Interferon-β-1b

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Reactions 1471, p28 - 28 Sep 2013 S Interferon-β-1b Autoimmune polyendocrine syndrome: case report A 37-year-old man with multiple sclerosis and Grave’s disease was diagnosed with autoimmune polyendocrine syndrome type 3, after developing type 1 diabetes mellitus while receiving interferon-β-1b [dosage, route and duration of therapy to onset of reaction, and outcome not stated]. Author comment: "In our patient, type 1 diabetes mellitus seemed to be induced by restarting interferon-β-1b therapy. Our case suggested that. . . interferon-β-1b therapy for an MS patient with a specific genetic background may induce onset of type 1 diabetes mellitus." Masuda S, et al. Autoimmune polyendocrine syndrome type 3 with multiple sclerosis: Possible induction of type 1 diabetes by interferon-b1b therapy. Clinical and Experimental Neuroimmunology 4: 134, No. 1, Jun 2013. Available from: URL: http://dx.doi.org/10.1111/cen3.12004 [abstract] - Japan 803093278 1 Reactions 28 Sep 2013 No. 1471 0114-9954/13/1471-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved

Transcript of Interferon-β-1b

Page 1: Interferon-β-1b

Reactions 1471, p28 - 28 Sep 2013

SInterferon-β-1b

Autoimmune polyendocrine syndrome: case reportA 37-year-old man with multiple sclerosis and Grave’s

disease was diagnosed with autoimmune polyendocrinesyndrome type 3, after developing type 1 diabetes mellituswhile receiving interferon-β-1b [dosage, route and duration oftherapy to onset of reaction, and outcome not stated].

Author comment: "In our patient, type 1 diabetes mellitusseemed to be induced by restarting interferon-β-1b therapy.Our case suggested that. . . interferon-β-1b therapy for an MSpatient with a specific genetic background may induce onsetof type 1 diabetes mellitus."Masuda S, et al. Autoimmune polyendocrine syndrome type 3 with multiplesclerosis: Possible induction of type 1 diabetes by interferon-b1b therapy. Clinicaland Experimental Neuroimmunology 4: 134, No. 1, Jun 2013. Available from:URL: http://dx.doi.org/10.1111/cen3.12004 [abstract] - Japan 803093278

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Reactions 28 Sep 2013 No. 14710114-9954/13/1471-0001/$14.95 Adis © 2013 Springer International Publishing AG. All rights reserved