Synthesis of Enantiopure Pyrrolidine-Derived Peptidomimetics and Oligo-β-Peptides via Nucleophilic...

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2006 Peptides U 0400 Synthesis of Enantiopure Pyrrolidine-Derived Peptidomimetics and Oligo-β-Pep- tides via Nucleophilic Ring-Opening of β-Lactams. — (MACIAS, A.; RAMALLAL, A. M.; ALONSO, E.; DEL POZO, C.; GONZALEZ*, J.; J. Org. Chem. 71 (2006) 20, 7721-7730; Dep. Quim. Org. Inorg., Fac. Quim., Univ. Oviedo, E-33071 Oviedo, Spain; Eng.) — Lindner 52- 198

Transcript of Synthesis of Enantiopure Pyrrolidine-Derived Peptidomimetics and Oligo-β-Peptides via Nucleophilic...

Page 1: Synthesis of Enantiopure Pyrrolidine-Derived Peptidomimetics and Oligo-β-Peptides via Nucleophilic Ring-Opening of β-Lactams.

2006

PeptidesU 0400 Synthesis of Enantiopure Pyrrolidine-Derived Peptidomimetics and Oligo-β-Pep-

tides via Nucleophilic Ring-Opening of β-Lactams. — (MACIAS, A.; RAMALLAL, A. M.; ALONSO, E.; DEL POZO, C.; GONZALEZ*, J.; J. Org. Chem. 71 (2006) 20, 7721-7730; Dep. Quim. Org. Inorg., Fac. Quim., Univ. Oviedo, E-33071 Oviedo, Spain; Eng.) — Lindner

52- 198

Reactions of haloalkanes.. Nucleophilic substitution Halogens are relatively electronegative. So the carbon/halogen bond will be polarised. δ-δ- δ+δ+

Reactions of haloalkanes.. Nucleophilic substitution Halogens are relatively electronegative. So the carbon/halogen bond will be polarised. δ-δ- δ+δ+

δ X δ electrophilic site C - Yonsei University€¦ · Ch.11 Nucleophilic Substitutions and Eliminations 11.1 The Discovery of Walden Inversion In 1896, Walden discovered pure enantiomeric

δ X δ electrophilic site C - Yonsei University€¦ · Ch.11 Nucleophilic Substitutions and Eliminations 11.1 The Discovery of Walden Inversion In 1896, Walden discovered pure enantiomeric

Α,β-Unsaturated Carbonyl Compounds. α,β-Unsaturated Carbonyl Compounds, reactions: 1.electrophilic addition deactivated 2.nucleophilic addition activated.

Α,β-Unsaturated Carbonyl Compounds. α,β-Unsaturated Carbonyl Compounds, reactions: 1.electrophilic addition deactivated 2.nucleophilic addition activated.

Caractérisation de la structure primaire des …ddata.over-blog.com/xxxyyy/3/94/58/78/TD_Bioch7_support...2 3 Analyse de la structure primaire des oligo- et poly-saccharides Rappels

Caractérisation de la structure primaire des …ddata.over-blog.com/xxxyyy/3/94/58/78/TD_Bioch7_support...2 3 Analyse de la structure primaire des oligo- et poly-saccharides Rappels

Nucleophilic Substitution and Elimination Reactions of ...

Nucleophilic Substitution and Elimination Reactions of ...

Novel heteroleptic -(CN) Pd(II) chelates for the ... · Supplementary Material ESI 1 Novel heteroleptic cis-(C∧N) 2Pd(II) chelates for the preparation of enantiopure planar chiral

Novel heteroleptic -(CN) Pd(II) chelates for the ... · Supplementary Material ESI 1 Novel heteroleptic cis-(C∧N) 2Pd(II) chelates for the preparation of enantiopure planar chiral

Kinetic Resolution of Chiral α-Olefins Using Enantiopure ... · Kinetic Resolution of Chiral α-Olefins Using Enantiopure Ziegler-Natta Polymerization Catalysts Thesis by Endy Yeo-Jung

Kinetic Resolution of Chiral α-Olefins Using Enantiopure ... · Kinetic Resolution of Chiral α-Olefins Using Enantiopure Ziegler-Natta Polymerization Catalysts Thesis by Endy Yeo-Jung

Chapter 17: Aldehydes and Ketones: Nucleophilic Addition ...€¦ · 2. Reduction to 1° and 2° alcohols (Chapter 15.2) 3. Addition of Grignard Reagents (Chapters 14.5-14.6) 120

Chapter 17: Aldehydes and Ketones: Nucleophilic Addition ...€¦ · 2. Reduction to 1° and 2° alcohols (Chapter 15.2) 3. Addition of Grignard Reagents (Chapters 14.5-14.6) 120

