GDC-0941
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GDC- 0941 ZSTK474 Control NVP- BEZ235 CDDP Paclitax el SN-38 Control 24h 48h 48h 54.6% 91.5% 89.6% 93.2% 59.3% 88.3% 89.8% 91.7% 56.4% 32.1% 33.7% 20.0% Fig. S1
description
Fig. S1. 54.6%. 91.5%. 89.6%. 93.2%. 59.3%. 88.3%. 89.8%. 91.7%. 56.4%. 32.1%. 33.7%. 20.0%. Control. ZSTK474. GDC-0941. NVP-BEZ235. 24h. 48h. Control. Paclitaxel. SN-38. CDDP. 48h. Fig. S2. control. ZSTK. GDC. NVP. Time (h). 0. 24. 48. 24. 48. 24. 48. 24. 48. - PowerPoint PPT Presentation
Transcript of GDC-0941
GDC-0941 ZSTK474Control NVP-BEZ235
CDDP PaclitaxelSN-38Control
24h
48h
48h
54.6% 91.5% 89.6% 93.2%
59.3% 88.3% 89.8% 91.7%
56.4% 32.1% 33.7% 20.0%
Fig. S1
Phospho-4E-BP1
Phospho-S6
ZSTK GDC NVP
24 48 24 48 24 4824 480
control
Phospho-Akt
Phopho-Rb
Cleaved PARP
P.C
.
Fig. S2
Time (h)
Fig. S3
P-S6
P-Rb
CleavedPARP
100μm
ZSTK474Control ZSTK474Control
6
5
4
3
2
1
0SK-OV3PC-3
ControlZSTK474
Rela
tive
tum
or s
ize
A
B PC-3 SK-OV3
control ZSTK474
0h
12h
24h
72h
Cell size(FSC-H)
DN
A co
nten
t(F
L2A)
Fig. S4
