2002 fused pyridine derivatives

fused pyridine derivativesR 0450

40 - 158A New Entry to Asymmetric Synthesis of 1-Substituted 1,2,3,4-Tetrahydro-β-carbolines Employing a Pyroglutamic Acid Derivativeas a Chiral Auxiliary. — A new method for the asymmetric addition ofallyltributyltin or silyl enol ethers to β-carbolines at C-1 position is describedusing novel chiral auxiliaries derived from (S)-pyroglutamic acid. — (ITOH,TAKASHI; NAGATA, KAZUHIRO; YOKOYA, MASASHI; MIYAZAKI,MICHIKO; IKEDA, SACHIKO; MATSUYA, YUJI; ENOMOTO, YASUKO;OHSAWA, AKIO; Synlett (2002) 6, 1005-1006; Fac. Pharm. Sci., Hoshi Univ.,Shinagawa, Tokyo 142, Japan; EN)

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