.5.# 6. UF'($3.(/4 &.1'6 /#( /#1/(+,27+'&5

J+4.5.# 7. M'1#-'*.(/76 -1,&'22;&'(6 &.,+ /#1/;+, J+4.5.# 8. ?,1(#/0 K(A2+3&5

J+4.5.# 9. ?(/1,&*&.,(<;'6 2,+($;3+ /#( /#1/;+,6

J+4.5.# 10. O.,<'*µ7+'6 8'1#-';'6

EFG6BC:9H=>

E<. -OI58> 2AO698> , J-. L#8525.06 ?,1(#/06 >(,9,2;#6

E<. !=<FBHI<A !6BK:L , J-. L#8520.1(# @'+'.(/06

E<. -NOA[A !ARR6 , J-. L#8520.1(# G*&(,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

145


+@HO:>: >(,9,2;# .,* L#1/;+,* 1LNN<ASIA>: L(.1A/5 J*8*);# ,H1,E2/,6 L3+&.#+.;+,6 "CG:HFCJ> &@C:>: JLKUOJVO T. =. TRO=RZVKIO

+JR:> & %<J9:> TCG:B8>: R80+# 15 7/$./2006ISBN: 9789603994046,?GFCJ> ")E&U&1: 13256404

+@HO:>: R"RO!"K!RO?J"U DNA1LNN<ASIA>: James D. Watson"CG:HFCJ> &@C:>: RLRKI?R_LJO JLKUOJVO V. ?TROKPR & OVR +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 35 7/$./2007ISBN: 9789608841253,?GFCJ> ")E&U&1: 2625


K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class.


JF7.#&5 21#-.0 &., .79,6 .,* 'F#µ0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

146

'&#$-,/ 3$&+"%(&4&2$- ,-$ E$-+#&0/


W’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

I /#.#+45&5 #-4 .,*6 :,(.5.76 .3+ C#&(/%+ #1<%+ -,* $(7-,*+ .5+ '-(&.0 µ5 .56 ?,1(#/06

>(,.'<+,9,2;#6 /#( .56 K(#.1,:06. Y6 .'<+,9,2;# #(<µ06 , 5 >(,.'<+,9,2;# &0 µ'1# 'µ-97/'.#(

&<'$4+ &' 49'6 .(6 $(#$(/#&;'6 -#1#23206 /#( C'9.;3&56 .56 -,(4.5.#6 .3+ .1,:;µ3+ ,#+A-.*F56 .56 2'312;#6 , -#1#23206 +73+ -1,Q4+.3+ , C'9.;3&5 .56 *2';#6 /#( -1,&.#&;#6

.,* /#.#+#93.0 . O*+$*AD,+.#6 2+%&'(6 ?,1(#/06 >(,9,2;#6 /#( >(,.'<+,9,2;#6 , K(#.1,:06 ,

?(/1,C(,9,2;#6 /#( =5 µ';#6 /#( $;+,+.#6 ($(#;.'15 &5 µ#&;# &.(6 -1,,-.(/76 /#( .(6

':#1µ,276 .3+ µ,1(#/%+ .'<+(/%+ , .3+ '+DEµ3+ /#( .3+ µ(/1,,12#+(&µ%+ , ., µA85 µ#

&<'$(A&.5/' 7.&( %&.' +# /#9E-.'( .(6 #+A2/'6 .3+ :,(.5.%+ 2(# '+46 '*1E.'1,* :A&µ#.,6

2+%&'3+.

!=<F=KJ7=9: H:L

7AMD7AH:>

H, µA85 µ# ?,1(#/0 >(,.'<+,9,2;# /#( K(#.1,:0 8# #-,.'9';.#( #-4 10 '+4.5.'6:

J"UHIHR 1: J(&#2320 – T'1(21#:0 .,* µ#80 µ#.,6.

J"UHIHR 2: ?,1(#/76 .'<+(/76 µ' ':#1µ,20 &.5 >(,.'<+,9,2;# .1,:;µ3+ – TTGE, DDGE, Multiplex

PCR, Real-Time PCR.

J"UHIHR 3: @'+'.(/0 .1,-,-,;5&5 :*.%+ /#( µ(/1,,12#+(&µ%+ – @'+'.(/A .1,-,-,(5 µ7+#

.14:(µ# – >(,58(/A D5.0 µ#.#.

J"UHIHR 4: Z'(.,*12(/A .14:(µ#: T1,C(,.(/A , T1'C(,.(/A , O*µC(3.(/A.

J"UHIHR 5: H14:(µ# µ' :#1µ#/'*.(/0 $1A&5 (Nutraceuticals) -J$%$(µ# 'µC49(#.J"UHIHR 6: ?,1(#/76 .'<+(/76 2(# .5+ #+;<+'*&5 +,8';#6 &.# .14:(µ#.

J"UHIHR 7: H, /4//(+, /1#&; , 5 1'&C'1#.1495 /#( ., 2#99(/4 -#1A$,F,.

J"UHIHR 8: >(,.'<+,9,2(/A -1,Q4+.# *B5906 $(#.1,:(/06 #F;#6.

J"UHIHR 9: G*.(/A '/<*9;&µ#.# µ' #+.(,F'($3.(/0 – #+.(/#1/(+(/0 $1A&5 .

J"UHIHR 10: ?,1(#/76 #9959'-($1A&'(6 /#( 2'*&(2+3&;#.

EFG6BC:9H=>

E<. -OI58> 2AO698>, J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6

E<. $?6998> ,:L<C:LH6>, J-;/,*1,6 L#8525.06 J:#1),&)7+56 >(,.'<+,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

147


+@HO:>: K(#.1,:0 /#( =5)';# H1,:;)3+ 1LNN<ASIA>: L . @#9#+,-,E9,* , @. W#)-'.A/56 , M.

?#*10 ->#C#2(A++5 , A. O(A:#/# "CG:HFCJ> &@C:>: J/$4&'(6 O.#),E95 +JR:> & %<J9:> TCG:B8>: 15 7/$./2007ISBN: 978-960-351-694-1,?GFCJ> ")E&U&1: 12497092

+@HO:>: >(,.'<+,9,2;# 1LNN<ASIA>: L*1(#/;$56 K5)0.1(,6 "CG:HFCJ> &@C:>: W0.5 T'9#2;# & O(# U.J.+JR:> & %<J9:> TCG:B8>: 25 7/$./2000ISBN: 9604315951,?GFCJ> ")E&U&1: 11133


K(#97F'(6 #-4 #µ:(8'A.1,* , <10&5 e-class.


1. @1#-.0 #F(,9425&5 2. O*221#:0 '12#&(%+

3. T1,:,1(/0 -#1,*&;#&5 '12#&(%+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

148

-#%"1 E$-%"$#$1/1 ]**( "#2-1+/#$&)


W’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) +# '(&A2'( ., :,(.5.0 &.(6 C#&(/76 #1<76 .56 J-(&.0)56 .3+ W%3+ J12#&.51;,* ,

C) +# -#17<'( &., :,(.5.0 2'+(/76 -951,:,1;'6 &<'.(/A )' .5 $(#<';1(&5 );#6 '2/#.A&.#&56

'/.1,:06 D%3+ '12#&.51;,* ,

2) +# -#17<'( &., :,(.5.0 '($(/76 -951,:,1;'6 &<'.(/A )' .5 C(,9,2;# , .5+ '/.1,:0 , .5+

#+#(&85&;# , .5+ '*8#+#&;# /#( )5 <'(1,*12(/,E6 <'(1(&),E6 $(#:413+ '($%+ D%3+

'12#&.51;,*.


.=?<8HFCJ 7I<:>

2=9FCJ 'I<:>

• I <10&5 .3+ D%3+ &.5 C(,Q#.1(/0 71'*+#

• L%$(/#6 58(/06 $',+.,9,2;#6 .56 <10&56 .3+ D%3+ &' -'(1#)#.(&),E6

• J+#99#/.(/'6 )78,$,(

• ",),8'&;#

• >#&(/76 #1<76 '/.1,:06

• ?78,$,( <,1025&56 ,*&(%+

• ?78,$,( &*99,206 &3)#.(/%+ *21%+

• R+#(&85&;# • R+.()'.%-(&5 .,* -4+,* /#( .56 .#9#(-31;#6

• J*8#+#&;#

• N9'2<,6 .56 *2';#6 .3+ D%3+ '12#&.51;,*

• ?'8,$,9,2;# 'F7.#&56 .3+ D%3+

• W3#+813-,+4&,(

"FGFCJ 'I<:>

• L,*+'Z(



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

149

• ?*6

• J-;)*6

• =A)&.'1 , (+$(/4 <,(1;$(,

• O#1/,:A2#

• U-95:41#

J-($';F'(6 &' D3+.#+A -'(1#)#.4D3# (<'(1(&),; , &*2/1A.5&5 , <,1025&5 ,*&(%+ , #(),95B;# ,

'*8#+#&;# , #+#.,);#): /,*+79( , )*6 , '-;)*6

EFG6BC?9

!IH<:> )W8O69H8>, J-;/,*1,6 L#8525.06 T'(1#)#.(/06 ='(1,*12(/06 "0 ?"L$D8 D28 7($M0.'(D8

2B1 ;0('$"$2&@=B1 , H)0)# V#.1(/06 K5),/1;.'(,* T#+'-(&.5);,* M1A/56


+@HO:>: R1<76 K(#<';1(&56 W%3+ J12#&.51;,* 1LNN<ASIA>: T7.1,6 !B59A+.56 "CG:HFCJ> &@C:>: P,.4+.# +JR:> & %<J9:> TCG:B8>: M'&&#9,+;/5 2011ISBN: 978-960-6894-20-6,?GFCJ> ")E&U&1: 127429


K(#97F'(6 , -#1,*&(A&'(6 Power Point, -1,C,976 video, '-($';F'(6 &' D3+.#+A -'(1#)#.4D3# )'

&*))'.,<0 .3+ :,(.5.%+.

2OPBBA EFGABCAO@A>

J995+(/0


T1,:,1(/76 'F'.A&'(6 , -#1,*&;#&5 '12#&(%+ , -14,$,(



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

150

1+&$%"$- 0-#'-,")+$,/1 %/'"$-1 ,-$ %/'"$-1 0)1$,*(

!#&^&(+*(


W’ J 2 0 2 2


H, 40% .3+ :#1)A/3+ -,* <15&(),-,(,E+.#( &0)'1# -1,71<,+.#( 0 -#1A2,+.#( #-4 :*&(/A

-1,Q4+.#. O' ,1(&)7+# -'$;# 8'1#-';#6 , 4-36 , /#1/;+,6 /#( ,( C#/.51(#/76 9,()%F'(6 , .#

-,&,&.A &*))'.,<06 .3+ :*&(/%+ -1,Q4+.3+ ';+#( *B594.'1# /#( #-4 75%. H# :*&(/A

-1,Q4+.# ';+#( $'*.'1,2'+';6 )'.#C,9;.'6 , ,( ,-,;,( '-(.'9,E+ &5)#+.(/76 9'(.,*12;'6

&.,*6 ,12#+(&),E6 ,( ,-,;,( .# -#1A2,*+. R-,.'9,E+ $' , 7+# -,9E &-,*$#;, '12#9';, .56

C(,9,2(/06 <5)';#6 /#( .56 ),1(#/06 C(,9,2;#6 )' ., ,-,;, )-,1,E+ +# #+#/#9*:8,E+

C(,9,2(/A ),+,-A.(# /#( -13.'\+'6 &.4<,( -,* &<'.;D,+.#( )' #&87+'('6.

U( &.4<,( .,* )#80)#.,6 ';+#(:

#) I 2+%&5 .3+ /*1(4.'13+ /#.52,1(%+ .3+ $'*.'1,2'+%+ )'.#C,9(.%+-:*&(/%+ -1,Q4+.3+

(#9/#9,'($0 , .'1-'+,'($0 , :9#C,+,'($0 , 9(-;$(# , )#/1,9;$(# , &A/<#1# /#)

C) I 2+%&5 .,* .14-,* C(,&E+8'&06 .,*6.2) I 2+%&5 .3+ C(,9,2(/%+ .,*6 $1A&'3+ /#( ,( &<7&'(6 $,)06 /#( $1A&56


.=?<8HFCJ 7I<:>

• T1,&.#29#+$;+'6 , 81,)C,FA+(# , 9'*/,.1(7+(# , #13)#.(/A -,9*/'.;$(#-C(,&E+8'&5 /#(

C(,9,2(/76 $1A&'(6

• G#(+*9,-1,-#+,'($0 , /,*)#1;+'6 , /(+4+'6 , :9#C,+,'($0 -C(,&E+8'&5 /#( C(,9,2(/76

$1A&'(6 • H'1-'+,'($0 /#( &.'1,'($0 -C(,&E+8'&5 /#( C(,9,2(/76 $1A&'(6

• R9/#9,'($0 -C(,&E+8'&5 /#( C(,9,2(/76 $1A&'(6

• T'-.;$(# , -13.'\+'6 /#( A99# -#1A232# #)(+,F73+-C(,&E+8'&5 /#( C(,9,2(/76

$1A&'(6

• OA/<#1#-C(,&E+8'&5 /#( C(,9,2(/76 $1A&'(6

• G*&(/A -1,Q4+.# )' #+.(/#1/(+(/0 $1A&5 , &<7&'(6 $,)06 /#( $1A&56

• G*&(/A -1,Q4+.# )' #+.()(/1,C(#/0 /#( #+.(C#/.51(#/0 $1A&5 , &<7&'(6 $,)06 /#(

$1A&56

• M#9A&&(# :*&(/A -1,Q4+.#



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

152

$1+&4&2$-


OH’ J 2 0 2 2


R+.(/';)'+, .56 V&.,9,2;#6 ';+#( 5 )'97.5 .56 *:06 .,* C(,9,2(/,E *9(/,E /#( .3+ .14-3+ )'

.,*6 ,-,;,*6 .# '-()71,*6 &.,(<';# .,* &<'.;D,+.#( )'.#FE .,*6 $,)(/A /#( 9'(.,*12(/A.

