Supplemental Figure 7. AKAP12 protein expression correlates with the AKAP12 promoter methylation status in glioma cell lines. AKAP12 immunocytochemistry of FFPE glioma cell lines is depicted. Glioma cell lines with high AKAP12α promoter methylation levels (LN-18 is shown as an example of this group) present with marked lower AKAP12 protein expression levels as compared to a strong AKAP12 protein expression seen in glioma cells with considerably lower AKAP12α promoter methylation status (U87MG is shown as an example of this group).