LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary...

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LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer

Transcript of LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary...

Page 1: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-1

Φ

π

π

π

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Φ

See Primary and Adjuvant Treatment (LCC REC-3)

See Primary and Adjuvant Treatment (LCC REC-3)

Observe or See Primary Treatment (LCC REC-3)

Rectal Cancer

Page 2: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-2

See Primary Treatment (LCC REC-3)

See Primary Treatment (LCC REC-4)

See Primary Treatment (LCC REC-4)

See Primary Treatment (LCC REC-5)

See Primary Treatment (LCC REC-6)

Rectal Cancer

Page 3: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-3

Chemoradiotherapy

Chemoradiotherapy

Surveillance (See LCC REC-7)

High risk features include positive margins, lymphovascular invasion and poorly differentiated tumors.

Φ

Φ

Rectal Cancer

Page 4: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-4

Surveillance (See LCC REC-7)

Preoperative chemoradiation

(Neoadjuvant Chemoradiotherapy)

Chemotherapy

Reconsider adjuvant Chemoradiotherapy

Chemoradiotherapy Chemotherapy

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Φ

π

π

Rectal Cancer

Page 5: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-5

Surveillance (See LCC REC-7)

Chemoradiotherapy

Chemotherapy

Chemotherapy

Chemoradiotherapy

Chemoradiotherapy

Chemoradiotherapy

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Φ

Rectal Cancer

Page 6: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-6

Chemotherapy

Chemoradiotherapy

or

Resection of involved rectal segment

or

Diverting colostomy

or

Chemotherapy alone

Rectal Cancer

Page 7: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-7

See Workup and Treatment (LCC REC-8)

If patient is a potential candidate for resection of isolated metastasis.

High risk for recurrence (eg, lymphatic or venous invasion by tumor, or poorly differentiated tumors).

Villous polyp, polyp > 1 cm, or high grade dysplasia.

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Φ

π

Rectal Cancer

Page 8: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-8

Reevaluate chest/abdominal/pelvic CT in 3-6 months

See treatment for Documented metachronous metastases (LCC COL-8)

See treatment for Documented metachronous metastases (LCC REC-9)See treatment for

Documented metachronous metastases (LCC REC-9)

See treatment for Documented metachronous metastases (LCC REC-9)

Preoperative chemoradiotherapy Resection, if feasible

Radiation, if not given previously.

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Rectal Cancer

Page 9: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-9

See Primary Treatment (LCC REC-10)

Chemotherapy

πTherapy may be considered for a maximum of 6 months.

π

π

Rectal Cancer

Page 10: LCC REC-1 Φ π π π Φ Φ See Primary and Adjuvant Treatment (LCC REC-3) Observe or See Primary Treatment (LCC REC-3) Rectal Cancer.

LCC REC-10

Chemotherapy

Chemotherapy

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π

π

π

πTherapy may be considered for a maximum of 6 months.

Rectal Cancer