R1<(/A , &.5+ '(&#2320 .,* )#80)#.,6 2;+'.#( #+#:,1A &.5 $,)0 /#( .5 9'(.,*12;# .,*

/*..A1,* , /#8%6 /#( &.5+ /*..#1(/0 $(#;1'&5 . O.5 &*+7<'(# , #+#9E,+.#( C#&(/A ';$5 (&.%+

4-36 ';+#(: , &*+$'.(/46 (&.46 , , '-(859(#/46 , , )*Q/46 /#( , +'*1(/46 (&.46. H79,6 , ., )A85)#

'&.(AD'.#( &' &*&.0)#.# ,12A+3+ .# ,-,;# ';+#( .# 'F06: ., /*/9,:,1(/4 , ., #+,&,-,(5.(/4 ,

., #+#-+'*&.(/4 &E&.5)# , ., $71)# , 5 2#&.1'+.'1(/0 ,$46 , ,( '+$,/1(+';6 #$7+'6 , ., /'+.1(/4

+'*1(/4 &E&.5)# , ., #+#-#1#232(/4 &E&.5)# .,* A11'+,6 /#( ., #+#-#1#232(/4 &E&.5)# .,*

809',6.


• ?#/1,&/,-(/0 #+#.,);# /#( '($(/76 .'<+(/76 &.5+ V&.,9,2;# (V&.,<5)';# ,L*..#1,<5)';# , R+,&,Q&.,<5)';# /#( A99'6 ?,1(#/76 .'<+(/76).

• LE..#1,.

• J-(859(#/46 V&.46.

• O*+$'.(/46 V&.46.

• "'*1(/4 OE&.5)#.

• ?*Q/4 OE&.5)#.

• L*/9,:,1(/4 OE&.5)#.

• T'-.(/4 OE&.5)#.

• R+#-+'*&.(/4 OE&.5)#.

• K71)#.

• @'++5.(/4 OE&.5)# .,* A11'+,6 /#( 809',6 .

• T9#/,E+.#6.

• O*22'+';6 #+3)#9;'6.

EFG6BC:LBA

'-#$- 4-'!#&!&)4&) , J-;/,*1,6 L#8520.1(# V&.,9,2;#6-J)C1*,9,2;#6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

153


+@HO:>: VOHUZU@VA1LNN<ASIA>:"CG:HFCJ> &@C:>: PUHU"HR

+JR:> & %<J9:> TCG:B8>: MJOORZU"VLI 2011ISBN: 978-960-6894-28-2,?GFCJ> ")E&U&1:7950625


K(#97F'(6 /#( ,)#$(/76 &*D5.0&'(6.

2OPBBA EFGABCAO@A>

J995+(/0


H'9(/76 -1,:,1(/76 'F'.A&'(6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

154

"$E$,- ."'-+- )!&4&2$1+$,/1 3$&4&2$-1


W’ J 2 0 2 2



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

155

"$E$,- ."'-+- 3$&!4/#&0&#$,/1


OH’ J 2 0 2 2


>(,-951,:,1(/06 '+$4.'1#: Perl


.=?<8HFCJ 7I<:>

Perl: 5 /*1;#1<5 29%&&# 2(# µ(/176 (/#( µ'1(/76 :,176 4<( /#( .4&, µ(/176) ':#1µ,276

>(,-951,:,1(/06. @'+(/A <#1#/.51(&.(/A 29%&&#6 , O*221#:0 /#( '/.79'&5 -1,21#µµA.3+ , K,µ0

-1,21#µµA.3+: ., -1%., -1421#µµ# &' Perl, HE-,( µ'.#C95.%+ : scalars, U( $E, -1%.'6 '+.,976 :

for, while, T1#/.(/0 A&/5&5 15 , HE-,( µ'.#C95.%+ : arrays, J+.,976: foreach, sort, T,9*$(A&.#.,(

-;+#/'6 (2D & 3D), L#8('13µ7+5 ';&,$,6: <STDIN>, J+.,90 split, T1#/.(/0 A&/5&5 25 ,

L#8('13µ7+5 ';&,$,6: #99#20 .,* .14-,* #+A2+3&56 , J;&,$,6/7F,$,6 #-4 #1<';# , HE-,(

µ'.#C95.%+ : hash arrays, T1#/.(/0 A&/5&5 35 , O*+#1.0&'(6 /#( -#1Aµ'.1,( , J-#+A95B5 .56

µ7<1( .%1# E956 , T1#/.(/0 A&/5&5 45 , Regular expressions, T1#/.(/0 A&/5&5 55 , J:#1µ,20 : 7+#

-1421#µµ# &' perl ., ,-,;, 8# C1;&/'( /#( 8# .*-%+'( .5+ µ'2#9*.71,* µ0/,*6 /,(+0

*-#/,9,*8;# µ;#6 ,µA$#6 #9959,*<(%+ , T1#/.(/0 A&/5&5 65 .


JP@ROHIPVRLI ROLIOI 15 , 1 YPR

• R+A9*&5 .56 &*+A1.5&56 1 = f(x,y) = [ 10.0 - sqrt(x e+ye) ] cos[ sqrt(x e+ye) ]

µ' .5 C,08'(# '+46 -1,21Aµµ#.,6 &' perl.


•O*221#:0

'+46

-1,21A

µµ#.,6

-,*

*9,-,(';

.5

µ78,$,

Bradford2(#

.,+

-1,&$(,1(&

µ4 .56

-13.'Q+(/06 &*2/7+.13&56.


• !-,9,2(&µ46 µ,1(#/,E CA1,*6 -13.'\+56 #-4 .5+ -13.,.#20 .56 $,µ0 (#9959,*<;#).


• O*221#:0 '+46 -1,21Aµµ#.,6 &' perl ., ,-,;, 8# $(#CAD'( 7+# PDB #1<';, /#( 8# C1;&/'( .(6

$(#&.A&'(6 (&., ,18,/#+,+(/4 &E&.5 µ# #F4+3+ /#( &' Angstrom) .,* µ,1;,* -,* -'1(7<'( ., PDB

#1<';,.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

156


• O*221#:0 '+46 -1,21Aµµ#.,6 &' perl ., ,-,;, 8#

$(#CAD'( 7+# #1<';, µ' 49'6 .(6 #9959,*<;'6 .56 swissprot, /#( 8# C1;&/'( ., µ0/,6 &'

/#.A9,(-# /#( .,+ /3$(/4 .56 µ'2#9E.'156 &' µ0/,6 #9959,*<;#6.


• O*221#:0 '+46 -1,21Aµµ#.,6 &' perl ., ,-,;, 8# C1;&/'( 49'6 .(6 /,(+76 *-#/,9,*8;'6 µ;#6

,µA$#6 #9959,*<(%+.

EFG6BC:9H=>

(FCJOA:> '. 2OLCJ> , J-;/,*1,6 L#8525.06 (!-,9,2(&.(/0 /#( K,)(/0 >(,9,2;#).


+@HO:>: U$5246 .56 Perl1LNN<ASIA>: Pierce Clinton+JR:> & %<J9:> TCG:B8>: 15 7/$./2005ISBN: 978-960-512-468-7,?GFCJ> ")E&U&1: 12346

+@HO:>: Pro Perl (J9'E8'1, e-book).1LNN<ASIA>: Wainwright, Peter.

+JR:> & %<J9:> TCG:B8>: 2005ISBN: 9781430200147,?GFCJ> ")E&U&1: 170303


KVRZJ]JVO , J]V JP@ROHIPVRLJO ROLIOJVO


JP@ROVJO 30%, J]JHROJVO 70%.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

157

1)2%#&("1 +"%($,"1 ,-$ "0-#'&2"1 1+/ 3$&4&2$- ,)++-#&)


OH’ J 1 1 2 2


J)CA8*+&5 &' &E2<1,+'6 .'<+(/76 ?,1(#/06 L*..#1(/06 >(,9,2;#6 /#( /*1;36 )(/1,&/,-;#6 ,

/#8%6 /#( )'97.5 /#( -#1,*&;#&5 #-4 .,*6 :,(.5.76 .56 &<'.(/06 C(C9(,21#:;#6 )' &.4<,

.5+ &' CA8,6 /#.#+45&5 . 3+ .'<+(/%+ /#( .3+ ':#1),2%+ .,*6. U .14-,6 $($#&/#9;#6 C#&;D'.#( &., problem-based learning ()A85&5 C#&(&)7+5 &' 7+# -14C95)#/87)#), )' &.4<, +#

'-A2'( .5+ #.,)(/0 )'97.5 /#( +# #+#-.EF'( .5+ #+#D0.5&5 -951,:,1(%+ – #-4/.5&5

2+%&'3+ #-4 .,+ /A8' :,(.5.0 F'<31(&.A , )7&# #-4 .5 &*+'12#&;# );#6 )(/106 ,)A$#6.


H, )A85)# 9#)CA+'( <%1# 'C$,)#$(#;36 , F'<31(&.A 2(# .5+ /A8' ,)A$# (6-7 :,(.5.76) ,(

,-,;,( #-,:#&;D,*+ 2(# ., '1%.5)#/87)#/-14C95)# )' ., ,-,;, 8# #&<,958,E+ , )7&# #-4 -1,.'(+4)'+# 87)#.# OE2<1,+3+ H'<+(/%+ (/*1;36 ?(/1,&/,-(/%+) /#( J:#1),2%+ .,*6 &.5

L*..#1(/0 >(,9,2;#. R/,9,*8,E+ &*D5.0&'(6 -A+3 &., '-(9'24)'+, 87)# , #+#-.E&&,+.#(

'-($(3/4)'+,( &.4<,( /#( -1,&'22;&'(6 /#( #/,9,*8'; &*2/7+.13&5 .3+ #-,.'9'&)A.3+ .56

#.,)(/06 )'97.56 .,* /#8'+46 /#( &*D0.5&0 .,*6.

EFG6BC:9H=>

'A<@A ,JSSA, R+#-951%.1(# L#8520.1(# L*..#1(/06 >(,9,2;#6


J-(&.5),+(/A A181# /#( #+#&/,-0&'(6 , &<'.(/76 (&.,&'9;$'6 , &*221A)#.# /#( video

#+#1.%+.#( &.,+ (&.4.,-, .59'/-#;$'*&56 (e-class) .,* )#80)#.,6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

158


H, ),+.79, $($#&/#9;#6 C#&;D'.#( &., -14C95)#/'1%.5)# , (Project-based learning) /#( &.5

8'%15&5 ,.( 5 2+%&5 #-,.*-%+'.#( /#9E.'1# 4.#+ , :,(.5.06 '+'125.(/A .5+ #+#D5.A /#(

.5+ #:,)'(%+'( , -#1A 4.#+ ';+#( -#85.(/46 #-,$7/.56 .56.

2OPBBA EFGABCAO@A>

J995+(/A , &*221A)#.# /#( C(C9(,21#:(/A A181# &.# #229(/A


U .'9(/46 C#8)46 C#&;D'.#( &.5+ &*))'.,<0 .,* :,(.5.0 &.(6 'C$,)#$(#;'6 &*+#+.0&'(6 ,/#8%6 /#( &.5+ #F(,9425&5 .56 '-;.'*F56 .3+ '-($(3/4)'+3+ &.4<3+ /#( .5+ #-4$,&5 .56

,)A$#6 )7&# #-4 .5+ -#1,*&;#&5 .56 '12#&;#6 .,*6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

159

BI&4&2$- 34-1+&,)++-#*( ,-$ -(-2"((/1/1


OH’ J 2 0 2 2


O.4<,( .,* )#80)#.,6 ';+#(:

#) "# #-,/.0&,*+ ,( :,(.5.76 C#&(/76 2+%&'(6 ?,1(#/06 >(,9,2;#6 .56 R+#27++5&56

C) "# )'9'.0&,*+ ,( :,(.5.76 .,*6 C#&(/,E6 ),1(#/,E6 )5<#+(&),E6 -,* $(7-,*+ .5+ C(,9,2;#

.3+ C9#&.,/*..A13+ /#( 2) "# #+.(95:8,E+ ,( :,(.5.76 .(6 $*+#.4.5.'6 #+A-.*F56 /#(+,.4)3+ /*..#1(/%+

8'1#-'(%+ -,* C#&;D,+.#( &.# C9#&.,/E..#1#.


• >(,9,2;# R+#27++5&56 – ?,1(#/,; )5<#+(&),;.

• R-,)4+3&5 – /#99(712'(# – $(#:,1,-,;5&5 C9#&.,/*..A13+.

• I ?,1(#/0 CA&5 .56 -,9*$*+#);#6.

• R-,)4+3&5 , /#99(712'(# /#( $(#:,1,-,;5&5 .3+ ')C1*Q/%+ C9#&.,/*..A13+.

• J:#1),276 .3+ ')C1*Q/%+ C9#&.,/*..A13+.

• @,+($(#/0 8'1#-';# /#( C9#&.,/E..#1#.

• H# C9#&.,/E..#1# '+59;/,* , .# '-#24)'+# C9#&.,/E..#1# /#( ,( ':#1),276 .,*6.

