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When your child is too sweet By Dr Liaw Siew Ching * IDDM/ Type I DM Introduction Physiology of diabetes in β cell failure in type 1 DM DKA Long term management of diabetes…

Diabetes Mellitus Type II Beta Cell Failure in DM T2 signaling pathways implicated in β-cell failure Wnt Signaling Pathway Controls organismal growth and differentiation…

DIABETES MANAGEMENT Naushira Pandya, MD, CMD, FACP Professor and Chair, Department of Geriatrics Director, Geriatrics Education Center Nova Southeastern University Kiran…

Immunotherapies currently in development for the treatment of type 1 diabetes Ian C Davis, Jacqueline Randell & Stephen N Davis Expert Opinion on Investigational Drugs,…

1.Insulins in Type 2 DiabetesMellitus Dr. Sharat S. Kolke MD, DNB2. WhenWhyHow? 3. Serum Insulin levelEndogenous insulin Time (hrs)Dynamic nature of normal endogenous insulin…

The Journal of Clinical Investigation R E V I E W 1 jciorg Volume 127 Number 8 August 2017 Introduction Type 1 diabetes T1D is a chronic autoimmune disease resulting in severe…

Diagnosing Diabetes Mellitus in Adults: Type 1, LADA, Type 2: Rationale and Implications of a β-Cell- Centric Classification of Diabetes Stanley Schwartz MD, FACE, FACP…

Treatment of type 1 diabetes via α-cell insulin production Bertozzi Alessia Buccioli Lucia Tosato Federica Gene Therapy Professor Isabella Saggio A.Y. 20182019 Background…

Type 2 Diabetes – 2010 Robert J. Rushakoff, MD Professor of Medicine University of California, San Francisco robert.rushakoff@ucsf.edu Hyperglycemia β ⇑⇑⇑⇑ hepatic…

DOI: 10.1530JOE-16-0021 Jo u rn al o f En d o cr in o lo g y http:joe.endocrinology-journals.org 2016 Society for Endocrinology Printed in Great Britain Published by Bioscientifica…

Advancing Type 2 Diabetes Care With Modern Insulins Advancing Type 2 Diabetes Care With Modern Insulins Goals Type 2 Diabetes Is Progressive Most Patients Are Not Achieving…

Type 2 diabetes via β-cell dysfunction in East Asian people Jeong Hyun Park MD PhD Department of Internal Medicine Busan Paik Hospital College of Medicine Inje University…

Diagnosing Diabetes Mellitus in Adults: Type 1, LADA, Type 2: Rationale and Implications of a β-Cell- Centric Classification of Diabetes Stanley Schwartz MD, FACE, FACP…

PTPN2 regulates cytokine-induced β-cell death PTPN2 a candidate gene for type 1 diabetes modulates interferon-gamma- induced pancreatic beta-cell apoptosis Running title:…

REVIEW Open Access The role of DNA methylation in the pathogenesis of type 2 diabetes mellitus Sanabil Ali Hassan Ahmed1 Suraiya Anjum Ansari2 Eric P K Mensah-Brown1 and…

Open Access Das and Panda J Diabetes Metab 2014 5:9 DOI: 1041722155-61561000432 Volume 5 • Issue 9 • 1000432J Diabetes Metab ISSN: 2155-6156 JDM an open access journal…

Adipocyte T cell TLR4 Hypertrophy Hypoxia ER stress Cell death IL-1R1 Ceramide Macrophage Fetuin-A TLR4 Fetuin-A Cytokines chemokines β-cell TLR4 Glucose TLR2 Free fatty…

1 Pathophysiological mechanism of bone loss in type 2 diabetes involves inverse 1 regulation of osteoblast function by PPARγγγγ coactivator-1α and skeletal muscle 2…

Oral hypoglycemic agents in type 2 diabetes Type 2 diabetes is a disease of progressive β-cell dysfunction in presence of insulin resistance, leading to gradual loss of…

Pathogenesis of Type 1 DM Dr Abdulmoein Al-Agha Consultant Pediatric Endocrinologist King AbdulAziz University Hospital Jeddah Pathophysiology “Polygenic disorder” Pathogenesis…