Pushing Brachytherapy

one step FurtherBryce AllredDec. 6th 2010

Brachytherapy Methods

Brachytherapy Isotopes 1910- urethral radium

1601 yr half life 1922- many complications

Au-198 γ-ray of .412 MeV Half life of 2.7 days

I-125– .027 MeV γ rays– 60 day half life

α/β Ratios -N*(α*D+β*D^2)

S= e α is the linear term

dealing with double strand break

β Is the quadratic term dealing with single strand break

New Isotopes Palladium-103 has

proven to be very effective

External beam therapy is currently compensating for lack of brachytherapy

Electrons travel finite distance A photons probability

of attenuation makes it unsafe

Electrons can treat an organ without harming other organs

Choosing Isotope Needs similarly even

distribution Energy of around 5

MeV and a half life between 10 and 40 days

Conclusion

May prove to be very effective in isolating treatment.

Computer simulations and phantom readings will be used to perform research