ACE inhibitor instead of β-blockers for better QOL in hypertension
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lO INTERNATIONAL RESEARCH & OPINION ACE inhibitor instead of P-blockers for better QOL in hypertension Replacing with captopril improves the quality of life (QOL) of patients with mild to moderate hypertension without compromising BP control. This was the conclusion of a study conducted by researchers at the Ben-Gurion University of Negev, Beer Sheva, Israel. The study included 133 patients (mean age 54 years) whose hypertension was well controlled by long-term treatment with atenolol or propranolol, with or without diuretics, and who had few adverse effects of treatment. Six to 15 months after randomisation to continue therapy (n = 80) or to change to captopril (53), captopril recipients reported improvements in all 6 areas of physical QOL. These improvements were significant compared with those reported by recipients in 4 areas (sleep, gastrointestinal symptoms, physical performance and cognitive function). Patients receiving captopril also experienced a greater increase in psychological well-being than those receiving they also had improved health perception whereas recipients experienced a decline in this area. Paran E. Anson 0, Neumann L. 1be effects of replacing beta-blockers with an angiotensin converting enzyme inhibitor on the quality of life of hypertensive patients. American Journal of Hypertension 9: 1206-1213, Part 1' Dec 1996 """"""' PharmacoEconomics & Outcomes News 25 Jan 1997 No. 96 1173-5503197/0096-0001 0/$01 .00° Ad is International Limited 1997. All rights rnerved
Transcript of ACE inhibitor instead of β-blockers for better QOL in hypertension
lO INTERNATIONAL RESEARCH & OPINION
ACE inhibitor instead of P-blockers for better QOL in hypertension
Replacing ~-blockers with captopril improves the quality of life (QOL) of patients with mild to moderate hypertension without compromising BP control. This was the conclusion of a study conducted by researchers at the Ben-Gurion University of Negev, Beer Sheva, Israel.
The study included 133 patients (mean age 54 years) whose hypertension was well controlled by long-term treatment with atenolol or propranolol, with or without diuretics, and who had few adverse effects of treatment.
Six to 15 months after randomisation to continue ~-blocker therapy (n = 80) or to change to captopril
(53), captopril recipients reported improvements in all 6 areas of physical QOL. These improvements were significant compared with those reported by ~-blocker recipients in 4 areas (sleep, gastrointestinal symptoms, physical performance and cognitive function). Patients receiving captopril also experienced a greater increase in psychological well-being than those receiving ~-blockers; they also had improved health perception whereas ~-blocker recipients experienced a decline in this area. Paran E. Anson 0, Neumann L. 1be effects of replacing beta-blockers with
an angiotensin converting enzyme inhibitor on the quality of life of hypertensive patients. American Journal of Hypertension 9: 1206-1213, Part
1 ' Dec 1996 """"""'
PharmacoEconomics & Outcomes News 25 Jan 1997 No. 96 1173-5503197/0096-0001 0/$01 .00° Ad is International Limited 1997. All rights rnerved
