T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T...

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T cell-mediated immunity

Transcript of T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T...

Page 1: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production

T cell-mediated immunity

Page 2: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 3: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production

T helper cells (Th)

T cytotoxic cells (Tc)

B cells

Macrophages

Antibody production

Phagocytosis and killing

Infected cells

help

help

kill

Page 4: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 5: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 6: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 7: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 8: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 9: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production

B CELL ACTIVATION & ANTIBODY PRODUCTION

HLA class II

CD4+

Interferon-γ

HLA class I

CD8+

Kill

HLA class II

CD4+

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Page 11: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production
Page 12: T cell-mediated immunity - University of Nottingham · 2017-04-01 · T cell-mediated immunity. T helper cells (Th) T cytotoxic cells (Tc) B cells Macrophages Antibody production

Naïve

CD80/86


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徐子真2014.4.25. AIHA CLL 10% Mechanisms of autoimmunity in CLL? normal B cells CLL cells abnormally functioning T cells microenvironment.

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Activity determination in SARS-CoV-2-reactive T cells...EQ_6841_R_UK_A01, 12/2020 Both the humoral and the cellular immune response play a decisive role in the development of immunity

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WA27041-Chimeric Antigen Receptor T cells · 2020. 12. 11. · Transfus Med Rev30, 139-145 (2016). 3. Kalos, M., et al. T cells with chimeric antigen receptors have potent antitumor

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Ly6C defines a subset of memory-like CD27 γδ T cells with … · 2020. 9. 8. · Page 3 of 46 INTRODUCTION γδ T cells are a rare population of T cell receptor (TCR)-expressing

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maturation of antigen presenting cells in mice and humans ... · a mixed-leukocyte reaction. Data cumulative from 3 separate donors. CD4 T cells CD8 T cells 0 5 10 15 20 % of proliferation

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Lecture on Innate Immunity and Inflammation - …immunology.ucsf.edu/sites/immunology.ucsf.edu/files/wysiwyg/... · Lecture on Innate Immunity and Inflammation! • Evolutionary View

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Lecture on Innate Immunity and Inflammationimmunology.ucsf.edu/sites/immunology.ucsf.edu/files/wysiwyg/... · Lecture on Innate Immunity and Inflammation! ... 6 Toll is required for

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INDUCTION OF TYPE I INTERFERONS AND VIRAL IMMUNITY

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T Cells in Inflammatory Diseases - University of Birmingham · T Cells in Inflammatory Diseases Dagmar Scheel-Toellner Rheumatology Research Group, IBR ... T cell precursor Naïve

T Cells in Inflammatory Diseases - University of Birmingham · T Cells in Inflammatory Diseases Dagmar Scheel-Toellner Rheumatology Research Group, IBR ... T cell precursor Naïve

WA27041-Production of Chimeric Antigen Receptor T cells · Antibody-bead conjugate selection 3 Courier Air transport ar e ... isolation of T cells or T cell subsets and the ... viable

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Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell ... · T cells expressing the TCR containing the γ-chain vari-able region 9 and the δ-chain variable region 2 (Vγ9Vδ2

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Antigen-Specific IFN- IL-17-Co-Producing CD4 T-Cells are the … · 2020. 9. 29. · Article Antigen-Specific IFN-/IL-17-Co-Producing CD4+ T-Cells are the Determinants for Protective

Antigen-Specific IFN- IL-17-Co-Producing CD4 T-Cells are the … · 2020. 9. 29. · Article Antigen-Specific IFN-/IL-17-Co-Producing CD4+ T-Cells are the Determinants for Protective

γδ T Cells and Tumor Microenvironment: From ...

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Ana Carolina Pagliaroni Cláudia Danella Polli Patrícia Assis Infected Cell in Trouble: Bystander Cells Ring the Bell Immunity 33, November 24, 2010.

Ana Carolina Pagliaroni Cláudia Danella Polli Patrícia Assis Infected Cell in Trouble: Bystander Cells Ring the Bell Immunity 33, November 24, 2010.