Glycolysis

The three steps

Glucose + 2Pi +2ADP +2NAD

2Pyruvate + 2ATP +2NADH +2H+ +2H2O

Glucose to Glucose 6 phosphate

Hexokinase

G6P to F6P

Phosphohexose isomerase

Mg++

ΔG’O=1.7 kJ/mol

ΔG’o= -14.2 KJ/mol

F6P to F1,6, BP

F1,6BP to DHAP & G3P

ΔG’O = 23.8kJ/mol

DHAP & GAP

GAP to 1,3-BPG

ΔG’O = 6.3kJ/mol

1,3-BPG to 3-PG

ΔG’O = -18.5kJ/mol

3’PG to 2’PG

Rearrangement shifts PO4 position from C3 to C2.

2PG to PEP

Enol PO4

PEP to Pyruvate

Thermodynamics

Uses of Pyruvate

Regeneration of NAD

Pyruvate to ethanol

Pyruvate to lactate

Recycling NAD

Xxxxxxxx

Galactose

Glycogen to glucose (starvation)

xxxxx