Supplementary Figure S2

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Supplementary Figure S2 DMSO 1nM 10nM 100nM Rapamycin (24hr) 0 5 10 15 20 p-AKT p-Src DMSO 1 nM 10 nM 100 nM Rapamycin (3hr) 0 1 2 3 4 5 6 p-AKT p-Src phospho : total ratio p-AKT p-Src p-S6 t-AKT t-Src t-S6 β-act DMSO 1nM 10nM 100nM Rapamycin (24hr) 0 1 2 3 4 p-AKT p-Src MCF7 BT474 MDA-MB-231 Rapamycin induction of p-AKT occurs within 1 hour and is not due to increased levels of p-Src. t-Src p-AKT t-AKT MCF7 BT474 MDA-MB-231 p-Src 0hr 0.5hr 1hr 5hr 24hr Rapamycin (10nM) 0 5 10 15 20 25 phospho:total ratio 0hr 0.5hr 1hr 5hr 24hr Rapamycin (10nM) 0 2 4 6 8 10 p-AKT p-Src 0hr 0.5hr 1hr 5hr 24hr Rapamycin (100nM) 0 10 20 30 40 p-AKT p-Src A B

description

Supplementary Figure S2. Rapamycin induction of p-AKT occurs within 1 hour and is not due to increased levels of p- Src. A. BT474. MCF7. MDA-MB-231. p-AKT. t-AKT. p- Src. t- Src. p-S6. t-S6. β -act. B. MCF7. BT474. MDA-MB-231. p-AKT. t -AKT. p- Src. t- Src. - PowerPoint PPT Presentation

Transcript of Supplementary Figure S2

Page 1: Supplementary Figure S2

Supplementary Figure S2

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Rapamycin induction of p-AKT occurs within 1 hour and is not due to increased levels of p-Src.

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