• R1<76 ?5<#+(/06 (&.%+.

• miRNA /#( C9#&.,/E..#1#: , 149,6 .3+ miRNA &.,+ -,99#-9#&(#&)4 , .5 $(#:,1,-,;5&5 /#(

.5 201#+&5 .

• L#1/(+(/A >9#&.,/E..#1# , /*..#1(/0 -,9*$*+#);# , #+8'/.(/4.5.# /#( )'.A&.#&5 .• miRNA /#( /#1/(+(/A C9#&.,/E..#1#: #+A-.*F5 +73+ &.1#.52(/%+ #+.()'.%-(&56.

• N1'*+# /#( 58(/0 – ., -#1A$'(2)# .3+ C9#&.,/*..A13+.

EFG6BC:LBA

'. 2<8N:<@:L , R+#-951%.1(# L#8520.1(# ?,1(#/06 >(,9,2;#6 - R+#-.*F(#/06 >(,9,2;#6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

160


+@HO:>: H# C9#&.(/A /E..#1# 1LNN<ASIA>: @'312A.,6 O- /.#."CG:HFCJ> &@C:>: JLKUOJVO JG!PR +JR:> & %<J9:> TCG:B8>: 15 2008ISBN: 978-960-89692-5-4,?GFCJ> ")E&U&1: 2519.


+@HO:>: >(,9,2;# >9#&.,/*..A13+ /#( R+#27++5&56 T#1,*&(A&'(6 )#80)#.,6

1LNN<ASIA>: ?. @152,1;,* +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2011


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &., )A85)#

<15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, , :,(.5.06 $'+

#-,/.A )4+, 2+%&'(6 , #99A #+#-.E&&'( /#( (/#+4.5.'6 -,* .,* '-(.17-,*+ +# &<'$(AD'(

-'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&, /#( )' .,

$($A&/,+.#.

2OPBBA EFGABCAO@A>

J995+(/0 , -13.4.*-'6 $5),&('E&'(6 /#( A181# #+#&/4-5&56 &.5+ #229(/0 29%&&#.


U( :,(.5.76 #F(,9,2,E+.#( ';.' )' 21#-.76 'F'.A&'(6 .,* )#80)#.,6 &., .79,6 .,*

'F#)0+,* 0 //#( )7&3 '12#&(%+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

161

!"#$#%&' ()*

+,µ-./"0#/1*

2. +3145)*

B$&4&2$- +/1 1)'!"#$0&#-1


OH’ J 2 0 2 2


O.4<,6 .,* )#80)#.,6 ';+#( +# 718,*+ ,( :,(.5.76 &' '-#:0 )' C#&(/A '13.0)#.# .56

>(,9,2;#6 .56 O*)-'1(:,1A6. V$(#;.'15 7):#&5 $;+'.#( &., &<'$(#&)4 /#( &.5 9,2(/0 .3+

-'(1#)A.3+ -,* -'1(21A:,+.#( -1,/'()7+,* +# /#99('1258'; 5 /1(.(/0 -'-(&.5),+(/0 &/7B5 .


V. J(&#232(/A &.,(<';#.

VV. R9.1,*(&.(/0 O*)-'1(:,1A.

VVI. I8,9,2;# – U 149,6 .56 :E&56 /#( .56 #+#.1,:06 (Nature or Nurture Controversy).

IV. M'31;# -#(2+;3+ (Game Theory).

V. H &'F,*#9(/0 &*)-'1(:,1A .56 Drosophila melanogaster .

VI. J-(8'.(/0 &*)-'1(:,1A

EFG6BC:9H=>

2. 1C6XG8> , J-;/,*1,6 L#8525.06 ?,1(#/06 >(,9,2;#6.


+@HO:>: T#1,*&(A&'(6 )#80)#.,6 >(,9,2;# .56 O*)-'1(:,1A6 1LNN<ASIA>: @. O/AC$56 +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2010 –


T1,/'()7+,* +# *-,C,5858'; 5 #+A-.*F5 .56 '-(&.5),+(/06 &/7B56 .,* :,(.5.0 &., )A85)#

<15&(),-,(';.#( 5 &*))'.,<(/0 )78,$,6 $($#&/#9;#6. L#.’ #*.4+ .,+ .14-, , :,(.5.06 $'+

#-,/.A )4+, 2+%&'(6 , #99A #+#-.E&&'( /#( (/#+4.5.'6 -,* .,* '-(.17-,*+ +# &<'$(AD'( -'(1A)#.# '+% .#*.4<1,+# &*+'12AD'.#( .4&, )' .,*6 &*+#$79:,*6 .,* 4&, /#( )' .,



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

162

$($A&/,+.#.

2OPBBA EFGABCAO@A>

J995+(/0 , -13.4.*-'6 $5),&('E&'(6 /#( A181# #+#&/4-5&56 &.5+ #229(/0 29%&&#.


U( :,(.5.76 #F(,9,2,E+.#( ';.' )' 21#-.76 'F'.A&'(6 .,* )#80)#.,6 &., .79,6 .,*

'F#)0+,* 0 //#( )7&3 '12#&(%+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

164

C9#&.,/*..A13+. >(,.1A-'D'6. T#1#2320 ,12A+3+. @,+($(#/0 8 '1#-';#. @'+'.(/46 79'2<,6.

J*2,+(/0 . ?'.#),&<'E&'(6. !-,C,58,E)'+5 #+#-#1#2320 , #+#-#1#232(/0 L93+,-,;5&5 .

T1,2'+'.(/46 /#( -1,'):*.'*.(/46 79'2<,6. H'<+5.0 -#1A.#&5 D306. a)C93&5 . J*8#+#&;#.

T'(1#)#.4D3#. K(/#(%)#.# W%3+. ",),8'.(/4 -9#;&(, (K('8+76 , J*13-#Q/4 , J8+(/4). I

#-,/3$(/,-,;5&5 .,* 2,+($(%)#.,6. @'+'.(/0 .1,-,-,;5&5 (@HU).H'<+5.0 .1,:0 (@'+'.(/A .1,-,-,(5)7+# .14:()#). T#.7+.'6. ",),8'&;#

EFG6BC:9H=>


1. T'1(C#99,+.(/0 J/-#;$'*&5 , , +7,6 -,9(.(&)46 -,* #+#$E'.#( , '-()79'(# R. K.@'3124-,*9,6 , '/$4&'(6 Gutenberg, R80+# 2005

2. >(,58(/0 (!-4.(.9,6: R+#:,1A &.,*6 2'+'.(/,E6 /#( .'<+,9,2(/,E6 +'3.'1(&),E6):

R9#<(%.56 O.#)A.56. J995+(/A @1A))#.# , 2004

EFGACHFCI> CAF 7AM8BFACI> 7IM:G:F:

K(#97F'(6 , '12#&;'6 , ,12A+3&5 $(#8')#.(/%+ &*D5.0&'3+ 942,* /#( #+.;9,2,* , -1,C,976

&<'.(/%+ )' .5+ E95 +.,/()#+.71 /#( '&.(#&)7+,6 $(A9,2,6.

2OPBBA GFGABCAO@A>

J995+(/A

'IM:G:F A5F:OJN8B8>-XAM7:OJN8B8

@1#-.76 'F'.A&'(6 (-,99#-9%+ '-(9,2%+ /#( '13.0&'3+ #+A-.*F56 &' -,&,&.&4 50%) &.,

.79,6 .,* 'F#)0+,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

165

!#-,+$,/ -1,/1/


OH’ J 2 0 2 2



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

166

2"("+$,/ 1+/ E$,-$&1)(/ ,-$ 1+/( $-+#&E$,-1+$,/


OH’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

JF,(/';3&5 .3+ :,(.5.%+ )' .(6 ':#1),276 .56 @'+'.(/06 &.5+ '2/95)#.,9,2;# /#(

(#.1,$(/#&.(/0 .


J(&#2320 /#( -'1(21#:0 .3+ &.4<3+ .,* )#80)#.,6. I <15&()4.5.# .56 @'+'.(/06 &.5+

'2/95)#.,9,2;# /#( .5+ (#.1,$(/#&.(/0 . R9959'-;$1#&5 )' A99'6 '-(&.0)'6 ( +,)(/0 ,

/,(+3+(,9,2;# , #+813-,9,2;# , C(,58(/0 ). T1,,-.(/76 '12#&;#6 &., -'$;,.

@,+($;3)# , <13),&%)#.# , DNA-#+#&/4-5&5 C#&(/%+ #1<%+ 2'+'.(/06.

R+81%-(+5 2'+'.(/0 -,(/(9,),1:;# /#( &.,(<';# :*&(/06 #+813-,9,2;#6.

>(,9,2(/76 -5276 #-,$'(/.(/%+ &.,(<';3+.

>(,9,2(/4 *9(/4 &.,+ .4-, .,* '2/90)#.,6-&*99,20 , &0)#+&5 , $(#<';1(&5 /#( #-,80/'*&5 .

>(,9,2(/4 *9(/4 &' -'1(-.%&'(6 C;#(,* 0 &'F,*#9(/,E '2/90)#.,6.

>(,9,2(/4 *9(/4 &' -'1(-.%&'(6 :*&(/%+ /#.#&.1,:%+ 0 #.*<5)A.3+.

R-,)4+3&5 , -,&,.(/,-,;5&5 /#( <10&5 2'+'.(/,E *9(/,E.

K';/.'6 STR, '+.,-(&)46 , #+A9*&5 /#( <10&5 -,9*),1:(&)%+.

K';/.'6 SNP, '+.,-(&)46 , #+A9*&5 /#( <10&5 -,9*),1:(&)%+ .,*6.

?'97.5 -#.14.5.#6 0 A9956 &*227+'(#6.

K';/.'6 &.5 )'97.5 &*227+'(#6 , )(.,<,+$(#/4 DNA, <13)4&3)# !.

H#*.,-,;5&5 :E9,*.R+A9*&5 /#( -#1,*&;#&5 .3+ 2'+'.(/%+ #-,$';F'3+ , '-'F025&0 .,*6 &., '*1E /,(+4. ",)(/A

/#( 58(/A D5.0)#.#.

@'+'.(/4 *9(/4 D%3+ , )(/1,C;3+ /#( A9956 )5 -#+81%-(+56 -1,79'*&56 &.5+ '2/95)#.,9,2;#.

T(&.,-,;5&5 '12#&.51(%+.

HA&'(6 /( #+#)'+4)'+'6 )'99,+.(/76 'F'9;F'(6 &., -'$;,.

EFG6BC:9H=>

2FA99:QO8> 0ACD> , J-;/,*1,6 L#8525.06 @'+'.(/06 R+81%-,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

167


+@HO:>: @'+'.(/0 V#.1,$(/#&.(/0

1LNN<ASIA>: ?#1;# @'312;,* "CG:HFCJ> &@C:>: J/$4&'(6 T#1(&(A+,* RJ +JR:> & %<J9:> TCG:B8>: 2008

ISBN: 978-960-394-526-0,?GFCJ> ")E&U&1: 41240

+@HO:>: J(&#2320 &.5 K(/#&.(/0 R+813-,9,2;# 1LNN<ASIA>: Steven N. Byers"CG:HFCJ> &@C:>: J/$4&'(6 T#1(&(A+,* RJ +JR:> & %<J9:> TCG:B8>: 2010ISBN: 978-960-394-671-7,?GFCJ> ")E&U&1: 12534156


+@HO:>: O5)'(%&'(6 )#80)#.,6 «@'+'.(/0 &.5 K(/#(,&E+5 /#( V#.1,$(/#&.(/0 »

1LNN<ASIA>: @. G#/06 +JR:> & %<J9:> TCG:B8>: K(#87&()'6 &' 59'/.1,+(/0 ),1:0 , 2012

2OPBBA EFGABCAO@A>

I $($#&/#9;# 2;+'.#( /*1;36 &.# '995+(/A. Y&.4&, 8# <15&(),-,(,E+.#( /#( F'+4293&&'6

-5276 /#( C(C9(,21#:;# /#( 8# D5.';.#( #-4 .,*6 :,(.5.76 5 )'97.5 , /#.#+45&5 /#( <10&5

'-(&.5),+(/%+ A1813+ , /':#9#;3+ C(C9;3+ 0 A9956 C(C9(,21#:;#6 &.5+ #229(/0 29%&&#.


K(#97F'(6 , '12#&;'6. U( -#1#$4&'(6 2;+,+.#( )' .14-, -,* +# '+8#11E+,*+ .5+ '+'120

&*))'.,<0 .3+ :,(.5.%+ &.5 $($#/.(/0 $(#$(/#&;#. O.4<,6 ';+#( );# (&,11,-;# #+A)'&# &.,

$#&/#9,/'+.1(/4 /#( &., )#85.,/'+.1(/4 ),+.79, $($#&/#9;#6.


