TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired...

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TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer Mary Chitilian, Majdina Isovic, Jailal Nicholas George Ablack, Joe Stephen Mymryk, Marc Tini, Joseph Torchia Molecular Cell Volume 46, Issue 5, Pages 636-649 (June 2012) DOI: 10.1016/j.molcel.2012.03.027 Copyright © 2012 Elsevier Inc. Terms and Conditions

Transcript of TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired...

Page 1: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex 

Gobi Thillainadesan, Jennifer Mary Chitilian, Majdina Isovic, Jailal Nicholas George Ablack, Joe Stephen Mymryk, Marc Tini, Joseph Torchia 

Molecular Cell Volume 46, Issue 5, Pages 636-649 (June 2012)

DOI: 10.1016/j.molcel.2012.03.027

Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 2: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 1

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 3: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 2

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 4: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 3

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 5: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 4

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 6: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 5

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 7: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 6

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions

Page 8: TGF-β-Dependent Active Demethylation and Expression of the p15ink4b Tumor Suppressor Are Impaired by the ZNF217/CoREST Complex Gobi Thillainadesan, Jennifer.

Figure 7

Molecular Cell 2012 46, 636-649DOI: (10.1016/j.molcel.2012.03.027) Copyright © 2012 Elsevier Inc. Terms and Conditions