NeedsContributesLacks Mother Placenta Fetus Progesterone LDL Cholesterol Adequate synthetic capacity...

Post on 01-Apr-2015

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Transcript of NeedsContributesLacks Mother Placenta Fetus Progesterone LDL Cholesterol Adequate synthetic capacity...

Needs Contributes Lacks

Mother

Placenta

Fetus

Progesterone LDL Cholesterol Adequate synthetic capacityEstrone (for progesterone and estrogens)EstradiolEstriol

3β-hydoxysteroid dehydrogenase(3β-HSD)Aromatase (P-450arom)

Adequate cholesterol capacity17α-hydroxylase (for estrone and estradiole synthesis)17,20-desmolase(for estrone and estradiole synthesis)16α-hydoxylase(for estriol synthesis)

17α-hydroxylase (for estrone and estradiole synthesis)17,20-desmolase(for estrone and estradiole synthesis)16α-hydoxylase(for estriol synthesis)

3β-hydoxysteroid dehydrogenase(3β-HSD)Aromatase (P-450arom)