@1#-.0 'F7.#&5 /#.A .(6 'F'.#&.(/76 -'1(4$,*6 , /( '-(-97,+ -1,'.,()#&;# '12#&(%+ ,

-1,:,1(/0 -#1,*&;#&5 '12#&(%+



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

169


?71,6 V (14 %1'6): A(D$-B-()C )$( P<E"(D2()&. Q&'0.*

• J(&#2320 &., -'1('<4)'+, /#( .,*6 &/,-,E6 .,* -1,21A))#.,6 (O. ?-,*/,*CA9# , 2 %1'6)

• >(,.'<+,9,2(/0 N1'*+# & R+A-.*F5 (O. ?-,*/,*CA9# , 2 %1'6)

• J-(9,276 &.#$(,$1,);#6 .3+ C(,'-(&.5)4+3+ '/.46 .56 '/-#;$'*&56 (T1,&/'/95)7+,6

U)(95.06 #-4 ., @1#:';, K(#&E+$'&56 O-,*$%+ /#( O.#$(,$1,);#6 .,* KTM , 2 %1'6)

• J-(<'(15)#.(/4.5.# /#( 5 &E+$'&0 .56 )' .(6 C(,'-(&.0)'6 – K(#<';1(&5 -'1(CA99,+.,6

/#( '-(<'(15)#.(/0 58(/0 (T1,&/'/95)7+,6 U)(95.06 #-4 ., H)0)# ?5<#+(/%+

T'1(CA99,+.,6 .,* KTM , 2 %1'6)

• JUG /#( :#1)#/'*.(/0 C(,)5<#+;# (T1,&/'/95)7+,6 U)(95.06 #-4 .,+ J8+(/4 U12#+(&)4

G#1)A/3+ , 2 %1'6)

• L#(+,.,);# /#( ':'*17&'(6 (T1,&/'/95)7+,6 U)(95.06 #-4 .,+ U12#+(&)4 >(,)5<#+(/06

V$(,/.5&;#6 , 2 %1'6)

• T14.*-# /#( +,)(/4 -9#;&(, 2(# .# (#.1,.'<+,9,2(/A -1,Q4+.# (T1,&/'/95)7+,6 U)(95.06

#-4 ., J8+(/4 L7+.1, RF(,9425&56 .56 T,(4.5.#6 /#( H'<+,9,2;#6 &.5+ !2';# , 2 %1'6)

?71,6 VV (14 %1'6): +(&0;(D2#"&10* D28 +(&"8M$1.$

• J-(&.5),+(/0 !-,&.01(F5 /#( ?A1/'.(+2/ (T1,&/'/95)7+,6 U)(95.06 #-4 .5 >(,)5<#+;# , 2

%1'6)

• >(,.'<+,9,2(/0 J-(<'(15)#.(/4.5.# & L#(+,.,);# (O. ?-,*/,*CA9# , 2 %1'6)

• K(,;/5&5 (?A+#.D)'+.) /#( K(#<';1(&5 U9(/06 T,(4.5.#6 (T1,&/'/95)7+,6 U)(95.06 #-4

.5 >(,.'<+,9,2(/0 >(,)5<#+;# , 2 %1'6)

• K(#<';1(&5 T#1#23206 &' T'1(CA99,+ J9'2<4)'+56 T,(4.5.#6 (T1,&/'/95)7+,6 U)(95.06

#-4 .5 >(,.'<+,9,2(/0 >(,)5<#+;# , 2 %1'6)

• N1'*+# /#( R+A-.*F5 &.5 G#1)#/'*.(/0 >(,)5<#+;# (T1,&/'/95)7+,6 U)(95.06 #-4 .5

G#1)#/'*.(/0 >(,)5<#+;# , 2 %1'6)

• L9(+(/0 R+A-.*F5 G#1)A/3+ (T1,&/'/95)7+,6 U)(95.06 #-4 .5 G#1)#/'*.(/0 >(,)5<#+;# ,

2%1'6

)

• H, V#.1(/4 H)0)# )(#6 G#1)#/'*.(/06 J.#(1';#6 /#( .# R+.(/';)'+# .,* (T1,&/'/95)7+,6

U)(95.06 #-4 .5 G#1)#/'*.(/0 >(,)5<#+;# , 2 %1'6)



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

170

1L9H:9FB7J> - EFGABCAO@A

1?H8<@A 'R:LC:LX6OA , J-;/,*1,6 L#8520.1(# ?,1(#/06 @'+'.(/06.

!<:BC=CO87I9:F &7FO8HI>


+@HO:>: LRV"UHU?VR & JTV=JVPI?RHVLUHIHR 1LNN<AS=@>: LRPR@VR""IO IZVRO , ?TRLU!PUO VYR""IO "CGJH8>: "&,:;#" RJ ISBN: 978-960-6706-33-2,?GFCJ> "QG:5:>: 1104

+@HO:>: I &.1#.52(/0 $(#<';1(&5 .56 .'<+,9,2;#6 /#( .56 /#(+,.,);#6

1LNN<AS=@>: White Margaret A.,Bruton Garry D."CGJH8>: JLKUOJVO LPVHVLI RJ TCG:B8 : 15 7/$./2010ISBN: 978-960-218-674-9,?GFCJ> "QG:5:>: 11600

+@HO:>: J-(<'(15)#.(/4.5.# /#( /#(+,.,);#

1LNN<AS=@>: =#.D5/3+&.#+.;+,* @ , @3+(A$56 I. V.TCG:B8 : 15 7/$./2009"CGJH8>: @. KRPKR"UO - L . KRPKR"UO U.J.ISBN: 978-960-01-1253-5,?GFCJ> "QG:5:>: 31411

+@HO:>: R1<76 ?A1/'.(+2/ 1LNN<AS=@>: Lamb Charles, Hair Joseph, McDaniel CarlTCG:B8 : 15 7/$./2004EFAMIH8> ("CGJH8>): @.TRPVLUO & OVR JJ ISBN: 978-960-286-753-2,?GFCJ> "QG:5:>: 16297

+@HO:>: VKVUG!_R HU! ?RPLJHV"@L 1LNN<AS=@>: PETER FISKTCG:B8 : 15 /2010EFAMIH8> ("CGJH8>): JLKUOJVO LZJVKRPVM?UO JTJ ISBN: 978-960-461-384-7,?GFCJ> "QG:5:>: 48769

+@HO:>: J-(<'(15)#.(/4.5.# , /#(+,.,);# /#( business clusters

1LNN<AS=@>: T(-'14-,*9,6 TA+,6 @.TCG:B8 : 15 7/$./ 2008EFAMIH8> ("CGJH8>): JLKUOJVO OHR?U!ZI RJ ISBN: 978-960-351-771-9,?GFCJ> "QG:5:>: 23102



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

172

"$E$,- ."'-+- -(&1&3$&4&2$-1


OH’ J 2 0 2 2


U( &.4<,( .,* )#80)#.,6 ';+#(:

#) +# #-,/.0&,*+ ,( :,(.5.76 2+%&'(6 2(# .(6 $*&9'(.,*12;'6 .,* #+,&,-,(5.(/,E

&*&.0)#.,6.

C) +# /#.#+,0&,*+ .5+ &*)C,90 .,* #+,&,-,(5.(/,E &*&.0)#.,6 &.5+ *2';# /#( .(6

#&87+'('6.

2) +# )'9'.0&,*+ .,*6 .14-,*6 )' .,*6 ,-,;,*6 5 '+;&<*&5 0 /#.#&.,90 '($(/%+

#+,&,9,2(/%+ #-,/1;&'3+ )-,1'; +# ,$520&'( &.5+ -1495B5 0 //#( 8'1#-';# #&8'+'(%+.


M'315.(/4 )71,6

• K*&9'(.,*12;'6 .,* #+,&,-,(5.(/,E &*&.0)#.,6.

• R+,&,-1495B5 /#( #+,&,8'1#-';# - T1,&'22;&'(6.

• J)C49(#. J+'125.(/0 /#( -#85.(/0 #+,&,-,;5&5 . O<'$(#&)46 ')C,9;3+ 2(#

'+'125.(/0 #+,&,-,;5&5 . J)C49(# )' ,94/951,*6 )(/1,,12#+(&),E6 , )'

#-,),+3)7+# )#/1,)41(# , )' 2'+'.(/A .1,-,-,(5)7+,*6 :,1';6 , -,9*&8'+%+

*-,),+A$3+. J)C49(# 2'+'.(/,E *9(/,E (DNA).

• R+,&,#+'-A1/'('6. T13.,2'+';6 #+,&,#+'-A1/'('6. J-;/.5.'6 0 $'*.'1,2'+';6

#+,&,#+'-A1/'('6 - OE+$1,), C#1(A6 '-;/.5.56 #+,&,#+'-A1/'(#6 (AIDS) /#( , (46

.56 #+81%-(+56 #+,&,#+'-A1/'(#6 (HIV).

• R*.,#+,&;#. U12#+,'($(/A /#( O*&.5)#.(/A #*.,A+,&# +,&0)#.#. ?,+.79# D%3+

2(# #*.,A+,&# +,&0)#.# . R+,&,9,2(/76 #-,/1;&'(6 &.5+ #*.,#+,&;#. ?5<#+(&),;

2(# .5+ '-#2320 #*.,#+,&;#6. M'1#-';# #*.,A+,&3+ +,&5)A.3+.

• R+.($1A&'(6 *-'1'*#(&85&;#6. H#F(+4)5&5 /#.A Gell & Coombs. !-'1'*#(&85&;# )'&,9#C,E)'+5 #-4 IgE (.E-,* V) – L*..#1,.,F(/0 *-'1'*#(&85&;# 'F#1.%)'+5

#-4 #+.;&3)# (.E-,* VV) – !-'1'*#(&85&;# )'&,9#C,E)'+5 #-4 #+,&,&E)-9'2)#

(.E-,* VVV) – !-'1'*#(&85&;# '-(C1#$*+4)'+,* .E-,* (.E-,* IV, DTH).

• R+,&,9,2;# .3+ )'.#),&<'E&'3+. R+,&,9,2(/0 CA&5 .56 #-411(B56 ),&<'E)#.,6.

L9(+(/76 '/$59%&'(6 .56 #-411(B56 ),&<'E)#.,6. L9(+(/0 )'.#)4&<'*&5 .

R+,&,/#.#&.#9.(/0 8'1#-';#. R+,&,#+,<0 &.# #99,),&<'E)#.#.

• L#1/;+,6 /#( #+,&,-,(5.(/4 &E&.5)#. L#1/;+,6: -1,79'*&5 /#( ,+,)#.,9,2;#.

U2/,2,+;$(# /#( '-#2320 /#1/;+,*. K(#:*20 .3+ /#1/(+(/%+ /*..A13+ #-4 .5+ '-(.015&5 .,* #+,&,-,(5.(/,E &*&.0)#.,6. R+,&,8'1#-';# /#1/;+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

173

EFG6BC:9H=>

-FCAH=<@98 %O@KOFA , J-;/,*1,6 L#8520.1(# ?,1(#/06 R+,&,C(,9,2;#6.


H;.9,6: R"UOUZU@VR , 25 7/$,&5 O*221#:7#6: Goldsby R, Kindt T, Osborne B, Kuby JJ/$,.(/46 U;/,6: V#.1(/76 J/$4&'(6 T. =. T#&<#9;$5 H4-,6 & =14+,6 N/$,&56: 2012ISBN: 978-9963-716-14-2L3$(/46 J!KU]UO: 23076003

+@HO:>: ,4$($,/ -(&1&4&2$- 1LNN<ASIA>: 1LOO:NFCJ I<N: – =RF7IO=FA: !. 'R:Q<A "CG:HFCJ> &@C:>: University Studio Press+JR:> & %<J9:> TCG:B8>: 2011 ISBN: 960-12-2052-9 ,?GFCJ> ")E&U&1: 12832065

+@HO:>: 3-1$,/ -(&1&4&2$-, 4=FH:L<N@=> CAF GLBO=FH:L<N@=> H:L A9:B:R:F8HFC:Q BLBHD7AH:>

1LNN<ASIA>: Abbas AK, Lichtman AH"CG:HFCJ> &@C:>: V#.1(/76 J/$4&'(6 T. =. T#&<#9;$5 +JR:> & %<J9:> TCG:B8>: 2004 ISBN: 960-399-217-8 ,?GFCJ> ")E&U&1: 13256380

+@HO:>: $-+#$,/ -(&1&4&2$- 1LNN<ASIA>: -9ABH6BF:> 2=<7=9D>

"CG:HFCJ> &@C:>: J/$4&'(6 T#-#D0&5 +JR:> & %<J9:> TCG:B8>: 2000 ISBN: 960-02-1397-6,?GFCJ> ")E&U&1: 30142


+@HO:>: O5)'(%&'(6 $(#97F'3+ ?,1(#/06 R+,&,C(,9,2;#6 VV

1LNN<ASIA>: J-(/. L#8. R(/#.'1;+5 =9;<9(# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,E-,95 , 2013



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

174

EFGACHFCI> – 'AM8BFACI> 'IM:G:F K(#97F'(6 &., #):(87#.1, , C;+.', , /1(.(/0 &*D0.5&5 )' $(A9,2, /#( &*))'.,<0 .3+ :,(.5.%+ , $(#97F'(6 &'

'($(/A 87)#.# #-4 -1,&/'/95)7+,*6 ,)(95.76 , 59'/.1,+(/0 -9#.:41)# .,* )#80)#.,6 (e-class), '12#&;'6 -,*

&.51;D,+.#( &.5 )'97.5 /#( #+A9*&5 '-(&.5),+(/%+ A1813+ #-4 .5 &E2<1,+5 C(C9(,21#:;# .

