Med lez 8 insulin glucagon

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EFFETTI METABOLICI INSULINA GLUCAGONE DIABETE

description

biochemistry lesson insulin glucagon

Transcript of Med lez 8 insulin glucagon

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EFFETTI

METABOLICI

INSULINA

GLUCAGONE

DIABETE

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• GLUT2 ( pancreas )

• Glucosio 6P Glicolisi

• Variazione potenziale di membrana

• [Calcio] Intracellulare

ESOCITOSI INSULINA

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PANCREAS CELLULE β

GLUCOSIO

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• TIPO I (10%) Giovanile

?

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ORIGINE POLIGENETICA

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Recettore dell’insulina

Fosforilazione in Tyr

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Insulino-resistenza

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Diabetic Emergencies Emergency Block. DKA DKA PATHOPHYSIOLOGY Severe insulin deficiency increased glucagon promotes lipolysis Results in a massive increase.

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Metabolic effects of insulin and glucagon - LF UP Olomouc · Metabolic effects of insulin and glucagon • structure, biosynthesis, secretion • insulin dependent/independent tissues,

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1 Diabetes Mellitus Is a clinical syndrome characterized by an elevated of blood glucose due to relative or absolute deficiency of insulin. (insulin.

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A18: Antidotes in Depth · Mechanism of Action In both animals and humans, glucagon receptors can be found in the heart, brain, and pancreas. 22,33,64 Binding of glucagon to cardiac

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