CH. 20 - CARBOXYLIC ACID DERIVATIVES: NASlightcat-files.s3.amazonaws.com/packets/admin_organic-2...CONCEPT: COOH DERIVATIVES AND NUCLEOPHILIC ACYL SUBSTITUTION Carboxylic acid derivatives

CH. 20 - CARBOXYLIC ACID DERIVATIVES: NASlightcat-files.s3.amazonaws.com/packets/admin_organic-2...CONCEPT: COOH DERIVATIVES AND NUCLEOPHILIC ACYL SUBSTITUTION Carboxylic acid derivatives

JECRC UNIVERSITY CHEMISTRY : PAPER - I INORGANIC … Chemistry.pdf · Nomenclature & classes of alkyl halides, methods of formation, chemical reaction. Mechanism of nucleophilic substitution

JECRC UNIVERSITY CHEMISTRY : PAPER - I INORGANIC … Chemistry.pdf · Nomenclature & classes of alkyl halides, methods of formation, chemical reaction. Mechanism of nucleophilic substitution

Asymmetric synthesis of -(heteroaryl)alkylamines and -amino … · Asymmetric synthesis of -(heteroaryl)alkylamines and -amino acids via nucleophilic 1,2-addition of lithiated heterocycles

Asymmetric synthesis of -(heteroaryl)alkylamines and -amino … · Asymmetric synthesis of -(heteroaryl)alkylamines and -amino acids via nucleophilic 1,2-addition of lithiated heterocycles

Homologation chemistry with nucleophilic α-substituted ...

Homologation chemistry with nucleophilic α-substituted ...

π-extended oligo(imidazole)s and their hydrogen-bonded ......imidazole-rings, which have two-direction interaction sites, can form the H-bonds and coordination bonds directed to both

π-extended oligo(imidazole)s and their hydrogen-bonded ......imidazole-rings, which have two-direction interaction sites, can form the H-bonds and coordination bonds directed to both

Prepared by : Dr.Narmin Hussen Assistance lecture 3.pdfthe strained lactam ring, particularly to hydrolysis. • the B-lactam carbonyl group of penicillin readily undergoes nucleophilic

Prepared by : Dr.Narmin Hussen Assistance lecture 3.pdfthe strained lactam ring, particularly to hydrolysis. • the B-lactam carbonyl group of penicillin readily undergoes nucleophilic

Nucleophilic Aliphatic Substitution - Purdue University€¦ ·  · 2006-11-20One feature of nucleophilicity - the “α effect” ... Neighboring Group Effects: nucleophilic substitution

Nucleophilic Aliphatic Substitution - Purdue University€¦ ·  · 2006-11-20One feature of nucleophilicity - the “α effect” ... Neighboring Group Effects: nucleophilic substitution

Supporting Information - PNAS · MAGE oligo sets of varying complexity (minimum: 7, maximum: 14) such that a single marker (tolC) could be inserted at most 564,622 bp upstream relative

Supporting Information - PNAS · MAGE oligo sets of varying complexity (minimum: 7, maximum: 14) such that a single marker (tolC) could be inserted at most 564,622 bp upstream relative

RSC eBook Collection · 2009. 8. 7. · Cozzi and Zoli Nucleophilic substitution of ferrocenyl alcohols 1463-9262(2007)9:12;1-R RSC eBook Collection Access and download existing and

RSC eBook Collection · 2009. 8. 7. · Cozzi and Zoli Nucleophilic substitution of ferrocenyl alcohols 1463-9262(2007)9:12;1-R RSC eBook Collection Access and download existing and

Supporting Information - rsc.org filedecompose and release dinitrogen, acetone and carbene 12.1 In Pathway A, nucleophilic addition of in situ generated 12 to the C=O bond would generate

Supporting Information - rsc.org filedecompose and release dinitrogen, acetone and carbene 12.1 In Pathway A, nucleophilic addition of in situ generated 12 to the C=O bond would generate

Chapter 11ocw.snu.ac.kr/sites/default/files/NOTE/OC2-w01-Ch11.pdf · 2019. 3. 18. · reacts like a carbanion C: – ~ a C Nu: reactions as C Nu: (like S. N (2)) nucleophilic addition

Chapter 11ocw.snu.ac.kr/sites/default/files/NOTE/OC2-w01-Ch11.pdf · 2019. 3. 18. · reacts like a carbanion C: – ~ a C Nu: reactions as C Nu: (like S. N (2)) nucleophilic addition

Application of nucleophilic fluorinating reagents for the synthesis …doktori.bibl.u-szeged.hu/10076/3/RAM_tézisfüzet_EN_2.3.pdf · 2019-02-13 · Recent advances in the transformations

Application of nucleophilic fluorinating reagents for the synthesis …doktori.bibl.u-szeged.hu/10076/3/RAM_tézisfüzet_EN_2.3.pdf · 2019-02-13 · Recent advances in the transformations