2OPBBA EFGABCAO@A>

J995+(/0


U( :,(.5.76 #F(,9,2,E+.#( )' CA&5 .5+ '-;$,&0 .,*6 &' #)'12#&;# -,* C#&;D'.#( &.5 &E2<1,+5 C(C9(,21#:;#

/#( C)21#-.76 'F'.A&'(6 &., .79,6 .,* 'F#)0+,*.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

175

!"#$"%&'"(&

"!$4"2&'"(*(

'-./'-+*(

&76GA 3



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

176

E$E-,+$,/ !#-,+$,/ -1,/1/ $$ (1%&4$,/ "0-#'&2/)


]’ " 1 1 2 2


I K($#/.(/0 T1#/.(/0 a&/5&5 II 8# 2;+'( &' &*+'12#&;# )' '/-#($'*.(/76 ),+A$'6 .56

-'1(,<06 0 A99# '/-#($'*.(/A -9#;&(# , )' &/,-4 .5+ 'F,(/';3&5 .3+ :,(.5.%+/.1(%+ )'

.5+ -1,'.,()#&;# , ., &<'$(#&)4 /#( .5+ *9,-,;5&5 .56 $($#&/#9;#6 , %&.' +# #-,:'E2,+.#( -(8#+A 9A85 -,* &<'.;D,+.#( )' .(6 )'84$,*6 , .(6 ),1:76 , .# )7&# $($#&/#9;#6 /#(

$(#-#($#2%25&56.


U( :,(.5.76/.1('6 8# '+5)'138,E+ 2(# .,+ .14-, -1,21#))#.(&),E '+46 )#80)#.,6 , /#8%6

/#( 2(# -1#/.(/A D5.0)#.# -1,'.,()#&;#6 /#( &<'$(#&),E )(#6 $($#&/#9;#6 , -,* -17-'( +#

9#)CA+'( *-4B5 .,* , '/-#($'*.(/46 )7&3 -#1#/,9,E85&56 /#( $($#&/#9;#6 C(,9,2(/%+

)#85)A.3+ &' &<,9';# .56 -'1(,<06 0 /#( &' A99# '/-#($'*.(/A -9#;&(#. I K($#/.(/0 T1#/.(/0 a&/5&5 VV &*+,$'E'.#( #-4 &E&.5)# '-,-.';#6 .56.

EFG6BC:LBA

,AH=<@9A ,=G<6CA , Z7/.,1#6


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,* )#80)#.,6: KVKRLHVLI TPRLHVLI ROLIOI

1LNN<ASIA>: L#.'1;+# L'$1A/# +JR:> & %<J9:> TCG:B8>: R9'F#+$1,*-,95 , 2013 (R+7/$,.'6

O5)'(%&'(6)


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# , #:'+46 -#1#/,9,*8%+.#6 .5

$($#&/#9;# C(,9,2(/%+ )#85)A.3+ (0 A993+ )#85)A.3+ .,* /9A$,* TJ04) /#( #:'.71,*



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

178

",!-$E")1/ "(/4$,*(


]’ " 1 1 2 2


U &/,-46 .,* )#80)#.,6 ';+#( +# '(&A2'( .,*6/.(6 :,(.5.76/.1('6 &.# D5.0)#.# -,*

#:,1,E+ &' 49, ., :A&)# .,* &<'$(#&),E , .56 *9,-,;5&56 /#( .56 #F(,9425&56 )(#6 $1A&56/

'+46 -1,21A))#.,6 '/-#;$'*&56 2(# '+59;/,*6.


H, )A85)# -'1(9#)CA+'(: .5+ ,1(,87.5&5 .,* -'$;,* .56 J/-#;$'*&56 J+59;/3+ /#( )(#

&E+.,)5 #+#$1,)0 .,* 8'&),E &.5+ J99A$# –:,1';6 /#( $,)76 *9,-,;5&56 , .5+ '(&#2320 &.(6

C#&(/76 7++,('6 , #1<76 /#( )'84$,*6 .56 J/-#;$'*&56 J+59;/3+ , &.(6 /E1('6 8'31;'6

)A85&56 '+59;/3+ )' 7):#&5 &.5 8'31;# .56 ?'.#&<5)#.;D,*&#6 ?A85&56 , &.5+ R+,(/.0

/#( EF A-,&.A&'36 E/-#;$'*&5 , &.5 <10&5 '+'125.(/%+ '/-#($'*.(/%+ .'<+(/%+ , /#8%6 /#(

)'84$3+ #F(,9425&56. O., )A85)# -'1(9#)CA+'.#( , '-;&56 , 5 '+4.5.# U '/-#($'*.06

'+59;/3+ 36 '1'*+5.06 , 5 ,-,;# -1#2)#.'E'.#( .(6 C#&(/76 #1<76 .56 -,(,.(/06 71'*+#6 ,)7&3 .56 '/-4+5&56 )(/1%+ '1'*+%+ , .(6 ,-,;'6 8# *9,-,(0&,*+ , )4+,(/'6 .,*6 0 &' )(/176

,)A$'6 , <15&(),-,(%+.#6 .(6 .'<+(/76 .56 &*+7+.'*F56 0 //#( .56 -#1#.015&56 , /#( 8#

-#1,*&(A&,*+ &.5+ ,9,)79'(#.

EFG6BC:LBA

,AH=<@9A ,=G<6CA , Z7/.,1#6


H;.9,6: J/-#($'*.76 J+59;/3+ &.5+ J99A$# O*221#:7#6: R(/#.'1;+5 L'$1A/# J/$,.(/46 U;/,6: R:,( L*1(#/;$5 H4-,6 & =14+,6 N/$,&56: M'&&#9,+;/5 , 2009ISBN: 978-960-467-075-8L3$(/46 J!KU]UO: 5822



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

179


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,* )#80)#.,6: JLTRVKJ!OI J"IZVLY"


O5)'(%&'(6)


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 2+%&'(6 , $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .'<+(/76 4-36 5 '12#&;# &'

,)A$'6 , ., -#;F(), 1493+ , 5 -1,&,),;3&5 , 5 &*D0.5&5 , /.9. I '(&025&5 <15&(),-,(';.#(

'-(/,*1(/A &.(6 '+'125.(/76 '/-#($'*.(/76 .'<+(/76 /#( &*)-951%+'( .(6 2+%&'(6 -,*

<1'(AD'.#( +# #-,/.58,E+.

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 2;+'.#( )' 21#-.76 'F'.A&'(6 /#.A .(6 'F'.#&.(/76 -'1(4$,*6. L#8%6 .,

)A85)# &.51;D'.#( &' '+'125.(/76 /#( &*))'.,<(/76 )'84$,*6 )A85&56 , 5 -#1,*&;# /#(

&*))'.,<0 .3+ :,(.5.%+/.1(3+ &.(6 -#1#$4&'(6 8'31';.#( /'+.1(/06 &5)#&;#6 /#( 2(# .,+

942, #*.4 &*+*-,9,2;D'.#( &.5+ .'9(/0 #F(,9425&5 . J+#99#/.(/A , #+#.;8'+.#( )(/176

'12#&;'6 &' :,(.5.76/.1('6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

182

E$E-,+$,/ !#-,+$,/ -1,/1/ $ ('$,#&E$E-1,-4$-)


1+’ " 1 1 2 2


O/,-46 .56 K($#/.(/06 T1#/.(/06 a&/5&56 V ';+#( +# #&/58,E+ ,( :,(.5.76/.1('6 )7&3

)(/1,$($#&/#9;#6 (microteaching) &' $($#/.(/76 $'F(4.5.'6 /#( +# )-,17&,*+ &.5 &*+7<'(# +#

.(6 #F(,-,(0&,*+ )' #-,.'9'&)#.(/4 .14-, &.5+ .AF5 .


M# -#1,*&(#&.,E+ ,( 8'315.(/76 -1,b-,87&'(6 , .# C#&(/A &.,(<';# .56 )(/1,$($#&/#9;#6 /#(

.5 &*)C,90 .56 &.5+ '/-#;$'*&5 /#( &.5+ '-()41:3&5 .3+ '/-#($'*.(/%+. M#

-1#2)#.,-,(58'; #.,)(/0 A&/5&5 .3+ :,(.5.%+/.1(%+: -1,'.,()#&;# , $('F#2320 ,

-#1#.015&5 , &*D0.5&5 /#( #F(,9425&5 )(#6 )(/1,$($#&/#9;#6.

EFG6BC:LBA

,AH=<@9A ,=G<6CA , Z7/.,1#6


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,* )#80)#.,6 TPRLHVLI ROLIOI V


O5)'(%&'(6)


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 $($#/.(/76 $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .5+ -#1,*&;#&5 )(/1%+

$($#/.(/%+ '+,.0.3+ (?(/1,$($#&/#9;'6).

2OPBBA EFGABCAO@A>

J995+(/A




!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

183

I #F(,9425&5 2;+'.#( )' CA&5 .5+ '+'124 &*))'.,<0 , .(6 -#1,*&(A&'(6 .3+ )(/1,$($#&/#9(%+

0 //#( )(/176 21#-.76 '12#&;'6 .3+ :,(.5.%+/.1(%+.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

184

E$E-,+$,/ '".&E&4&2$-


1+’ " 1 1 2 2


H, )A85)# #-,&/,-'; &.5+ 'F,(/';3&5 .3+ :,(.5.%+/.1(%+ )' .(6 C#&(/76 7++,('6 .56

$($#/.(/06 /#( .# $,)(/A &.,(<';# .56 $($#&/#9;#6 CA&'( /#( .3+ +73+ 8'315.(/%+ .A&'3+.


JF'.AD,+.#( 87)#.# -1,21#))#.(&),E /#( &<'$(#&),E .56 $($#&/#9;#6 , )'84$3+ /#(

.'<+(/%+ $($#&/#9;#6 , R+#9*.(/%+ T1,21#))A.3+ /#( &<,9(/%+ '2<'(1($;3+ , .14-3+

,12A+3&56 .56 )#85&(#/06 $(#$(/#&;#6 &.5 &<,9(/0 .AF5 , $(#<';1(&56 .,* $($#/.(/,E <14+,*

/#( '+#99#/.(/%+ ),1:%+ #F(,9425&56. J($(/A -#1,*&(AD,+.#( 5 )78,$,6 project /#( 5 ,)#$,-

&*+'12#.(/0 $($#&/#9;# (-1,b-,87&'(6 , <#1#/.51(&.(/A /#( &.A$(# *9,-,;5&06 .,*6).

EFG6BC:LBA

,AH=<@9A ,=G<6CA , Z7/.,1#6


-H;.9,6: T1#/.(/46 U$5246 .,* J/-#($'*.0 - O*221#:7#6: D. Noye & J. Piveteau- J/$,.(/46 U;/,6: ?'.#;<)(, -N.,6 N/$,&56: 1999- ISBN: 960-375-013-1- L3$(/46 J!KU]UO= 24248

H;.9,6: J(&#2320 &.5 M')#.(/0 .56 K($#/.(/06 -O*221#:7#6: K5)0.156 =#.D5$0),* -J/$,.(/46 U;/,6: R:,( L*1(#/;$5 -N.,6 N/$,&56: 2007- ISBN: 978-960-343-960-8- L3$(/46 J!KU]UO= 6944



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

185


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ ' /-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 2+%&'(6 , $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .'<+(/76 4-36 5 '12#&;# &'

,)A$'6 , ., -#;F(), 1493+ , 5 -1,&,),;3&5 , 5 &*D0.5&5 , /.9. I '(&025&5 <15&(),-,(';.#( '-(/,*1(/A &.(6 '+'125.(/76 '/-#($'*.(/76 .'<+(/76 /#( &*)-951%+'( .(6 2+%&'(6 -,*

<1'(AD'.#( +# #-,/.58,E+. O., )A85)# -1,&/#9,E+.#( 2(# +# ),(1#&.,E+ .5+ ')-'(1;#

.,*6 /#( '/-#($'*.(/,; .56 &<,9(/06 -1AF56.

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 2; +'.#( )' 21#-.76 'F'.A&'(6 /#.A .(6 'F'.#&.(/76 -'1(4$,*6. L#8%6 .,

)A85)# &.51;D'.#( &' '+'125.(/76 /#( &*))'.,<(/76 )'84$,*6 )A85&56 , 5 -#1,*&;# /#(

&*))'.,<0 .3+ :,(.5.%+/.1(3+ &.(6 -#1#$4&'(6 8'31';.#( /'+.1(/06 &5)#&;#6 /#( 2(# .,+

942, #*.4 &*+*-,9,2;D'.#( &.5+ .'9(/0 #F(,9425&5 . J+#99#/.(/A , #+#.;8'+.#( )(/176

'12#&;'6 &' :,(.5.76/.1('6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

186

1)'3&)4")+$,/ ,-$ ",!-$E")+$,/ \)%&4&2$-


1+’ " 1 1 2 2


H, )A85)# '-(/'+.1%+'.#( &.5 )'97.5 .3+ C#&(/%+ 8'31(%+ )A85&56 /#( .3+

&*+#(&85)#.(/%+ -#1#)7.13+ -,* ')-97/,+.#( &.5 $(#$(/#&;# .56 )A85&56 (#.,)(/76

$(#:,176 , 7++,(# .,* '#*.,E , #*.,'/.;)5&5 , -'-,(80&'(6 '-A1/'(#6 /.A.) /#( '-51'AD,*+ .,

B*<,/,(+3+(/4 /9;)# .56 .AF56. V$(#;.'15 7):#&5 $;+'.#( &., 149, .,* '/-#($'*.(/,E ,

/*1;36 &' D5.0)#.# 72/#(1,* '+.,-(&),E /#( -#17)C#&56 &., -9#;&(, /#( .# 41(# .,* '-#22'9)#.(/,E .,* 149,*.


