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Page 1: Αμφισβητώντας τα Guidelines: MIBC squamous di fferentiation with glandular differentiation with trophoblastic differentiation Nested Microcystic Micropapillary Lym phoepith

ΑμφισβητώνταςταGuidelines:MIBC

ΒασίλειοςΤζώρτζης

Page 2: Αμφισβητώντας τα Guidelines: MIBC squamous di fferentiation with glandular differentiation with trophoblastic differentiation Nested Microcystic Micropapillary Lym phoepith

Ιστολογικοί υπότυποι

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WHO2016

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Ιστολογικοί υπότυποι

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Κλινικές πληροφορίες

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ΟρισμόςBCG-refractory

EAUGuidelines

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3και6μήνεςμετάTUR-B

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ΟρισμόςBCG-refractory

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Χρειαζόμαστεάλλεςοδηγίεςγιατιςγυναίκες;

•  4ησυχνότερηνεοπλασίαΆνδρες•  8η Γυναίκες

NajariB.JUrol2013

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Χρειαζόμαστεάλλεςοδηγίεςγιατιςγυναίκες;

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Γιατί;

•  Αναζήτησηβοήθειαςαπότηνασθενή•  Γενικοίιατροί•  Βιολογικέςδιαφορές

–  Ιστολογικοίτύποι– Οδοίμεταβολισμούκαρκινογόνων– Ορμόνες(οιστρογόνα)

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Χρειαζόμαστεάλλεςοδηγίεςγιατιςγυναίκες;

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InternasonalCollaborasonofTrialistsLancet1999GrossmanHBetalNewEnglJMed2003SherifAetalEurUrol2004

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NeoadjuvantΧημειοθεραπεία

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Πραγματικότητα

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PreoperasveRT

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PreoperasveRT

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AdjuvantΧημειοθεραπεία(μημεταστατικό)

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Πραγματικότητα

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Παρακολούθηση

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n=1290

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