Vehicle 3β-AdiolPC3 cells

Supplementary Figure S1

Annexin V positive cells

A

B

Supplementary Figure S2

A B 3β–Adiol ERE-Luciferase

Reporter(LNCaP cells)

Supplementary Figure S3

Supplementary Figure S4

Supplementary Figure S5

PC3 cells LNCaP cells A B

PC3 cellsC

B C

A

½ ERE

½ ERE

AP1

Supplementary Figure S6

chr6:109006104-109006412

Supplementary Figure S7A B

C D

E F

G H

Supplementary Figure S8A B

C D

E F