JF'.AD,+.#( ,( &*+587&.'1'6 $*&/,9;'6 &*)-'1(:,1A6 /#( &*+#(&80)#.,6 )' .(6 ,-,;'6

71<'.#( #+.()7.3-,6 , '/-#($'*.(/46 &.5+ -1AF5 /#( #:,1,E+ .5 &<,9(/0 '-(8'.(/4.5.# ,

.5+ $(#.#1#<0 '99'())#.(/06 -1,&,<06/*-'1/(+5.(/4.5.#6 (KJT-!), .5+ +.1,-#94.5.# /#(

/,(+3+(/0 &*&.,90 , .(6 )#85&(#/76 $*&/,9;'6 , ., A2<,6 , .(6 $(A<*.'6 #+#-.*F(#/76

$(#.#1#<76 /.A.

O' 4 ,.( #:,1A .5+ B*<,9,2;# .,* '/-#($'*.(/,E , ., )A85)# #&<,9';.#( )' .5 )'97.5

'+$,#.,)(/%+ )'.#C95.%+ , 4-36 -1,&3-(/4.5.# , #F;'6 , -'-,(80&'(6 , '12#&(#/4 &.1'6 ,

'-#22'9)#.(/0 7++,(# .,* '#*.,E /#( #*.,'/.;)5&5 .

T#1,*&(AD'.#( '+$'(/.(/0 ':#1),20 )'84$3+ , &.1#.52(/%+ /#( .'<+(/%+ <'(1(&),E .3+

$*&/,9(%+ &*)-'1(:,1A6 /#( &*+#(&80)#.,6 #-4 .,+ '/-#($'*.(/4 , /#8%6 /#( $'F(,.0.3+

&*)C,*9'*.(/06 /#( &*+'12#&;#6 )' .5+ ,(/,27+'(#.

EFG6BC:LBA

,AH=<@9A ,=G<6CA , Z7/.,1#6


- H;.9,6: T#($#232(/0 d*<,9,2;# - O*221#:';6: J*.K5)5.14-,*9,6 /#( U*. L#94*15 -

R+.3+,-,E9,* - J/$,.(/46 U;/,6: VY"-JZZI" -N.,6 N/$,&56: 2010

- ISBN: 978-960-286-998-7- L3$(/46 J!KU]UO= 71957



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

187


+@HO:>: OI?JVYOJVO 2(# .(6 #+A2/'6 .,* )#80)#.,6 O*)C,*9'*.(/0 & J/-#($'*.(/0 d*<,9,2;#

1LNN<ASIA>: L#.'1;+# L'$1A/#

+JR:> & %<J9:> TCG:B8>: R9'F#+$1,*-,95 , 2013 (R+7/$,.'6 O5)'(%&'(6)


I $($#/.(/0 -1,&722(&5 -,* <15&(),-,(';.#( ';+#( 5 C(3)#.(/0 )A85&5 . U( :,(.5.76/.1('6

&*))'.7<,*+ '+'12A &.5+ '/-#($'*.(/0 $(#$(/#&;# /#.A .5 $(A1/'(# .,* )#80)#.,6 ,

-1,&'22;D,+.#6 2+%&'(6 , $'F(4.5.'6 /#( &.A&'(6 )7&# #-4 .'<+(/76 4-36 5 '12#&;# &' ,)A$'6 , ., -#;F(), 1493+ , 5 -1,&,),;3&5 , 5 &*D0.5&5 , /.9. I '(&025&5 <15&(),-,(';.#(

'-(/,*1(/A &.(6 '+'125.(/76 '/-#($'*.(/76 .'<+(/76 /#( &*)-951%+'( .(6 2+%&'(6 -,*

<1'(AD'.#( +# #-,/.58,E+.

2OPBBA EFGABCAO@A>

J995+(/A


I #F(,9425&5 2;+'.#( )' 21#-.76 'F'.A&'(6 /#.A .(6 'F'.#&.(/76 -'1(4$,*6. L#8%6 .,

)A85)# &.51;D'.#( &' '+'125.(/76 /#( &*))'.,<(/76 )'84$,*6 )A85&56 , 5 -#1,*&;# /#(

&*))'.,<0 .3+ :,(.5.%+/.1(3+ &.(6 -#1#$4&'(6 8'31';.#( /'+.1(/06 &5)#&;#6 /#( 2(# .,+

942, #*.4 &*+*-,9,2;D'.#( &.5+ .'9(/0 #F(,9425&5 . J+#99#/.(/A , #+#.;8'+.#( )(/176

'12#&;'6 &' :,(.5.76/.1('6.



ME!"# $$$

,"$2+2$(- 3&.-2-



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

189

0&$+/+$,/ '"#$'(-

1. EFGACHFC6 1LNN<677AHA

N+# &E221#))# 2(# /A8' )A85)# <,152';.#( $31'A+ &.,*6 :,(.5.76 )'.A #-4 '-(9,20 .,*6 &.5+ #1<0 /A8' 'F#)0+,* &., ,-,;, $($A&/'.#( ., )A85)#. I '-(9,20 -1#2)#.,-,(';.#( #-4 /#.A9,2, -1,.'(+4)'+3+ &*221#))A.3+ , .,+ ,-,;, '(&52';.#( , $($A&/3+ .,* )#80)#.,6

/#( .,+ ,-,;, '-(/*1%+'( 5 @'+(/0 O*+79'*&5 .,* H)0)#.,6. R-4 ., R/#$5)#Q/4 7.,6 2010-

2011 5 $(#+,)0 &*221#))A.3+ 2;+'.#( )7&3 .,* &*&.0)#.,6 «JE$,F,6».

2. /O=CH<:9FC6 'AMD7AHA

H, KTM -#17<'( *-51'&;'6 I9'/.1,+(/%+ ?#85)A.3+ &.# -9#;&(# .56 T9#.:41)#6

R&E2<1,+56 H59'/-#;$'*&56 e-Class:

http://eclass.duth.gr/eclass

O., e-class #+#1.%+.#( -951,:,1;'6 , #+#/,(+%&'(6 /#( 4.( A99, /1;+,*+ ,( $($A&/,+.'6 ,/#8%6 /#( ,( #+#/,(+%&'(6 -,* #:,1,E+ &.(6 '12#&.51(#/76 #&/0&'(6.

3. 1@HFB8

O.(6 /.(1(#/76 '2/#.#&.A&'(6 .3+ T#($#232(/%+ H)5)A.3+ 9'(.,*12'; G,(.5.(/0 Z7&<5 2(# .5 &;.(&5 .3+ :,(.5.%+ .3+ T#($#232(/%+ H)5)A.3+ /#( .3+ H)5)A.3+ V#.1(/06 /#( ?,1(#/06 >(,9,2;#6 & @'+'.(/06. K(/#;3)# $31'A+ &;.(&56 7<,*+ ,( :,(.5.76 -,* -951,E+ .(6

-1,b-,87&'(6 -,* -1,C97-,+.#( #-4 ., +4), (#+#9*.(/76 -951,:,1;'6 -#17<,+.#( #-4 .5

@1#))#.';#). ?'.A .,+ 79'2<, .3+ $(/#(,9,25.(/%+ <,152';.#( /A1.# &;.(&56 &.,*6 :,(.5.76 -,* $(/#(,E+.#( $31'A+ &;.(&5 . U( :,(.5.76 -,* $'+ -951,E+ .(6 -1,b-,87&'(6 2(# $31'A+

&;.(&5 7<,*+ $(/#;3)# &;.(&56 #99A /#.#CA9,*+ ., #+.;.(), .,* &(.51'&;,*.

4. 1HINAB8

G,(.5.(/0 J&.;# $'+ *-A1<'( -1,6 ., -#14+ 2(# .5 &.72#&5 .3+ :,(.5.%+ .,* K.T.M

&.5+ R9'F#+$1,E-,95 . Y&.4&, 2(# /A8' #/#$5)#Q/4 7.,6 'F#&:#9;D,+.#( )(&83)7+# $3)A.(#

&.5+ -495 .56 R9'F#+$1,E-,956 2(# .5 &.72#&5 .3+ :,(.5.%+. H# /1(.01(# '-(9,206 .3+

:,(.5.%+ -,* 8# &.'2#&.,E+ &' F'+,$,<';# , 4-36 '-;&56 /#( .# $(/#(%)#.# /#( ,( *-,<1'%&'(6 .3+ &.'2#D4)'+3+ :,(.5.%+ ':#1)4D,+.#( &E):3+# )' .# 4&# -1,C97-'( ,



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

190

«@'+(/46 L#+,+(&)46 Z'(.,*12;#6 G,(.5.(/%+ J&.(%+ .,* K.T.M.». T'1(&&4.'1'6 -951,:,1;'6

-#17<,+.#( #-4 .5 @1#))#.';# .,* H)0)#.,6.

5. EFCAF:O:N8HFC6 1@HFB8> CAF 1HINAB8>

1) R;.5&5 5 ,-,;# <,152';.#( #-4 .5+ @1#))#.';#

2) J//#8#1(&.(/4 &5)';3)# .56 J:,1;#6 2(# .5+ ,(/,+,)(/0 -'1;,$, .,* .17<,+.,6 7.,*6 (.3+

2,+73+ 0 .,* :,(.5.0 'A+ *-,CA99'( , ;$(,6 :,1,9,2(/0 $093&5 )3) T(&.,-,(5.(/4 U(/,2'+'(#/06 /#.A&.#&56 #-4 .,+ K0), 0 .5+ L,(+4.5.#

4) !-'E8*+5 K093&5 .,* ". 1599/86 4-,* 8# $59%+'.#( 5 )4+()5 /#.,(/;# .3+ 2,+73+

5) U( *-,B0:(,( -,* '-(/#9,E+.#( 942,*6 *2';#6 ,:';9,*+ +# -1,&/,);&,*+ C'C#;3&5 #1)4$(#6 -13.,CA8)(#6 *2'(,+,)(/06 '-(.1,-06 4-,* 8# .'/)51(%+,+.#( ,( 942,( #*.,; 6) U( *-,B0:(,( -,* 7<,*+ #$'9:4 :,(.5.0 0 #$'9:4 -,* *-51'.'; .5+ &.1#.(3.(/0 .,*

85.';# ,:';9,*+ +# -1,&/,);&,*+ .5+ #+A9,25 C'C#;3&5 #-4 .5+ #1)4$(# *-51'&;#

7) U( :,(.5.76 -,* ';+#( .7/+# -,9E.'/+56 ,(/,27+'(#6 ,:';9,*+ +# *-,CA9,*+ -(&.,-,(5.(/4

-,9*.'/+;#6

T'1(&&4.'1'6 -951,:,1;'6 -#17<,+.#( #-4 .5 @1#))#.';# .,* H)0)#.,6.

6. )N=F:9:7FCD !=<@MAOW8

U( :,(.5.76 $(/#(,E+.#( -901,*6 (#.1,:#1)#/'*.(/06 /#( +,&,/,)'(#/06 -'1;8#9B56.

@(# ., &/,-4 #*.4 , &' 4&,*6 ., '-(8*),E+ , <,152';.#( )' .5+ '221#:0 #-4 .5 @1#))#.';# .,*

H)0)#.,6 C(C9(A1(, *2';#6 , ., ,-,;, #+#+'%+'.#( /A8' <14+,.

!2'(,+,)(/0 -'1;8#9B5 $(/#(,E+.#( ,( -1,-.*<(#/,; /#( )'.#-.*<(#/,; :,(.5.76 .3+

R.J.V , 5)'$#-,; , ,),2'+';6 /#( #99,$#-,; 2(# $(A&.5)# ;&, -1,6 .# 7.5 :,;.5&56 -,*

-1,C97-,+.#( 36 '9A<(&.5 $(A1/'(# .3+ -1,-.*<(#/%+ &-,*$%+ .,* H)0)#.,6

-1,&#*F5)7+, /#.A ., 0)(&*. T1,/'()7+,* 2(# ., .'9'*.#;, 7.,6 &-,*$%+ 5 -'1;8#9B5 -#1#.';+'.#( /#( )'.A .5 90F5 .,* #/#$5)#Q/,E 7.,*6 )7<1( 31 K'/')C1;,* 2(# 4&,*6 $'+

7<,*+ 9AC'( .,+ .;.9, &-,*$%+ .,*6 )7<1( .4.'. R+#9*.(/4.'1'6 -951,:,1;'6 -'1(7<,+.#( &.,+ «L#+,+(&)4 !2'(,+,)(/06 T'1;8#9B56 G,(.5.%+».

7. EF=LC:OQ9B=F> CAH6 HF> '=HACF9DB=F>

U( :,(.5.76 $(/#(,E+.#( 7/-.3&5 '-; .,* '(&(.51;,* &.(6 )'.#/(+0&'(6 .,*6 &.,

'&3.'1(/4 .56 <%1#6 -,* $(#),1:%+,+.#( 36 'F06:

" O.(6 #&.(/76 &*2/,(+3+;'6 .56 -4956 4-,* '$1'E'( ., H)0)# -,* :,(.A ';+#( $31'A+.

" O.(6 ,$(/76 *-'1#&.(/76 &*2/,(+3+;'6 /#.A 25% /#( &.(6 &($51,$1,)(/76 &*2/,(+3+;'6

/#.A 25%.

