Karlijn van Aerde

Two independent cortical subnetworks control spike timing of layer 5 pyramidal neurons

during dynamic β oscillation shifts

Karlijn van Aerde et al, VU University Amsterdam

Fast network oscillations (beta range) are dynamic!

- in rat brain slices

- in awake rats

- in human EEG

What is the underlying network? Or should I say… networks!

Adrien Peyrache

Time Course of Reactivation in the Prefrontal cortexAdrien Peyrache, K. Benchenane, S Wiener, F Battaglia

Arrival

Sleep PRE

Sleep POSTTime (s)

Time (s)

Fre

qu

en

cy

(H

z)F

req

ue

nc

y (

Hz)

Recordings

LFP

Recordings

LFP, Spikes

PFCHippocampus

Sleep POST

Sleep PRE

1st PC

coefficient

delta/spindles events

freq

uen

cy (

Hz)

reactivation

measu

reHippocampal

filtered LFP

(100-300 Hz)

cells ensemble

activity

Iris Grothe

Attentional modulation of coherence between monkey area V1 and V4

Iris GrotheBernstein Group for Computational Neurosciences BremenGermany

160

117

85

62

45

33

24

18

0 2 4 6 0 2

160

117

85

62

45

33

24

18

0.25

0.20

0.15

0.10

0.05

0.25

0

0.0005

0.005

0.05

0.5

0

160

117

85

62

45

33

24

18

0 2 4 6Time (s)

Fre

quen

cy (

Hz)

Coherence P-value

Attentional modulation of coherence between monkey area V1 and V4

Iris GrotheBernstein Group for Computational Neurosciences BremenGermany

Alexander Hanuschkin

Magteld Zeitler

Michiel Remme

Paolo Bonifazi

0 40002000 300010000

0.2

0.4

0

100

200

Frac

tion

Cell

(#)

Time (frames)

IDENTIFICATION OF CELLULAR NETWORK HUBS DRIVING OSCILLATIONS IN THE DEVELOPING HIPPOCAMPUS

0

50

100

150

200

970 975 980 985 990 995 10000

0.2

0.4

Recording and “perturbation” of cells partecipating in build up of network synchrony

Frac

tion

of c

ells

0

0.05

0.1

0.15

0.2

0 pA

+40 pA

-75 mV-45 mV

Cell-network interaction

200 µm

oo

200 µm

Morphology

Perturbating Not perturbating

Network topology(based on functional connectivity)

P. Bonifazi - M. GoldinY. Ben-AriR. Cossart

INMED, Marseille (France)

David Chik

Synchronization model Synchronization model of multi-stable of multi-stable perceptions perceptions

Saskia Haegens

Oscillatory brain activity during human somatosensory working memory maintenance

What is the role of primary and secondary sensory regions in working memory?Which oscillations are involved?

MEG, median nerve stimulation, delayed-match-to-sample task:

SII

SI

Primary somatosensory cortex (SI)

Saskia HaegensF.C. Donders Centre for Cognitive Neuroimaging

April 21, 2023

Oscillatory brain activity during human somatosensory working memory maintenance

alpha ↑

alpha ↓

gamma ↑

gamma ↑

gamma ↑

Main conclusions: Sustained gamma band activity reflects working memory maintenance;

first in SI and then bilaterally in SII. Alpha band activity reflects functional inhibition of task-irrelevant regions.