ChemInform Abstract: Practical, Asymmetric Synthesis of Aromatic-Substituted Bulky and Hydrophobic...

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Transcript of ChemInform Abstract: Practical, Asymmetric Synthesis of Aromatic-Substituted Bulky and Hydrophobic...

2002 amino acids, peptides

amino acids, peptidesU 0400

03 - 193Practical, Asymmetric Synthesis of Aromatic-Substituted Bulky andHydrophobic Tryptophan Derivatives. — The synthesis of tryptophanderivatives (VIII) is based on the highly enantioselective catalytic hydrogenationof the α-enamide (V) and a subsequent Suzuki cross-coupling. — (WANG,WEI; XIONG, CHIYI; YANG, JIANQING; HRUBY, VICTOR J.; TetrahedronLett. 42 (2001) 44, 7717-7719; Dep. Chem., Univ. Ariz., Tucson, AZ 85721,USA; EN)

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