" L#.A .(6 )'.#/(+0&'(6 .,*6 ,( :,(.5.76 ';+#( *-,<1'3)7+,( +# '-($'(/+E,*+ .,

$'9.;, .,* '($(/,E '(&(.51;,* .,*6 (-A&,) -,* <,152';.#( #-4 .5+ @1#))#.';#.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

191

8. 3<AX=@A-)R:H<:S@=>

@(# .,*6 -1,-.*<(#/,E6 :,(.5.76 (&<E'( ., &E&.5)# /1#.(/06 )71()+#6 -,* -'1(9#)CA+'( $E, /#.52,1;'6: *-,.1,:;'6 '-;$,&56 /#( *-,.1,:;'6 /#( $A+'(# '+;&<*&56. U( *-,.1,:;'6 '-;$,&56 <,152,E+.#( )' #-,/9'(&.(/4 /1(.01(, .5+ #/#$5)#Q/0 '-;$,&5 .,*

:,(.5.0 . U( *-,.1,:;'6 /#( .# $A+'(# '+;&<*&56 <,152,E+.#( )' -1%., /1(.01(, .5+ ,(/,+,)(/0 /#.A&.#&5 .,* :,(.5.0 /#( )' $'E.'1, /1(.01(, .5+ '-;$,&5 .,*. T'1(&&4.'1'6 -951,:,1;'6

-#17<,+.#( #-4 .5 @1#))#.';# .,* H)0)#.,6.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

192

9. "CRAFG=LHFC6 !<:N<677AHA

9.1 SOCRATES

H, -1421#))# SOCRATES #-,.'9'; ., -1421#µµ# $1A&56 .56 J*13-#Q/06 J-(.1,-06 2(#

.5 &*+'12#&;# &.,+ .,µ7# .56 J/-#;$'*&56. J;+#( 7+# -1421#µµ#-,µ-179# -,* /#9E-.'( /#( &*+'<;D'( .(6 $1#&.51(4.5.'6 -#9#(4.'13+ -1,21#µµA.3+ '/-#;$'*&56 /#( /#.A1.(&56 ,4-36 .# ERASMUS, LINGUA, EURIDICE, ARION, COMENIUS. U( <%1'6 -,* &*µµ'.7<,*+ &., T1421#µµ#

Socrates, ';+#( .# 27 /1A.5 -µ795 .56 J*13-#Q/06 N+3&56 , ., Z(<.'+&.A(+ , 5 ",1C52;# (&.#

-9#;&(# .56 O*µ:3+;#6 2(# .,+ J*13-#Q/4 U(/,+,µ(/4 <%1,), /#8%6 /#( 5 H,*1/;#.

H, .µ0 µ# .,* SOCRATES 2(# .5+ .1(.,CA8µ(# '/-#;$'*&5 ,+,µAD'.#( ERASMUS /#( #-,.'9'; &*+7<'(# , &' #+#8'315 µ7+5 /#( #+'-.*2µ7+5 µ,1:0 , .,* -1,21Aµµ#.,6 J*13-#Q/06

$1A&56 2(# .5+ /(+5.(/4.5.# &-,*$#&.%+ T#+'-(&.5 µ;3+. H, -1421#µµ# <,152'; *-,.1,:;'6

/(+5.(/4.5.#6 &' -,9976 <(9(A$'6 &-,*$#&.%+ .56 .1(.,CA8µ(#6 '/-#;$'*&56 , '+%

-#1A9959# '+$(#:71'.#( 2(# .5+ '+;&<*&5 .56 J*13-#Q/06 $(A&.#&56 .3+ &-,*$%+ 2(#

&-,*$#&.76 -,* $'+ &*µµ'.7<,*+ Aµ'&# &' #+.#99#276.

9.2 ERASMUS

H, .)0)# .,* SOCRATES 2(# .5+ .1(.,CA8)(# '/-#;$'*&5 ,+,)AD'.#( ERASMUS /#( #-,.'9'; &*+7<'(# , &' #+#8'315)7+5 /#( #+'-.*2)7+5 ),1:0 , .,* -1,21A))#.,6 J*13-#Q/06

$1A&56 2(# .5+ /(+5.(/4.5.# &-,*$#&.%+ T#+'-(&.5);3+. H, -1421#))# <,152'; *-,.1,:;'6

/(+5.(/4.5.#6 &' -,9976 <(9(A$'6 &-,*$#&.%+ .56 .1(.,CA8)(#6 '/-#;$'*&56 , '+%

-#1A9959# '+$(#:71'.#( 2(# .5+ '+;&<*&5 .56 J*13-#Q/06 $(A&.#&56 .3+ &-,*$%+ 2(#

&-,*$#&.76 -,* $'+ &*))'.7<,*+ A)'&# &' #+.#99#276.

I $5)(,*12;# $(#-#+'-(&.5)(#/%+ -1,21#))A.3+ &*+'12#&;#6 2(# .5+ /(+5.(/4.5.# .3+

:,(.5.%+ ($(A1/'(#6 #-4 .1'(6 )0+'6 736 7+# 7.,6) /#( 2(# $($A&/,+.'6 (#-4 );# 736 ,/.%

'C$,)A$'6), 5 ,12A+3&5 '+.#.(/%+ -1,21#))A.3+ &E+.,)56 $(A1/'(#6 2(# '/-#($'*.(/,E6 /#( &-,*$#&.76 , 5 #-4 /,(+,E #+A-.*F5 -1,21#))A.3+ &-,*$%+ , ';+#( )'1(/76 #-4 .(6

$1#&.51(4.5.'6 -,* -'1(9#)CA+,+.#( &., -9#;&(, .,* ERASMUS.

H( -1,&:71'( ., ERASMUS &.,*6 :,(.5.76:To -1421#))# ERASMUS $;+'( .5 $*+#.4.5.# &.,*6 :,(.5.76 , µ7&3 .3+ *-,.1,:(%+ , +#

-1#2µ#.,-,(0&,*+ µ71,6 .3+ &-,*$%+ .,*6 (#-4 .1'(6 µ0+'6 736 7+# 7.,6) &' -#+'-(&.0 µ(,

A99,* /1A.,*6-µ79,*6. H, µ71,6 #*.4 .3+ &-,*$%+ #+#2+31;D'.#( -90136 µ7&# #-4 ., ECTS,

$59#$0 µ7&# #-4 ., J*13-#Q/4 OE&.5 µ# ?'.#:,1A6 R/#$5 µ#Q/%+ ?,+A$3+ (European Credit

Transfer System, C9.-#1#-A+3).

H, ERASMUS ';+#( #+,(<.4 &' 49# .# ';$5 ($1*µA.3+ .1(.,CA8µ(#6 '/-#;$'*&56 /#( #-'*8E+'.#( &' 49,*6 .,*6 /9A$,*6 /#( C#8µ;$'6 &-,*$%+ , &* µ-'1(9#µC#+,µ7+56 /#( .56

$($#/.,1(/06 $(#.1(C06.



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

193

U( :,(.5.76 -,* &/7:.,+.#( +# D0&,*+ /#( +# &-,*$A&,*+ &., 'F3.'1(/4 , +# 2+31;&,*+

$(#:,1'.(/,E6 -,9(.(&µ,E6 /#( /,*9.,E1'6 /#( 7+# $(#:,1'.(/4 #/#$5 µ#Q/4 -'1(CA99,+ , +#

/A+,*+ +7,*6 :;9,*6 , +# µA8,*+ /#9E.'1# µ(# F7+5 29%&&# , /#( '/.46 #-4 49# #*.A µ#D; +#

7<,*+ -9015 #+#2+%1(&5 .3+ &-,*$%+ .,*6 4.#+ '-(&.17B,*+ &., K .T.M., 7<,*+ µ7&3 .,*

Erasmus .5+ /#9E.'15 '*/#(1;# +# -1#2µ#.,-,(0&,*+ #*.4 ., 4+'(1, .,*6 - /#( µA9(&.# , '/.46 #-4 .5+ *-,.1,:;# , #-#99A&&,+.#( #-4 .5+ *-,<173&5 /#.#C,906 $($A/.13+.

T1,b-,87&'(6 &*))'.,<06 .3+ :,(.5.%+ &., -1421#))#

U( :,(.5.76 -,* '+$(#:'1,+.#( +# &*))'.A&<,*+ &., -1421#))# -17-'(:" +# ';+#( :,(.5.76 /1A.,*6-)79,*6 .56 J.J. 0 A99,* /1A.,*6 -,* &*))'.7<'( &.,

-1421#))# SOCRATES.

" +# 7<,*+ ,9,/951%&'( ., -1%., 7.,6 .3+ &-,*$%+ .,*6.

" +# 2+31;D,*+ /#9A .5 29%&&# $($#&/#9;#6 .,* T#+'-(&.5);,* *-,$,<06

" +# -1,.;8'+.#( +# )'.#/(+58,E+ -1,/'()7+,* +# $(#+E&,*+ )(# ,9,/9513)7+5 -'1;,$,

.3+ &-,*$%+ .,*6 &., 'F3.'1(/4 (5 ,-,;# 8# -'1(9#)CA+'( /#( $(#$(/#&;# #F(,9425&56 .56

#/#$5)#Q/06 .,*6 '-;$,&56)

" +# -#1#/,9,*80&,*+ &., 'F3.'1(/4 )#80)#.# -,* ';+#( #+.;&.,(<# 0 (&,$E+#)# )'

)#80)#.# -,* -'1(9#)CA+,+.#( &., -1421#))# &-,*$%+ .,*6 &., K.T.M., %&.' +# ';+#( $*+#.0 5 #+#2+%1(&0 .,*6

H, K.T.M. '22*A.#( 15.A /#( '/ .3+ -1,.713+ 4.( 5 -'1;,$,6 &-,*$%+ &., 'F3.'1(/4 8#

#+#2+31(&.'; /#( 8# -1,&)'.158'; 2(# .5+ #-,+,)0 .,* -.*<;,*/$(-9%)#.,6/)'.#-.*<(#/,E

.;.9,*.

@(# -'1(&&4.'1'6 -951,:,1;'6 2(# ., -1421#))# SOCRATES/ERASMUS )-,1';.' +#

'-(&/':8';.' .5+ (&.,&'9;$# .56 J*13-#Q/06 J-(.1,-06:

http://europa.eu.int/comm/education/socrates.html

H, ERASMUS &., H)0)# ?,1(#/06 >(,9,2;#6 /#( @'+'.(/06

R. K(-93)#.(/76 J12#&;'6

O., -9#;&(, .,* - 1,21A))#.,6 Erasmus ., Hµ0 µ# ?,1(#/06 >(,9,2;#6 /#( @'+'.(/06

(H?>@), -#17<'( , #-4 ., #/#$5)#Q/4 7.,6 2004-2005, .5 $*+#.4.5.# &' .'.#1.,'.';6

:,(.5.76 .,* +# '/-,+0&,*+ .5 $(-93)#.(/0 .,*6 '12#&;# &' 7+# #-4 .# &*+'12#D4)'+# )' ., H?>@ J*13-#Q/A T#+'-(&.0)(#. U /#.A9,2,6 .3+ &*+'12#D,)7+3+ V$1*)A.3+ C1;&/'.#( &.5+ V&.,&'9;$# .,* H?>@.

>. H1(.,'.';6 :,(.5.76

O., -9#;&(, .,* -1,21A))#.,6 Erasmus ., H?>@ -#17<'( , #-4 ., #/#$5)#Q/4 7.,6 2010-

2011, .5 $*+#.4.5.# &' .1(.,'.';6 :,(.5.76 .,* +# '/-,+0&,*+ 7+# 'FA)5+, .3+ &-,*$%+

.,*6 &., H)0)# >(,9,2;#6 T#+'-(&.5);,* LE-1,*.

@. ?'.#-.*<(#/,; :,(.5.76

O., -9#;&(, .,* -1,21A))#.,6 Erasmus ., H?>@ , -#17<'( , #-4 ., #/#$5)#Q/4 7.,6 2010-

2011, .5 $*+#.4.5.# &' )'.#-.*<(#/,E6 :,(.5.76 .,* +# '/-,+0&,*+ 7+# 'FA)5+, .3+ &-,*$%+ .,*6 &.,:



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

194

University of Oxford, Department of Pharmacology.

K(#$(/#&;# '-(9,206 :,(.5.%+ 2(# &*))'.,<0 &., -1421#))# ERASMUS:

U( -1,-.*<(#/,; :,(.5.76 -,* '+$(#:71,+.#( +# &*))'.A&<,*+ &., -1421#))#

ERASMUS *-,CA99,*+ /#.A ., '#1(+4 'F#)5+, /#( )'.A #-4 -14&/95&5 .56 O*+.,+;&.1(#6 .,* -1,21A))#.,6 #;.5&5 '/$093&56 '+$(#:71,+.,6 -1,6 ., H)0)#.

I #;.5&5 &*+,$'E'.#( #-4:

i) OE+.,), C(,21#:(/4 &5)';3)#

ii) R+#9*.(/0 >#8),9,2;#

iii) T(&.,-,(5.(/4 F7+56 29%&&#6

RF(,9425&5

H '-(9,20 .3+ :,(.5.%+ -1#2)#.,-,(';.#( )' CA&5 .5 C#8),9,2;# .,*6 &E):3+# )' .#

/1(.01(# -,* 7<'( 87&'( 5 @'+(/0 O*+79'*&5 .,* H)0)#.,6 ?,1(#/06 >(,9,2;#6 /#( @'+'.(/06.

R. R+.#99#276 $(-93)#.(/%+ :,(.5.%+

I C#8),9,2;# .3+ *-,B5:;3+ C#&;D'.#( &.# #/49,*8# /1(.01(#:

1) )7&, 41, .56 C#8),9,2;#6 4-36 -1,/E-.'( #-4 .5+ #+#9*.(/0 C#8),9,2;# .,* *-,B5:;,*

(&*+.'9'&.06 0.5).

2) .5 &*+7+.'*F5 .,* *-,B5:;,* &.5+ J-(.1,-0 K(-93)#.(/%+ O-,*$%+ – 5 &*+7+.'*F5 -1#2)#.,-,(';.#( -#1,*&;# 4&3+ )'9%+ KJT .,* H?>@ '-(8*),E+ +# -#1#&.,E+

(&*+.'9'&.06 0.2).

