![a -8 ≤ x < 3 [ -8 , 3 › b 4 < x ≤ 4½ ‹ 4 , 4½ ] c 5,1 ≤ x ≤ 7,3](https://static.fdocument.org/doc/165x107/56813ebe550346895da927e7/a-8-x-3-8-3-b-4-x-4-4-4-c-51-x-73.jpg)
a -8 ≤ x < 3 [ -8 , 3 › b 4 < x ≤ 4½ ‹ 4 , 4½ ] c 5,1 ≤ x ≤ 7,3
4-Chloro- a-PVP - SWGDRUGFTIRα-PVP HCl; Lot# RM-160311-01A ATR (Diamond 1 Bounce):...
5
4-Chloro- a -PVP The Drug Enforcement Administration's Special Testing and Research Laboratory generated this monograph using structurally confirmed reference material. Latest Revision: 9/6/2016 Page 1 of 5 SWGDRUG.org/monographs.htm 1. GENERAL INFORMATION IUPAC Name: 1-(4-chlorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one CAS#: NA Synonyms: 4-chloro-alpha-PVP Source: DEA Reference Material Collection Appearance: White powder UV max (nm): Not determined 2. CHEMICAL AND PHYSICAL DATA 2.1 CHEMICAL DATA Form Chemical Formula Molecular Weight Melting Point ( o C) Base C 15 H 20 ClNO 266 Not Determined HCl C 15 H 20 ClNO HCl 302 207.4 O N Cl CH 3
Transcript of 4-Chloro- a-PVP - SWGDRUGFTIRα-PVP HCl; Lot# RM-160311-01A ATR (Diamond 1 Bounce):...
4-Chloro- α -PVPThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 9/6/2016 Page 1 of 5SWGDRUG.org/monographs.htm
1. GENERAL INFORMATION
IUPAC Name: 1-(4-chlorophenyl)-2-(pyrrolidin-1-yl)pentan-1-one
CAS#: NA
Synonyms: 4-chloro-alpha-PVP
Source: DEA Reference Material Collection
Appearance: White powder
UVmax(nm): Not determined
2. CHEMICAL AND PHYSICAL DATA
2.1 CHEMICAL DATA
Form Chemical Formula Molecular Weight Melting Point (oC)
Base C15H20ClNO 266 Not Determined
HCl C15H20ClNO HCl 302 207.4
O
N
Cl
CH3
4-Chloro- α -PVPThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 9/6/2016 Page 2 of 5SWGDRUG.org/monographs.htm
3. QUALITATIVE DATA
3.1 NUCLEAR MAGNETIC RESONANCE
Sample Preparation: Dilute analyte to ~12 mg/mL in DMSO-d6 containing TMS for 0 ppm reference and 8drops CD3OD and dimethylfumarate as quantitative internal standard.
Instrument: 400 MHz NMR spectrometerParameters: Spectral width: at least containing -3 ppm through 13 ppm
Pulse angle: 90o
Delay between pulses: 45 seconds
1HNMR: 4-Chloro-α-PVP HCl; Lot# RM-160311-01A; 1 mL DMSO-d6 with 8 drops CD3OD; 400MHz
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4-Chloro- α -PVPThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 9/6/2016 Page 3 of 5SWGDRUG.org/monographs.htm
3.2 GAS CHROMATOGRAPHY/MASS SPECTROMETRY
Sample Preparation: Dilute analyte ~4 mg/mL in MeOH
Instrument: Agilent gas chromatograph operated in split mode with MS detectorColumn: HP-5 MS (or equivalent); 30m x 0.25 mm x 0.25 µmCarrier Gas: Helium at 1.5 mL/minTemperatures: Injector: 280oC MSD transfer line: 280oC
MS Source: 230oC MS Quad: 150oCOven program:
1) 100oC initial temperature for 1.0 min2) Ramp to 280oC at 12 oC/min3) Hold final temperature for 9.0 min
Injection Parameters: Split Ratio = 25:1, 1 µL injectedMS Parameters: Mass scan range: 30-550 amu Threshold: 150
Tune file: stune.u Acquisition mode: scanRetention Time: 11.208 min
EI Mass Spectrum: 4-Chloro-α-PVP HCl; Lot# RM-160311-01A
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4-Chloro-α-PVPThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Page 4 of 5Latest Revision: 9/6/2016 SWGDRUG.org/monographs.htm
Wavenumber (cm-1)4000 3500 3000 2500 2000 1500 1000
%Tr
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3.3 INFRARED SPECTROSCOPY (FTIR)
Insrument: FTIR with diamond ATR attachment (1 bounce)Scan Parameters: Number of scans: 32
Number of background scans: 32Resolution: 4 cm-1
Sample gain: 8Aperture: 150
FTIR ATR (Diamond 1 Bounce): 4-Chloro-α-PVP HCl; Lot# RM-160311-01A
4-Chloro-α-PVPThe Drug Enforcement Administration's Special Testing and Research Laboratory
generated this monograph using structurally confirmed reference material.
Latest Revision: 9/6/2016 Page 5 of 5SWGDRUG.org/monographs.htm
https://en.wikipedia.org/wiki/4-Chloro-alpha-pyrrolidinovalerophenone
4. ADDITIONAL RESOURCES
Wikipedia
![ΚΡΙΑΡΑ [4]-ΜΕΣΑΙΩΝΙΚΟ ΛΕΞΙΚΟ [4].pdf](https://static.fdocument.org/doc/165x107/563db816550346aa9a907265/-4-4pdf-568b999ed9931.jpg)
