Phage Therapy: An innovative technology for the g py gybiological control of bacterial pathogens in

A ltAquacultureΒακτηριοφάγοι: Καινοτόμος τεχνολογία για τη βιολογική καταπολέμηση ηρ φ γ μ ς χ γ γ η β γ ή μη η

βακτηριακών ασθενειών στις Υδατοκαλλιέργειες

Bacteriophages Phage therapy Phages and aquacultureBacteriophages

• Bacteriophages (or phages) are viruses that infect bacteria

Phage therapy

• Can be a promising alternative to the use of antibiotics

Phages and aquaculture

• They can be used in delicate environments such marine hatcheriesbacteria

• They occur naturally in the water and they constitute the most numerous life form in the planet

• They are host specific and infect only the target

of antibiotics• Is method of biological control of bacterial

diseases• Leaves no residues

such marine hatcheries• They remove only the target bacteria without

destroying the normal microflora• They do not require multiple dosesThey are host specific and infect only the target

bacteria• They are self-replicating when found in an environment

rich in target bacteria

Leaves no residues• Is environmentally friendly• Is safe for humans and other life forms

They do not require multiple doses

rich in target bacteria• They are self-restricted when target bacteria are

reduced

Phage Research at the Institute of Aquaculture, HCMRPhages attacking bacteria Phage isolation at the Institute of Aquaculture Lytic activityagainst Vibrios Pathogen library

Aim: Phage cocktail that will exclude bacterial pathogens in larval rearing tanks without affecting the normal microflora

T t B t i l P th Li t ll (Vib i ) ill

Scientific responsible: Dr. P. KathariosΕπιστημονικός υπεύθυνος:

Target Bacterial Pathogens: Listonella (Vibrio) anguillarumVibrio harveyiVibrio alginolyticusPhotobacterium (Pasteurella) damselae subsp. Piscicida

Επιστημονικός υπεύθυνος: Δρ. Π. Καθάριος Research Programs: EPAL 2000-2006 Innovative Measures, Greek Ministry of Rural Development and Food

AQUAPHAGE: Network for the development of phage therapy in aquaculture. FP7 Marie Curie IRSES-2010

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