3) .5+ -(&.,-,(5)7+5 2+%&5 .56 R229(/06 (&*+.'9'&.06 0.2).

4) .5+ -(&.,-,(5)7+5 2+%&5 .56 29%&&#6 .56 <%1#6 *-,$,<06 (&*+.'9'&.06 0.1).

5) .,+ #1(8)4 .3+ )#85)A.3+ -,* ,:';9'( , *-,B0:(,6. (#:#;1'&5 2(# /A8' )A85)# -,*

,:';9'( 0.2 ),+A$#6 #-4 .5+ .'9(/0 C#8),9,2;# -,* -1,/E-.'( #-4 .# 1-4).

K'+ 2;+,+.#( $'/.76 #(.0&'(6 *-,B5:;3+ .3+ ,-,;3+ , )7&,6 41,6 ';+#( )(/14.'1,6

#-4 7 0 ,:';9,*+ -#1#-A+3 #-4 5 )#80)#.#.

3. -9HAOOANI> S:FH8HP9

I C#8),9,2;# - #F(,9425&5 .3+ *-,B5:;3+ C#&;D'.#( &.# #/49,*8# /1(.01(#:1) )7&, 41, .56 C#8),9,2;#6 4-36 -1,/E-.'( #-4 .5+ #+#9*.(/0 C#8),9,2;# .,* *-,B5:;,*

(&*+.'9'&.06 0.5).

2) .5 &*+7+.'*F5 .,* *-,B5:;,* &.5+ J-(.1,-0 K(-93)#.(/%+ O-,*$%+ – 5 &*+7+.'*F5 -1#2)#.,-,(';.#( -#1,*&;# 4&3+ )'9%+ KJT .,* H?>@ '-(8*),E+ +# -#1#&.,E+

(&*+.'9'&.06 0.2).

3) .5+ -(&.,-,(5)7+5 2+%&5 .56 R229(/06 (&*+.'9'&.06 0.2).

4) .5+ -(&.,-,(5)7+5 2+%&5 .56 29%&&#6 .56 <%1#6 *-,$,<06 (&*+.'9'&.06 0.1).

5) .,+ #1(8)4 .3+ )#85)A.3+ -,* ,:';9'( , *-,B0:(,6. (#:#;1'&5 2(# /A8' )A85)# -,*

,:';9'( 0.2 ),+A$#6 #-4 .5+ .'9(/0 C#8),9,2;# -,* -1,/E-.'( #-4 .# 1-4).K'+ 2;+,+.#( $'/.76 #(.0&'(6 *-,B5:;3+ .3+ ,-,;3+ , )7&,6 41,6 ';+#( )(/14.'1,6



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

195

#-4 7 0 ,:';9,*+ -#1#-A+3 #-4 4 )#80)#.#.

9.3 J-(/,(+3+;#-T951,:,1;'6 2(# .o T1,21#))#:

" O.5 &*+.,+;&.1(# Erasmus .,* H)0)#.,6 , J-. L#8. O3.51;# ?-,*/,*CA9# , H)0)# ?,1(#/06

>(,9,2;#6 /#( @'+'.(/06 , L.;1(, 10, T#+'-(&.5)(,E-,95 , K1#2A+# , .59: 25510-30632, email:[email protected]

" O., @1#:';, K('8+%+ O<7&'3+/Socrates .,* T#+'-(&.5);,* (L.;1(, K(,;/5&56 , L,),.5+0 ,.59. 25310 39084, e-mail: [email protected])

" O.5+ (&.,87&5 .,* H)0)#.,6 http://mbg.duth.gr/.

9.4 +: !<JN<A77A !<ACHFCD> ERASMUS ("rasmus Placement)

H, T1421#))# T1#/.(/06 ERASMUS -1,&:71'( &.,*6 :,(.5.76 .5 $*+#.4.5.# +# '/-,+0&&,*+

T1#/.(/0 a&/5&5 &' :,1';6 .,* V$(3.(/,E /#( .,* K5)A&(,* H,)7# '+46 A99,* )79,*6 –

/1A.,*6 .56 J*13-#Q/06 N+3&56 0 &*+'12#D4)'+3+ <31%+.

!O8<:S:<@=> NFA Ho !<:N<A77A:

" O.5 &*+.,+;&.1(# Erasmus .,* H)0)#.,6 , J-. L#8. O3.51;# ?-,*/,*CA9# , H)0)# ?,1(#/06

>(,9,2;#6 /#( @'+'.(/06 , L.;1(, 10, T#+'-(&.5)(,E-,95 , K1#2A+# , .59: 25510-30632, email:

[email protected]" O., @1#:';, K('8+%+ O<7&'3+/Socrates .,* T#+'-(&.5);,* (L.;1(, K(,;/5&56 , L,),.5+0 ,.59. 25310 39084, e-mail: [email protected])


9.5 T1#/.(/0 a&/5&5

H, T1421#))# T1#/.(/06 a&/5&56 -1,&:71'( &.,*6 :,(.5.76 .5 $*+#.4.5.# '12#&.,E+ 2(#

.1'(6 )0+'6 &' :,1';6 .,* V$(3.(/,E /#( .,* K5)A&(,* H,)7# &.5 J99A$#.

!O8<:S:<@=> NFA Ho !<:N<A77A:

" O.5 &*+.,+;&.1(# Erasmus .,* H)0)#.,6 , /#. R(/#.'1;+5 L#.&A+5 , H)0)# ?,1(#/06

>(,9,2;#6 /#( @'+'.(/06 , L.;1(, 10, T#+'-(&.5)(,E-,95 , K1#2A+# , .59: 25510-30635, email:

[email protected]




!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

196

-44"1 )!/#"1$"1

1. 3FXOF:MDC8

I >(C9(,80/5 .,* H)0)#.,6 ?,1(#/06 >(,9,2;#6 & @'+'.(/06 .,* K.T.M , &*&.'2AD'.#( )'

.5 >(C9(,80/5 .,* H)0)#.,6 V#.1(/06 &' /.;1(, 1400m2 .56 T#+'-(&.5)(,E-,956 &.5 K1#2A+#.

H, /.;1(, $(#87.'( #+#2+3&.01(, , 4-,* ,( #+#2+%&.'6 )-,1,E+ +# <15&(),-,(,E+ ., *9(/4 .56

&*99,206 -,* $'+ $#+';D'.#(. H, *9(/4 #*.4 ,+,)AD'.#( -951,:,1(#/4 /#( -'1(9#)CA+'( .#

9'F(/A , .,*6 A.9#+.'6 , .# ABSTRACTS, ., V"DJ= ?JDICUS /#( .# -'1(,$(/A. K(#.;8'+.#( '-;&56

59'/.1,+(/,; *-,9,2(&.76 &*+$'$')7+,( &., K(#$;/.*, 2(# #+#D0.5&5 C(C9(,21#:;#6.K(/#(%)#.# $#+'(&),E C(C9;3+ 7<,*+ 49# .# )795 .56 T#+'-(&.5)(#/06 L,(+4.5.#6

#99A /#( )5 -#+'-(&.5)(#/,; 2(#.1,; , :#1)#/,-,(,; , +,&59'*.76 /#( 9,(-,; *2'(,+,)(/,;. U

$#+'(&)46 C(C9;3+ )-,1'; +# 2;+'( 2(# <1,+(/4 $(A&.5)# $*, 'C$,)A$3+. J-;&56 , &.5 >(C9(,80/5 *-A1<'( :3.,#+.(21#:(/4 )5<A+5)# /#( ,( :3.,.*-;'6 -#17<,+.#( $31'A+ 2(#

-'1(,1(&)7+, #1(8)4 &'9;$3+ *9(/,E .56 C(C9(,80/56. O*+,9(/A , 5 >(C9(,80/5 $(#87.'( 18000

.4),*6 C(C9;3+ , /#8%6 '-;&56 &*+$1,)76 &' 230 .;.9,*6 -'1(,$(/%+.

!-'E8*+,6 – >(C9(,85/,+4),6: L*1/,E$56 M'4$31,6.

H, 31A1(, 9'(.,*12;#6 .56 >(C9(,80/56 /#( .,* #+#2+3&.51;,* ';+#( 7:00 -.). )' 7:00).). K'*.71# 736 T#1#&/'*0 . T'1(&&4.'1'6 -951,:,1;'6 ,( '+$(#:'14)'+,( )-,1,E+ +#

#+#D5.0&,*+ &.# #/49,*8# .597:3+# /#( 59'/.1,+(/76 $('*8E+&'(6:

H597:3+, - Fax: 25510-30902

L'+.1(/0 >(C9(,80/5 : www.lib.duth.gr

>(C9(,80/5 V#.1(/06 ; www.lib.duth.gr/med

E-mail: [email protected]

2. 2<AS=@: EFABQ9G=B8>

H, @1#:';, K(#&E+$'&56 ($1E85/' .,+ U/.%C1(, .,* 1997 )' 7$1# .5+ ]A+85 , '+%

9'(.,*12,E+ $E, -#1#1.0)#.# &.5+ L,),.5+0 /#( & .5+ R9'F#+$1,E-,95 . I ;$1*&5 /#( 9'(.,*12;# .,* 7<,*+ 36 &.4<, +# C,580&,*+ .,*6 :,(.5.76 /#( #-4:,(.,*6 /A8' H)0)#.,6 +#

-1,&'22;&,*+ ,)#9A .5 )'99,+.(/0 .,*6 &.#$(,$1,);# , -#17<,+.#6 -951,:415&5 &<'.(/A )'

.(6 $*+#.4.5.'6 -,* .,*6 -1,&:71,+.#( .4&, /#.A .5 $(A1/'(# .3+ &-,*$%+ .,*6 4&, /#( )'.A .5 90B5 .,* -.*<;,* .,*6.

O*2/'/1()7+# , ., @1#:';, K(#&E+$'&56:

" T#17<'( -951,:,1;'6 2(# -1,-.*<(#/A /#( )'.#-.*<(#/A -1,21A))#.# '995+(/%+ /#( F7+3+ V$1*)A.3+ /#( 2(# *-,.1,:;'6 #-4 $(A:,1,*6 :,1';6 .



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

197

" K(,12#+%+'( $ (A:,1# &')(+A1(# '+5)713&56 #-4 -#+'-(&.5)(#/,E6 :,1';6 /#( &.'97<5 .,* -#1#232(/,E .,)7# '+5)'1%+'( .,*6 #-4:,(.,*6 2(# $(#87&()'6 87&'(6

'12#&;#6 /#( .,*6 -#17<'( &*)C,*9'*.(/0 *-,&.01(F5 &<'.(/A )' .5+ '-#22'9)#.(/0 .,*6

#-,/#.A&.#&5 .

@(# -'1(&&4.'1'6 -951,:,1;'6 .59. 25510 - 39235, ., ,-,;, 9'(.,*12'; /#( 36 FAX.

3. 2<A77AH=FACD )R:BHD<F58

I @1#))#.';# .,* H?>@ ';+#( *-'E8*+5 2(# .5+ -#1,<0 &.,*6 :,(.5.76 .3+ #/49,*83+

*-51'&(%+:

- 7/$,&5 C'C#(%&'3+ /#( -(&.,-,(5.(/%+.

- <,1025&5 :,(.5.(/06 .#*.4.5.#6. T14/'(.#( 2(# ., /E1(, '+$'(/.(/4 &.,(<';, -,* C'C#(%+'( .5+ :,(.5.(/0 ($(4.5.# /#( ';+#( #-#1#;.5.5 &.(6 'F'.A&'(6 /#( 2(# .5+ 7/$,&5 /A8' ';$,*6

-(&.,-,(5.(/,E.

- <,1025&5 C(C9(#1;,* *2'(,+,)(/06 -'1;8#9B56 )'.A #-4 #;.5&5 .,* :,(.5.0 .

I @1#))#.';# .,* H?>@ 9'(.,*12'; 2(# .5+ 'F*-517.5&5 .3+ :,(.5.%+ /#85)'1(+A #-4 .(6

11.00 -.) 736 .(6 13.00 ).).

H59. 25510 – 30612, 25510 – 30614, 25510 – 30610.

Fax: 25510- 30613

email:[email protected]



!"#"$ %&'($)#* +(&,&-.$* & /0102()#* 345 678-9* :;&<7=1 2013-2014

199

K*.(/A .56 -4956), /#( ,( V#)#.(/76 T5276 &.# Z,*.1A H1#Q#+,E-,956 (11 <9). R+#.,9(/A), .,

K79.# .,* NC1,* , ., KA&,6 .56 K#$(A6 /#( 5 #-#1A)(9956 ,),1:(A6 >*D#+.(+0 '//95&;# .56

T#+#2;#6 L,&),&%.51#6 -,* ($1E85/' ., 1151 #-4 .,+ V&#A/(, L,)+5+4 &.(6 G71'6.

5. %<DBF7A +8OIS?9A (,?GFCJ> CODB8> 25510)

-=<:OF7I9A> E/'&,#$+&1 45198

E87A<K@A 26410, 38409

E87:HFCD "RFK=@<8B8 +:L<FB7:Q 28735, 26055

,.+.".4 26479

4F7=9A<K=@: 26468

(:7A<K@A 36823

(:B:C:7=@: 25772

&.1.". 26398

+A5@ 27700, 27200, 27770

+:L<FBHFCD -BHL9:7@A 37411

Odigos Spoudon GR Final 13-14

Documents

Transcript of Odigos Spoudon GR Final 13-14