Alpha-synuclein contributes to malignant progression of ... Alpha-synuclein contributes to malignant Documents

Large α-synuclein oligomers inhibit neuronal SNARE ... · main of synaptobrevin-2, which blocks the docking between vesi-cles. In contrast, the α-Syn monomer presents no appreciable Documents

Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking Bong-Kyu Choia1 Mal-Gi Choib1 Jae-Yeol Kimc1 Yoosoo Yangbd Ying Laie Dae-Hyuk Kweond Nam Ki Leeac2…

In vivo visualization of propagating α-synuclein pathologies in ......2020/10/23 · further analyzed with a tissue microarray in our latest work (Miranda-Azpiazu et al., 2020). Documents

1 In vivo visualization of propagating α-synuclein pathologies in mouse and marmoset models by a bimodal imaging probe C05-05 AUTHORSAFFILIATIONS Maiko Ono13* Manami Takahashi13…

Interaction between Parkin and -Synuclein in PARK2 ......biogenesis. PARK2-related PD is generally thought not to be associated with Lewy body formation although it is a neuropathological Documents

cells Review Interaction between Parkin and α-Synuclein in PARK2-Mediated Parkinson’s Disease Daniel Aghaie Madsen 1, Sissel Ida Schmidt 1, Morten Blaabjerg 1,2,3,4 and…

Comparative analyses of the in vivo induction and transmission of … · pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils Jess-Karan S. Dhillon1,2, Documents

RESEARCH Open Access Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein…

Effects of impaired membrane interactions on α-synuclein ... · Received 21 January 2015 Revised 20 April 2015 Accepted 21 April 2015 Available online 27 April 2015 Keywords: Aggregation Documents

Neurobiology of Disease 79 2015 150–163 Contents lists available at ScienceDirect Neurobiology of Disease j ourna l homepage: wwwe lsev ie r com locate ynbd i Effects of…

Nuclear Magnetic Resonance Observation of α Synuclein ... · PDF fileprotein and lipid membranes is key to its role in synaptic ... complexes or for individual proteins.1 At a more Documents

Nuclear Magnetic Resonance Observation of α‑Synuclein Membrane Interaction by Monitoring the Acetylation Reactivity of Its Lysine Side Chains Jung Ho Lee, Jinfa Ying,…

Evidence for -synuclein prions causing multiple …...leads to death in 10–20 y. MSA has been subdivided based on the predominance of Parkinson’s symptoms (MSA-P) or cerebellar Documents

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism Stanley B Prusinerabc1 Amanda L Woermana Daniel A Mordesd Joel C Wattsab2 Ryan…

Probing the interaction between -synuclein and lipid membranes … · 2014. 12. 15. · membrane-bound and unbound states. The N-terminal segment of ca 25 residues adopts a well-defined, Documents

Probing the interaction between α-synuclein and lipid membranes by NMR Spectroscopy Giuliana Fusco Alfonso De Simone† Gopinath Tata§ Vitaly Vostricov § Michele Vendruscolo…

fibrillation of α-Synuclein in vitroAcoustic alternate current (AAC) mode AFM was performed using a Pico Plus 5500 AFM (Agilent Technologies, USA) with a piezoscanner having a maximum Documents

SUPPORTING INFORMATION An aminoglycoside antibiotic inhibits both lipid-induced and solution-phase fibrillation of α-Synuclein in vitro Anindita Mahapatraa,b, Sukanya Sarkarc,…

The making of a Lewy body: the role of α-synuclein post ... · Graham Knott7, Georges Mairet-Coello8, Laura Weerens1,8, Anne Michel8, Patrick Downey8, Martin Citron8 and Hilal A. Documents

1 The making of a Lewy body: the role of α-synuclein post-fibrillization modifications in regulating the formation and the maturation of pathological inclusions. Anne-Laure…

Induction of de novo α-synuclein fibrillization in a ... · part due to the lack of animal models recapitulating α-Syn fibrillization into LB-like inclusions in the brain. Because Documents

Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease Mohamed-Bilal Faresa Bohumil Macoa Abid Oueslatia1 Edward Rockensteinb Natalia…

Poly (ADP-ribose) induces α-synuclein aggregation in ... · (Fig. 1e, Extended Data Fig. 1c) and noted an increase in band intensity for a higher molecular weight form of αSyn (~ Documents

1 Poly ADP-ribose induces α-synuclein aggregation in neuronal-like cells and interacts with phosphorylated α-synuclein in post mortem PD samples Laura N Puentes 1 Zsofia…

Role of cytochrome c in α-synuclein radical formation ... · by combined exposure to the fungicide Maneb (manga-nese ethylene-1,2-bisdithiocarbamate) and the herbicide paraquat (1,1-dimethyl-4,4-bipyridinium) Documents

Kumar et al. Molecular Neurodegeneration 2016 11:70 DOI 10.1186s13024-016-0135-y RESEARCH ARTICLE Open Access Role of cytochrome c in α-synuclein radical formation: implications…

€¦ · 20/11/2019 · 1 Title: Doublecortin like kinase 1 regulates D-Synuclein levels and toxicity 2 3 Abbreviated title: DCLK1 regulates D -Syn levels 4 5 Gabriel E. Vázquez-Vélez Documents

A dual role for α-synuclein in facilitation and depression ... · pars compacta (Fig. 1 G and H). To analyze the spontaneous in vivo activity of these neurons during the anesthesia, Documents

A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo Mahalakshmi Somayajia,b, Stefano Cataldia,b, Se…

Human α-Synuclein Kit/media/files/product inserts...Reagent Storage Catalog # Size Quantity Supplied Description 1 Plate Kit 5 Plate Kit 25 Plate Kit MULTI-SPOT® 96- well 4-spot Documents

18097-v1-2013Jul 1 Human α-Synuclein Kit 1-Plate Kit K151TGD-1 5-Plate Kit K151TGD-2 25-Plate Kit K151TGD-4 18097-v1-2013Jul 2 MSD Neurodegenerative Disease Assays Human…

In Silico Study of the Mechanism of Binding of the N-Terminal … · 2020. 6. 26. · N-Terminal Region of Synuclein to Synaptic-Like Membranes Carlos Navarro-Paya 1, Maximo Sanz-Hernandez Documents

In Silico Study of the Mechanism of Binding of the N-Terminal Region of Synuclein to Synaptic-Like Membraneslife Article In Silico Study of the Mechanism of Binding of the

Transfer of human α‑synuclein from the olfactory bulb to … · 2017. 8. 26. · 3 h after injection of unbound ATTO-550 or Alexa-488 (dissolved in PBS) into the OB of mice. The Documents

1 3 Acta Neuropathol 2013 126:555–573 DOI 10.1007s00401-013-1160-3 OrIgINAl PAPer Transfer of human α‑synuclein from the olfactory bulb to interconnected brain regions…

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