ChemInform Abstract: Preparation of Polysubstituted Piperidines via Radical Cyclization.
1
2000 pyridine derivatives pyridine derivatives R 0380 42 - 123 Preparation of Polysubstituted Piperidines via Radical Cyclization. — Title compounds are prepared by intramolecular cycloaddition of unstable α-aminoalkyl radicals [generated from (III)] to unactivated double bonds. When an aryl group is attached to the α-aminoalkyl moiety as in compound (IX), [1,2]-aza-Wittig rearrangement occurs as main reaction instead of cyclization. This latter rearrangement type is further studied, using amines (XII) as starting compounds. — (KATRITZKY, ALAN R.; LUO, ZHUSHOU; FANG, YUN- FENG; FENG, DAMING; GHIVIRIGA, ION; Perkin 2 (2000) 7, 1375-1380; Cent. Heterocycl. Comp., Dep. Chem., Univ. Fla., Gainesville, FL 32611, USA; EN) 1
-
Upload
alan-r-katritzky -
Category
Documents
-
view
218 -
download
2
Transcript of ChemInform Abstract: Preparation of Polysubstituted Piperidines via Radical Cyclization.
2000 pyridine derivatives
pyridine derivativesR 0380
42 - 123Preparation of Polysubstituted Piperidines via Radical Cyclization.— Title compounds are prepared by intramolecular cycloaddition of unstableα-aminoalkyl radicals [generated from (III)] to unactivated double bonds. Whenan aryl group is attached to the α-aminoalkyl moiety as in compound (IX),[1,2]-aza-Wittig rearrangement occurs as main reaction instead of cyclization.This latter rearrangement type is further studied, using amines (XII) as startingcompounds. — (KATRITZKY, ALAN R.; LUO, ZHUSHOU; FANG, YUN-FENG; FENG, DAMING; GHIVIRIGA, ION; Perkin 2 (2000) 7, 1375-1380;Cent. Heterocycl. Comp., Dep. Chem., Univ. Fla., Gainesville, FL 32611,USA; EN)
1
![Transannular Cyclization of Dehydrobenzo[12]annulene Induced by Nucleophilic Attack Tobe Lab Ayumi Yoshizaki 1.](https://static.fdocument.org/doc/165x107/56649cd75503460f9499f67b/transannular-cyclization-of-dehydrobenzo12annulene-induced-by-nucleophilic.jpg)
